Spatial relationship of chromosomes 9 and 22 at metaphase in patients with chronic myelogenous leukemia (CML).

abstract：:Dendritic cells (DCs) are antigen presenting cells that play a role in T-cell activation. Liver-associated natural killer T lymphocytes (NKTs) are a unique subset of lymphocytes that may be important in antitumor immunity. Hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) expresses hepatitis B virus su...

journal_title：International journal of cancer

authors： Shibolet O,Alper R,Zlotogarov L,Thalenfeld B,Engelhardt D,Rabbani E,Ilan Y

更新日期：2003-08-20 00:00:00

abstract：:In ovarian carcinomas, recurrence and acquired chemoresistance are the first leading causes of therapeutic failure and are responsible for the poor overall survival rate. Cisplatin exposure of sensitive cells has been previously associated with a down-regulation of Bcl-X(L) expression and apoptosis, whereas recurrence...

journal_title：International journal of cancer

authors： Brotin E,Meryet-Figuière M,Simonin K,Duval RE,Villedieu M,Leroy-Dudal J,Saison-Behmoaras E,Gauduchon P,Denoyelle C,Poulain L

更新日期：2010-02-15 00:00:00

abstract：:Transferrin is required for proliferation of most cells in culture. This effect is presumably mediated by the binding of transferrin to its receptor, a surface glycoprotein which is preferentially expressed by actively growing cells. Here we show that normal human fibroblasts cultured in serum, and other media contain...

journal_title：International journal of cancer

authors： Ekblom P,Thesleff I,Lehto VP,Virtanen I

更新日期：1983-01-15 00:00:00

abstract：:Interval breast cancer (IC) has a more aggressive phenotype and higher mortality than screen-detected cancer (SDC). In this case-case study, we investigated whether the size of longitudinal fluctuations in mammographic percent density (PD fluctuation) was associated with the ratio of IC versus SDC among screened women...

journal_title：International journal of cancer

authors： Strand F,Humphreys K,Eriksson M,Li J,Andersson TM,Törnberg S,Azavedo E,Shepherd J,Hall P,Czene K

更新日期：2017-01-01 00:00:00

abstract：:Suppression of apoptosis may favor the onset and progression of cancer. Survivin is an inhibitor of apoptosis that has been suggested as a novel diagnostic/prognostic marker of bladder cancer. In this study, survivin mRNA expression was measured by a sensitive real-time PCR assay in tumor tissue and urine from bladder...

journal_title：International journal of cancer

authors： Weikert S,Christoph F,Schrader M,Krause H,Miller K,Müller M

更新日期：2005-08-10 00:00:00

abstract：:Elevated plasma lipoprotein(a) has been associated with an increased risk of cardiovascular disease. We report a significant elevation of total plasma apolipoprotein(a) levels in cancer patients compared with hospitalized control patients and normal healthy blood donors. Of the cancer patients studied, 48% had levels ...

journal_title：International journal of cancer

authors： Wright LC,Sullivan DR,Muller M,Dyne M,Tattersall MH,Mountford CE

更新日期：1989-02-15 00:00:00

abstract：:ATL is a fatal malignancy of T lymphocytes caused by HTLV-I infection and remains incurable. Galectins are a family of animal lectins that function both extracellularly (by interacting with cell surface and extracellular matrix glycoproteins and glycolipids) and intracellularly (by interacting with cytoplasmic and nuc...

journal_title：International journal of cancer

authors： Okudaira T,Hirashima M,Ishikawa C,Makishi S,Tomita M,Matsuda T,Kawakami H,Taira N,Ohshiro K,Masuda M,Takasu N,Mori N

更新日期：2007-05-15 00:00:00

abstract：:Survival for breast cancer (BC) is lower in eastern than northern/central Europe, and in older than younger women. We analysed how comorbidities at diagnosis affected whether selected standard treatments (STs) were given, across Europe and over time, also assessing consequences for survival/relapse. We analysed 7581 s...

journal_title：International journal of cancer

authors： Minicozzi P,Van Eycken L,Molinie F,Innos K,Guevara M,Marcos-Gragera R,Castro C,Rapiti E,Katalinic A,Torrella A,Žagar T,Bielska-Lasota M,Giorgi Rossi P,Larrañaga N,Bastos J,Sánchez MJ,Sant M,European HR Working Group on

更新日期：2019-05-01 00:00:00

abstract：:Hypoxia is known to play important roles in the development and progression of tumors. We previously demonstrated that S100A4, a critical molecule for metastasis, was upregulated in ovarian cancer cells. Therefore, we examined the mechanisms of the upregulation of S100A4 expression in ovarian carcinoma cells, with par...

journal_title：International journal of cancer

authors： Horiuchi A,Hayashi T,Kikuchi N,Hayashi A,Fuseya C,Shiozawa T,Konishi I

更新日期：2012-10-15 00:00:00

abstract：:Murine macrophages from different anatomical sites were compared for their ability to become tumoricidal and to secrete interleukin-1 (IL-1) and tumor necrosis factor (TNF) following stimulation in vitro by several biological response modifiers (BRM). Peritoneal macrophages (PM), alveolar macrophages (AM), and tumor-i...

