Stem cells from the dental apical papilla in extracellular matrix hydrogels mitigate inflammation of microglial cells.

abstract：:We propose a novel scheme to realize an optical waveguide induced by an active Raman gain (ARG) process in a four-level N-type atomic system. Because of the nature of the ARG, there are two distinct features related to the waveguide: i) It is not absorptive, on the contrary, weak gain is presented; ii) It can be impro...

journal_title：Scientific reports

authors： Cui N,Gan Z,Zhang L

更新日期：2017-10-27 00:00:00

abstract：:A novel and facile two-step strategy has been designed to prepare high performance bi-transition-metals (Fe- and Mo-) carbide supported on nitrogen-doped graphene (FeMo-NG) as electrocatalysts for oxygen reduction reactions (ORR). The as-synthesized FeMo carbide -NG catalysts exhibit excellent electrocatalytic activit...

journal_title：Scientific reports

authors： Chen M,Liu J,Zhou W,Lin J,Shen Z

更新日期：2015-05-22 00:00:00

abstract：:Copper (Cu), an essential nutrient, promotes wound healing, however, target of Cu action and underlying mechanisms remain elusive. Cu chaperone Antioxidant-1 (Atox1) in the cytosol supplies Cu to the secretory enzymes such as lysyl oxidase (LOX), while Atox1 in the nucleus functions as a Cu-dependent transcription fac...

journal_title：Scientific reports

authors： Das A,Sudhahar V,Chen GF,Kim HW,Youn SW,Finney L,Vogt S,Yang J,Kweon J,Surenkhuu B,Ushio-Fukai M,Fukai T

更新日期：2016-09-26 00:00:00

abstract：:mRNAs lacking 5' untranslated regions (leaderless mRNAs) are molecular relics of an ancient translation initiation pathway. Nevertheless, they still represent a significant portion of transcriptome in some taxons, including a number of eukaryotic species. In bacteria and archaea, the leaderless mRNAs can bind non-diss...

journal_title：Scientific reports

authors： Akulich KA,Andreev DE,Terenin IM,Smirnova VV,Anisimova AS,Makeeva DS,Arkhipova VI,Stolboushkina EA,Garber MB,Prokofjeva MM,Spirin PV,Prassolov VS,Shatsky IN,Dmitriev SE

更新日期：2016-11-28 00:00:00

abstract：:The arthropod-transmitted chikungunya virus (CHIKV) causes a flu-like disease that is characterized by incapacitating arthralgia. The re-emergence of CHIKV and the continual risk of new epidemics have reignited research in CHIKV pathogenesis. Virus-specific antibodies have been shown to control virus clearance, but an...

journal_title：Scientific reports

authors： Lum FM,Couderc T,Chia BS,Ong RY,Her Z,Chow A,Leo YS,Kam YW,Rénia L,Lecuit M,Ng LFP

更新日期：2018-01-30 00:00:00

abstract：:Targeting cancer-associated fibroblasts (CAFs), as well as the crosstalk between stroma and cancer cells, could be of value in managing cancers. Pirfenidone (PFD) is an anti-fibrotic agent for idiopathic pulmonary fibrosis. This study aimed to investigate the possibility that PFD might exert an anti-tumor effect throu...

journal_title：Scientific reports

authors： Fujiwara A,Funaki S,Fukui E,Kimura K,Kanou T,Ose N,Minami M,Shintani Y

更新日期：2020-07-02 00:00:00

abstract：:Heavy metal pollution has been a problem since the advent of modern transportation, which despite efforts to curb emissions, continues to play a critical role in environmental pollution. Copper ions (Cu2+), in particular, are one of the more prevalent metals that have widespread detrimental ramifications. From this pe...

