The Complement Binding and Inhibitory Protein CbiA of Borrelia miyamotoi Degrades Extracellular Matrix Components by Interacting with Plasmin(ogen).

abstract：:To investigate the parameters associated with post-treatment recurrence of bacterial vaginosis (BV), clinical factors and vaginal microbiota were examined and analyzed for BV patients who received standard metronidazole therapy. The variables associated with BV recurrence included clinical factors of past BV history, ...

journal_title：Frontiers in cellular and infection microbiology

authors： Xiao B,Wu C,Song W,Niu X,Qin N,Liu Z,Xu Q

更新日期：2019-06-11 00:00:00

abstract：:Relapsing fever still remains a neglected disease and little is known on its reservoir, tick vector and physiopathology in the vertebrate host. The disease occurs in temperate as well as tropical countries. Relapsing fever borreliae are spirochaetes, members of the Borreliaceae family which also contain Lyme disease s...

journal_title：Frontiers in cellular and infection microbiology

authors： Talagrand-Reboul E,Boyer PH,Bergström S,Vial L,Boulanger N

更新日期：2018-04-04 00:00:00

abstract：:The spirochete endoflagellum is a unique motility apparatus among bacteria. Despite its critical importance for pathogenesis, the full composition of the flagellum remains to be determined. We have recently reported that FcpA is a novel flagellar protein and a major component of the sheath of the filament of the spiro...

journal_title：Frontiers in cellular and infection microbiology

authors： Wunder EA Jr,Slamti L,Suwondo DN,Gibson KH,Shang Z,Sindelar CV,Trajtenberg F,Buschiazzo A,Ko AI,Picardeau M

更新日期：2018-05-08 00:00:00

abstract：:Cold shock-domain family proteins (Csps) are highly conserved nucleic acid binding proteins regulating the expression of various genes including those involved in stress resistance and virulence in bacteria. We show here that Csps are involved in virulence, cell aggregation and flagella-based extracellular motility of...

journal_title：Frontiers in cellular and infection microbiology

authors： Eshwar AK,Guldimann C,Oevermann A,Tasara T

更新日期：2017-10-26 00:00:00

abstract：:Acute pancreatitis (AP) is considered a cascade of immune responses triggered by acinar cell necrosis. AP involves two main processes of systemic inflammatory response syndrome and subsequent compensatory anti-inflammatory response syndrome. Although great efforts have been made regarding AP therapy, the mortality rat...

journal_title：Frontiers in cellular and infection microbiology

authors： Ding L,Yang Y,Li H,Wang H,Gao P

更新日期：2020-03-31 00:00:00

abstract：:Candida albicans is one of the most common fungal pathogens. Our previous study demonstrated that concomitant use of berberine (BBR) and fluconazole (FLC) showed a synergistic action against FLC-resistant C. albicans in vitro and BBR had a major antifungal effect in the synergism, while FLC played a role of increasing...

journal_title：Frontiers in cellular and infection microbiology

authors： Xu Y,Quan H,Wang Y,Zhong H,Sun J,Xu J,Jia N,Jiang Y

更新日期：2017-11-29 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) represents the etiological agent for several human malignancies, including Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman's disease (MCD), which are mostly seen in immunocompromised patients. In fact, KSHV has developed many strategies ...

journal_title：Frontiers in cellular and infection microbiology

authors： Barrett L,Chen J,Dai L,Plaisance-Bonstaff K,Del Valle L,Qin Z

更新日期：2020-10-30 00:00:00

abstract：:The Toxoplasma gondii parasitophorous vacuole membrane (PVM) offers protection from the host immune system but is also a barrier for uptake of nutrients from the host. Previously, we showed that GRA17 mediates the tachyzoite PVM permeability to small molecules. During the conversion from tachyzoites to encysted bradyz...

