The role of coagulation/fibrinolysis during Streptococcus pyogenes infection.

abstract：:Dermatophytoses account for nearly a quarter of all fungal infections worldwide. These difficult to treat infections of the skin, hair, and nails, are growing more resistant to conventional antifungal treatments, and when treatable, often require prolonged therapeutic regimens. For centuries, essential oils have been ...

journal_title：Frontiers in cellular and infection microbiology

authors： Parrish N,Fisher SL,Gartling A,Craig D,Boire N,Khuvis J,Riedel S,Zhang S

更新日期：2020-10-16 00:00:00

abstract：:Objectives: To evaluate metagenomic next-generation sequencing (mNGS) as a diagnostic tool in detecting pathogens from osteoarticular infection (OAI) samples. Methods: 130 samples of joint fluid, sonicate fluid, and tissue were prospectively collected from 92 patients with OAI. The performance of mNGS and microbiology...

journal_title：Frontiers in cellular and infection microbiology

authors： Huang ZD,Zhang ZJ,Yang B,Li WB,Zhang CJ,Fang XY,Zhang CF,Zhang WM,Lin JH

更新日期：2020-09-17 00:00:00

abstract：:With major advances in experimental techniques to track antigen-specific immune responses many basic questions on the kinetics of virus-specific immunity in humans remain unanswered. To gain insights into kinetics of T and B cell responses in human volunteers we combined mathematical models and experimental data from ...

journal_title：Frontiers in cellular and infection microbiology

authors： Le D,Miller JD,Ganusov VV

更新日期：2015-01-09 00:00:00

abstract：:Staphylococcus aureus is the leading etiologic agent of orthopedic implant infections. Here a ribocluster of 27 S. aureus strains underwent further molecular characterization and subtyping by multilocus sequence typing (MLST) and spa-typing. This cluster had been detected by automated ribotyping (with the EcoRI restri...

journal_title：Frontiers in cellular and infection microbiology

authors： Montanaro L,Ravaioli S,Ruppitsch W,Campoccia D,Pietrocola G,Visai L,Speziale P,Allerberger F,Arciola CR

更新日期：2016-02-16 00:00:00

abstract：:Pneumocystis pneumonia (PCP) remains the most frequent AIDS-defining illness in developed countries. This infection also occurs in non-AIDS immunosuppressed patients, e.g., those who have undergone an organ transplantation. Moreover, mild Pneumocystis jirovecii infections related to low pulmonary fungal burden, freque...

journal_title：Frontiers in cellular and infection microbiology

authors： Bonnet P,Le Gal S,Calderon E,Delhaes L,Quinio D,Robert-Gangneux F,Ramel S,Nevez G

更新日期：2020-09-29 00:00:00

abstract：Background:Disseminated histoplasmosis remains a major killer of immunocompromised patients in Latin America. Cytological and histological methods are usually present in most hospitals and may represent a precious diagnostic method. We report 15 years of experience of the department of pathology of the Centre Hospitali...

journal_title：Frontiers in cellular and infection microbiology

authors： Drak Alsibai K,Couppié P,Blanchet D,Adenis A,Epelboin L,Blaizot R,Louvel D,Djossou F,Demar M,Nacher M

更新日期：2020-10-29 00:00:00

abstract：:Interferons (IFNs) were discovered over a half-century ago as antiviral factors. The role of type I IFNs has been studied in the pathogenesis of both acute and chronic microbial infections. Deregulated type I IFN production results in a damaging cascade of cell death, inflammation, and immunological host responses tha...

journal_title：Frontiers in cellular and infection microbiology

authors： Malireddi RK,Kanneganti TD

更新日期：2013-11-12 00:00:00

abstract：:The hemorrhagic septicemic disease vibriosis caused by Vibrio anguillarum shows noticeable similarities to invasive septicemia in humans, and in this case, the V. anguillarum-host system has the potential to serve as a model for understanding native eukaryotic host-pathogen interactions. Iron acquisition, as a fierce ...

journal_title：Frontiers in cellular and infection microbiology

authors： Li Y,Ma Q

更新日期：2017-07-25 00:00:00

abstract：:Herpes simplex virus-1 (HSV-1) is a significant human pathogen. Upon infection, HSV-1 expresses its immediate early (IE) genes, and the IE transcription factor ICP4 (infectious cell protein-4) plays a pivotal role in initiating the downstream gene-expression cascade. Using live-cell time-lapse fluorescence microscopy,...

journal_title：Frontiers in cellular and infection microbiology

authors： Chaturvedi S,Engel R,Weinberger L

更新日期：2020-06-24 00:00:00

abstract：:Burkholderia cenocepacia is an opportunistic respiratory pathogen of individuals with cystic fibrosis (CF). Some strains of B. cenocepacia are highly transmissible and resistant to almost all antibiotics. Approximately one-third of B. cenocepacia infected CF patients go on to develop fatal "cepacia syndrome." During t...