journal_title：Scientific reports

authors： Hwang J,Hwang MP,Choi M,Seo Y,Jo Y,Son J,Hong J,Choi J

更新日期：2016-10-18 00:00:00

abstract：:Nitric oxide (NO)-induced apoptosis in neurons is an important cause of neurodegenerative disease in humans. The cold-inducible protein RBM3 mediates the protective effects of cooling on apoptosis induced by various insults. However, whether RBM3 protects neural cells from NO-induced apoptosis is unclear. This study a...

journal_title：Scientific reports

authors： Yang HJ,Ju F,Guo XX,Ma SP,Wang L,Cheng BF,Zhuang RJ,Zhang BB,Shi X,Feng ZW,Wang M

更新日期：2017-01-30 00:00:00

abstract：:Betaine alleviates high-fat diet-induced fatty liver and prenatal betaine programs offspring hepatic lipid metabolism. Excessive corticosterone (CORT) exposure causes fatty liver in chickens, yet it remains unknown whether and how prenatal betaine modulates the susceptibility of CORT-induced fatty liver later in life....

journal_title：Scientific reports

authors： Hu Y,Sun Q,Liu J,Jia Y,Cai D,Idriss AA,Omer NA,Zhao R

更新日期：2017-01-06 00:00:00

abstract：:Determining the core structure of complex network systems allows us to simplify them. Using h-bridge and h-strength measurements in a weighted network, we extract the h-backbone core structure. We find that focusing on the h-backbone in a network allows greater simplification because it has fewer edges and thus fewer ...

journal_title：Scientific reports

authors： Zhang RJ,Stanley HE,Ye FY

更新日期：2018-09-25 00:00:00

abstract：:Estradiol derived from neural aromatization of testosterone plays a key role in the organization and activation of neural structures underlying male behaviors. This study evaluated the contribution of the estrogen receptor (ER) β in estradiol-induced modulation of social and mood-related behaviors by using mice lackin...

journal_title：Scientific reports

authors： Dombret C,Naulé L,Trouillet AC,Parmentier C,Hardin-Pouzet H,Mhaouty-Kodja S

更新日期：2020-04-10 00:00:00

abstract：:Dielectric Discharge Barrier (DBD) plasma actuators are considered as one of the best active electro-hydrodynamic control devices, and are considered by many contemporary researchers. Here a simple electrostatic model, which is improved by authors, and uses the Maxwell's and the Navier-Stokes equations, is proposed fo...

journal_title：Scientific reports

authors： Omidi J,Mazaheri K

更新日期：2020-11-02 00:00:00

abstract：:Pantoea sp. IMH is the only bacterium found in genus Pantoea with a high As resistance capacity, but its molecular mechanism is unknown. Herein, the organization, function, and evolution of ars genes in IMH are studied starting with analysis of the whole genome. Two ars systems - ars1 (arsR1B1C1H1) and ars2 (arsR2B2C2...

journal_title：Scientific reports

authors： Wang L,Zhuang X,Zhuang G,Jing C

更新日期：2016-12-14 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Fernandes TFD,Saavedra-Villanueva O,Margeat E,Milhiet PE,Costa L

更新日期：2020-10-22 00:00:00

abstract：:LL37 exerts a dual pathogenic role in psoriasis. Bound to self-DNA/RNA, LL37 licenses autoreactivity by stimulating plasmacytoid dendritic cells-(pDCs)-Type I interferon (IFN-I) and acts as autoantigen for pathogenic Th17-cells. In systemic lupus erythematosus (SLE), LL37 also triggers IFN-I in pDCs and is target of p...

journal_title：Scientific reports

authors： Lande R,Palazzo R,Gestermann N,Jandus C,Falchi M,Spadaro F,Riccieri V,James EA,Butera A,Boirivant M,Feldmeyer L,Surbeck I,Di Lucca J,Stuber F,Spinelli FR,Botti E,Marinari B,Bianchi L,Pica R,Cerbelli B,Giannakakis

