Comprehensive and Systematic Analysis of Gene Expression Patterns Associated with Body Mass Index.

abstract：:In this article we show that diffraction segregates the polarization singularities according to their handedness. Polarization singularities are superpositions of left and right handed circular polarization vortex states. In the superposition, the component states possess different orbital angular momenta depending on...

journal_title：Scientific reports

authors： Deepa S,B S BR,Senthilkumaran P

更新日期：2019-08-28 00:00:00

abstract：:Recent studies have shown inconsistent results regarding the value of desmoteplase for treating acute ischemic stroke (AIS) when administered within an extended time window. We performed a meta-analysis to explore the value of desmoteplase in AIS treatment. The MEDLINE, EMBASE, and Cochrane Library databases were sear...

journal_title：Scientific reports

authors： Shi L,Liang F,Li Y,Shao A,Zhou K,Yu J,Zhang J

更新日期：2016-09-27 00:00:00

abstract：:The Paraná delta, growing at a rate of c. 2 km(2) yr(-1) since 6,000 yrs, is one of the most complete records of the Late Holocene in southern South America. The evolution of this 17,400 km(2) delta enclosed in Plata estuary, can be tracked by a series of 343 successive coastal-ridges showing a c.11 years period, in c...

journal_title：Scientific reports

authors： Milana JP,Kröhling D

更新日期：2015-08-06 00:00:00

abstract：:The objective was to establish and evaluate a method for manufacture of custom trays for edentulous jaws using computer aided design and fused deposition modeling (FDM) technologies. A digital method for design the custom trays for edentulous jaws was established. The tissue surface data of ten standard mandibular ede...

journal_title：Scientific reports

authors： Chen H,Yang X,Chen L,Wang Y,Sun Y

更新日期：2016-01-14 00:00:00

abstract：:A fundamental task in cancer research aims at the identification of new pharmacological therapies that can affect tumor growth. Differentiation therapy might exploit this function not only for hematological diseases, such as acute promyelocytic leukemia (APML) but also for epithelial tumors, including lung cancer. Her...

journal_title：Scientific reports

authors： Zito G,Naselli F,Saieva L,Raimondo S,Calabrese G,Guzzardo C,Forte S,Rolfo C,Parenti R,Alessandro R

更新日期：2017-07-06 00:00:00

abstract：:Horizontal gene transfer (HGT) drives the evolution of recipient organism particularly if it provides a novel function which enhances the fitness or its adaption to the environment. Virus-host co-evolution is attractive for studying co-evolutionary processes, since viruses strictly replicate inside of the host cells a...

journal_title：Scientific reports

authors： Chen DS,Wu YQ,Zhang W,Jiang SJ,Chen SZ

更新日期：2016-06-07 00:00:00

abstract：:Gluconobacter oxydans sorbitol dehydrogenase (GoSLDH) exhibits a higher catalytic efficiency than other L-sorbose producing enzymes. During the reaction catalysed by GoSLDH, NADP+ is reduced to NADPH and D-sorbitol is oxidized to L-sorbose. However, GoSLDH activity is inhibited by the NADPH (Ki = 100 μM) formed during...

journal_title：Scientific reports

authors： Kim TS,Gao H,Li J,Kalia VC,Muthusamy K,Sohng JK,Kim IW,Lee JK

更新日期：2019-01-28 00:00:00

abstract：:Sorption and desorption determine the amount of an herbicide in soil solution. Therefore, knowledge of the sorption and desorption coefficients in different soils is an essential factor to estimate the potential for environmental contamination by herbicides. We evaluated the feasibility of multivariate and linear disc...

journal_title：Scientific reports

authors： Chagas PSFD,Souza MF,Dombroski JLD,Junior RSO,Nunes GHS,Pereira GAM,Silva TS,Passos ABRJ,Santos JBD,Silva DV

更新日期：2019-05-27 00:00:00

abstract：:The global DNA methylation degree may be a ubiquitous and early biomarker to distinguish cancer cells from benign cells. However, its usefulness in clinical diagnosis was scarcely demonstrated, because the cancer cells isolated from patients were usually very rare. Even if 10 mL of peripheral blood was sampled from a ...

journal_title：Scientific reports

authors： Si X,Zhao Y,Yang C,Zhang S,Zhang X

更新日期：2015-07-03 00:00:00

abstract：:TBC1D10C is a protein previously demonstrated to bind and inhibit Ras and Calcineurin. In cardiomyocytes, also CaMKII is inhibited and all three targeted enzymes are known to promote maladaptive cardiomyocyte hypertrophy. Here, in accordance with lack of Calcineurin inhibition in vivo, we did not observe a relevant an...

journal_title：Scientific reports

authors： Volland C,Bremer S,Hellenkamp K,Hartmann N,Dybkova N,Khadjeh S,Kutschenko A,Liebetanz D,Wagner S,Unsöld B,Didié M,Toischer K,Sossalla S,Hasenfuß G,Seidler T

