Worldwide Prevalence of Human Papillomavirus and Relative Risk of Prostate Cancer: A Meta-analysis.

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Robertson KE,Truong CD,Craciunescu FM,Yang JH,Chiu PL,Fromme P,Hansen DT

更新日期：2020-03-02 00:00:00

abstract：:It is recently appreciated that many bacterial chemoreceptors have ligand-binding domains (LBD) of the dCACHE family, a structure with two PAS-like subdomains, one membrane-proximal and the other membrane-distal. Previous studies had implicated only the membrane-distal subdomain in ligand recognition. Here, we report ...

journal_title：Scientific reports

authors： Machuca MA,Johnson KS,Liu YC,Steer DL,Ottemann KM,Roujeinikova A

更新日期：2017-10-26 00:00:00

abstract：:Parasitism is a successful survival strategy across all kingdoms and has evolved repeatedly in angiosperms. Parasitic plants obtain nutrients from other plants and some are agricultural pests. Obligate parasites, which cannot complete their lifecycle without a host, may lack functional photosystems (holoparasites), or...

journal_title：Scientific reports

authors： Petersen G,Cuenca A,Møller IM,Seberg O

更新日期：2015-12-02 00:00:00

abstract：:Proteins are of interest in nano-bio electronic devices due to their versatile structures, exquisite functionality and specificity. However, quantum transport measurements produce conflicting results due to technical limitations whereby it is difficult to precisely determine molecular orientation, the nature of the mo...

journal_title：Scientific reports

authors： Sheu SY,Yang DY

更新日期：2017-01-04 00:00:00

abstract：:Our recent studies, using (SWRxNZB)F1 (SNF1) mice, showed a potential contribution of the gut microbiota and pro-inflammatory immune responses of the gut mucosa to systemic autoimmunity in lupus. Here, using this mouse model, we determined the abundance and the nAg reactivity of IgA antibody produced in the intestine ...

journal_title：Scientific reports

authors： Sun W,Gudi RR,Johnson BM,Vasu C

更新日期：2020-08-31 00:00:00

abstract：:Both chronic Obstruction Pulmonary Disease (COPD) and lung cancer are leading causes of death globally. Although COPD and lung cancer coexist frequently, it is unknown whether lung cancer patients with COPD harbor distinct genomic characteristics compared to those without COPD. In this study, we retrospectively analyz...

journal_title：Scientific reports

authors： Xiao D,Li F,Pan H,Liang H,Wu K,He J

更新日期：2017-05-18 00:00:00

abstract：:The TMPRSS2:ERG gene fusion is one of a series of highly promising prostate cancer (PCa) biomarker alternatives to the controversial serum PSA. Current methods for detecting TMPRSS2:ERG are limited in terms of long processing time, high cost and the need for specialized equipment. Thus, there is an unmet need for less...

journal_title：Scientific reports

authors： Koo KM,Wee EJ,Mainwaring PN,Trau M

更新日期：2016-07-29 00:00:00

abstract：:Statins are a class of oral drugs that are widely used for treatment of hypercholesterolemia. Recent clinical data suggest that chronic use of these drugs increases the frequency of new onset diabetes. Studies to define the risks of statin-induced diabetes and its underlying mechanisms are clearly necessary. We explor...

journal_title：Scientific reports

authors： Kain V,Kapadia B,Misra P,Saxena U

更新日期：2015-09-08 00:00:00

abstract：:Improving the affinity of protein-protein interactions is a challenging problem that is particularly important in the development of antibodies for diagnostic and clinical use. Here, we used structure-based computational methods to optimize the binding affinity of VHNAC1, a single-domain intracellular antibody (intrab...

journal_title：Scientific reports

authors： Mahajan SP,Meksiriporn B,Waraho-Zhmayev D,Weyant KB,Kocer I,Butler DC,Messer A,Escobedo FA,DeLisa MP

更新日期：2018-12-04 00:00:00

abstract：:Epigenetic variation is implicated in a range of non-communicable diseases, including those of the eye. However, investigating the role of epigenetic variation in central tissues, such as eye or brain, remains problematic and peripheral tissues are often used as surrogates. In this study, matched human blood and eye t...

journal_title：Scientific reports

authors： Hewitt AW,Januar V,Sexton-Oates A,Joo JE,Franchina M,Wang JJ,Liang H,Craig JE,Saffery R

更新日期：2017-04-13 00:00:00

abstract：:The known angiotensin II (AngII) physiological effect of aldosterone synthesis and secretion is mediated by either Gq/11 proteins or βarrestin1 (βarr1), both of which can couple to its type 1 receptors (AT₁Rs), present in adrenocortical zona glomerulosa (AZG) cell membranes. In the present study, we examined the relat...

