Where Are We With Human Lice? A Review of the Current State of Knowledge.


:Pediculus humanus is an obligate bloodsucking ectoparasite of human that includes two ecotypes, head louse and body louse, which differ slightly in morphology and biology, but have distinct ecologies. Phylogenetically, they are classified on six mitochondrial clades (A, B, C, D, E, and F), head louse encompasses the full genetic diversity of clades, while body louse belongs to clades A and D. Recent studies suggested that not only body louse, but also head louse can transmit disease, which warrants greater attention as a serious public health problem. The recent sequencing of body louse genome confirmed that P. humanus has the smallest genome of any hemimetabolous insect reported to date, and also revealed numerous interesting characteristics in the nuclear and mitochondrial genomes. The transcriptome analyses showed that body and head lice were almost genetically identical. Indeed, the phenotypic flexibility associated with the emergence of body lice, is probably a result of regulatory changes, perhaps epigenetic in origin, triggered by environmental signals. Current lice control strategies have proven unsuccessful. For instance, ivermectin represents a relatively new and very promising pediculicide. However, ivermectin resistance in the field has begun to be reported. Therefore, novel opportunities for pest control strategies are needed. Our objective here is to review the current state of knowledge on the biology, epidemiology, phylogeny, disease-vector and control of this fascinating and very intimate human parasite.


Amanzougaghene N,Fenollar F,Raoult D,Mediannikov O




Has Abstract


2020-01-21 00:00:00








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    authors: Gauliard E,Ouellette SP,Rueden KJ,Ladant D

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    journal_title:Frontiers in cellular and infection microbiology

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    authors: Iversen H,L' Abée-Lund TM,Aspholm M,Arnesen LP,Lindbäck T

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  • Linoleic Acid Inhibits the Release of Leishmania donovani Derived Microvesicles and Decreases Its Survival in Macrophages.

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    authors: Saini S,Rai AK

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  • Intrinsic ADE: The Dark Side of Antibody Dependent Enhancement During Dengue Infection.

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    authors: Jia Q,Horwitz MA

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    pub_type: 杂志文章,评审


    authors: Malireddi RK,Kanneganti TD

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  • Identification of the PANoptosome: A Molecular Platform Triggering Pyroptosis, Apoptosis, and Necroptosis (PANoptosis).

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    journal_title:Frontiers in cellular and infection microbiology

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    更新日期:2020-05-29 00:00:00

  • Granulomatous response to Coxiella burnetii, the agent of Q fever: the lessons from gene expression analysis.

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    pub_type: 杂志文章


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    pub_type: 杂志文章


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  • Tripartite ATP-Independent Periplasmic (TRAP) Transporters and Tripartite Tricarboxylate Transporters (TTT): From Uptake to Pathogenicity.

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    authors: Rosa LT,Bianconi ME,Thomas GH,Kelly DJ

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  • Genetic manipulation of Staphylococci-breaking through the barrier.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章,评审


    authors: Monk IR,Foster TJ

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  • Pathogenic Leptospires Modulate Protein Expression and Post-translational Modifications in Response to Mammalian Host Signals.

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  • Low Prevalence of Antibodies Against Toxoplasma gondii in Chinese Populations.

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  • Natural killer cells in experimental and human leishmaniasis.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章,评审


    authors: Bogdan C

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    pub_type: 杂志文章


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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


    authors: Giovannoni F,Ladelfa MF,Monte M,Jans DA,Hemmerich P,García C

    更新日期:2019-08-13 00:00:00

  • Intestinal epithelial cell apoptosis and loss of barrier function in the setting of altered microbiota with enteral nutrient deprivation.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章,评审


    authors: Demehri FR,Barrett M,Ralls MW,Miyasaka EA,Feng Y,Teitelbaum DH

    更新日期:2013-12-23 00:00:00

  • Who Needs a Contractile Actomyosin Ring? The Plethora of Alternative Ways to Divide a Protozoan Parasite.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章,评审


    authors: Hammarton TC

    更新日期:2019-11-21 00:00:00

  • Nocardia cyriacigeogica from Bovine Mastitis Induced In vitro Apoptosis of Bovine Mammary Epithelial Cells via Activation of Mitochondrial-Caspase Pathway.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


    authors: Chen W,Liu Y,Zhang L,Gu X,Liu G,Shahid M,Gao J,Ali T,Han B

    更新日期:2017-05-18 00:00:00

  • Changes in Gut Microbiota Prior to Influenza A Virus Infection Do Not Affect Immune Responses in Pups or Juvenile Mice.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


    authors: Fuglsang E,Pizzolla A,Krych L,Nielsen DS,Brooks AG,Frøkiær H,Reading PC

    更新日期:2018-09-12 00:00:00

  • MicroRNA-199a Inhibits Cellular Autophagy and Downregulates IFN-β Expression by Targeting TBK1 in Mycobacterium bovis Infected Cells.

    abstract::The mechanism by which microRNAs (miRNAs) modulate innate immunity and autophagy has not been fully elucidated in Mycobacterium bovis (M. bovis) infections. In this study, we identified that miR-199a inhibited key innate immune responses and autophagy in murine macrophages infected with M. bovis. Using ex vivo and in ...

    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


    authors: Wang J,Hussain T,Yue R,Liao Y,Li Q,Yao J,Song Y,Sun X,Wang N,Xu L,Sreevatsan S,Zhao D,Zhou X

    更新日期:2018-07-10 00:00:00