更新日期：2016-09-26 00:00:00

abstract：:Recent genome-wide association studies (GWAS) of Parkinson's disease (PD) revealed at least 26 risk loci, with associated single nucleotide polymorphisms (SNPs) located in non-coding DNA having unknown functions in risk. In order to explore in which cell types these SNPs (and their correlated surrogates at r(2) ≥ 0.8)...

journal_title：Scientific reports

authors： Coetzee SG,Pierce S,Brundin P,Brundin L,Hazelett DJ,Coetzee GA

更新日期：2016-07-27 00:00:00

abstract：:In the attempt of implementing iron garnets with perpendicular magnetic anisotropy (PMA) in spintronics, the attention turned towards strain-grown iron garnets. One candidate is Tm3Fe5O12 (TmIG) which possesses an out-of-plane magnetic easy axis when grown under tensile strain. In this study, the effect of film thickn...

journal_title：Scientific reports

authors： Ciubotariu O,Semisalova A,Lenz K,Albrecht M

更新日期：2019-11-25 00:00:00

abstract：:Perinatally HIV-infected patients face the consequences of both chronic infection effects per se and long-term combination antiretroviral therapy (cART) on immunosenescence. Aims of our study were to evaluate which factors independently contribute to immunosenescence in HIV-infected young adults with a very different ...

journal_title：Scientific reports

authors： Quiros-Roldan E,Properzi M,Paghera S,Raffetti E,Castelli F,Imberti L

更新日期：2020-06-22 00:00:00

abstract：:Visceral adiposity is a risk factor for cardiovascular disorders, type 2 diabetes mellitus (T2D) and associated metabolic diseases. Sub-cutaneous fat is believed to be intrinsically different from visceral fat. To understand molecular mechanisms involved in metabolic advantages of fat transplantation, we studied a rat...

journal_title：Scientific reports

authors： Satoor SN,Puranik AS,Kumar S,Williams MD,Ghale M,Rahalkar A,Karandikar MS,Shouche Y,Patole M,Bhonde R,Yajnik CS,Hardikar AA

更新日期：2011-01-01 00:00:00

abstract：:Antimicrobial peptides (AMPs) are an important part of the human innate immune system for protection against bacterial infections, however the AMPs display varying degrees of activity against Staphylococcus aureus. Previously, we showed that inactivation of the ATP synthase sensitizes S. aureus towards the AMP antibio...

journal_title：Scientific reports

authors： Liu L,Beck C,Nøhr-Meldgaard K,Peschel A,Kretschmer D,Ingmer H,Vestergaard M

更新日期：2020-07-09 00:00:00

abstract：:Acid-sensing ion channels (ASICs) belong to the degenerin/epithelial sodium channel protein family that form mechanosensitive ion channels. Evidence as to whether or not ASICs activity is directly modulated by mechanical force is lacking. Human ASICs (hASIC1V3, hASIC2a and hASIC3a) were heterologously expressed as hom...

journal_title：Scientific reports

authors： Barth D,Fronius M

更新日期：2019-05-01 00:00:00

abstract：:Herein, we demonstrate a simple yet novel luminescence assay for visual chiral discrimination of cysteine. Thioglycolic acid (TGA)-capped cadmium-telluride (CdTe) quantum dots (QDs) exposing green emission were directly synthesized in aqueous solution. The interaction between cysteine molecules and CdTe QDs induced th...

journal_title：Scientific reports

authors： Ghasemi F,Hormozi-Nezhad MR,Mahmoudi M

更新日期：2017-04-18 00:00:00

abstract：:The bacterial flagellar motor is a unique supramolecular complex which converts ion flow into rotational force. Many biological devices mainly use two types of ions, proton and sodium ion. This is probably because of the fact that life originated in seawater, which is rich in protons and sodium ions. The polar flagell...

journal_title：Scientific reports

authors： Onoue Y,Iwaki M,Shinobu A,Nishihara Y,Iwatsuki H,Terashima H,Kitao A,Kandori H,Homma M

更新日期：2019-08-02 00:00:00

abstract：:While H2N2 viruses have been sporadically isolated from wild and domestic birds, H2N2 viruses have not been detected among human populations since 1968. Should H2N2 viruses adapt to domestic poultry they may pose a risk of infection to people, as most anyone born after 1968 would likely be susceptible to their infecti...

journal_title：Scientific reports

authors： Ma MJ,Yang XX,Qian YH,Zhao SY,Hua S,Wang TC,Chen SH,Ma GY,Sang XY,Liu LN,Wu AP,Jiang TJ,Gao YW,Gray GC,Zhao T,Ling X,Wang JL,Lu B,Qian J,Cao WC

更新日期：2014-12-23 00:00:00

abstract：:Toll-like receptor 7 (TLR7) mediates autoantigen and viral RNA-induced cytokine production. Increased TLR7 expression in human atherosclerotic lesions suggests its involvement in atherogenesis. Here we demonstrated TLR7 expression in macrophages, smooth muscle cells (SMCs), and endothelial cells from mouse atheroscler...

