Investigating Antifungal Susceptibility in Candida Species With MALDI-TOF MS-Based Assays.

abstract：:The human-specific pathogen Salmonella enterica serovar Typhi causes typhoid, a major public health issue in developing countries. Several aspects of its pathogenesis are still poorly understood. S. Typhi possesses 14 fimbrial gene clusters including 12 chaperone-usher fimbriae (stg, sth, bcf, fim, saf, sef, sta, stb,...

journal_title：Frontiers in cellular and infection microbiology

authors： Dufresne K,Saulnier-Bellemare J,Daigle F

更新日期：2018-02-08 00:00:00

abstract：:Intracellular bacterial pathogens (IBPs) invade and replicate in different cell types including immune cells, in particular of the innate immune system (IIS) during infection in the acute phase. However, immune cells primarily function as essential players in the highly effective and integrated host defense systems co...

journal_title：Frontiers in cellular and infection microbiology

authors： Eisenreich W,Rudel T,Heesemann J,Goebel W

更新日期：2017-07-13 00:00:00

abstract：:Candida albicans is one of the most common fungal pathogens. Our previous study demonstrated that concomitant use of berberine (BBR) and fluconazole (FLC) showed a synergistic action against FLC-resistant C. albicans in vitro and BBR had a major antifungal effect in the synergism, while FLC played a role of increasing...

journal_title：Frontiers in cellular and infection microbiology

authors： Xu Y,Quan H,Wang Y,Zhong H,Sun J,Xu J,Jia N,Jiang Y

更新日期：2017-11-29 00:00:00

abstract：:Probiotics have been used to treat a variety of diseases for decades; however, what is the rationale for their application? Such a treatment was first proposed in the early nineteenth century based on observations of decreased bifidobacterial populations in children suffering from diarrhea, suggesting that oral intake...

journal_title：Frontiers in cellular and infection microbiology

authors： Wieërs G,Belkhir L,Enaud R,Leclercq S,Philippart de Foy JM,Dequenne I,de Timary P,Cani PD

更新日期：2020-01-15 00:00:00

abstract：:Macrophages being the connecting link between innate and adaptive immune system plays a crucial role in microbial antigen presentation and orchestrates the subsequent clearance of microorganisms. Microbial invasion of macrophages trigger a plethora of signaling cascades, which interact among them to generate a dynamic...

journal_title：Frontiers in cellular and infection microbiology

authors： Saha S,Das P,BoseDasgupta S

更新日期：2020-10-20 00:00:00

abstract：:Enterohemorrhagic Escherichia coli (EHEC) O157:H7 EspF is an important multifunctional protein that destroys the tight junctions of intestinal epithelial cells and promotes host cell apoptosis. However, its molecular mechanism remains elusive. We knocked out the espF sequence (747 bp, ΔespF), N-terminal sequence (219 ...

journal_title：Frontiers in cellular and infection microbiology

authors： Wang X,Du Y,Hua Y,Fu M,Niu C,Zhang B,Zhao W,Zhang Q,Wan C

更新日期：2017-09-21 00:00:00

abstract：:Microsporidia are a group of intracellular pathogens causing self-limited and severe diseases in immunocompetent and immunocompromised individuals, respectively. A cellular type 1 adaptive response, mediated by IL-12, IFNγ, CD4+, and CD8+ T cells has been shown to be essential for host resistance, and dendritic cells ...

journal_title：Frontiers in cellular and infection microbiology

authors： Bernal CE,Zorro MM,Sierra J,Gilchrist K,Botero JH,Baena A,Ramirez-Pineda JR

更新日期：2016-02-02 00:00:00

abstract：:An attenuated vaccinia virus-MVTTEAB-was constructed by deletion of non-essential gene segments related to the immunomodulatory and virulence functions of the vaccinia virus Tiantan strain (VVTT). The shuttle plasmids pTC-EGFP, pTE-EGFP, pTA35-EGFP, pTB-EGFP, and pTA66-EGFP were constructed and combined with the early...