journal_title：Scientific reports

authors： Dabul S,Bathgate-Siryk A,Valero TR,Jafferjee M,Sturchler E,McDonald P,Koch WJ,Lymperopoulos A

更新日期：2015-01-29 00:00:00

abstract：:Endometrial cancer is the most common gynecologic cancer in the United States and its incidence and mortality has been rising over the past decade. Few treatment options are available for patients with advanced and recurring endometrial cancers. Novel therapies, which are frequently toxic, are difficult to establish i...

journal_title：Scientific reports

authors： Wen W,Lowe G,Roberts CM,Finlay J,Han ES,Glackin CA,Dellinger TH

更新日期：2017-10-06 00:00:00

abstract：:Natural biochemical systems are ubiquitously organized both in space and time. Engineering the spatial organization of biochemistry has emerged as a key theme of synthetic biology, with numerous technologies promising improved biosynthetic pathway performance. One strategy, however, may produce disparate results for d...

journal_title：Scientific reports

authors： Jakobson CM,Tullman-Ercek D,Mangan NM

更新日期：2018-05-29 00:00:00

abstract：:Laser speckle flowmetry suffers from a debated quantification of the inverse relation between decorrelation time (τc) and blood flow velocity (V), i.e. 1/τc = αV. Using a modified microcirculation imager (integrated sidestream dark field - laser speckle contrast imaging [SDF-LSCI]), we experimentally investigate on th...

journal_title：Scientific reports

authors： Nadort A,Kalkman K,van Leeuwen TG,Faber DJ

更新日期：2016-04-29 00:00:00

abstract：:This study aimed to explore the effects of radiochemotherapy on the neurocognitive function of patients with high-grade gliomas (HGG). The mini-mental state examination (MMSE), Montreal Cognitive Assessment (MoCA), event-related potential P300 (ERP-P300), and specific MRI parameters were compared, and the associations...

journal_title：Scientific reports

authors： Bian Y,Meng L,Peng J,Li J,Wei R,Huo L,Yang H,Wang Y,Fu J,Shen L,Hong J

更新日期：2019-04-12 00:00:00

abstract：:Long-term monitoring of host-parasite interactions is important for understanding the consequences of infection on host fitness and population dynamics. In an eight-year survey of the loggerhead sea turtle (Caretta caretta) population nesting in Cabo Verde, we determined the spatiotemporal variation of Ozobranchus mar...

journal_title：Scientific reports

authors： Lockley EC,Fouda L,Correia SM,Taxonera A,Nash LN,Fairweather K,Reischig T,Durão J,Dinis H,Roque SM,Lomba JP,Dos Passos L,Cameron SJK,Stiebens VA,Eizaguirre C

更新日期：2020-10-29 00:00:00

abstract：:Color vision requires the activity of cone photoreceptors to be compared in post-receptoral circuitry. Decades of psychophysical measurements have quantified the nature of these comparative interactions on a coarse scale. How such findings generalize to a cellular scale remains unclear. To answer that question, we qua...

journal_title：Scientific reports

authors： Schmidt BP,Sabesan R,Tuten WS,Neitz J,Roorda A

更新日期：2018-06-04 00:00:00

abstract：:Aldosterone antagonists slow the progression of chronic kidney disease (CKD), but their use is limited by hyperkalemia, especially when associated with RAS inhibitors. We examined the renoprotective effects of Ly, a novel non-steroidal mineralocorticoid receptor (MR) blocker, through two experimental protocols: In Pro...

journal_title：Scientific reports

authors： Fujihara CK,Kowala MC,Breyer MD,Sena CR,Rodrigues MV,Arias SCA,Fanelli C,Malheiros DM,Jadhav PK,Montrose-Rafizadeh C,Krieger JE,Zatz R

更新日期：2017-08-11 00:00:00

abstract：:Coccolithophores are single-celled photosynthesizing marine algae, responsible for half of the calcification in the surface ocean, and exert a strong influence on the distribution of carbon among global reservoirs, and thus Earth's climate. Calcification in the surface ocean decreases the buffering capacity of seawate...

journal_title：Scientific reports

authors： McClelland HL,Barbarin N,Beaufort L,Hermoso M,Ferretti P,Greaves M,Rickaby RE

更新日期：2016-09-28 00:00:00

abstract：:The inhibitory behaviour of non-ionic sugar based N,N'-didodecyl-N,N'-digluconamideethylenediamine gemini surfactant, designated as Glu(12)-2-Glu(12) on mild steel (MS) corrosion in 3.5% NaCl at 30-60 °C was explored using weight loss, PDP, EIS and SEM/EDAX/AFM techniques. The compound inhibited the corrosion of mild ...

