Horizontal gene transfer events reshape the global landscape of arm race between viruses and homo sapiens.

abstract：:Pesticides, including neonicotinoids, typically target pest insects by being neurotoxic. Inadvertent exposure to foraging insect pollinators is usually sub-lethal, but may affect cognition. One cognitive trait, spatial working memory, may be important in avoiding previously-visited flowers and other spatial tasks such...

journal_title：Scientific reports

authors： Samuelson EE,Chen-Wishart ZP,Gill RJ,Leadbeater E

更新日期：2016-12-13 00:00:00

abstract：:The κ opioid receptor (κOR) is a member of G-protein-coupled receptors, and is considered as a promising drug target for treating neurological diseases. κOR selective 6'-GNTI was proved to be a G-protein biased agonist, whereas 5'-GNTI acts as an antagonist. To investigate the molecular mechanism of how these two liga...

journal_title：Scientific reports

authors： Cheng J,Sun X,Li W,Liu G,Tu Y,Tang Y

更新日期：2016-01-08 00:00:00

abstract：:Coxsackievirus A24 variant (CVA24v) is a major causative agent of acute hemorrhagic conjunctivitis outbreaks worldwide, yet the evolutionary and transmission dynamics of the virus remain unclear. To address this, we analyzed and compared the 3C and partial VP1 gene regions of CVA24v isolates obtained from five outbrea...

journal_title：Scientific reports

authors： Fonseca MC,Pupo-Meriño M,García-González LA,Resik S,Hung LH,Muné M,Rodríguez H,Morier L,Norder H,Sarmiento L

更新日期：2020-08-13 00:00:00

abstract：:Hand, foot, and mouth disease (HFMD) is a common childhood illness caused by enteroviruses. HFMD outbreaks and reported cases have sharply increased in China since 2008. Epidemiological and clinical data of HFMD cases reported in Henan Province were collected from 2008 to 2013. Clinical specimens were obtained from a ...

journal_title：Scientific reports

authors： Huang X,Wei H,Wu S,Du Y,Liu L,Su J,Xu Y,Wang H,Li X,Wang Y,Liu G,Chen W,Klena JD,Xu B

更新日期：2015-03-10 00:00:00

abstract：:A singular adaptive phenotype of a parthenogenetic insect species (Acyrthosiphon pisum) was selected in cold conditions and is characterized by a remarkable apparition of a greenish colour. The aphid pigments involve carotenoid genes well defined in chloroplasts and cyanobacteria and amazingly present in the aphid gen...

journal_title：Scientific reports

authors： Valmalette JC,Dombrovsky A,Brat P,Mertz C,Capovilla M,Robichon A

更新日期：2012-01-01 00:00:00

abstract：:Malignant peripheral nerve sheath tumors (MPNST) are aggressive cancers that occur spontaneously (sporadic MPNST) or from benign plexiform neurofibromas in neurofibromatosis type 1 (NF1) patients. MPNSTs metastasize easily, are therapy resistant and are frequently fatal. The molecular changes underlying the malignant ...

journal_title：Scientific reports

authors： Amirnasr A,Verdijk RM,van Kuijk PF,Kartal P,Vriends ALM,French PJ,van Royen ME,Taal W,Sleijfer S,Wiemer EAC

更新日期：2020-02-19 00:00:00

abstract：:The production of male and female offspring is often determined by the presence of specific sex chromosomes which control sex-specific expression, and sex chromosomes evolve through reduced recombination and specialized gene content. Here we present the genomes of Chrysomya rufifacies, a monogenic blow fly (females pr...

journal_title：Scientific reports

authors： Andere AA,Pimsler ML,Tarone AM,Picard CJ

更新日期：2020-09-25 00:00:00

abstract：:Three H10 subtype avian influenza viruses were isolated from domestic ducks in China, designated as SH602/H10N8, FJ1761/H10N3 and SX3180/H10N7, with an intravenous pathogenicity index (IVPI) of 0.39, 1.60, and 1.27, respectively. These H10 viruses showed a complex pathology pattern in different species, although full ...