journal_title：Frontiers in cellular and infection microbiology

authors： Li Y,Zhu Y,Chen S,Li W,Yin X,Li S,Xiao P,Han J,Li X,Sun L,Jin N

更新日期：2017-10-31 00:00:00

abstract：:MicroRNAs (miRNAs), a group of small molecule non-encoding RNAs, are key post-transcriptional regulators of gene expression that are implicated in many biological processes. In the current study, miR-217 from Eriocheir sinensis was selected for studying its roles during host-virus interaction. Overexpression or silenc...

journal_title：Frontiers in cellular and infection microbiology

authors： Huang Y,Han K,Wang W,Ren Q

更新日期：2017-05-04 00:00:00

abstract：:Deposition of Burkholderia pseudomallei within either the lungs or nasal passages of the Balb/c murine model resulted in different infection kinetics. The infection resulting from the inhalation of B. pseudomallei within a 12 μm particle aerosol was prolonged compared to a 1 μm particle aerosol with a mean time-to-dea...

journal_title：Frontiers in cellular and infection microbiology

authors： Thomas RJ,Davies C,Nunez A,Hibbs S,Eastaugh L,Harding S,Jordan J,Barnes K,Oyston P,Eley S

更新日期：2012-07-23 00:00:00

abstract：:Zoysia japonica, in Brazil, is commonly infected by Rhizoctonia solani (R. solani) in humid and cool weather conditions. Eight isolates of R. solani, previously identified as belonging to the AG2-2 LP anastomosis group, isolated from samples from large path symptoms, were collected from three counties in São Paulo sta...

journal_title：Frontiers in cellular and infection microbiology

authors： Picarelli MASC,Forgia M,Rivas EB,Nerva L,Chiapello M,Turina M,Colariccio A

更新日期：2019-07-12 00:00:00

abstract：:Due to the importance of a rapid determination of patients infected by multidrug resistant bacteria, we evaluated two rapid diagnostic tests for the detection of third-generation cephalosporins (3GC)-resistant Enterobacterales directly from positive blood cultures within 1 h: BL-REDTM (electrochemical method) and β-LA...

journal_title：Frontiers in cellular and infection microbiology

authors： Durand C,Boudet A,Lavigne JP,Pantel A

更新日期：2020-09-11 00:00:00

abstract：:The cell surface mucin MUC1 is an important host factor limiting Helicobacter pylori (H. pylori) pathogenesis in both humans and mice by providing a protective barrier and modulating mucosal epithelial and leukocyte responses. The aim of this study was to establish the time-course of molecular events in MUC1-modulated...

journal_title：Frontiers in cellular and infection microbiology

authors： Sheng YH,Ng GZ,Summers KM,Every AL,Price G,Hasnain SZ,Sutton P,McGuckin MA

更新日期：2020-07-24 00:00:00

abstract：:Dengue fever is an Aedes mosquito-borne illness caused by any one of the four different dengue virus (DENV) serotypes (1-4) and manifests in the form of symptoms ranging from mild or asymptomatic to severe disease with vascular leakage, leading to shock, and viral hemorrhagic syndrome. Increased risk of severe disease...

journal_title：Frontiers in cellular and infection microbiology

authors： Narayan R,Tripathi S

更新日期：2020-10-02 00:00:00

abstract：:Non-optimal vaginal microbiota, as observed in bacterial vaginosis (BV), is typically characterized by a depletion of beneficial lactobacilli and an abundance of numerous anaerobes. These non-optimal conditions are associated with subclinical cervicovaginal inflammation and an increased risk of HIV infection compared ...

