Abstract：
:Human platelet antigens (HPAs) are membranous glycoproteins considered as alloantigens due to their polymorphisms. HPA-incompatibility in multiple pregnancies or blood transfusion can induce the development of alloantibodies leading to thrombocytopenia. The frequency of HPAs varies among populations, so that deep knowledge of HPA frequencies will help us to reduce those incompatibilities. Herein, we studied the allele and genotype frequencies of HPA1-6, HPA9, and HPA15 among the Iranians with intra- and inter-populations analyses on 36 worldwide populations with diverse ethnicities. The analysis shows that the HPA2 and HPA5 have the greatest differences in genotype distribution between the Iranians and other nations, although similar to other populations, the sole allele found in HPA4, 6, and 9 is "a". Despite other HPAs, the most frequent allele in HPA15 is "b", which is also abundant in HPA3. Hierarchical clustering indicates the highest degree of global similarity in HPA genotype frequency among Iranian, Argentinian, Brazilian, and German Turkish populations. Our findings can be applied to decrease the risk of alloimmunizations and platelet disorders, especially in neonates.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Kazemi MH,Malakootikhah F,Momeni-Varposhti Z,Falak R,Delbandi AA,Tajik Ndoi
10.1038/s41598-020-64469-4subject
Has Abstractpub_date
2020-05-04 00:00:00pages
7442issue
1issn
2045-2322pii
10.1038/s41598-020-64469-4journal_volume
10pub_type
杂志文章abstract：:The development of metal-based agents has had a tremendous role in the present progress in cancer chemotherapy. One well-known example of metal-based agents is Schiff based metal complexes, which hold great promise for cancer therapy. Based on the potential of Schiff based complexes for the induction of apoptosis, thi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09097
更新日期：2015-03-13 00:00:00
abstract：:Repetitive traumatic brain injury (TBI) has been linked to late life development of chronic traumatic encephalopathy (CTE), a neurodegenerative disorder histopathologically characterized by perivascular tangles of hyperphosphorylated tau at the depth of sulci to later widespread neurofibrillary pathology. Although tau...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-40678-4
更新日期：2019-03-07 00:00:00
abstract：:Spin switching of organometallic complexes by ferromagnetic surfaces is an important topic in the area of molecular nanospintronics. Moreover, graphene has been shown as a 2D surface for physisorption of molecular magnets and strain engineering on graphene can tune the spin state of an iron porphyrin (FeP) molecule fr...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep03405
更新日期：2013-12-03 00:00:00
abstract：:Light chain (AL) amyloidosis, caused by deposition of amyloidogenic immunoglobulin light chains (LCs), is the most common systemic form in industrialized countries. Still open questions, and premises for developing targeted therapies, concern the mechanisms of amyloid formation in vivo and the bases of organ targeting...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep29096
更新日期：2016-07-04 00:00:00
abstract：:Long-term skills training is known to induce neuroplastic alterations, but it is still debated whether these changes are always modality-specific or can be supramodal components. To address this issue, we compared finger-targeted somatosensory-evoked and auditory-evoked potentials under both Go (response) and Nogo (re...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-021-81852-x
更新日期：2021-01-26 00:00:00
abstract：:Human parainfluenza type-3 virus (hPIV-3) is one of the principal aetiological agents of acute respiratory illness in infants worldwide and also shows high disease severity in the elderly and immunocompromised, but neither therapies nor vaccines are available to treat or prevent infection, respectively. Using a multid...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24138
更新日期：2016-04-07 00:00:00
abstract：:Boolean multiplex (multilevel) networks (BMNs) are currently receiving considerable attention as theoretical arguments for modeling of biological systems and system level analysis. Studying control-related problems in BMNs may not only provide new views into the intrinsic control in complex biological systems, but als...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep46495
更新日期：2017-04-28 00:00:00
abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 已发布勘误
doi：10.1038/s41598-019-46782-9
更新日期：2019-07-24 00:00:00
abstract：:Sesame is prized for its oil. Genetic improvement of sesame can be enhanced through marker-assisted breeding. However, few simple sequence repeat (SSR) markers and SSR-based genetic maps were available in sesame. In this study, 7,357 SSR markers were developed from the sesame genome and transcriptomes, and a genetic m...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-08858-2
更新日期：2017-08-21 00:00:00
abstract：:EEG is known to contain considerable inter-trial and inter-subject variability, which poses a challenge in any group-level EEG analyses. A true experimental effect must be reproducible even with variabilities in trials, sessions, and subjects. Extracting components that are reproducible across trials and subjects bene...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56962-2
更新日期：2020-01-09 00:00:00
abstract：:Indoleamine 2,3 dioxygenase-1 (IDO-1) is an enzyme in the kynurenine pathway which augments tumor-induced immune tolerance. Previous studies in childhood acute myeloid leukemia (AML) have shown a negative correlation of IDO-1 mRNA expression with outcomes. The aim of our study was to develop a practical and objective ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-12940-0
更新日期：2017-10-16 00:00:00
abstract：:Mesenchymal stromal cells (MSCs) have been considered as one of the pivotal type of cells composing the tumor microenvironment. Although contact-dependent mechanisms and paracrine factors are thought to collaborate in governing the MSCs-based effects on tumors progression, the underlying mechanisms remain largely unkn...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-23651-5
更新日期：2018-04-03 00:00:00
abstract：:Lasing behavior of optically active planar topological Weyl semimetal (TWS) is investigated in view of the Kerr and Faraday rotations. Robust topological character of TWS is revealed by the presence of Weyl nodes and relevant surface conductivities. We focus our attention on the surfaces where no Fermi arcs are formed...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-59423-3
更新日期：2020-02-20 00:00:00
abstract：:Integrated photonics promises solutions to questions of stability, complexity, and size in quantum optics. Advances in tunable and non-planar integrated platforms, such as laser-inscribed photonics, continue to bring the realisation of quantum advantages in computation and metrology ever closer, perhaps most easily se...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep09601
更新日期：2015-04-27 00:00:00
abstract：:Solution Phosphorus-31 nuclear magnetic resonance (31P NMR) spectroscopy coupled with enzymatic hydrolysis (EH) with commercially available phosphatases was used to characterize phosphorus (P) compounds in extracts of the dominant aquatic macrophytes and algae in a eutrophic lake. Total extractable organic P (Po) conc...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep37164
更新日期：2016-11-16 00:00:00
abstract：:The regeneration capacity of knee cartilage can be enhanced by applying periosteal grafts, but this effect varies depending on the different sources of the periosteal grafts applied for cartilage formation. Tibia periosteum can be used to enhance cartilage repair. However, long-term analysis has not been conducted. Th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-65448-5
更新日期：2020-05-20 00:00:00
abstract：:A correction has been published and is appended to both the HTML and PDF versions of this paper. The error has been fixed in the paper. ...
