Author Correction: Novel 2-phenyloxypyrimidine derivative induces apoptosis and autophagy via inhibiting PI3K pathway and activating MAPK/ERK signaling in hepatocellular carcinoma cells.

abstract：:Microfracture of cartilage defects may induce alterations of the subchondral bone in the mid- and long-term, yet very little is known about their onset. Possibly, these changes may be avoided by an enhanced microfracture technique with additional application of bone marrow aspirate. In this study, full-thickness chond...

journal_title：Scientific reports

authors： Gao L,Orth P,Müller-Brandt K,Goebel LK,Cucchiarini M,Madry H

更新日期：2017-03-27 00:00:00

abstract：:Osmosis is the movement of solvent across a permselective membrane induced by a solute-concentration gradient. Now in 'Forward Osmosis' it is empirically observed that the diffusion of the solute is counter to that of the solvent i.e. there is so-called "reverse salt diffusion". However it has been recently suggested,...

journal_title：Scientific reports

authors： Wu JJ,Field RW

更新日期：2019-11-11 00:00:00

abstract：:Models of biological processes are often subject to different sources of noise. Developing an understanding of the combined effects of different types of uncertainty is an open challenge. In this paper, we study a variant of the susceptible-infective-recovered model of epidemic spread, which combines both agent-to-age...

journal_title：Scientific reports

authors： Herrerías-Azcué F,Galla T

更新日期：2017-10-11 00:00:00

abstract：:There is an urgent need to quantify anthropogenic influence on forest carbon stocks. Using satellite-based radar imagery for such purposes has been challenged by the apparent loss of signal sensitivity to changes in forest aboveground volume (AGV) above a certain 'saturation' point. The causes of saturation are debate...

journal_title：Scientific reports

authors： Joshi N,Mitchard ETA,Brolly M,Schumacher J,Fernández-Landa A,Johannsen VK,Marchamalo M,Fensholt R

更新日期：2017-06-14 00:00:00

abstract：:Unexpected reactor accidents and radioisotope production and consumption have led to a continuous increase in the global-scale contamination of radionuclides. In particular, anthropogenic radioiodine has become critical due to its highly volatile mobilization and recycling in global environments, resulting in widespre...

journal_title：Scientific reports

authors： Lee SY,Lee JY,Min JH,Kim SS,Baik MH,Chung SY,Lee M,Lee Y

更新日期：2016-06-17 00:00:00

abstract：:Haemonchus contortus is arguably the most injurious helminth parasite for small ruminants. We characterized the impact of H. contortus infection on the caprine abomasal microbiome. Fourteen parasite naive goats were inoculated with 5,000 H. contortus infective larvae and followed for 50 days. Six age-matched naïve goa...

journal_title：Scientific reports

authors： Li RW,Li W,Sun J,Yu P,Baldwin RL,Urban JF

更新日期：2016-02-08 00:00:00

abstract：:Analyzing heart rate variability (HRV) in preterm infants can help track maturational changes and subclinical signatures of disease. We conducted an observational study to characterize the effect of demographic and cardiorespiratory factors on three features of HRV using a linear mixed-effects model. HRV-features were...

journal_title：Scientific reports

authors： Joshi R,Kommers D,Guo C,Bikker JW,Feijs L,van Pul C,Andriessen P

更新日期：2019-05-22 00:00:00

abstract：:The restoration of biodiversity within previously improved grasslands is an important objective worldwide. In some areas farmers receive remuneration for using specific strategies but the environmental responses to them are still uncertain. This study explored the short and long-term impacts of sheep grazing and/or ha...

journal_title：Scientific reports

authors： Rosa García R,Fraser MD

更新日期：2019-07-31 00:00:00

abstract：:DDX3, a subunit of CK1ε, phosphorylates Dvl2 to promote β-catenin activation. Overexpression of the Dvl2 protein results in potent activation of β-catenin/TCF signaling in colorectal cancer. Therefore, we hypothesized that DDX3 might promote tumor invasion via the CK1ε/Dvl2 axis due to β-catenin/TCF activation. Wester...

journal_title：Scientific reports

authors： He TY,Wu DW,Lin PL,Wang L,Huang CC,Chou MC,Lee H

更新日期：2016-02-19 00:00:00

abstract：:Hepatic stellate cells (HSC) play a key role in the development of chronic liver disease (CLD). Liraglutide, well-established in type 2 diabetes, showed anti-inflammatory and anti-oxidant properties. We evaluated the effects of liraglutide on HSC phenotype and hepatic microvascular function using diverse pre-clinical ...

journal_title：Scientific reports

authors： de Mesquita FC,Guixé-Muntet S,Fernández-Iglesias A,Maeso-Díaz R,Vila S,Hide D,Ortega-Ribera M,Rosa JL,García-Pagán JC,Bosch J,de Oliveira JR,Gracia-Sancho J

