Where Are We With Human Lice? A Review of the Current State of Knowledge.


:Pediculus humanus is an obligate bloodsucking ectoparasite of human that includes two ecotypes, head louse and body louse, which differ slightly in morphology and biology, but have distinct ecologies. Phylogenetically, they are classified on six mitochondrial clades (A, B, C, D, E, and F), head louse encompasses the full genetic diversity of clades, while body louse belongs to clades A and D. Recent studies suggested that not only body louse, but also head louse can transmit disease, which warrants greater attention as a serious public health problem. The recent sequencing of body louse genome confirmed that P. humanus has the smallest genome of any hemimetabolous insect reported to date, and also revealed numerous interesting characteristics in the nuclear and mitochondrial genomes. The transcriptome analyses showed that body and head lice were almost genetically identical. Indeed, the phenotypic flexibility associated with the emergence of body lice, is probably a result of regulatory changes, perhaps epigenetic in origin, triggered by environmental signals. Current lice control strategies have proven unsuccessful. For instance, ivermectin represents a relatively new and very promising pediculicide. However, ivermectin resistance in the field has begun to be reported. Therefore, novel opportunities for pest control strategies are needed. Our objective here is to review the current state of knowledge on the biology, epidemiology, phylogeny, disease-vector and control of this fascinating and very intimate human parasite.


Amanzougaghene N,Fenollar F,Raoult D,Mediannikov O




Has Abstract


2020-01-21 00:00:00








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    abstract::In this original study, we retrospectively reviewed the cases of nocardiosis diagnosed through culture and next-generation sequencing (NGS) methods between 2014 and 2018 in Huashan Hospital and found out that the latter way can not only improve the detection rate of Nocardia spp. but also greatly reduce the turnaround...

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    pub_type: 杂志文章


    authors: Weng SS,Zhang HY,Ai JW,Gao Y,Liu YY,Xu B,Zhang WH

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  • Innate Immune Interactions between Bacillus anthracis and Host Neutrophils.

    abstract::Bacillus anthracis, the causative agent of anthrax, has been a focus of study in host-pathogen dynamics since the nineteenth century. While the interaction between anthrax and host macrophages has been extensively modeled, comparatively little is known about the effect of anthrax on the immune function of neutrophils,...

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    pub_type: 杂志文章


    authors: Liu JZ,Ali SR,Bier E,Nizet V

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  • Role of microRNAs in schistosomes and schistosomiasis.

    abstract::Schistosomes, a class of parasitic trematode worms, cause schistosomiasis. Accumulating evidence suggests that microRNAs (miRNAs)-small, non-coding RNAs that are known to play critical regulatory roles in many organisms-may be involved in schistosome development and sexual maturation, as well as the pathogenesis of sc...

    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章,评审


    authors: Zhu L,Liu J,Cheng G

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  • Generation of an Attenuated Tiantan Vaccinia Virus Strain by Deletion of Multiple Genes.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


    authors: Li Y,Zhu Y,Chen S,Li W,Yin X,Li S,Xiao P,Han J,Li X,Sun L,Jin N

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  • A coverslip-based technique for evaluating Staphylococcus aureus biofilm formation on human plasma.

    abstract::The ability of the opportunistic pathogen, Staphylococcus aureus, to form biofilms is increasingly being viewed as an important contributor to chronic infections. In vitro methods for analyzing S. aureus biofilm formation have focused on bacterial attachment and accumulation on abiotic surfaces, such as in microtiter ...

    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


    authors: Walker JN,Horswill AR

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  • Functional Analysis of the Chaperone-Usher Fimbrial Gene Clusters of Salmonella enterica serovar Typhi.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


    authors: Dufresne K,Saulnier-Bellemare J,Daigle F

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  • Gene flow and biological conflict systems in the origin and evolution of eukaryotes.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


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  • In vitro Interactions of Chicken Programmed Cell Death 1 (PD-1) and PD-1 Ligand-1 (PD-L1).

    abstract::In the present study, we determined the in vitro characteristics and binding interactions of chicken PD-1 (chPD-1) and PD-L1 (chPD-L1) and developed a panel of specific monoclonal antibodies against the two proteins. ChPD-1 and chPD-L1 sequence identities and similarities were lower compared with those of humans and o...

