Three new compounds from Dictamnus dasycarpus and their anti-inflammatory activities.

Abstract:

:Three new compounds (1-3), named dasycarine G (1), dasycarether (2), and dasycarester (3), along with seven known compounds (4-10) obtained from the genus Dictamnus for the first time, were isolated from the root bark of Dictamnus dasycarpus. Their structures were elucidated on the basis of spectroscopic data (UV, IR, HR-ESI-MS, 1D and 2D NMR, and CD). In the in vitro assay, compounds 1, 5, 6, 9, and 10 exhibited NO inhibitory effects of LPS-induced BV-2 cells with IC50 values in the range of 10.4 μM to 27.2 μM.

journal_name

J Asian Nat Prod Res

authors

Gao P,Wang L,Zhao L,Zhang C,Zeng KW,Zhao MB,Zhang QY,Jiang Y,Tu PF,Guo XY

doi

10.1080/10286020.2019.1620213

subject

Has Abstract

pub_date

2020-08-01 00:00:00

pages

716-723

issue

8

eissn

1028-6020

issn

1477-2213

journal_volume

22

pub_type

杂志文章
  • Resolution and chiral recognition of muscone as well as actions on neural system.

    abstract::In this letter, (R)-muscone and (S)-muscone were prepared by optical resolution of dl-muscone using N,N'-dibenzyl-l-tartaramide or N,N'-dibenzyl-d-tartaramide, according to the method reported by Kunihiko Takabe. But we separated the diastereomers using EtOH instead of MeOH in the recrystallization step to get the goa...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.996141

    authors: Meng Y,Xiao Q,Bai JY,Xiao X,Zhang S,Zhu XY,Cheng GF,Yin DL

    更新日期:2014-12-01 00:00:00

  • Siraitic acid F, a new nor-cucurbitacin with novel skeleton, from the roots of Siraitia grosvenorii.

    abstract::A new cucurbitane triterpene, siraitic acid F (1), has been isolated from the roots of Siraitia grosvenorii (Swingle) C. Jeffrey, and its structure has been elucidated as 29-nor-4,24-diene-3,11-dioxo-19-hydroxy-6,19-cyclocucurbitane-26-oic acid on the basis of spectroscopic evidences, including a series of 2D NMR anal...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020310001609010

    authors: Si JY,Chen DH,Tu GZ

    更新日期:2005-02-01 00:00:00

  • Synthesis, anticancer, and antibacterial activities of piplartine derivatives on cell cycle regulation and growth inhibition.

    abstract::A series of piplartine derivatives were synthesized via Baylis-Hillman reaction and evaluated for anticancer and antibacterial activities. The cytotoxicity of these compounds was examined in two different human tumor cell lines, IMR-32 and HeLa. The antibacterial activity was examined in Staphylococcus aureus and Pseu...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.769965

    authors: Kumar JU,Shankaraiah G,Kumar RS,Pitke VV,Rao GT,Poornima B,Babu KS,Sreedhar AS

    更新日期:2013-01-01 00:00:00

  • Manuifolin Q, an unusual 4-aryl-substituted isoflavan from Maackia tenuifolia.

    abstract::Manuifolin Q (1), an unusual 4-aryl-substituted isoflavan, was isolated from the roots of Maackia tenuifolia. Its absolute configuration was determined as (3R,4R)-3,4-trans-7,2'-dihydroxy-4'-methoxy-4-[(2,4-dihydroxy-5-(1,1-dimethyl-2-propenyl)]-phenyl-isoflavan, on the basis of spectroscopic analysis. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/1028602031000119817

    authors: Zeng JF,Tan CH,Zhu DY

    更新日期:2004-03-01 00:00:00

  • Seeking new anti-cancer agents from autophagy-regulating natural products.