更新日期：2017-06-12 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) regulate expression of protein-coding genes in cis through chromatin modifications including DNA methylation. Here we interrogated whether lncRNA genes may regulate transcription and methylation of their flanking or overlapping protein-coding genes in livers of mice exposed to a 12-week ...

journal_title：Scientific reports

authors： Silva JP,van Booven D

更新日期：2018-08-01 00:00:00

abstract：:Demand for clinical decision support systems in medicine and self-diagnostic symptom checkers has substantially increased in recent years. Existing platforms rely on knowledge bases manually compiled through a labor-intensive process or automatically derived using simple pairwise statistics. This study explored an aut...

journal_title：Scientific reports

authors： Rotmensch M,Halpern Y,Tlimat A,Horng S,Sontag D

更新日期：2017-07-20 00:00:00

abstract：:We developed a solvothermal-induced self-assembly approach to construct three dimensional (3D) macroscopic Fe2O3 nanocubes/nitrogen-doped graphene (Fe2O3-NC/GN) aerogel as anode materials for lithium-ion batteries (LIBs). The Fe2O3 nanocubes with length of ~50 nm are homogeneously anchored on 3D GN frameworks and as s...

journal_title：Scientific reports

authors： Wang R,Xu C,Sun J,Gao L

更新日期：2014-11-25 00:00:00

abstract：:In non-growing teeth, such as mouse and human molars, primary odontoblasts are long-lived post-mitotic cells that secrete dentine throughout the life of the tooth. New odontoblast-like cells are only produced in response to a damage or trauma. Little is known about the molecular events that initiate mesenchymal stem c...

journal_title：Scientific reports

authors： Babb R,Chandrasekaran D,Carvalho Moreno Neves V,Sharpe PT

更新日期：2017-06-08 00:00:00

abstract：:A soil remediation method based on magnetic beneficiation is reported. A new magnetic solid chelator powder, FS@IDA (core-shell Fe3O4@SiO2 nanoparticles coated with iminodiacetic acid chelators), was used as a reactive magnetic carrier to selectively capture non-magnetic heavy metals in soil by chelation and removal b...

journal_title：Scientific reports

authors： Fan L,Song J,Bai W,Wang S,Zeng M,Li X,Zhou Y,Li H,Lu H

更新日期：2016-02-16 00:00:00

abstract：:The role of the actin cytoskeleton in relation to mitochondria function and dynamics is only recently beginning to be recognized. Myo19 is an actin-based motor that is bound to the outer mitochondrial membrane and promotes the localization of mitochondria to filopodia in response to glucose starvation. However, how gl...

journal_title：Scientific reports

authors： Shneyer BI,Ušaj M,Wiesel-Motiuk N,Regev R,Henn A

更新日期：2017-09-14 00:00:00

abstract：:Plants are constantly exposed to pathogens and environmental stresses. To minimize damage caused by these potentially harmful factors, plants respond by massive transcriptional reprogramming of various stress-related genes via major transcription factor families. One of the transcription factor families, WRKY, plays a...

journal_title：Scientific reports

authors： Huh SU,Lee GJ,Jung JH,Kim Y,Kim YJ,Paek KH

更新日期：2015-01-23 00:00:00

abstract：:In this study, we categorize the microbial community in mangrove sediment samples from four different locations within a vast mangrove system in Kerala, India. We compared this data to other samples taken from the other known mangrove data, a tropical rainforest, and ocean sediment. An examination of the microbial com...

journal_title：Scientific reports

authors： Imchen M,Kumavath R,Barh D,Azevedo V,Ghosh P,Viana M,Wattam AR

更新日期：2017-08-18 00:00:00

abstract：:Central visual field (CVF) loss has been linked to poorer vision-related quality of life in eyes with open-angle glaucoma (OAG) and can occur even in early-stage OAG eyes. The present study investigated whether the detection of choroidal microvasculature dropout (CMvD) during follow-up, which may be a sign of perfusio...

journal_title：Scientific reports

authors： Jo YH,Kwon J,Jeong D,Shon K,Kook MS

更新日期：2019-06-12 00:00:00

abstract：:Childhood and adolescent overweight and obesity are increasing in China, but limited information is available on its secular trends in Guangzhou. In this cross-sectional study, ten-wave successive data were obtained from the physical fitness surveillance for students in Guangzhou from 2003 to 2012. A total of 2,619,15...

journal_title：Scientific reports

authors： Zong Y,Xie R,Deng N,Liu L,Tan W,Gao Y,Yang J,Yang Y

更新日期：2017-09-21 00:00:00

abstract：:Given a reaction-diffusion system interacting via a complex network, we propose two different techniques to modify the network topology while preserving its dynamical behaviour. In the region of parameters where the homogeneous solution gets spontaneously destabilized, perturbations grow along the unstable directions ...