journal_title：International journal of cancer

authors： Brunda MJ,Sulich V,Wright RB,Palleroni AV

更新日期：1991-07-09 00:00:00

abstract：:Cigarette smoking and alcohol consumption were examined as potential risk factors in a case-control study of primary liver cancer (PLC). A total of 165 PLC cases and 465 matched controls from several US hospitals were studied. A weak but statistically significant (p less than 0.05) dose-response relationship was obser...

journal_title：International journal of cancer

authors： Yu H,Harris RE,Kabat GC,Wynder EL

更新日期：1988-09-15 00:00:00

abstract：:Malignant mesothelioma (MM) is an aggressive tumor associated with environmental or occupational exposure to asbestos fibers. Erionite is a fibrous zeolite, morphologically similar to asbestos and it is assumed to be even more carcinogenic. Onset and progression of MM has been suggested as the result of the cooperatio...

journal_title：International journal of cancer

authors： Bertino P,Marconi A,Palumbo L,Bruni BM,Barbone D,Germano S,Dogan AU,Tassi GF,Porta C,Mutti L,Gaudino G

更新日期：2007-07-01 00:00:00

abstract：:Paclitaxel exerts its cytotoxic effect by kinetic suppression of microtubules that block cells in the G2/M phase of the cell cycle and trigger apoptosis. To investigate apoptosis induced by paclitaxel in nasopharyngeal carcinoma (NPC), and its possible molecular mechanism of action, the human NPC cell lines HNE-1 (bea...

journal_title：International journal of cancer

authors： Tan G,Heqing L,Jiangbo C,Ming J,Yanhong M,Xianghe L,Hong S,Li G

更新日期：2002-01-10 00:00:00

abstract：:Although a screening program for gastric cancer, using barium X-ray examination, has been carried out widely in Japan for the past 3 decades, there is insufficient evidence to confirm its effectiveness in terms of reducing mortality. To evaluate the effectiveness of the screening, a population-based case-control study...

journal_title：International journal of cancer

authors： Fukao A,Tsubono Y,Tsuji I,HIsamichi S,Sugahara N,Takano A

更新日期：1995-01-03 00:00:00

abstract：:Epigenetic alterations play an important role in carcinogenesis. Recent studies suggested that global histone modifications are predictors of cancer recurrence in various tumor entities. Our study was performed to evaluate histone H3 lysine 4 mono-methyl (H3K4me1), -di-methyl (H3K4me2) and -trimethyl (H3K4me3) pattern...

journal_title：International journal of cancer

authors： Ellinger J,Kahl P,Mertens C,Rogenhofer S,Hauser S,Hartmann W,Bastian PJ,Büttner R,Müller SC,von Ruecker A

更新日期：2010-11-15 00:00:00

abstract：:We have separated subpopulations of macrophages from an immunogenic fibrosarcoma by the technique of unit gravity velocity sedimentation. The activation state of these subpopulations was determined by measurement of the Fc receptor avidity of adherent cells, and by their 5' nucleotidase and acid phosphatase activity. ...

journal_title：International journal of cancer

authors： Moore K,McBride WH

更新日期：1980-11-15 00:00:00

abstract：:Familial risk of pancreatic cancer has been mainly assessed through case-control studies based on reported but not medically verified cancers in family members. We used the nationwide Swedish Family-Cancer Database on 10.2 million individuals and 21,000 pancreatic cancers to calculate standardized incidence ratios (SI...

journal_title：International journal of cancer

authors： Hemminki K,Li X

更新日期：2003-02-10 00:00:00

abstract：:The association between breast cancer risk defined by the Tyrer-Cuzick score (TC) and disease prognosis is not well established. Here, we investigated the relationship between 5-year TC and disease aggressiveness and then characterized underlying molecular processes. In a case-only study (n = 2474), we studied the ass...

journal_title：International journal of cancer

authors： Ugalde-Morales E,Grassmann F,Humphreys K,Li J,Eriksson M,Tobin NP,Borg Å,Vallon-Christersson J,Hall P,Czene K

更新日期：2021-02-15 00:00:00

abstract：:Human mammary carcinoma cell lines (MCF-7) were analysed for their hormone sensitivity before and after transfection with a v-Ha-ras oncogene or with a neomycin-resistance gene followed by selection in vitro or in vivo. Our aim was to test how the expression of the ras oncogene would influence the estradiol sensitivit...

journal_title：International journal of cancer

authors： Van Roy F,Mareel M,Vleminckx K,Beyaert R,Fiers W,Devleeschouwer N,Muquardt C,Legros N,Bracke M,Leclercq G

更新日期：1990-09-15 00:00:00

abstract：:Galectin-1 and galectin-3 are galactoside-binding proteins involved in different steps of tumor progression and potential targets for therapy. We have investigated the expression of these galectins in 38 human bladder transitional-cell carcinomas of different histological grade and clinical stage and in 5 normal uroth...

journal_title：International journal of cancer

authors： Cindolo L,Benvenuto G,Salvatore P,Pero R,Salvatore G,Mirone V,Prezioso D,Altieri V,Bruni CB,Chiariotti L