    abstract::Natural products are an important original source of many widely used drugs, including anti-cancer drugs. Early research efforts for seeking anti-cancer therapy from the natural products are mainly focused on the compounds with cytotoxicity capability. The good examples include vinblastine, vincristine, the camptothec...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章,评审

    doi:10.1080/10286020.2017.1304385

    authors: Hua F,Shang S,Hu ZW

    更新日期:2017-04-01 00:00:00

  • Two new indole alkaloids from Nauclea officinalis.

    abstract::Two new indole alkaloids, naucleactonin A and B, along with two known compounds, naucleficine and nauclefidine, were isolated from the bark and wood of Naucleaofficinalis, which has been used as an anti-inflammatory and anti-bacterial agent in folk medicine. Their chemical structures were elucidated by the spectral da...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020500246741

    authors: Xuan WD,Chen HS,Du JL,Liang S,Li TZ,Cai DG

    更新日期:2006-12-01 00:00:00

  • Constituents from the roots of Heracleum rapula Franch.

    abstract::A new coumarin glucoside, 8-hydroxy-5-O-beta-D-glucosylpsoralen, along with 17 known coumarins and one steroid, was isolated from the roots of Heracleum rapula Franch. Four coumarin glucosides, including the new one, were obtained from the water-soluble fraction. The other coumarins isolated from the ethyl acetate-fra...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020290019677

    authors: Niu XM,Li SH,Jiang B,Zhao QS,Sun HD

    更新日期:2002-03-01 00:00:00

  • Cytotoxic triterpenes from the acid hydrolyzate of Gynostemma pentaphyllum saponins.

    abstract::One new dammarane-type triterpene, gypsapogenin A (1), was isolated from the acid hydrolyzate of total saponins from Gynostemma pentaphyllum (Thunb.) Makino, together with two known compounds, (20S,24S)-3β,20,21β,23β,25-pentahydroxy-21,24-cyclodammarane (2) and (23S)-3β-hydroxydammar-20,24-dien-21-oic acid 21,23-lacto...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1322070

    authors: Shi L,Tan DH,Yan TC,Jiang DH,Hou MX

    更新日期:2018-02-01 00:00:00

  • A new acylated flavonoid glycoside from the flowers of Camellia nitidissima and its effect on the induction of apoptosis in human lymphoma U937 cells.

    abstract::From the EtOH extract of the flowers of Camellia nitidissima Chi, a new acylated flavonoid glycoside, quercetin 7-O-(6"-O-E-caffeoyl)-β-D-glucopyranoside (1), has been isolated, together with three known flavonoids: quercetin (2), quercetin 3-O-β-D-glucopyranoside (3), and quercetin 7-O-β-D-glucopyranoside (4). Their ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.691475

    authors: Peng X,Yu DY,Feng BM,Wang YQ,Shi LY

    更新日期:2012-01-01 00:00:00

  • Anti-hyperglycemic effect of 11-hydroxypalmatine, a palmatine derivative from Stephania glabra tubers.

    abstract::A palmatine derivative, named 11-hydroxypalmatine (4), has been isolated from the tubers of Stephania glabra, together with three known alkaloids, palmatine (1), dehydrocorydalmine (2), and stepharanine (3). The structures of the compounds were elucidated by means of spectroscopic analysis including 2D NMR experiments...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020903117325

    authors: Semwal DK,Rawat U,Semwal R,Singh R,Singh GJ

    更新日期:2010-02-01 00:00:00

  • A novel oxybis cresol verticilatin with highly varying degrees of biological activities from the insect pathogenic fungus Paecilomyces verticillatus.

    abstract::A novel oxybis cresol compound named verticilatin (1), together with two known compounds, 5-methylresorcinol (2) and 2,4-dihydroxy-3,6-dimethylbenzaldehyde (3), was isolated from cultures of the insect pathogenic fungi Paecilomyces verticillatus. The structures of compounds were determined by extensive spectroscopic a...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.959438

    authors: Wei PY,Li L,Yang CG,Luo DQ,Zheng ZH,Lu XH,Shi BZ

    更新日期:2014-12-01 00:00:00

  • Two new illudin type sesquiterpenoids from cultures of Phellinus tuberculosus and Laetiporus sulphureus.