journal_title：Frontiers in cellular and infection microbiology

authors： Delgado-Diaz DJ,Tyssen D,Hayward JA,Gugasyan R,Hearps AC,Tachedjian G

更新日期：2020-01-10 00:00:00

abstract：:In this original study, we retrospectively reviewed the cases of nocardiosis diagnosed through culture and next-generation sequencing (NGS) methods between 2014 and 2018 in Huashan Hospital and found out that the latter way can not only improve the detection rate of Nocardia spp. but also greatly reduce the turnaround...

journal_title：Frontiers in cellular and infection microbiology

authors： Weng SS,Zhang HY,Ai JW,Gao Y,Liu YY,Xu B,Zhang WH

更新日期：2020-02-18 00:00:00

abstract：:Cryptosporidium spp. and Enterocytozoon bieneusi are two important zoonotic pathogens that can infect humans and a broad range of animal hosts. However, few studies have been conducted to study infection of the two pathogens in domestic geese until now. The aims of the present study were to determine the prevalence of...

journal_title：Frontiers in cellular and infection microbiology

authors： Zhao W,Zhou HH,Ma TM,Cao J,Lu G,Shen YJ

更新日期：2019-12-04 00:00:00

abstract：:Background: Increasing evidence has shown that Helicobacter pylori is associated with coronary heart disease (CHD); however, the underlying mechanism remains unclear. Methods: The expression of miR-25 and mRNAs was measured using qRT-PCR. Protein levels were detected using western blotting and exosomes were assessed w...

journal_title：Frontiers in cellular and infection microbiology

authors： Li N,Liu SF,Dong K,Zhang GC,Huang J,Wang ZH,Wang TJ

更新日期：2019-10-29 00:00:00

abstract：:Chlamydiae are obligate intracellular pathogens of eukaryotes. The bacteria grow in an intracellular vesicle called an inclusion, the membrane of which is heavily modified by chlamydial proteins called Incs (Inclusion membrane proteins). Incs represent 7-10% of the genomes of Chlamydia and, given their localization at...

journal_title：Frontiers in cellular and infection microbiology

authors： Gauliard E,Ouellette SP,Rueden KJ,Ladant D

更新日期：2015-02-11 00:00:00

abstract：:Murid and cricetid rodents were previously believed to be the principal reservoir hosts of hantaviruses. Recently, however, multiple newfound hantaviruses have been discovered in shrews, moles, and bats, suggesting a complex evolutionary history. Little is known about the genetic diversity and geographic distribution ...

journal_title：Frontiers in cellular and infection microbiology

authors： Kikuchi F,Aoki K,Ohdachi SD,Tsuchiya K,Motokawa M,Jogahara T,Sơn NT,Bawm S,Lin KS,Thwe TL,Gamage CD,Ranorosoa MC,Omar H,Maryanto I,Suzuki H,Tanaka-Taya K,Morikawa S,Mizutani T,Suzuki M,Yanagihara R,Arai S

更新日期：2020-08-27 00:00:00

abstract：:Background: Several studies suggested an important role of the gut microbiota in the pathophysiology of neurological disorders, implying that alteration of the gut microbiota might serve as a treatment strategy. Fecal microbiota transplantation (FMT) is currently the most effective gut microbiota intervention and an a...

journal_title：Frontiers in cellular and infection microbiology

authors： Vendrik KEW,Ooijevaar RE,de Jong PRC,Laman JD,van Oosten BW,van Hilten JJ,Ducarmon QR,Keller JJ,Kuijper EJ,Contarino MF

更新日期：2020-03-24 00:00:00

abstract：:Periodontal microorganisms not only colonize subgingival pockets, but also are detected on various mucous membranes in patients with periodontitis. The object of this pilot study was, using the next-generation sequencing of 16S RNA gene, to characterize the microbiota in two oral habitats (buccal mucosas and subgingiv...

journal_title：Frontiers in cellular and infection microbiology

authors： Wei Y,Shi M,Zhen M,Wang C,Hu W,Nie Y,Wu X

更新日期：2019-03-11 00:00:00

abstract：:The mechanism by which microRNAs (miRNAs) modulate innate immunity and autophagy has not been fully elucidated in Mycobacterium bovis (M. bovis) infections. In this study, we identified that miR-199a inhibited key innate immune responses and autophagy in murine macrophages infected with M. bovis. Using ex vivo and in ...