journal_title：Frontiers in cellular and infection microbiology

authors： Ganesan S,Sajjan US

更新日期：2012-01-11 00:00:00

abstract：:Salmonellae are facultative intracellular pathogens that cause globally distributed diseases with massive morbidity and mortality in humans and animals. In the past decades, numerous studies were focused on host defenses against Salmonella infection. Autophagy has been demonstrated to be an important defense mechanism...

journal_title：Frontiers in cellular and infection microbiology

authors： Wang L,Yan J,Niu H,Huang R,Wu S

更新日期：2018-03-14 00:00:00

abstract：:Proton pump inhibitors (PPIs) are the standard therapy for gastroesophageal reflux disease. In adults, PPI treatment is associated with Clostridium difficile infections (CDI). In contrast to adults the microbiome of infants develops from sterility at birth toward an adult-like profile in the first years of life. The e...

journal_title：Frontiers in cellular and infection microbiology

authors： Castellani C,Singer G,Kashofer K,Huber-Zeyringer A,Flucher C,Kaiser M,Till H

更新日期：2017-10-11 00:00:00

abstract：:Ticks are vectors of pathogens affecting human and animal health worldwide. Nevertheless, the ecological and evolutionary interactions between ticks, hosts, and pathogens are largely unknown. Here, we integrated a framework to evaluate the associations of the tick Ixodes ricinus with its hosts and environmental niches...

journal_title：Frontiers in cellular and infection microbiology

authors： Estrada-Peña A,de la Fuente J,Cabezas-Cruz A

更新日期：2017-05-31 00:00:00

abstract：:Eradication of Helicobacter pylori has been found to be effective for gastric cancer prevention, but uncertainties remain about the possible adverse consequences such as the potential microbial dysbiosis. In our study, we investigated the association between gut microbiota and H. pylori-related gastric lesions in 47 s...

journal_title：Frontiers in cellular and infection microbiology

authors： Gao JJ,Zhang Y,Gerhard M,Mejias-Luque R,Zhang L,Vieth M,Ma JL,Bajbouj M,Suchanek S,Liu WD,Ulm K,Quante M,Li ZX,Zhou T,Schmid R,Classen M,Li WQ,You WC,Pan KF

更新日期：2018-06-19 00:00:00

abstract：:The Asian tiger mosquito Aedes (Stegomya) albopictus is an invasive species that has spread across the world in the last two decades, showing a great capacity to adapt to contrasting climates and environments. While demonstrated in many insects, the contribution of bacterial symbionts in Aedes ecology is a challenging...

journal_title：Frontiers in cellular and infection microbiology

authors： Minard G,Tran FH,Dubost A,Tran-Van V,Mavingui P,Moro CV

更新日期：2014-05-14 00:00:00

abstract：:Intraspecific differences in biological traits between Neospora caninum isolates have been widely described and associated with variations in virulence. However, the molecular basis underlying these differences has been poorly studied. We demonstrated previously that Nc-Spain7 and Nc-Spain1H, high- and low-virulence i...

journal_title：Frontiers in cellular and infection microbiology

authors： García-Sánchez M,Jiménez-Pelayo L,Horcajo P,Regidor-Cerrillo J,Collantes-Fernández E,Ortega-Mora LM

更新日期：2019-10-15 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fcimb.2018.00102.]. ...

journal_title：Frontiers in cellular and infection microbiology

authors： Yin Y,Zhou D

更新日期：2018-07-27 00:00:00

abstract：:Toxoplasma gondii is an important human and animal pathogen that causes life-threatening toxoplasmosis. The host immune system produces interferon-γ (IFN-γ) to inhibit T. gondii proliferation. IFN-γ-inducible indole-2,3-dioxygenase 1 (IDO1), which mediates tryptophan degradation, has a major role in anti-T. gondii imm...

journal_title：Frontiers in cellular and infection microbiology

authors： Bando H,Lee Y,Sakaguchi N,Pradipta A,Sakamoto R,Tanaka S,Ma JS,Sasai M,Yamamoto M

更新日期：2019-05-01 00:00:00

abstract：:Sepsis is a life-threatening health condition caused by infectious pathogens of the respiratory tract, and accounts for 28-50% of annual deaths in the US alone. Current treatment regimen advocates the use of corticosteroids as adjunct treatment with antibiotics, for their broad inhibitory effect on the activity and pr...

journal_title：Frontiers in cellular and infection microbiology

authors： Ngo Ndjom CG,Kantor LV,Jones HP

更新日期：2017-06-22 00:00:00

abstract：:Half of invasive fungal infections lead to death. Amongst pathogenic fungi, the most widespread species belong to the Candida genus and vary in their susceptibility to antifungal drugs. The emergence of antifungal resistance has become a major clinical problem. Therefore, the definition of susceptibility patterns is c...