journal_title：Frontiers in cellular and infection microbiology

authors： Paredes-Santos T,Wang Y,Waldman B,Lourido S,Saeij JP

更新日期：2019-09-12 00:00:00

abstract：:Rheumatoid Arthritis (RA) has been increasingly associated with perturbations to the microbial communities that reside in and on the body (the microbiome), in both human and animal studies. To date, such studies have mainly focused on the microbial communities that inhabit the gut and oral cavity. Mounting evidence su...

journal_title：Frontiers in cellular and infection microbiology

authors： Hammad DBM,Hider SL,Liyanapathirana VC,Tonge DP

更新日期：2020-01-22 00:00:00

abstract：:The emergence of antimicrobial-resistant (AR) Salmonella has a major concern worldwide. This study was designed to determine the AR profiles and serovars distribution of Salmonella enterica isolated from different breeds of breeder chickens in the province of Henan, China. For this, 2,139 dead embryo samples were coll...

journal_title：Frontiers in cellular and infection microbiology

authors： Xu Y,Zhou X,Jiang Z,Qi Y,Ed-Dra A,Yue M

更新日期：2020-09-15 00:00:00

abstract：:Diethylhexylphthalate (DEHP), acting as an endocrine disruptor, disturbed reproductive health. Here, we evaluated the effects of Lactobacillus plantarum TW1-1 (L. plantarum TW1-1) on DEHP-induced testicular damage in adult male mice. Results showed that oral supplementation of L. plantarum TW1-1 significantly increase...

journal_title：Frontiers in cellular and infection microbiology

authors： Tian X,Yu Z,Feng P,Ye Z,Li R,Liu J,Hu J,Kakade A,Liu P,Li X

更新日期：2019-06-26 00:00:00

abstract：:Intraspecific differences in biological traits between Neospora caninum isolates have been widely described and associated with variations in virulence. However, the molecular basis underlying these differences has been poorly studied. We demonstrated previously that Nc-Spain7 and Nc-Spain1H, high- and low-virulence i...

journal_title：Frontiers in cellular and infection microbiology

authors： García-Sánchez M,Jiménez-Pelayo L,Horcajo P,Regidor-Cerrillo J,Collantes-Fernández E,Ortega-Mora LM

更新日期：2019-10-15 00:00:00

abstract：:Apicomplexan parasites, such as human malaria parasites, have complex lifecycles encompassing multiple and diverse environmental niches. Invading, replicating, and escaping from different cell types, along with exploiting each intracellular niche, necessitate large and dynamic changes in parasite morphology and cellul...

journal_title：Frontiers in cellular and infection microbiology

authors： Ferreira JL,Heincke D,Wichers JS,Liffner B,Wilson DW,Gilberger TW

更新日期：2021-01-08 00:00:00

abstract：:The NLRP3 inflammasome and IL-1β release have recently been suggested to be important for the progression of urinary tract infection (UTI). However, much is still unknown regarding the interaction of UPEC and the NLRP3 inflammasome. The purpose of this study was to elucidate what virulence factors uropathogenic Escher...

journal_title：Frontiers in cellular and infection microbiology

authors： Demirel I,Persson A,Brauner A,Särndahl E,Kruse R,Persson K

更新日期：2018-03-14 00:00:00

abstract：:Burkholderia mallei (Bm) is a highly infectious intracellular pathogen classified as a category B biological agent by the Centers for Disease Control and Prevention. After respiratory exposure, Bm establishes itself within host macrophages before spreading into major organ systems, which can lead to chronic infection,...

journal_title：Frontiers in cellular and infection microbiology

authors： Bozue JA,Chaudhury S,Amemiya K,Chua J,Cote CK,Toothman RG,Dankmeyer JL,Klimko CP,Wilhelmsen CL,Raymond JW,Zavaljevski N,Reifman J,Wallqvist A

更新日期：2016-02-26 00:00:00

abstract：:Chronic HCV infection is characterized by several immunological alterations, such as the accumulation of suppressor cells and of hyperactivated T lymphocytes. However, it is unclear whether direct-acting antiviral (DAA)-mediated HCV clearance restores immune dysfunctions. We performed a phenotypic characterization by ...

