Evaluation of the dose-related concentration approach in therapeutic drug monitoring of diuretics and β-blockers - drug classes with low adherence in antihypertensive therapy.

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Abusara Z,Andrews SHJ,Von Kossel M,Herzog W

更新日期：2019-04-09 00:00:00

abstract：:Albacore tuna (Thunnus alalunga) is an important target of tuna fisheries in the Atlantic and Indian Oceans. The commercial catch of albacore is the highest globally among all temperate tuna species, contributing around 6% in weight to global tuna catches over the last decade. The accurate assessment and management of...

journal_title：Scientific reports

authors： Nikolic N,Montes I,Lalire M,Puech A,Bodin N,Arnaud-Haond S,Kerwath S,Corse E,Gaspar P,Hollanda S,Bourjea J,West W,Bonhommeau S

更新日期：2020-09-24 00:00:00

abstract：:Remote earthquake triggering is a well-established phenomenon. Triggering is commonly identified from statistically significant increases in earthquake rate coincident with the passage of seismic energy. In establishing rate changes, short duration earthquake catalogs are commonly used, and triggered sequences are not...

journal_title：Scientific reports

authors： Pankow KL,Kilb D

更新日期：2020-03-05 00:00:00

abstract：:Production of fly ash zeolites may be an attractive method for the utilization of solid wastes from the energy sector. Different methods of synthesis often yield a variety of zeolite types, thereby affecting the properties of the resulting materials. The attention paid to carbon dioxide emission reduction technologies...

journal_title：Scientific reports

authors： Czuma N,Casanova I,Baran P,Szczurowski J,Zarębska K

更新日期：2020-02-04 00:00:00

abstract：:This research aimed to explore the potential and mechanism of heat modified sawdust combined with Festuca arundinacea for the remediation of Pb-contaminated soil. We determined Pb concentration and biochemical indices in plants and soils, analyzed microbial communities in soil, and studied Pb distribution in subcellul...

journal_title：Scientific reports

authors： Zhang Y,Wang X,Ji H

更新日期：2020-03-13 00:00:00

abstract：:Skin allergy is a chronic condition that affects about 20% of the population of the western world. This disease is caused by small reactive compounds, haptens, able to penetrate into the epidermis and modify endogenous proteins, thereby triggering an immunogenic reaction. Phenyl isothiocyanate (PITC) and ethyl isothio...

journal_title：Scientific reports

authors： Karlsson I,Samuelsson K,Ponting DJ,Törnqvist M,Ilag LL,Nilsson U

更新日期：2016-02-17 00:00:00

abstract：:YPEL3 that induces cellular senescence in both normal and tumour cells of humans may show altered expression under the influence of incidental mutations. In this study, we proposed the first structure of Native YPEL3 protein and its five possible deleterious mutants-V40M, C61Y, G98R, G108S, and A131T and predicted the...

journal_title：Scientific reports

authors： Singh A,Thakur M,Singh SK,Sharma LK,Chandra K

更新日期：2020-09-17 00:00:00

abstract：:Recent successes in malaria control have been largely attributable to the deployment of insecticide-based vector control tools such as bed nets and indoor residual spraying. Pyrethroid-treated bed nets are acutely neurotoxic to mosquitoes, inducing symptoms such as loss of coordination, paralysis, and violent spasms. ...

journal_title：Scientific reports

authors： Isaacs AT,Lynd A,Donnelly MJ

更新日期：2017-04-25 00:00:00

abstract：:To improve the performance of solar photovoltaic devices one should mitigate three types of losses: optical, electrical and thermal. However, further reducing the optical and electrical losses in modern photovoltaic devices is becoming increasingly costly. Therefore, there is a rising interest in minimizing the therma...

journal_title：Scientific reports

authors： Vaillon R,Dupré O,Cal RB,Calaf M

更新日期：2018-09-03 00:00:00

abstract：:We report abnormal magnetic field effects on electrogenerated chemiluminescence (MFEECL) based on triplet emission from the Ru(bpy)3Cl2-TPrA electrochemical system: the appearance of MFEECL after magnetic field ceases. In early studies the normal MFEECL have been observed from electrochemical systems during the applic...

journal_title：Scientific reports

authors： Pan H,Shen Y,Wang H,He L,Hu B

更新日期：2015-03-16 00:00:00

abstract：:Mountain ecosystems serve as sentinels of change, and those in the Canadian Rocky Mountains have undergone a pronounced shift over the past century. We present quantitative analyses of 81 high-resolution image pairs of systematic historic surveys and repeat photographs of Canadian Rocky Mountain habitats, measuring tr...