journal_title：Frontiers in cellular and infection microbiology

authors： Delavy M,Dos Santos AR,Heiman CM,Coste AT

更新日期：2019-02-07 00:00:00

abstract：:The Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt) is a heterotrimeric AB2 toxin capable of inducing lymphocytes, and other cell types, to undergo cell cycle arrest and apoptosis. Exposure to Cdt results in binding to the cell surface followed by internalization and translocation of the active...

journal_title：Frontiers in cellular and infection microbiology

authors： Boesze-Battaglia K,Walker LP,Dhingra A,Kandror K,Tang HY,Shenker BJ

更新日期：2017-11-14 00:00:00

abstract：:Gut microbiota serves as a critical indicator for gut health during treatment of pathogenic bacterial infection. Both Pulsatilla Decoction (abbreviated to PD, a traditional Chinese medicine compound) and Levofloxacin Hydrochloride (LVX) were known to have therapeutic effects to intestinal infectious disease. However, ...

journal_title：Frontiers in cellular and infection microbiology

authors： Liu X,He S,Li Q,Mu X,Hu G,Dong H

更新日期：2020-06-30 00:00:00

abstract：:Differentiation between mitis group streptococci (MGS) bacteria in routine laboratory tests has become important for obtaining accurate epidemiological information on the characteristics of MGS and understanding their clinical significance. The most reliable method of MGS species identification is multilocus sequence ...

journal_title：Frontiers in cellular and infection microbiology

authors： Imai K,Nemoto R,Kodana M,Tarumoto N,Sakai J,Kawamura T,Ikebuchi K,Mitsutake K,Murakami T,Maesaki S,Fujiwara T,Hayakawa S,Hoshino T,Seki M,Maeda T

更新日期：2020-01-30 00:00:00

abstract：:Background:Staphylococcus aureus biofilms contribute negatively to a number of chronic conditions, including chronic rhinosinusitis (CRS). With the inherent tolerance of biofilm-bound bacteria to antibiotics and the global problem of bacterial antibiotic resistance, the need to develop novel therapeutics is paramount....

journal_title：Frontiers in cellular and infection microbiology

authors： Drilling AJ,Ooi ML,Miljkovic D,James C,Speck P,Vreugde S,Clark J,Wormald PJ

更新日期：2017-02-24 00:00:00

abstract：:In the last decade it has become clear that, similarly to nucleated cells, enucleated red blood cells (RBCs) are susceptible to programmed apoptotic cell death. Erythrocytic apoptosis seems to play a role in physiological clearance of aged RBCs, but it may also be implicated in anemia of different etiological sources ...

journal_title：Frontiers in cellular and infection microbiology

authors： Totino PR,Daniel-Ribeiro CT,Ferreira-da-Cruz MF

更新日期：2016-12-09 00:00:00

abstract：:The cell envelope of pathogenic bacteria is a barrier against host environmental conditions and immunity molecules, as well as the site where many virulence factors are assembled. Extracytoplasmic stress responses (ESRs) have evolved to help maintain its integrity in conditions where it might be compromised. These ESR...

journal_title：Frontiers in cellular and infection microbiology

authors： Flores-Kim J,Darwin AJ

更新日期：2012-10-10 00:00:00

abstract：:More than a decade ago a short tandem repeat-based typing method was developed for the fungus Aspergillus fumigatus. This STRAf assay is based on the analysis of nine short tandem repeat markers. Interpretation of this STRAf assay is complicated when there are only one or two differences in tandem repeat markers betwe...

journal_title：Frontiers in cellular and infection microbiology

authors： de Groot T,Meis JF

更新日期：2019-03-29 00:00:00

abstract：:The fungal pathogen Cryptococcus neoformans can cause life-threatening infections in immune compromised individuals. This pathogen is typically acquired via inhalation, and enters the respiratory tract. Innate immune cells such as macrophages and dendritic cells (DCs) are the first host cells that encounter C. neoform...

journal_title：Frontiers in cellular and infection microbiology

authors： Nelson BN,Hawkins AN,Wozniak KL

更新日期：2020-02-11 00:00:00

abstract：:The worldwide increase in antibiotic-resistant pathogens means that identification of alternative antibacterial drug targets and the subsequent development of new treatment strategies are urgently required. One such new target is the quorum sensing (QS) system. Coral microbial consortia harbor an enormous diversity of...

journal_title：Frontiers in cellular and infection microbiology

authors： Ma ZP,Song Y,Cai ZH,Lin ZJ,Lin GH,Wang Y,Zhou J

更新日期：2018-05-08 00:00:00

abstract：:During chronic human immunodeficiency virus type 1 (HIV-1) infection, upregulation of inhibitory molecules contributes to effector cell dysfunction and exhaustion. This, in combination with the ability of HIV-1 to reside dormant in cellular reservoirs and escape immune recognition, makes the pathway to HIV-1 cure part...

journal_title：Frontiers in cellular and infection microbiology

authors： Holder KA,Grant MD

更新日期：2020-05-05 00:00:00