Three new compounds from Dictamnus dasycarpus and their anti-inflammatory activities.

Abstract:

:Three new compounds (1-3), named dasycarine G (1), dasycarether (2), and dasycarester (3), along with seven known compounds (4-10) obtained from the genus Dictamnus for the first time, were isolated from the root bark of Dictamnus dasycarpus. Their structures were elucidated on the basis of spectroscopic data (UV, IR, HR-ESI-MS, 1D and 2D NMR, and CD). In the in vitro assay, compounds 1, 5, 6, 9, and 10 exhibited NO inhibitory effects of LPS-induced BV-2 cells with IC50 values in the range of 10.4 μM to 27.2 μM.

journal_name

J Asian Nat Prod Res

authors

Gao P,Wang L,Zhao L,Zhang C,Zeng KW,Zhao MB,Zhang QY,Jiang Y,Tu PF,Guo XY

doi

10.1080/10286020.2019.1620213

subject

Has Abstract

pub_date

2020-08-01 00:00:00

pages

716-723

issue

8

eissn

1028-6020

issn

1477-2213

journal_volume

22

pub_type

杂志文章
  • New steroidal glycosides from Hosta plantaginea (Lam.) Aschers.

    abstract::Four new furostanol glycosides were isolated from the flowers of Hosta plantaginea (Lam.) Aschers. On the basis of spectroscopic methods including 1D and 2D NMR experiments, their structures were elucidated as 26-O-β-d-glucopyranosyl-(25R)-22-O-methyl-5α-furostan-2α,3β,22ξ,26-tetrol 3-O-α-l-rhamnopyranosyl-(1 → 4)-O-β...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.998652

    authors: Li XJ,Wang L,Xue PF,Xie HX,Wei H,Wang J

    更新日期:2015-01-01 00:00:00

  • Influence of sulfation on anti-myocardial ischemic activity of Ophiopogon japonicus polysaccharide.

    abstract::Ophiopogon japonicus polysaccharide (FOJ-5) from Radix ophiopogonis has shown anti-myocardial ischemic action in vitro and in vivo in our previous studies. In order to clarify the influence of chemical modifications on the action, a series of sulfated FOJ-5 (FOJ-5-S) with different substitution degrees were prepared a...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020902727363

    authors: Zheng Q,Feng Y,Xu DS,Lin X,Chen YZ

    更新日期:2009-01-01 00:00:00

  • (+)-Cyclopenol, a new naturally occurring 7-membered 2,5-dioxopiperazine alkaloid from the fungus Penicillium sclerotiorum endogenous with the Chinese mangrove Bruguiera gymnorrhiza.

    abstract::One new naturally occurring 7-membered 2,5-dioxopiperazine alkaloid named (+)-cyclopenol (1), along with nine known compounds including viridicatol (2), 3-(dimethylaminomethyl)-1-(1,1-dimethyl-2-propenyl)indole (3), anacine (4), aurantiomide C (5), viridicatin (6), 3-O-methylviridicatin (7), verrucosidin (8), ergoster...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.911290

    authors: Li J,Wang J,Jiang CS,Li G,Guo YW

    更新日期:2014-01-01 00:00:00

  • A new prenylated xanthone from the branches of Calophyllum inophyllum.

    abstract::The investigation of chemical constituents from the branches of Calophyllum inophyllum Linn led to the isolation of a new prenylated xanthone, named caloxanthone Q (1), together with three known compounds, 2-deprenylrheediaxanthone B (2), jacareubin (3), and 6-deoxyjacareubin (4). Their structures were completely eluc...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2010.550884

    authors: Wei DJ,Mei WL,Zhong HM,Zeng YB,Wu XD,Dai HF

    更新日期:2011-03-01 00:00:00

  • Two new acylgluconic acids from the nearly ripe fruits of Evodia rutaecarpa.

    abstract::Two new acylgluconic acids, trans-feruloylgluconic acid (1) and trans-caffeoylgluconic acid (2), together with three known compounds, myo-inositol (3), phthalic acid dibutyl ester (4), and wuzhuyuamide-I (5), were isolated from the water soluble part of the dried nearly ripe fruits of Evodia rutaecarpa (Juss.) Benth. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020802031080

    authors: Zhao MY,Yang XW

    更新日期:2008-07-01 00:00:00

  • New iridoids from Pedicularis artselaeri.

    abstract::Three new iridoids, named artselaenin I, II and III, were isolated from the whole plants of Pedicularis artselaeri, along with 11 known compounds, 8-epiloganic acid, 7-deoxy-8-epiloganic acid, plantarenaloside, mussaenoside, lariciresinol-4-O-beta-D-glucoside, lariciresinol-4'-O-beta-D-glucoside, alaschaniosideA, cirt...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286029808039851

    authors: Su BN,Zhai JJ,Jia ZJ

    更新日期:1998-01-01 00:00:00

  • Effect of corchorusin-D, a saikosaponin like compound, on B16F10 melanoma cells (in vitro and in vivo).