journal_title：Scientific reports

authors： Trant A,Higgs E,Starzomski BM

更新日期：2020-06-16 00:00:00

abstract：:Human platelet antigens (HPAs) are membranous glycoproteins considered as alloantigens due to their polymorphisms. HPA-incompatibility in multiple pregnancies or blood transfusion can induce the development of alloantibodies leading to thrombocytopenia. The frequency of HPAs varies among populations, so that deep know...

journal_title：Scientific reports

authors： Kazemi MH,Malakootikhah F,Momeni-Varposhti Z,Falak R,Delbandi AA,Tajik N

更新日期：2020-05-04 00:00:00

abstract：:Low intensity transcranial focused ultrasound (LIFU) is a promising method of non-invasive neuromodulation that uses mechanical energy to affect neuronal excitability. LIFU confers high spatial resolution and adjustable focal lengths for precise neuromodulation of discrete regions in the human brain. Before the full p...

journal_title：Scientific reports

authors： Legon W,Adams S,Bansal P,Patel PD,Hobbs L,Ai L,Mueller JK,Meekins G,Gillick BT

更新日期：2020-03-27 00:00:00

abstract：:Our study purpose was to evaluate mitochondrial (mt)DNA and RNA in peripheral blood mononuclear cells (PBMCs) and body shape changes (BSC) in HBV-infected patients. mtDNA and mtRNA were measured in PBMCs. The presence of BSC was evaluated through a questionnaire and clinical evaluation. A total of 157 subjects were en...

journal_title：Scientific reports

authors： Madeddu G,Fiore V,Melis M,Ortu S,Mannu F,Muredda AA,Garrucciu G,Bandiera F,Zaru S,Bagella P,Calvisi DF,Babudieri S

更新日期：2020-02-06 00:00:00

abstract：:The aim was to assess the cognitive dysfunction and physical disability after autologous hematopoietic stem cell transplantation (AHSCT), to explore the potential factors influencing disability regression after AHSCT and to estimate the safety of low-dose immunosuppressive therapy in highly active Multiple Sclerosis (...

journal_title：Scientific reports

authors： Giedraitiene N,Kizlaitiene R,Peceliunas V,Griskevicius L,Kaubrys G

更新日期：2020-12-04 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Kim KH,Lara-Avila S,Kang H,He H,Eklӧf J,Hong SJ,Park M,Moth-Poulsen K,Matsushita S,Akagi K,Kubatkin S,Park YW

更新日期：2020-04-10 00:00:00

abstract：:Burley tobacco (Nicotiana Tabacum) is a chlorophyll-deficiency mutant. Nitrate is one precursor of tobacco-specific nitrosamines (TSNAs) and is largely accumulated in burley tobacco. To decrease nitrate accumulation in burley tobacco, glycerol, a polyhydric alcohol compound and physiological regulating material, was s...

journal_title：Scientific reports

authors： Li Y,Chang D,Yang H,Wang J,Shi H

更新日期：2018-09-05 00:00:00

abstract：:The charge transfer from the main catalyst to the cocatalyst is a key factor to enhance catalytic activity for photocatalytic nanocomposite materials. In order to enhance the charge transfer between Bi2WO6 and graphene, we inlet MoS2 as a "stepping-stone" into Bi2WO6 and graphene. Here, we report an effective strategy...

journal_title：Scientific reports

authors： Liu M,Xue X,Yu S,Wang X,Hu X,Tian H,Chen H,Zheng W

更新日期：2017-06-16 00:00:00

abstract：:Although the use of metabarcoding to identify taxa in DNA mixtures is widely approved, its reliability in quantifying taxon abundance is still the subject of debate. In this study we investigated the relationships between the amount of pollen grains in mock solutions and the abundance of high-throughput sequence reads...

journal_title：Scientific reports

authors： Baksay S,Pornon A,Burrus M,Mariette J,Andalo C,Escaravage N

更新日期：2020-03-06 00:00:00

abstract：:Boolean networks are widely used to model gene regulatory networks and to design therapeutic intervention strategies to affect the long-term behavior of systems. In this paper, we investigate the less-studied one-bit perturbation, which falls under the category of structural intervention. Previous works focused on fin...

journal_title：Scientific reports

authors： Hu M,Shen L,Zan X,Shang X,Liu W

更新日期：2016-05-19 00:00:00

abstract：:The Edinburgh Postnatal Depression Scale (EPDS) is frequently used to screen for postpartum depression. However, its factor structure exhibits noticeable inconsistencies between studies. We examined the EPDS at two postpartum time points using a large dataset from outside Western countries. Participants were 91,063 mo...

journal_title：Scientific reports

authors： Matsumura K,Hamazaki K,Tsuchida A,Kasamatsu H,Inadera H,Japan Environment and Children’s Study (JECS) Group.