journal_title：Frontiers in cellular and infection microbiology

authors： Wang J,Hussain T,Yue R,Liao Y,Li Q,Yao J,Song Y,Sun X,Wang N,Xu L,Sreevatsan S,Zhao D,Zhou X

更新日期：2018-07-10 00:00:00

abstract：:Shiga toxin (Stx)-producing Escherichia coli (STEC) O157:H7 is an enteric pathogen that causes life-threatening disease in humans, with cattle being major natural reservoirs. A group of STEC O157:H7 with a dramatic combination of high virulence potentials and super-shedder bovine origin have been isolated. Here, an ST...

journal_title：Frontiers in cellular and infection microbiology

authors： Teng L,Lee S,Park D,Jeong KC

更新日期：2020-06-05 00:00:00

abstract：:In the present study, we determined the in vitro characteristics and binding interactions of chicken PD-1 (chPD-1) and PD-L1 (chPD-L1) and developed a panel of specific monoclonal antibodies against the two proteins. ChPD-1 and chPD-L1 sequence identities and similarities were lower compared with those of humans and o...

journal_title：Frontiers in cellular and infection microbiology

authors： Reddy VRAP,Mwangi W,Sadigh Y,Nair V

更新日期：2019-12-19 00:00:00

abstract：:The phenylacetic acid (PA) degradative pathway is the central pathway by which various aromatic compounds (e.g., styrene) are degraded. Upper pathways for different aromatic compounds converge at common intermediate phenylacetyl-CoA (PA-CoA), which is then metabolized to succinyl-CoA and acetyl-CoA. We previously made...

journal_title：Frontiers in cellular and infection microbiology

authors： Imolorhe IA,Cardona ST

更新日期：2011-12-14 00:00:00

abstract：:A cohort study was conducted to evaluate oral microbial diversity among toddlers aged 12-24 months, and to describe the dynamic processes of colonization, development, and stabilization of the oral microflora during tooth eruption using high-throughput sequencing technology. A total of 20 healthy toddlers aged 12 mont...

journal_title：Frontiers in cellular and infection microbiology

authors： Li F,Tao D,Feng X,Wong MCM,Lu H

更新日期：2018-12-04 00:00:00

abstract：:Hundred-thousands of fungal species are present in our environment, including normal colonizers that constitute part of the human microbiota. The homeostasis of host-fungus interactions encompasses efficient fungal sensing, tolerance at mucosal surfaces, as well as antifungal defenses. Decrease in host immune fitness ...

journal_title：Frontiers in cellular and infection microbiology

authors： Bourgeois C,Kuchler K

更新日期：2012-11-22 00:00:00

abstract：:Staphylococcus aureus is the leading etiologic agent of orthopedic implant infections. Here a ribocluster of 27 S. aureus strains underwent further molecular characterization and subtyping by multilocus sequence typing (MLST) and spa-typing. This cluster had been detected by automated ribotyping (with the EcoRI restri...

journal_title：Frontiers in cellular and infection microbiology

authors： Montanaro L,Ravaioli S,Ruppitsch W,Campoccia D,Pietrocola G,Visai L,Speziale P,Allerberger F,Arciola CR

更新日期：2016-02-16 00:00:00

abstract：:Chlamydia trachomatis is the leading cause of preventable blindness and the most common bacterial sexually transmitted infection. Different strains are associated with ocular or urogenital infections, and a proposed mechanism that may explain this tissue tropism is the active tryptophan biosynthesis pathway encoded by...

journal_title：Frontiers in cellular and infection microbiology

authors： O'Neill CE,Skilton RJ,Pearson SA,Filardo S,Andersson P,Clarke IN

更新日期：2018-12-14 00:00:00