journal_title：Frontiers in cellular and infection microbiology

authors： Telatin V,Nicoli F,Frasson C,Menegotto N,Barbaro F,Castelli E,Erne E,Palù G,Caputo A

更新日期：2019-06-14 00:00:00

abstract：:Response regulators are a critical part of the two-component system of gene expression regulation in bacteria, transferring a signal from a sensor kinase into DNA binding activity resulting in alteration of gene expression. In this study, we investigated a previously uncharacterized response regulator in Francisella n...

journal_title：Frontiers in cellular and infection microbiology

authors： Dean SN,Milton ME,Cavanagh J,van Hoek ML

更新日期：2020-03-13 00:00:00

abstract：:Programmed cell death plays crucial roles in organismal development and host defense. Recent studies have highlighted mechanistic overlaps and extensive, multifaceted crosstalk between pyroptosis, apoptosis, and necroptosis, three programmed cell death pathways traditionally considered autonomous. The growing body of ...

journal_title：Frontiers in cellular and infection microbiology

authors： Christgen S,Zheng M,Kesavardhana S,Karki R,Malireddi RKS,Banoth B,Place DE,Briard B,Sharma BR,Tuladhar S,Samir P,Burton A,Kanneganti TD

更新日期：2020-05-29 00:00:00

abstract：:Mycoplasma bovis is an important cause of bovine respiratory disease worldwide. To understand its virulence mechanisms, we sequenced three attenuated M. bovis strains, P115, P150, and P180, which were passaged in vitro 115, 150, and 180 times, respectively, and exhibited progressively decreasing virulence. Comparative...

journal_title：Frontiers in cellular and infection microbiology

authors： Rasheed MA,Qi J,Zhu X,Chenfei H,Menghwar H,Khan FA,Zhao G,Zubair M,Hu C,Chen Y,Chen H,Guo A

更新日期：2017-05-11 00:00:00

abstract：:Deposition of Burkholderia pseudomallei within either the lungs or nasal passages of the Balb/c murine model resulted in different infection kinetics. The infection resulting from the inhalation of B. pseudomallei within a 12 μm particle aerosol was prolonged compared to a 1 μm particle aerosol with a mean time-to-dea...

journal_title：Frontiers in cellular and infection microbiology

authors： Thomas RJ,Davies C,Nunez A,Hibbs S,Eastaugh L,Harding S,Jordan J,Barnes K,Oyston P,Eley S

更新日期：2012-07-23 00:00:00

abstract：:Zoysia japonica, in Brazil, is commonly infected by Rhizoctonia solani (R. solani) in humid and cool weather conditions. Eight isolates of R. solani, previously identified as belonging to the AG2-2 LP anastomosis group, isolated from samples from large path symptoms, were collected from three counties in São Paulo sta...

journal_title：Frontiers in cellular and infection microbiology

authors： Picarelli MASC,Forgia M,Rivas EB,Nerva L,Chiapello M,Turina M,Colariccio A

更新日期：2019-07-12 00:00:00

abstract：Background:Disseminated histoplasmosis remains a major killer of immunocompromised patients in Latin America. Cytological and histological methods are usually present in most hospitals and may represent a precious diagnostic method. We report 15 years of experience of the department of pathology of the Centre Hospitali...

journal_title：Frontiers in cellular and infection microbiology

authors： Drak Alsibai K,Couppié P,Blanchet D,Adenis A,Epelboin L,Blaizot R,Louvel D,Djossou F,Demar M,Nacher M

更新日期：2020-10-29 00:00:00

abstract：:Cryptosporidium spp. and Enterocytozoon bieneusi are two important zoonotic pathogens that can infect humans and a broad range of animal hosts. However, few studies have been conducted to study infection of the two pathogens in domestic geese until now. The aims of the present study were to determine the prevalence of...