    abstract::Chemical investigation on the cultures of Phellinus tuberculosus and Laetiporus sulphureus lead to the isolation of two new illudin-type sesquiterpenoids (phellinuin J and sulphureuine A). Their structures were elucidated by 1D, 2D NMR and MS spectroscopic data. These compounds were purposely evaluated for their cytot...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2015.1040774

    authors: He JB,Tao J,Miao XS,Feng YP,Bu W,Dong ZJ,Li ZH,Feng T,Liu JK

    更新日期:2015-01-01 00:00:00

  • Rhein lysinate decreases the generation of β-amyloid in the brain tissues of Alzheimer's disease model mice by inhibiting inflammatory response and oxidative stress.

    abstract::The protective effect of rhein lysinate (RHL) on Alzheimer's disease (AD) was explored in senescence-accelerated mouse prone-8 (SAMP8) mice. SAMP8 mice without treatment were used as the AD-positive control, and senescence-accelerated-resistant mice were used as the AD-negative control. In this study, 4-month-old male...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.800972

    authors: Liu J,Hu G,Xu R,Qiao Y,Wu HP,Ding X,Duan P,Tu P,Lin YJ

    更新日期:2013-07-01 00:00:00

  • An efficient enantioselective synthesis of (S)-α-methyl-serine methyl ester hydrochloride via asymmetrically catalyzed amination.

    abstract::We present the synthesis of enantiomerically pure (S)-α-methyl-serine methyl ester hydrochloride from 2-methyl-3-((4-(trifluoromethyl)benzyl)oxy)propanal and di-p-chlorobenzyl azodicarboxylate via asymmetrically catalyzed amination with naphthylalanine derivative catalyst. The application of the organocatalyst of D-3-...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2019.1634058

    authors: Xiao Q,Tang YF,Xie P

    更新日期:2020-01-01 00:00:00

  • Crassicaulisine, a new sulphonoglycolipid from the red alga Chondria crassicaulis Harv.

    abstract::A new sulphonoglycolipid, crassicaulisine, has been isolated from the red alga Chondria crassicaulis Harv.. Four known compounds were also found from the title plant. The structure of the new compound was elucidated on the basis of chemical reactions and spectroscopic analysis. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020290024004

    authors: Shao ZY,Cai JN,Ye QZ,Guo YW

    更新日期:2002-09-01 00:00:00

  • Four new oleanane type saponins from Morina nepalensis var. alba.

    abstract::Four new oleanane type saponins, monepalosides G-J (1-4), were isolated from the water-soluble part of the whole plant of Morina nepalensis var. alba Hand-Mazz. On the basis of chemical and spectroscopic evidence, their structures were determined as 3-O-alpha-L-arabinopyranosyl-(1 --> 3)-alpha-L-arabinopyranosyl olean...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020290028965

    authors: Teng RW,Xie HY,Liu XK,Wang DZ,Yang CR

    更新日期:2003-06-01 00:00:00

  • Chemical constituents from the stem barks of Garcinia multiflora.

    abstract::Investigation of the constituents from the stem barks of Garcinia multiflora has yielded two new compounds, multiflorabiphenyl A (1) and 24-p-E-coumaroyl-tetracosanyl (E)-ferulate (2), along with 10 known compounds, friedelin (3), friedelan-3β-ol (4), α,β-amyrin (5), rheediachromenoxanthone (6), 1,7-dihydroxyxanthone ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.819854

    authors: Jing WY,Jiang C,Ji F,Hua HM,Li ZL

    更新日期:2013-11-01 00:00:00

  • Total synthesis and cyclization strategy of samoamide A, a cytotoxic cyclic octapeptide rich in proline and phenlalanine isolated from marine cyanobacterium.