更新日期：2020-07-15 00:00:00

abstract：:The present study aimed to evaluate the accuracy and repeatability of morphological contour interpolation (MCI)-based semiautomatic segmentation method for volumetric measurements of bone grafts around dental implants. Three in vitro (one with a cylinder and two with a geometrically complex form) and four ex vivo mode...

journal_title：Scientific reports

authors： Shi JY,Li Y,Zhuang LF,Zhang X,Fan LF,Lai HC

更新日期：2020-09-10 00:00:00

abstract：:Laryngeal squamous cell carcinoma is a major medical problem worldwide. Although our understanding of genetic changes and their consequences in laryngeal cancer has opened new therapeutic pathways over the years, the diagnostic as well as treatment options still need to be improved. In our previous study, we identifie...

journal_title：Scientific reports

authors： Kostrzewska-Poczekaj M,Bednarek K,Jarmuz-Szymczak M,Bodnar M,Filas V,Marszalek A,Bartochowska A,Grenman R,Kiwerska K,Szyfter K,Giefing M

更新日期：2020-01-08 00:00:00

abstract：:The purpose of this study was to compare the performance of arrival-time-insensitive (ATI) and arrival-time-sensitive (ATS) computed tomography perfusion (CTP) algorithms in Philips IntelliSpace Portal (v9, ISP) and to investigate optimal thresholds for ATI regarding the prediction of final infarct volume (FIV). Retro...

journal_title：Scientific reports

authors： Pennig L,Thiele F,Goertz L,Laukamp KR,Perkuhn M,Kabbasch C,Schlamann M,Fink GR,Borggrefe J

更新日期：2020-06-09 00:00:00

abstract：:Biomarkers for the progression of lung function in COPD are currently scarce. Plasma fetuin-B (FETUB) was identified by iTRAQ-based proteomics and was verified by ELISA in another group. Information regarding acute exacerbation (AE) was collected in a one-year follow-up programme. FETUB concentrations (1652 ± 427 ng/m...

journal_title：Scientific reports

authors： Diao WQ,Shen N,Du YP,Liu BB,Sun XY,Xu M,He B

更新日期：2016-07-22 00:00:00

abstract：:Childhood and adolescent overweight and obesity are increasing in China, but limited information is available on its secular trends in Guangzhou. In this cross-sectional study, ten-wave successive data were obtained from the physical fitness surveillance for students in Guangzhou from 2003 to 2012. A total of 2,619,15...

journal_title：Scientific reports

authors： Zong Y,Xie R,Deng N,Liu L,Tan W,Gao Y,Yang J,Yang Y

更新日期：2017-09-21 00:00:00

abstract：:Some herbivore-induced-plant volatiles (HIPVs) compounds are vital for the functioning of an ecosystem, by triggering multi-trophic interactions for natural enemies, plants and herbivores. However, the effect of these chemicals, which play a crucial role in regulating the multi-trophic interactions between plant-herbi...

journal_title：Scientific reports

authors： Lin Y,Qasim M,Hussain M,Akutse KS,Avery PB,Dash CK,Wang L

更新日期：2017-01-12 00:00:00

abstract：:Rapid eye movement (REM) sleep is considered to preferentially reprocess emotionally arousing memories. We tested this hypothesis by cueing emotional vs. neutral memories during REM and NREM sleep and wakefulness by presenting associated verbal memory cues after learning. Here we show that cueing during NREM sleep sig...

journal_title：Scientific reports

authors： Lehmann M,Schreiner T,Seifritz E,Rasch B

更新日期：2016-12-16 00:00:00

abstract：:Loss of miR-200c is correlated to advanced cancer-subtypes due to increased EMT and decreased treatment efficacy by chemotherapeutics. As miRNAs regulate a multitude of targets, the analysis of differentially expressed proteins upon a genomic knock-out (KO) is of interest. In this study, we generated a TALENs KO of mi...

journal_title：Scientific reports

authors： Ljepoja B,García-Roman J,Sommer AK,Fröhlich T,Arnold GJ,Wagner E,Roidl A

更新日期：2018-05-02 00:00:00

abstract：:Hallucinogens induce the head-twitch response (HTR), a rapid reciprocal head movement, in mice. Although head twitches are usually identified by direct observation, they can also be assessed using a head-mounted magnet and a magnetometer. Procedures have been developed to automate the analysis of magnetometer recordin...

journal_title：Scientific reports

authors： Halberstadt AL

更新日期：2020-05-20 00:00:00