    abstract::Corchorusin-D (COR-D), isolated from Corchorus acutangulus, was reported to induce apoptosis in leukemic cells. However, no studies concerning its activity on melanoma cells have been reported. We have evaluated its in vitro anti-cancer activity on melanoma cells (B16F10, SK-MEL-28, and A375). The results demonstrate ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.837451

    authors: Mallick S,Pal BC,Kumar D,Chatterjee N,Das S,Saha KD

    更新日期:2013-11-01 00:00:00

  • Flavonoid glycosides from Thalictrum przewalskii.

    abstract::A new flavonoid glycoside, 5,7-dihydroxy-4'-methoxyflavone-7-O-[6-O-(4-O-acetyl-alpha-L-rhamnosyl)-3-O-beta-D-glucosyl]-6-O-acetyl-beta-D-glucoside and three known flavonoid glycosides, 5,7-dihydroxy-4-methoxyflavone-7-0-[6-0-(4-0-acetyl-alpha-L-rhamnosyl)]-beta-D-glucoside, 3,5,7, 4'-tetrahydroxyflavonol-3-O-beta-D-g...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286029908039878

    authors: Yu SC,Wu QL,Wang LW,Yang JS,Xiao PG

    更新日期:1999-01-01 00:00:00

  • Venuloxanthone, a new pyranoxanthone from the stem bark of Calophyllum venulosum.

    abstract::A new pyranoxanthone, venuloxanthone (1), was isolated from the stem bark of Calophyllum venulosum, together with three other xanthones, tovopyrifolin C (2), ananixanthone (3) and caloxanthone I (4), along with two common triterpenes, friedelin (5) and lupeol (6). The structures of these compounds were identified usin...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2015.1047353

    authors: Bin Ismail AA,Ee GC,Bin Daud S,Teh SS,Hashim NM,Awang K

    更新日期:2015-01-01 00:00:00

  • Synthesis and cytotoxic activity of two steroids: icogenin aglycone analogs.

    abstract::During the process of icogenin analog research, we obtained two cytotoxic steroids: compound 4 and compound 6 casually. Their in vitro antitumor activities were tested by the standard MTT assay. The results disclosed that compound 4 (IC50 = 3.65-6.90 μM) showed potential antitumor activities against HELA, KB cell line...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2016.1228633

    authors: Guan YY,Li SZ,Lei PS

    更新日期:2017-05-01 00:00:00

  • C₁₄-polyacetylene glucosides from Codonopsis pilosula.

    abstract::Seven new C14-polyacetylene glucosides codonopilodiynosides A-G (1-7) were isolated from an aqueous extract of the Codonopsis pilosula roots. Their structures were determined by spectroscopic and chemical methods as (-)-(5S,6E,12E)-tetradeca-6,12-dien-8,10-diyn-1,5,14-triol 5-O-β-D-glucopyranoside (1), (-)-(5S,6E,12E)...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2015.1041932

    authors: Jiang YP,Liu YF,Guo QL,Jiang ZB,Xu CB,Zhu CG,Yang YC,Lin S,Shi JG

    更新日期:2015-01-01 00:00:00

  • New tetraterpenoid from the soft coral Sarcophyton tortuosum.

    abstract::A novel tetraterpenoid named methyl tortuoate C (1) has been isolated from the soft coral Sarcophyton tortuosum Tix.-Dur. The structure of 1 was determined on the basis of spectroscopic methods. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020600604344

    authors: Lan WJ,Li HJ,Yan SJ,Su JY,Zeng LM

    更新日期:2007-04-01 00:00:00

  • New phenethyl alcohol glycosides from Stachys parviflora.

    abstract::Phytochemical investigations of the whole plant of Stachys parviflora (Lamiaceae) resulted in the isolation of two new phenethyl alcohol glycosides. The structures of the new compounds named parviflorosides A and B were established as 2-(3,4-dihydroxyphenyl)-ethyl-O-alpha-L-rhamnopyranosyl-(1 --> 2)-4-O-E-caffeoyl-bet...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020500478708

    authors: Ahmad VU,Arshad S,Bader S,Ahmed A,Iqbal S,Tareen RB

    更新日期:2006-01-01 00:00:00

  • Synthesis, anticancer, and antibacterial activities of piplartine derivatives on cell cycle regulation and growth inhibition.

    abstract::A series of piplartine derivatives were synthesized via Baylis-Hillman reaction and evaluated for anticancer and antibacterial activities. The cytotoxicity of these compounds was examined in two different human tumor cell lines, IMR-32 and HeLa. The antibacterial activity was examined in Staphylococcus aureus and Pseu...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.769965

    authors: Kumar JU,Shankaraiah G,Kumar RS,Pitke VV,Rao GT,Poornima B,Babu KS,Sreedhar AS

