The functions of hydrophobic elastic polyurethane combined with an antibacterial triclosan derivative in the dentin restoration interface.

Abstract:

:Dentin restoration produces weak interfaces because of the effects of bacterial microflora, biofilms, and mechanical, thermal, and shrinkage stresses. This results in secondary caries. Therefore, hydrophobic elastic polyurethane (PU) containing different concentrations of triclosan derivatives was synthesized and applied to solve this problem. The antibacterial PU was characterized according to its tensile strength (TS) and elasticity (ε) via a universal testing machine, and water sorption (Wsp) and solubility testing (Wsl) was performed according to ISO 4049: 2009. Additionally, this study evaluated the antibacterial properties of PU against Streptococcus mutans (ATCC35668) and Escherichia coli (ATCC25922). A marginal leakage test was performed to evaluate the leakage prevention property. As a result, the antibacterial PU showed high TS (>17 MPa), high elasticity (ε > 65%), and low Wsp (>81.06 μg/mm3) and Wsl (>11.22 μg/mm3). The PU exhibited antibacterial effects against both Streptococcus mutans and Escherichia coli. The antibacterial rates were over 90% and >99% for the 3% and 5% groups, respectively. Moreover, the marginal level of leakage was 0. Based on the mechanical properties, Wsp and Wsl values and the antibacterial properties, the 3% group exhibited satisfactory performance and has been deemed a possible solution to reduce the occurrence of secondary caries.

authors

Guo X,Cheng Q,Yu G,Wang H,Tian Z,Shi Z,Cui Z,Zhu S

doi

10.1016/j.jmbbm.2019.103471

subject

Has Abstract

pub_date

2020-02-01 00:00:00

pages

103471

eissn

1751-6161

issn

1878-0180

pii

S1751-6161(19)31190-7

journal_volume

102

pub_type

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