journal_title：Frontiers in cellular and infection microbiology

authors： Zhao W,Zhou HH,Ma TM,Cao J,Lu G,Shen YJ

更新日期：2019-12-04 00:00:00

abstract：:Lung microbiome ecosystem homeostasis in idiopathic pulmonary fibrosis (IPF) remains uncharacterized. The aims of this study were to identify unique microbial signatures of the lung microbiome and analyze microbial gene function in IPF patients. DNA isolated from BALF samples was obtained for high-throughput gene sequ...

journal_title：Frontiers in cellular and infection microbiology

authors： Tong X,Su F,Xu X,Xu H,Yang T,Xu Q,Dai H,Huang K,Zou L,Zhang W,Pei S,Xiao F,Li Y,Wang C

更新日期：2019-05-21 00:00:00

abstract：:Background:Staphylococcus aureus biofilms contribute negatively to a number of chronic conditions, including chronic rhinosinusitis (CRS). With the inherent tolerance of biofilm-bound bacteria to antibiotics and the global problem of bacterial antibiotic resistance, the need to develop novel therapeutics is paramount....

journal_title：Frontiers in cellular and infection microbiology

authors： Drilling AJ,Ooi ML,Miljkovic D,James C,Speck P,Vreugde S,Clark J,Wormald PJ

更新日期：2017-02-24 00:00:00

abstract：:Background: Increasing evidence has shown that Helicobacter pylori is associated with coronary heart disease (CHD); however, the underlying mechanism remains unclear. Methods: The expression of miR-25 and mRNAs was measured using qRT-PCR. Protein levels were detected using western blotting and exosomes were assessed w...

journal_title：Frontiers in cellular and infection microbiology

authors： Li N,Liu SF,Dong K,Zhang GC,Huang J,Wang ZH,Wang TJ

更新日期：2019-10-29 00:00:00

abstract：:The concept of pathogenesis has evolved considerably over recent years, and the scenario "a microbe + virulence factors = disease" is probably far from reality in a number of cases. Actual pathogens have extremely broad biological diversity and are found in all major groups of microorganisms (viruses, bacteria, fungi,...

journal_title：Frontiers in cellular and infection microbiology

authors： Vayssier-Taussat M,Albina E,Citti C,Cosson JF,Jacques MA,Lebrun MH,Le Loir Y,Ogliastro M,Petit MA,Roumagnac P,Candresse T

更新日期：2014-03-05 00:00:00

abstract：:Syf1 is a tetratricopeptide repeat (TPR) protein implicated in transcription elongation, spliceosome conformation, mRNA nuclear-cytoplasmic export and transcription-coupled DNA repair. Recently, we identified the spliceosomal components of the human parasite Entamoeba histolytica, among them is EhSyf. Molecular predic...

journal_title：Frontiers in cellular and infection microbiology

authors： Torres-Cifuentes DM,Galindo-Rosales JM,Saucedo-Cárdenas O,Valdés J

更新日期：2018-07-09 00:00:00

abstract：:LeuO is a conserved and pleiotropic transcription regulator, antagonist of the nucleoid-associated silencer protein H-NS, and important for pathogenicity and multidrug resistance in Enterobacteriaceae. Regulation of transcription of the leuO gene is complex. It is silenced by H-NS and its paralog StpA, and it is autor...

journal_title：Frontiers in cellular and infection microbiology

authors： Breddermann H,Schnetz K

更新日期：2016-09-16 00:00:00

abstract：:The human-specific pathogen Salmonella enterica serovar Typhi causes typhoid, a major public health issue in developing countries. Several aspects of its pathogenesis are still poorly understood. S. Typhi possesses 14 fimbrial gene clusters including 12 chaperone-usher fimbriae (stg, sth, bcf, fim, saf, sef, sta, stb,...

journal_title：Frontiers in cellular and infection microbiology

authors： Dufresne K,Saulnier-Bellemare J,Daigle F

更新日期：2018-02-08 00:00:00