    abstract::Samoamide A is a cyclic octapeptide rich in proline and phenylalanine residues isolated from an American Samoa marine cyanobacterium, which exhibits potent activity against H460 human non-small-cell lung cancer cells (IC50 of 1.1 μM). The first total synthesis of samoamide A was achieved by employing a strategy of a s...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2018.1450391

    authors: Chang Q,Li YL,Zhao X

    更新日期:2019-02-01 00:00:00

  • Two eudesmane sesquiterpenes from Laggera pterodonta.

    abstract::The phytochemical study of the aerial parts of Laggera pterodonta afforded two new eudesmane sesquiterpenes, 3alpha,4beta,11-trihydroxyenantioeudesmane (pterodontriol E) (1) and 4beta,8beta,11-trihydroxyenantioeudesmane (pterodontriol F) (2), along with seven known compounds. Their structures were elucidated on the ba...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020500034964

    authors: Liu YB,Jia W,Gao WY,Zhao AH,Zhang YW,Takaishi Y,Duan HQ

    更新日期:2006-06-01 00:00:00

  • New polyoxygenated cyclohexene and polyoxygenated seco-cyclohexene from Uvaria boniana.

    abstract::A new polyoxygenated cyclohexene bonianol A (1) and another new polyoxygenated seco-cyclohexene bonianol B (2) were isolated from the leaves of Uvaria boniana, and their structures were established on the basis of spectroscopic methods including IR, HR-ESI-MS, 1D, and 2D NMR. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.743529

    authors: Chen Z,Liu YL,Xu QM,Liu JY,Duan HQ,Yang SL

    更新日期:2013-01-01 00:00:00

  • Triterpene saponins from the leaves of Ilex kudingcha.

    abstract::Three new triterpene saponins, ilekudinosides T-V (1-3), along with six known saponins were isolated from the 70% ethanolic extract of the leaves of Ilex kudingcha. The new saponins were characterized as 3-O-beta-d-glucopyranosyl-(1 --> 3)-[alpha-l-rhamnopyranosyl-(1 --> 2)]-alpha-l-arabinopyranosyl-3beta,19alpha-dihy...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020902937491

    authors: Tang L,Jiang Y,Tian XM,Zhou SX,Tu PF

    更新日期:2009-06-01 00:00:00

  • Chemical constituents of Nouelia insignis Franch.

    abstract::Two new diterpenes and ent-15alpha-hydroxykaur-16-en-19-oic acid 11,12-acetonide (3), together with 23 known compounds were isolated from the dried aerial parts of Nouelia insignis Franch. The structures of new compounds were determined to be ent-14beta,15alpha-dihydroxykaur-16-en-19-oic acid (1), ent-14beta-hydroxy-1...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020701189500

    authors: Hu XY,Luo YG,Chen XZ,Zhou L,Zhang GL

    更新日期:2008-01-01 00:00:00

  • Four lanostane-type triterpenes from the fruiting bodies of mushroom Laetiporus sulphureus var. miniatus.

    abstract::Two new 3,4-seco-lanostane-type triterpenes, named as 15α-hydroxy-3,4-seco-lanosta-4(28),8,24-triene-3,21-dioic acid (1), 5α-hydroxy-3,4-seco-lanosta-4(28),8,24-triene-3,21-dioic acid 3-methyl ester (2), and one new lanostane triterpene 15α-acetoxylhydroxytrametenolic acid (3) together with a known one versisponic aci...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2015.1027694

    authors: Yin X,Li ZH,Li Y,Feng T,Liu JK

    更新日期:2015-01-01 00:00:00

  • A new prenylated coumarin diglycoside with insulin-release promoting activity from Clausena dunniana.

    abstract::A new prenylated coumarin diglycoside, 6-prenylcoumarin-7-O-β-D-apiofuranosyl-(1→6)-β-D-glucopyranoside (1) and five known flavonoid glycosides (2-6) were isolated from the leaves and stems of Clausena dunniana. The structures of these isolates were elucidated based on comprehensive MS, UV, IR, and NMR spectroscopic d...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2020.1810671

    authors: Cao NK,Zhu SS,Chen YM,Ma XL,Zhao MB,Li J,Tu PF,Jiang Y

    更新日期:2020-08-30 00:00:00

  • New phenolic glycosides from the seeds of Cucurbita moschata.