更新日期：2020-04-03 00:00:00

abstract：:In this study, genomic DNA was screened from Halobacillus andaensis NEAU-ST10-40T by selection in Escherichia coli KNabc lacking three major Na+/H+ antiporters. One gene designated upf0118 exhibiting Na+(Li+)/H+ antiport activity was finally cloned. Protein alignment showed that UPF0118 shares the highest identity of ...

journal_title：Scientific reports

authors： Dong P,Wang L,Song N,Yang L,Chen J,Yan M,Chen H,Zhang R,Li J,Abdel-Motaal H,Jiang J

更新日期：2017-04-04 00:00:00

abstract：:Chemotherapy is widely used in cancer treatments. However, non-specific distribution of chemotherapeutic agents to healthy tissues and normal cells in the human body always leads to adverse side effects and disappointing therapeutic outcomes. Therefore, the main aim of this study was to develop a targeted drug deliver...

journal_title：Scientific reports

authors： Gan BK,Rullah K,Yong CY,Ho KL,Omar AR,Alitheen NB,Tan WS

更新日期：2020-10-08 00:00:00

abstract：:We report a theoretical and experimental study of the aggregation kinetics of oppositely charged nanoparticles. Kinetic Monte Carlo simulations are performed for symmetric, charge-asymmetric and size-asymmetric systems of oppositely charged nanoparticles. Simulation results show that both the weight and number average...

journal_title：Scientific reports

authors： Singh K,Raghav A,Jha PK,Satapathi S

更新日期：2019-03-06 00:00:00

abstract：:Olfactory receptors (ORs) mediate olfactory chemo-sensation in OR neurons. Herein, we have demonstrated that the OR chemo-sensing machinery functions in pancreatic β-cells and modulates insulin secretion. First, we found several OR isoforms, including OLFR15 and OLFR821, to be expressed in pancreatic islets and a β-ce...

journal_title：Scientific reports

authors： Munakata Y,Yamada T,Imai J,Takahashi K,Tsukita S,Shirai Y,Kodama S,Asai Y,Sugisawa T,Chiba Y,Kaneko K,Uno K,Sawada S,Hatakeyama H,Kanzaki M,Miyazaki JI,Oka Y,Katagiri H

更新日期：2018-01-24 00:00:00

abstract：:Greater levels of solar energy storage provide an effective solution to the inherent nature of intermittency, and can substantially improve reliability, availability, and quality of the renewable energy source. Here we demonstrated an all-vanadium (all-V) continuous-flow photoelectrochemical storage cell (PESC) to ach...

journal_title：Scientific reports

authors： Wei Z,Shen Y,Liu D,Liu F

更新日期：2017-04-04 00:00:00

abstract：:The comet assay is an electrophoretic technique used to assess DNA damage, as a marker of genotoxicity and oxidative stress, in tissues and biological samples including peripheral blood mononuclear cells (PBMCs) and whole blood (WB). Although numerous studies are performed on stored samples, the impact of cryopreserva...

journal_title：Scientific reports

authors： Marino M,Gigliotti L,Møller P,Riso P,Porrini M,Del Bo C

更新日期：2021-01-11 00:00:00

abstract：:Early diagnosis of dementia including Alzheimer's disease (AD) is an urgent medical and welfare issue. However, to date, no simple biometrics have been available. We reported that blood DNA methylation levels of the COASY gene, which encodes coenzyme A synthase, were increased in individuals with AD and amnestic mild ...

journal_title：Scientific reports

authors： Kobayashi N,Shinagawa S,Niimura H,Kida H,Nagata T,Tagai K,Shimada K,Oka N,Shikimoto R,Noda Y,Nakajima S,Mimura M,Shigeta M,Kondo K

更新日期：2020-07-22 00:00:00

abstract：:By applying a slow curing process, we show that biomolecules can be incorporated via a simple process as liquid stable phases inside a polydimethylsiloxane (PDMS) matrix. The process is carried out under mild conditions with regards to temperature, pH and relative humidity, and is thus suitable for application to biol...