journal_title：Scientific reports

authors： Liu CL,Santos MM,Fernandes C,Liao M,Iamarene K,Zhang JY,Sukhova GK,Shi GP

更新日期：2017-04-12 00:00:00

abstract：:Small ruminants, including sheep and goats are natural hosts of scrapie, and the progression of scrapie pathogenesis is strongly influenced by polymorphisms in the prion protein gene (PRNP). Although Korean native goats have been consumed as meat and health food, the evaluation of the susceptibility to scrapie in thes...

journal_title：Scientific reports

authors： Kim SK,Kim YC,Won SY,Jeong BH

更新日期：2019-10-25 00:00:00

abstract：:Antibiotics in feed select for resistant strains and is thus a threat to human health. In this study, the effect of a multi-strain probiotic and antibiotics on the growth and health of broilers was studied. Equal numbers of broilers received on a daily basis either a multi-strain probiotic or a combination of sulphadi...

journal_title：Scientific reports

authors： Neveling DP,van Emmenes L,Ahire JJ,Pieterse E,Smith C,Dicks LMT

更新日期：2017-10-16 00:00:00

abstract：:E. coli is the main causative agent of mastitis in dairy cows, but the mechanism of molecular regulation underlying the occurrence and development of mastitis has not yet been fully elucidated. In this study, an E. coli-induced mastitis model was created and RNASeq technology was used to measure the miRNA expression p...

journal_title：Scientific reports

authors： Luoreng ZM,Wang XP,Mei CG,Zan LS

更新日期：2018-08-23 00:00:00

abstract：:Most of Quantum Secret Sharing(QSS) are (n, n) threshold 2-level schemes, in which the 2-level secret cannot be reconstructed until all n shares are collected. In this paper, we propose a (t, n) threshold d-level QSS scheme, in which the d-level secret can be reconstructed only if at least t shares are collected. Comp...

journal_title：Scientific reports

authors： Song XL,Liu YB,Deng HY,Xiao YG

更新日期：2017-07-25 00:00:00

abstract：:Preventing the protein-protein interaction of the cellular chromatin binding protein Lens Epithelium-Derived Growth Factor (LEDGF) and human immunodeficiency virus (HIV) integrase is an important possible strategy for anti-viral treatment for AIDS. We have used Intracellular Antibody Capture technology to isolate a si...

journal_title：Scientific reports

authors： Bao L,Hannon C,Cruz-Mignoni A,Ptchelkine D,Sun MY,Miller A,Bunjobpol W,Quevedo CE,Derveni M,Chambers J,Simmons A,Phillips SEV,Rabbitts TH

更新日期：2017-12-04 00:00:00

abstract：:Postmortem diagnosis of cantharidin-induced myocardial injury and postmortem interval estimation (PMI) are the challenges in forensic science. Cardiac biomarkers play an important role in the prediction and diagnosis of myocardial injury and can be used to determine the PMI. Based on the evidence, we aimed to explore ...

journal_title：Scientific reports

authors： Zhang Y,Yu Y,Zhang J,Guan C,Liu L,Ren L

更新日期：2020-07-21 00:00:00

abstract：:Vertical hot electron transistors incorporating atomically-thin 2D materials, such as graphene or MoS2, in the base region have been proposed and demonstrated in the development of electronic and optoelectronic applications. To the best of our knowledge, all previous 2D material-base hot electron transistors only cons...

journal_title：Scientific reports

authors： Lan YW,Torres CM Jr,Zhu X,Qasem H,Adleman JR,Lerner MB,Tsai SH,Shi Y,Li LJ,Yeh WK,Wang KL

更新日期：2016-09-01 00:00:00

abstract：:Clinicians often hesitate prescribing corticosteroids to treat corticosteroid-responsive conditions in sickle cell disease (SCD) patients because their use can be associated with complications (increased hospital readmission, rebound pain, strokes, avascular necrosis, acute chest syndrome). Consequently, SCD patients ...

journal_title：Scientific reports

authors： Almeida LEF,Damsker JM,Albani S,Afsar N,Kamimura S,Pratt D,Kleiner DE,Quezado M,Gordish-Dressman H,Quezado ZMN

更新日期：2018-04-17 00:00:00

abstract：:Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors (statins) have been shown to overcome tyrosine kinase inhibitor (TKI) resistance in epithelial growth factor receptor (EGFR) mutated non-small cell lung cancer (NSCLC) cells in vivo and in vitro. However, little is known about the putative induction of no...

journal_title：Scientific reports

authors： Otahal A,Aydemir D,Tomasich E,Minichsdorfer C

更新日期：2020-01-22 00:00:00

abstract：:Powdery mildew, a common cereal disease caused by the fungus Blumeria graminis, is a major limiting factor of barley production and genetic resistance is the most appropriate protection against it. To aid the breeding of new cultivars and their marketing, resistance genes can be postulated in homogeneous accessions. A...

journal_title：Scientific reports

authors： Dreiseitl A

更新日期：2020-11-03 00:00:00