    更新日期:2013-01-01 00:00:00

  • Two new indole alkaloids from Nauclea officinalis.

    abstract::Two new indole alkaloids, naucleactonin A and B, along with two known compounds, naucleficine and nauclefidine, were isolated from the bark and wood of Naucleaofficinalis, which has been used as an anti-inflammatory and anti-bacterial agent in folk medicine. Their chemical structures were elucidated by the spectral da...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020500246741

    authors: Xuan WD,Chen HS,Du JL,Liang S,Li TZ,Cai DG

    更新日期:2006-12-01 00:00:00

  • Four new koumine metabolites in rat liver microsomes.

    abstract::Four new metabolites M-1 [1,2,18,19-tetradehydro-4-demethyl-3,17-epoxy-7,20(2H,19H)-cyclovobasan], M-2 [1,2,4,21,18,19-hexadehydro-4-demethyl-3,17-epoxy-7,20(2H,19H)-cyclovobasan], M-3 [1,2,18,19-tetradehydro-4-demethyl-4-formaldehyde-3,17-epoxy-7,20(2H,19H)-cyclovobasan], and M-4 [1,2,4,21,18,19-hexadehydro-4-demethy...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.742511

    authors: Zhang L,Du L,Lv WW,Zhao QC,Hua W,An Y,Guo T,Wu LJ

    更新日期:2013-01-01 00:00:00

  • Alkaloids with antioxidant activities from Aconitum handelianum.

    abstract::A new C20-diterpenoid alkaloid handelidine (1) and twenty-seven known alkaloids (2-28) were isolated from the roots of Aconitum handelianum. Their structures were established on the basis of extensive spectroscopic analyses. The study indicated that denudatine-type C20-diterpenoid alkaloids with vicinal-triol system a...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2015.1114473

    authors: Yin TP,Cai L,Xing Y,Yu J,Li XJ,Mei RF,Ding ZT

    更新日期:2016-06-01 00:00:00

  • Four new triterpenes from the endemic relict shrub Tetraena mongolica.

    abstract::A chemical investigation of the endemic relict shrub Tetraena mongolica led to the isolation of four new triterpenes: 11α,12α:13β,28-diepoxyoleanane-3β-yl trans-caffeate (1), 3β-hydroxy-11α,12α-epoxyoleanane-28-al (2), olean-11-en-28-al-3β-yl trans-caffeate (3), and 28-acetoxy-olean-12-en-3β-yl trans-caffeate (4). The...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.699525

    authors: Tang SA,Ding LL,Zhai HY,Qin N,Duan HQ

    更新日期:2012-01-01 00:00:00

  • Two new lignans from Mentha spicata L.

    abstract::Two new lignans named spicatolignan A (1) and spicatolignan B (2) have been isolated from the whole herbs of Mentha spicata L. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020500384641

    authors: Zheng J,Chen GT,Gao HY,Wu B,Wu LJ

    更新日期:2007-04-01 00:00:00

  • New lignans from Urticae Fissae Herba.

    abstract::Two new lignans named neourticol A (1) and neourticol B (2), together with seven known compounds (3-9), were isolated from Urticae Fissae Herba, a folk medicine for rheumatism arthritis in China. The active evaluation results showed that 1 and 2 possessed the potent anti-complement and anti-inflammatory activities. ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2018.1457652

    authors: Wang MY,Zhang Y,Zhang H,Feng XR,Li XB

    更新日期:2019-06-01 00:00:00

  • Three new sesquiterpenoids from cultures of the basidiomycete Conocybe siliginea.

    abstract::Three new sesquiterpenoids (1-3), along with four known compounds (4-7), were isolated from cultures of the fungus Conocybe siliginea. The structures of new compounds were elucidated using spectroscopic methods. The known compounds were identified by comparing their spectroscopic data with those reported in the litera...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2014.939072

    authors: Yang XY,Li ZH,Dong ZJ,Feng T,Liu JK

    更新日期:2015-01-01 00:00:00

  • A new hTopo I isomerase inhibitor produced by a mangrove endophytic fungus no. 2240.

    abstract::A new hTopo I isomerase inhibitor, (+)-3,3',7,7',8,8'-hexahydroxy-5,5'-dimethylbianthraquinone (2240A), was isolated from the mangrove endophytic fungus no. 2240 collected from an estuarine mangrove at the South China Sea coast. Its structure was elucidated by spectral analyses including two-dimensional NMR, HR-EI-MS,...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020802133167

    authors: Tan N,Cai XL,Wang SY,Pan JH,Tao YW,She ZG,Zhou SN,Lin YC,Vrijmoed LL

    更新日期:2008-07-01 00:00:00

  • Trollioside, a new compound from the flowers of Trollius chinensis.