journal_title：Scientific reports

authors： Cencetti G,Clusella P,Fanelli D

更新日期：2018-11-01 00:00:00

abstract：:Despite the increasing number of studies conducted recently to evaluate the association between HPV infections and the risk of prostate cancer, the results remain inconclusive. Furthermore, the prevalence and distribution of overall and individual HPV types worldwide in prostate cancer has not been reported until now....

journal_title：Scientific reports

authors： Yang L,Xie S,Feng X,Chen Y,Zheng T,Dai M,Zhou CK,Hu Z,Li N,Hang D

更新日期：2015-10-06 00:00:00

abstract：:Hyperspectral imaging technique was employed to determine spatial distributions of chlorophyll (Chl), and carotenoid (Car) contents in cucumber leaves in response to angular leaf spot (ALS). Altogether, 196 hyperspectral images of cucumber leaves with five infection severities of ALS were captured by a hyperspectral i...

journal_title：Scientific reports

authors： Zhao YR,Li X,Yu KQ,Cheng F,He Y

更新日期：2016-06-10 00:00:00

abstract：:We report the impact of anti-urothelial autoantibody (AUAb) on urinary bladder phenotype in BALB/c mice deficient of the FcγRIIb and PD-1. AUAb was present in serum samples from approximately half of the double-knockout (DKO) mice, as detected by immunofluorescence and immunoblots for urothelial proteins including uro...

journal_title：Scientific reports

authors： Sugino Y,Nishikawa N,Yoshimura K,Kuno S,Hayashi Y,Yoshimura N,Okazaki T,Kanematsu A,Ogawa O

更新日期：2012-01-01 00:00:00

abstract：:Early cow-calf separation prevents much of cows' natural maternal behaviour. Early separation is thought to prevent the development of a cow-calf bond. To assess this bond, we measured motivation of dairy cows to reunite with their calf. To vary the degree of bonding, some cows were allowed continued contact with thei...

journal_title：Scientific reports

authors： Wenker ML,Bokkers EAM,Lecorps B,von Keyserlingk MAG,van Reenen CG,Verwer CM,Weary DM

更新日期：2020-08-28 00:00:00

abstract：:Study aimed to assess long-term bowel function in patients who underwent low anterior resection for cancer five and more years ago. Patients who underwent low anterior resection for rectal cancer from 2010 to 2015 at National Cancer Institute were prospectively included in our study. They were interviewed using low an...

journal_title：Scientific reports

authors： Dulskas A,Kavaliauskas P,Pilipavicius L,Jodinskas M,Mikalonis M,Samalavicius NE

更新日期：2020-07-17 00:00:00

abstract：:We report on measurements of the switching current distributions on two-dimensional superconducting NbTiN strips that are 5 nm thick and 80 nm wide. We observe that the width of the switching current distributions has a non-monotonous temperature dependence, where it is constant at the lowest temperatures up to about ...

journal_title：Scientific reports

authors： Ejrnaes M,Salvoni D,Parlato L,Massarotti D,Caruso R,Tafuri F,Yang XY,You LX,Wang Z,Pepe GP,Cristiano R

更新日期：2019-05-29 00:00:00

abstract：:Methamphetamine (METH) is a highly addictive psychostimulant that causes long-lasting effects in the brain and increases the risk of developing neurodegenerative diseases. The cellular and molecular effects of METH in the brain are functionally linked to alterations in glutamate levels. Despite the well-documented eff...

journal_title：Scientific reports

authors： Jones B,Balasubramaniam M,Lebowitz JJ,Taylor A,Villalta F,Khoshbouei H,Grueter C,Grueter B,Dash C,Pandhare J

更新日期：2021-01-14 00:00:00

abstract：:Phytic acid (PA) is the primary phosphorus (P) storage compound in the seeds of cereals and legumes. Low PA crops, which are considered an effective way to improve grain nutrient availability and combat environmental issues relating to seed P have been developed using mutational and reverse genetics approaches. Here, ...

journal_title：Scientific reports

authors： Perera I,Fukushima A,Akabane T,Horiguchi G,Seneweera S,Hirotsu N

更新日期：2019-10-16 00:00:00

abstract：:The eruptive activity of basaltic hotspot volcanoes displays major fluctuations on times scales of years to decades. Theses fluctuations are thought to reflect changes in the rate of mantle melt supply. However, the crustal filter generally masks the mantle processes involved. Here, we show that the cyclic and general...

journal_title：Scientific reports

authors： Vlastélic I,Di Muro A,Bachèlery P,Gurioli L,Auclair D,Gannoun A

更新日期：2018-09-27 00:00:00