journal_title：Scientific reports
pub_type： 杂志文章,已发布勘误
doi：10.1038/s41598-017-16992-0
更新日期：2017-12-04 00:00:00
abstract：:3D printing has produced many beneficial applications for surgery. The technique´s applicability in replicating nasal cavity anatomy for clinical use has not been studied. Our aim was to determine whether 3D printing could realistically replicate the nasal cavities and the airflow passing through them from a clinical ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-57537-2
更新日期：2020-01-16 00:00:00
abstract：:We discuss subwavelength-scale semiconductor metal-optic resonators placed on the metal substrate with various top metal plate sizes. Albeit with large optical losses, addition of metal layers converts a leaky semiconductor nano-block into a highly-confined optical cavity. Optically pumped lasing action is observed wi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep31793
更新日期：2016-08-23 00:00:00
abstract：:Cells grown in three-dimensional (3D) cultures are more likely to have native cell-cell and cell-matrix interactions than in 2D cultures that impose mechanical constraints to cells. However, most 3D cultures utilise gel matrix which, while serving as a scaffold, limits application due to its solid and opaque nature an...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-21950-5
更新日期：2018-02-26 00:00:00
abstract：:The mangrove fern genus Acrostichum grows in the extremely unstable marine intertidal zone under harsh conditions, such as high salt concentrations, tidal rhythms and long-term climate changes. To explore the phylogenetic relationships and molecular mechanisms underlying adaptations in this genus, we sequenced the tra...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep35634
更新日期：2016-10-26 00:00:00
abstract：:Degradation of the biologically potent octapeptide angiotensin Ang II-(1-8) is mediated by the activities of several peptidases. The conversion of Ang II to the septapeptide Ang-(1-7) is of particular interest as the latter also confers organ protection. The conversion is catalyzed by angiotensin-converting enzyme 2 a...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep45473
更新日期：2017-04-05 00:00:00
abstract：:This work reports a facile method for preparing the new photoactive In(2)O(3) films as well as their implementation in photoelectrochemical (PEC) application. We firstly investigated the relationship between oxygen vacancies (V(O)) and PEC performance and revealed a rule between them. We found that the optimized In(2)...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep01021
更新日期：2013-01-01 00:00:00
abstract：:We aimed to analyze the associations of bone mineral density (BMD) of femoral heads, age and gender, and compare the differences in BMD between fracture side and non-fracture side by "3D Spine Exam Analysis" module in QCT Pro software. In this study, we identified patients who had undergone quantitative computed tomog...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-70144-5
更新日期：2020-08-03 00:00:00
abstract：:MicroRNAs hold great promise as biomarkers of disease. However, there are few efficient and robust methods for measuring microRNAs from low input samples. Here, we develop a high-throughput sequencing protocol that efficiently captures small RNAs while minimizing inherent biases associated with library production. The...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-38458-7
更新日期：2019-02-19 00:00:00
abstract：:Learning a skilled movement often requires changing multiple dimensions of movement in a coordinated manner. Serial training is one common approach to learning a new movement pattern, where each feature is learned in isolation from the others. Once one feature is learned, we move on to the next. However, when learning...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56319-9
更新日期：2019-12-24 00:00:00
abstract：:The aim of this study was to assess the association between the shoulder tenderness and the inflammatory changes on magnetic resonance imaging (MRI) in the rheumatoid shoulder. Forty-one shoulders of 41 patients with rheumatoid arthritis (RA) were examined. We evaluated synovitis, erosion and bone marrow edema, by cou...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-55938-6
更新日期：2019-12-20 00:00:00
abstract：:In Duchenne muscular dystrophy, progressive loss of muscle tissue is accompanied by fibrosis, chronic inflammation and reduced muscle regenerative capacity. Although much is known about the development of fibrosis and chronic inflammation in muscular dystrophy, less is known about how they are mechanistically linked t...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep24708
更新日期：2016-05-31 00:00:00
abstract：:Development of novel anti-influenza A virus (IAV) drugs with high efficiency and low toxicity is critical for preparedness against influenza outbreaks. Herein, we investigated the anti-IAV activities and mechanisms of fucoidan in vitro and in vivo. The results showed that a fucoidan KW derived from brown algae Kjellma...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep40760
更新日期：2017-01-17 00:00:00
abstract：:The nickel-titanium alloy (57Ni-43Ti in wt%) was atomized by the plasma rotating electrode process (PREP). The PREP parameters such as plasma arc current, rotating electrode speed with corresponding PREP powder size range in weight percentage analysis, powder morphology and biocapability of cells were studied by scann...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-32101-1
更新日期：2018-09-13 00:00:00