journal_title：Scientific reports

authors： Faccio G,Cont A,Mailand E,Zare-Eelanjegh E,Innocenti Malini R,Maniura-Weber K,Rossi RM,Spano F

更新日期：2019-11-26 00:00:00

abstract：:Linearly polarized microwave radiation is shown to have its plane of polarization converted to the orthogonal state upon reflection from an ultrathin (λ/25) cavity array. The structure benefits from an uncomplicated design consisting of a metallic grating closely separated from a ground plane by a dielectric spacer. A...

journal_title：Scientific reports

authors： Tremain B,Rance HJ,Hibbins AP,Sambles JR

更新日期：2015-03-23 00:00:00

abstract：:Spatial tuning properties of retinal ganglion cells (RGCs) are sharpened by lateral inhibition originating at both the outer and inner plexiform layers. Lateral inhibition in the retina contributes to local contrast enhancement and sharpens edges. In this study, we used dynamic clamp recordings to examine the contribu...

journal_title：Scientific reports

authors： Huang JY,Protti DA

更新日期：2016-02-24 00:00:00

abstract：:The synaptic protein SHANK3 encodes a multidomain scaffold protein expressed at the postsynaptic density of neuronal excitatory synapses. We previously identified de novo SHANK3 mutations in patients with autism spectrum disorders (ASD) and showed that SHANK3 represents one of the major genes for ASD. Here, we analyze...

journal_title：Scientific reports

authors： Gouder L,Vitrac A,Goubran-Botros H,Danckaert A,Tinevez JY,André-Leroux G,Atanasova E,Lemière N,Biton A,Leblond CS,Poulet A,Boland A,Deleuze JF,Benchoua A,Delorme R,Bourgeron T,Cloëz-Tayarani I

更新日期：2019-01-14 00:00:00

abstract：:Plasmodium falciparum merozoite invasion into erythrocytes is an essential step of the blood-stage cycle, survival of parasites, and malaria pathogenesis. P. falciparum merozoite Rh5 interacting protein (PfRipr) forms a complex with Rh5 and CyRPA in sequential molecular events leading to erythrocyte invasion. Recently...

journal_title：Scientific reports

authors： Nagaoka H,Kanoi BN,Ntege EH,Aoki M,Fukushima A,Tsuboi T,Takashima E

更新日期：2020-04-20 00:00:00

abstract：:CIC-DUX4 sarcoma (CDS) is a group of rare, mesenchymal, small round cell tumours that harbour the unique CIC-DUX4 translocation, which causes aberrant gene expression. CDS exhibits an aggressive course and poor clinical outcome, thus novel therapeutic approaches are needed for CDS treatment. Although patient-derived c...

journal_title：Scientific reports

authors： Oyama R,Takahashi M,Yoshida A,Sakumoto M,Takai Y,Kito F,Shiozawa K,Qiao Z,Arai Y,Shibata T,Araki Y,Endo M,Kawai A,Kondo T

更新日期：2017-07-05 00:00:00

abstract：:The non-enzymatic browning, namely Maillard reaction is commonly invoked to account for abiotic chemical transformations of organic matter. Here we report a new reaction pathway via the Maillard reaction to systematically synthesize a series of nitrogen-doped carbon dots (C-dots) with superhigh quantum yield (QY) and ...

journal_title：Scientific reports

authors： Wei W,Xu C,Wu L,Wang J,Ren J,Qu X

更新日期：2014-01-06 00:00:00

abstract：:Cross-border equity and long-term debt securities portfolio investment networks are analysed from 2002 to 2012, covering the 2008 global financial crisis. They serve as network-proxies for measuring the robustness of the global financial system and the interdependence of financial markets, respectively. Two early-warn...

journal_title：Scientific reports

authors： Joseph AC,Joseph SE,Chen G

更新日期：2014-02-10 00:00:00