journal_title：Scientific reports

authors： Aslam R,Mobin M,Aslam J,Lgaz H

更新日期：2018-02-27 00:00:00

abstract：:Fairly poor data are available on the relationship between taste perception, food preferences and oral microbiota. In the present study, we investigated the hypothesis that subjects with higher responsiveness to 6-n-propylthiuracil (PROP) might be characterized by a different taste sensitivity and tongue microbiota co...

journal_title：Scientific reports

authors： Cattaneo C,Gargari G,Koirala R,Laureati M,Riso P,Guglielmetti S,Pagliarini E

更新日期：2019-03-05 00:00:00

abstract：:After its recent rediscovery, the Hula painted frog (Latonia nigriventer) has remained one of the world's rarest and least understood amphibian species. Together with its apparently low dispersal capability and highly disturbed niche, the low abundance of this living fossil calls for urgent conservation measures. We u...

journal_title：Scientific reports

authors： Perl RGB,Geffen E,Malka Y,Barocas A,Renan S,Vences M,Gafny S

更新日期：2018-04-03 00:00:00

abstract：:The rapid spread of the SARS-CoV-2 in the COVID-19 pandemic had raised questions on the route of transmission of this disease. Initial understanding was that transmission originated from respiratory droplets from an infected host to a susceptible host. However, indirect contact transmission of viable virus by fomites ...

journal_title：Scientific reports

authors： Nor NSM,Yip CW,Ibrahim N,Jaafar MH,Rashid ZZ,Mustafa N,Hamid HHA,Chandru K,Latif MT,Saw PE,Lin CY,Alhasa KM,Hashim JH,Nadzir MSM

更新日期：2021-01-28 00:00:00

abstract：:Melamine detection has attracted much attention since the discovery of the damage of melamine to human health. Herein, we have developed a sensitive homogeneous electroanalytical platform for melamine detection, which is relied on the formation of triplex molecular beacon integrated with exonuclease III (Exo III)-medi...

journal_title：Scientific reports

authors： Liu X,Song M,Li F

更新日期：2017-07-03 00:00:00

abstract：:Idiopathic pulmonary fibrosis (IPF) is a progressive disease characterized by interstitial remodeling and pulmonary dysfunction. The etiology of IPF is not completely understood but involves pathologic inflammation and subsequent failure to resolve fibrosis in response to epithelial injury. Treatments for IPF are limi...

journal_title：Scientific reports

authors： Smith JNP,Witkin MD,Jogasuria AP,Christo KF,Raffay TM,Markowitz SD,Desai AB

更新日期：2020-07-15 00:00:00

abstract：:Endogenous stress represents a major source of genome instability, but is in essence difficult to apprehend. Incorporation of labeled radionuclides into DNA constitutes a tractable model to analyze cellular responses to endogenous attacks. Here we show that incorporation of [(3)H]thymidine into CHO cells generates oxi...

journal_title：Scientific reports

authors： Saintigny Y,Chevalier F,Bravard A,Dardillac E,Laurent D,Hem S,Dépagne J,Radicella JP,Lopez BS

更新日期：2016-07-11 00:00:00

abstract：:Insulin resistance (IR) has become a global epidemic that represents a serious hazard to public health. However, the precise mechanisms modulating IR have not been fully elucidated. The present study aimed to investigate the role of transcriptional factor Twist 1 in adipocyte IR and to further explore the molecular me...

journal_title：Scientific reports

authors： Lu S,Wang H,Ren R,Shi X,Zhang Y,Ma W

更新日期：2018-08-22 00:00:00

abstract：:FcRn mediates recycling and transcytosis of IgG and albumin in various cell types. The MHC-class-I-like protein of the FcRn heterodimer is encoded by FCGRT. Few determinants of variable FCGRT expression in humans have been identified so far. In this study, we investigated the presence of DNA methylation in regulatory ...

journal_title：Scientific reports

authors： Cejas RB,Ferguson DC,Quiñones-Lombraña A,Bard JE,Blanco JG

更新日期：2019-06-17 00:00:00

abstract：:The diversity of DNA sequencing methods and algorithms for genome assemblies presents scientists with a bewildering array of choices. Here, we construct and compare eight candidate assemblies combining overlapping shotgun read data, mate-pair and Chicago libraries and four different genome assemblers to produce a high...

journal_title：Scientific reports

authors： Fernandez-Silva I,Henderson JB,Rocha LA,Simison WB

更新日期：2018-01-24 00:00:00

abstract：:To master linguistic communication, humans must acquire large vocabularies quickly and effortlessly. Efficient word learning might be facilitated by the ability to rapidly acquire novel word forms even outside the focus of attention, occurring within minutes of repetitive exposure and suggesting fast and automatic lex...

journal_title：Scientific reports

authors： Partanen EJ,Leminen A,Cook C,Shtyrov Y

更新日期：2018-10-25 00:00:00