    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


    authors: Reddy VRAP,Mwangi W,Sadigh Y,Nair V

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  • The Performance of an Oral Microbiome Biomarker Panel in Predicting Oral Cavity and Oropharyngeal Cancers.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


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  • Different Phenotypes of Mature Biofilm in Flavobacterium psychrophilum Share a Potential for Virulence That Differs from Planktonic State.

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    pub_type: 杂志文章


    authors: Levipan HA,Avendaño-Herrera R

    更新日期:2017-03-15 00:00:00

  • Pathogenic Leptospires Modulate Protein Expression and Post-translational Modifications in Response to Mammalian Host Signals.

    abstract::Pathogenic species of Leptospira cause leptospirosis, a bacterial zoonotic disease with a global distribution affecting over one million people annually. Reservoir hosts of leptospirosis, including rodents, dogs, and cattle, exhibit little to no signs of disease but shed large numbers of organisms in their urine. Tran...

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    pub_type: 杂志文章


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  • How Probiotics Affect the Microbiota.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章,评审


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  • Extracellular Vesicles in Fungi: Past, Present, and Future Perspectives.

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    authors: Rizzo J,Rodrigues ML,Janbon G

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    pub_type: 杂志文章


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  • The LuxS/AI-2 Quorum-Sensing System of Streptococcus pneumoniae Is Required to Cause Disease, and to Regulate Virulence- and Metabolism-Related Genes in a Rat Model of Middle Ear Infection.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


    authors: Yadav MK,Vidal JE,Go YY,Kim SH,Chae SW,Song JJ

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  • Development of a Molecular Imprinting-Based Surface Plasmon Resonance Biosensor for Rapid and Sensitive Detection of Staphylococcus aureus Alpha Hemolysin From Human Serum.

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    pub_type: 杂志文章


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  • Targeting the Type II Secretion System: Development, Optimization, and Validation of a High-Throughput Screen for the Identification of Small Molecule Inhibitors.

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    journal_title:Frontiers in cellular and infection microbiology

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  • Vaccine delivery using nanoparticles.

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    pub_type: 杂志文章,评审


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    pub_type: 杂志文章,评审


    authors: Wang L,Yan J,Niu H,Huang R,Wu S

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  • Combination of Erythromycin and Curcumin Alleviates Staphylococcus aureus Induced Osteomyelitis in Rats.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


    authors: Zhou Z,Pan C,Lu Y,Gao Y,Liu W,Yin P,Yu X

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  • ESX-1-induced apoptosis during mycobacterial infection: to be or not to be, that is the question.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章,评审


    authors: Aguiló N,Marinova D,Martín C,Pardo J

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


    authors: Eshwar AK,Guldimann C,Oevermann A,Tasara T

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    pub_type: 杂志文章


    authors: Melkus MW,Le L,Siddiqui AJ,Molehin AJ,Zhang W,Lazarus S,Siddiqui AA

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  • The Dynamic Roles of the Inner Membrane Complex in the Multiple Stages of the Malaria Parasite.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章,评审


    authors: Ferreira JL,Heincke D,Wichers JS,Liffner B,Wilson DW,Gilberger TW

    更新日期:2021-01-08 00:00:00

  • MicroRNA-199a Inhibits Cellular Autophagy and Downregulates IFN-β Expression by Targeting TBK1 in Mycobacterium bovis Infected Cells.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


    authors: Wang J,Hussain T,Yue R,Liao Y,Li Q,Yao J,Song Y,Sun X,Wang N,Xu L,Sreevatsan S,Zhao D,Zhou X

    更新日期:2018-07-10 00:00:00

  • iTRAQ-Based Global Phosphoproteomics Reveals Novel Molecular Differences Between Toxoplasma gondii Strains of Different Genotypes.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


    authors: Wang ZX,Zhou CX,Calderón-Mantilla G,Petsalaki E,He JJ,Song HY,Elsheikha HM,Zhu XQ

    更新日期:2019-08-23 00:00:00

  • Long-Term Impact of Toxoplasma gondii Infection on Human Monocytes.

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


    authors: Ehmen HG,Lüder CGK

    更新日期:2019-06-28 00:00:00

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    journal_title:Frontiers in cellular and infection microbiology

    pub_type: 杂志文章


    authors: Huang Y,Han K,Wang W,Ren Q

    更新日期:2017-05-04 00:00:00