    abstract::A new compound, named trollioside, together with nine known compounds, proglobeflowery acid, isoswertisin, isoswertiajaponin, cirsimaritin, veratric acid, vitexin, orientin, beta-sitosterol and daucosterol, were isolated from the ethanol extract of the dried flowers of Trollius chinensis Bunge. The isolation and struc...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/1028602031000147393

    authors: Wang RF,Yang XW,Ma CM,Liu HY,Shang MY,Zhang QY,Cai SQ,Park JH

    更新日期:2004-06-01 00:00:00

  • Structural revision of methyl tortuoate D, a bis-cembranoid from Hainan Sarcophyton tortuosum and its absolute stereochemistry.

    abstract::Methyl tortuoate D (1), together with five other known related bis-cembranoids, was isolated from Hainan soft coral Sarcophyton tortuosum. The structure of methyl tortuoate D (1a), firstly isolated and reported by Li et al. from the title organism, was corrected as 1 by an extensive analysis of its one-dimensional and...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2013.787988

    authors: Li YF,He LL,Liu HL,Liang LF,Zhang HB,Guo YW

    更新日期:2013-01-01 00:00:00

  • The synthesis and biological evaluation of 10-O-dialkylaminoethyl ginkgolide B as platelet-activating factor antagonist.

    abstract::Four nitrogen-containing derivatives of ginkgolide B were synthesized to improve the physical-chemical properties and bioavailability of ginkgolide B. The reaction was accomplished with the nitrogen atom as neighboring group participating in the replacement reaction. All of the four compounds were proved to have excel...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020802240376

    authors: Guo CJ,Ren Y,Qin YL,Zhang Q

    更新日期:2008-09-01 00:00:00

  • New phenolic glycosides from Polygonum cuspidatum.

    abstract::Two new isobenzofuranone derivatives, polyphthaliside A (1) and polyphthaliside B (2), and a new isocoumarin derivative, polyisocoumarin (3), were isolated from Polygonum cuspidatum. Their structures were elucidated by detailed spectroscopic analysis and chemical methods. The cytotoxicity activity and PTP1B inhibitory...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2019.1646730

    authors: Jiang JS,Li FS,Feng ZM,Yang YN,Zhang PC

    更新日期:2020-01-01 00:00:00

  • Suppression of IL-8 gene transcription by resveratrol in phorbol ester treated human monocytic cells.

    abstract::Resveratrol (3,4',5-trihydroxy-trans-silbene), a natural phytoalexin found in grapes and other food products, has promising anti-inflammatory and anticancer effects. To observe the modulation of interleukin-8 (IL-8) production in human monocytic cells by resveratrol and explore its mechanism at the gene transcription ...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/1028602031000066852

    authors: Shen F,Chen SJ,Dong XJ,Zhong H,Li YT,Cheng GF

    更新日期:2003-06-01 00:00:00

  • Two new saponins from Thalictrum fortunei.

    abstract::Two new cycloartane glycosides were isolated from the aerial parts of Thalictrum fortunei (Ranunculaceae). The chemical structures of these compounds were elucidated as 3-O-β-D-glucopyranosyl (1 → 4)-β-d-fucopyranosyl-(22S,24Z)-cycloart-24-en-3β,22,26,30-tetraol 26-O-β-D-glucopyranoside and 3-O-β-D-glucopyranosyl (1 →...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2011.653684

    authors: Zhang XT,Ma SW,Jiao HY,Zhang QW

    更新日期:2012-01-01 00:00:00

  • A new diimide derivative from the co-culture broth of two mangrove fungi (strain no. E33 and K38).

    abstract::A new diimide derivative, named (-)-byssochlamic acid bisdiimide (1), was isolated from the mixed broth of two mangrove fungi (strain no. K38 and E33) from the South China sea coast. The structure of 1 was determined by comprehensive spectroscopic methods, including 1D and 2D NMR (COSY, HMQC, and HMBC) and semi-synthe...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2010.497757

    authors: Li CY,Ding WJ,Shao CL,She ZG,Lin YC

    更新日期:2010-09-01 00:00:00

  • Two new compounds from the metabolites of a marine-derived actinomycete Streptomyces cavourensis YY01-17.

    abstract::Our current marine natural product program investigated the second metabolites of an actinomycete Streptomyces cavourensis YY01-17 originating from the Antarctic ecological niche to discover potential antitumor chemical entities. Two new compounds, along with a known compound, were isolated from the ethyl acetate extr...

    journal_title:Journal of Asian natural products research

    pub_type: 杂志文章

    doi:10.1080/10286020.2012.762764

    authors: Su SS,Tian L,Chen G,Li ZQ,Xu WF,Pei YH

    更新日期:2013-01-01 00:00:00