    abstract::Two new phenolic glycosides were isolated from the seeds of Cucurbita moschata. Their structures were elucidated as (2-hydroxy)phenylcarbinyl 5-O-benzoyl-beta-D-apiofuranosyl(1-->2)-beta-D-glucopyranoside (1) and 4-beta-D-(glucopyranosyl hydroxymethyl)phenyl 5-O-benzoyl-beta-D-apiofuranosyl(1-->2)-beta-D-glucopyranosi...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020902942376

    authors: Li FS,Dou DQ,Xu L,Chi XF,Kang TG,Kuang HX

    更新日期:2009-07-01 00:00:00

  • Four new minor taxanes from cell cultures of Taxus chinensis.

    abstract::Four new minor taxanes (1-4) have been isolated from Ts-19 cell cultures of Taxus chinensis together with five known taxanes (5-9) by silica gel chromatography combined with semi-preparative HPLC chromatography. On the basis of the analyses of the chemical and spectroscopic (IR, MS, 1D, and 2D NMR) data, the structure...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020902882143

    authors: Xie D,Jia HT,Zhang Y,Zou JH,Yin DL,Chen XG,Yan YN,Dai JG

    更新日期:2009-06-01 00:00:00

  • Four new triterpenoid saponins from Ardisia gigantifolia Stapf. and their cytotoxic activity.

    abstract::Four new oleanane-type triterpenoid saponins, cyclamiretin A 3beta-O-alpha-L-rhamnopyranosyl-(1 --> 3)-[beta-D-xylopyranosyl-(1 --> 2)]-beta-D-glucopyranosyl-(1 --> 4)-[beta-D-glucopyranosyl-(1 --> 2)]-alpha-L-arabinopyranoside (1), cyclamiretin A 3beta-O-alpha-L-rhamnopyranosyl-(1 --> 3)-[beta-D-glucopyranosyl-(1 -->...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020802144719

    authors: Wen P,Zhang XM,Yang Z,Wang NL,Yao XS

    更新日期:2008-09-01 00:00:00

  • Alkaloids with antioxidant activities from Aconitum handelianum.

    abstract::A new C20-diterpenoid alkaloid handelidine (1) and twenty-seven known alkaloids (2-28) were isolated from the roots of Aconitum handelianum. Their structures were established on the basis of extensive spectroscopic analyses. The study indicated that denudatine-type C20-diterpenoid alkaloids with vicinal-triol system a...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2015.1114473

    authors: Yin TP,Cai L,Xing Y,Yu J,Li XJ,Mei RF,Ding ZT

    更新日期:2016-06-01 00:00:00

  • Isoprenylated phenolic compounds with tyrosinase inhibition from Morus nigra.

    abstract::A new isoprenylated sanggenon-type flavanone, nigrasin K (1), together with three known analogs (2-4) and five known Diels-Alder adducts (5-9), were isolated from the twigs of Morus nigra. Their structures were elucidated by spectroscopic methods. Sanggenon M (2), chalcomoracin (5), sorocein H (6), kuwanon J (7), sang...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2017.1350653

    authors: Hu X,Yu MH,Yan GR,Wang HY,Hou AJ,Lei C

    更新日期:2018-05-01 00:00:00

  • Four new C19-diterpenoid alkaloids from Aconitum hemsleyanum var. circinatum.

    abstract::Four new C19-diterpenoid alkaloids, hemaconitines A-D (1-4), were isolated from the roots of Aconitum hemsleyanum var. circinatum. Their structures were elucidated as 19R-hydroxyl-secoyunnaconitine (1), (3R)-hydroxyl-liwaconitine (2), 14-anisoyl-leucanthumsine E (3), and 19R -acetonyl-8-O-methyltalatisamine (4) by ext...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2018.1500555

    authors: He D,Liu WY,Xiong J,Xu JJ,Shen Y

    更新日期:2019-09-01 00:00:00