更新日期：1999-02-19 00:00:00

abstract：:Obesity has been postulated to increase the risk of colorectal cancer by mechanisms involving insulin resistance and the metabolic syndrome. We examined the associations of body mass index (BMI), waist circumference, the metabolic syndrome, metabolic obesity phenotypes and homeostasis model-insulin resistance (HOMA-IR...

journal_title：International journal of cancer

authors： Kabat GC,Kim MY,Stefanick M,Ho GYF,Lane DS,Odegaard AO,Simon MS,Bea JW,Luo J,Wassertheil-Smoller S,Rohan TE

更新日期：2018-08-01 00:00:00

abstract：:Hereditary non-polyposis colorectal cancer (HNPCC) is an autosomal dominant disease characterized by early-onset colorectal tumors, primarily in the right colon, that are frequently associated with other cancers. In the absence of a reliable biomarker, clinical criteria for diagnosing HNPCC have been proposed by the I...

journal_title：International journal of cancer

authors： Percesepe A,Anti M,Marra G,Roncucci L,Pahor M,Coco C,Armelao F,Gasbarrini G,Ponz de Leon M

更新日期：1994-09-15 00:00:00

abstract：:Active oxygen (AO) is ubiquitous in nature and its many forms can act as natural carcinogens. Their effect on the transformation of a mouse myeloid progenitor cell line was studied using anchorage-independent colony formation in methylcellulose as the primary assay. Both cytotoxic and non-toxic concentrations of t-but...

journal_title：International journal of cancer

authors： Crawford DR,Greenberger JS

更新日期：1991-11-11 00:00:00

abstract：:We have examined the effect of various cell monolayers on the ability of mouse spleen cells to lyse tumor cell targets (natural cytotoxicity reaction). Natural killer (NK) cell activity was reduced by as much as 75% depending on the cell substrate, with the greatest protection afforded by endothelial cells. Cell adhes...

journal_title：International journal of cancer

authors： Kaminski M,Auerbach R

更新日期：1988-06-15 00:00:00

abstract：:High BMI is a well-known risk factor for postmenopausal breast cancer. There have been some reports of excess risk in association with weight gain and WHR, but little is known about the influence of body fatness per se. Using data from the Malmö Diet and Cancer Study, a prospective cohort study, 12,159 postmenopausal ...

journal_title：International journal of cancer

authors： Lahmann PH,Lissner L,Gullberg B,Olsson H,Berglund G

更新日期：2003-01-10 00:00:00

abstract：:The autophagy lysosome pathway is essential to maintain cell viability and homeostasis in response to many stressful environments, which is reported to play a vital role in cancer development and therapy. However, the association of genetic alterations of this pathway with risk of cancer remains unclear. Based on geno...

journal_title：International journal of cancer

authors： Tan J,Fu L,Chen H,Guan J,Chen Y,Fang J

更新日期：2018-07-01 00:00:00

abstract：:In 1984 the GBSG started a multicenter randomized trial to compare the effectiveness of 6 cycles of cyclophosphamide, methotrexate and fluorouracil (CMF) with or without radiotherapy (RT) as adjuvant treatment in node-positive breast-cancer patients treated by mastectomy. During 5 years, 199 patients were randomized. ...

journal_title：International journal of cancer

authors： Schmoor C,Bastert G,Dunst J,Bojar H,Christmann D,Unbehaun V,Tümmers G,Bauer W,Sauerbrei W,Schumacher M

更新日期：2000-05-01 00:00:00

abstract：:The high burden of cervical cancer and inadequate/suboptimal cytology screening in developing countries led to the evaluation of visual screening tests, like visual inspection with acetic acid (VIA) and Lugol's iodine (VILI). We describe the performance of VIA, VILI and cytology, carried out in a multinational project...

journal_title：International journal of cancer

authors： Deodhar K,Sankaranarayanan R,Jayant K,Jeronimo J,Thorat R,Hingmire S,Muwonge R,Chiwate A,Deshpande R,Ajit D,Kelkar R,Rekhi B,Ruben I,Malvi SG,Chinoy R,Jambhekar N,Nene BM

更新日期：2012-09-15 00:00:00

abstract：:It has been suggested that smoking is associated with estrogen-negative breast cancer but not with estrogen-positive breast cancer. A population-based case-control study was conducted in Geneva, Switzerland, to determine the relation of passive and active smoking to breast cancer when the referent unexposed category c...

journal_title：International journal of cancer

authors： Morabia A,Bernstein M,Ruiz J,Héritier S,Diebold Berger S,Borisch B

更新日期：1998-01-30 00:00:00

abstract：:The effects of combined administration of bombesin (40 micrograms/kg body weight) and the ornithine decarboxylase (ODC) inhibitor, 1,3-diaminopropane (DAP), on the development of large and small intestinal tumors and the incidence of their metastasis to the peritoneum induced by azoxymethane (AOM, 7.4 mg/kg body weigh...

journal_title：International journal of cancer

authors： Iishi H,Tatsuta M,Baba M,Uehara H,Nakaizumi A

更新日期：1994-08-15 00:00:00