journal_title：Scientific reports

authors： Zhang M,Zhang X,Xu K,Teng Q,Liu Q,Li X,Yang J,Xu J,Chen H,Zhang X,Li Z

更新日期：2016-09-28 00:00:00

abstract：:Biological invasions are a major threat to biodiversity and ecosystem functioning. Successful invasions depend on the interplay of multiple abiotic and biotic factors, however, the process of the invasion itself is often overlooked. The temporal variation of environmental factors suggests that a 'window of opportunity...

journal_title：Scientific reports

authors： Bolius S,Wiedner C,Weithoff G

更新日期：2019-06-05 00:00:00

abstract：:Protandric species switch sex during their lifetime. According to theory, the time (body size) at which sex change occurs is determined by the reproductive success of individuals affected by social interactions as well as by post-copulatory factors. Experimental evidence is biased to few social systems making the expl...

journal_title：Scientific reports

authors： Brante A,Quiñones A,Silva F

更新日期：2016-07-07 00:00:00

abstract：:Curvature components derived from satellite gravity gradients provide new global views of Earth's structure. The satellite gravity gradients are based on the GOCE satellite mission and we illustrate by curvature images how the Earth is seen differently compared to seismic imaging. Tectonic domains with similar seismic...

journal_title：Scientific reports

authors： Ebbing J,Haas P,Ferraccioli F,Pappa F,Szwillus W,Bouman J

更新日期：2018-11-05 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Mei X,Glueckert R,Schrott-Fischer A,Li H,Ladak HM,Agrawal SK,Rask-Andersen H

更新日期：2020-05-01 00:00:00

abstract：:Here we demonstrate that aerosols of host directed therapies [HDT] administered during a chronic Mycobacterium tuberculosis (Mtb) infection have bactericidal effect. The pulmonary bacterial load of C57BL/6 mice chronically infected with Mtb was reduced by 1.7 and 0.6 log10CFU after two weeks of treatment via aerosol d...

journal_title：Scientific reports

authors： Upadhyay R,Sanchez-Hidalgo A,Wilusz CJ,Lenaerts AJ,Arab J,Yeh J,Stefanisko K,Tarasova NI,Gonzalez-Juarrero M

更新日期：2018-11-09 00:00:00

abstract：:Nuclei detection is often a critical initial step in the development of computer aided diagnosis and prognosis schemes in the context of digital pathology images. While over the last few years, a number of nuclei detection methods have been proposed, most of these approaches make idealistic assumptions about the stain...

journal_title：Scientific reports

authors： Lu C,Xu H,Xu J,Gilmore H,Mandal M,Madabhushi A

更新日期：2016-10-03 00:00:00

abstract：:In this study, genomic DNA was screened from Halobacillus andaensis NEAU-ST10-40T by selection in Escherichia coli KNabc lacking three major Na+/H+ antiporters. One gene designated upf0118 exhibiting Na+(Li+)/H+ antiport activity was finally cloned. Protein alignment showed that UPF0118 shares the highest identity of ...

journal_title：Scientific reports

authors： Dong P,Wang L,Song N,Yang L,Chen J,Yan M,Chen H,Zhang R,Li J,Abdel-Motaal H,Jiang J

更新日期：2017-04-04 00:00:00

abstract：:Previous studies have shown that it is possible to nutritionally program gilthead seabream offspring through fish oil (FO) replacement by vegetable oils (VO) in the broodstock diet, to improve their ability to grow fast when fed low fish meal (FM) and FO diets during grow-out phase. However, in those studies broodstoc...

journal_title：Scientific reports

authors： Ferosekhan S,Xu H,Turkmen S,Gómez A,Afonso JM,Fontanillas R,Rosenlund G,Kaushik S,Izquierdo M

更新日期：2020-09-23 00:00:00

abstract：:We investigated the ocular surface (OS) system modifications after completely successful glaucoma surgery in thirty-eight patients undergoing trabeculectomy (surgical group), using laser scanning confocal microscopy (LSCM) and impression cytology (IC). Twenty-six medically controlled glaucomatous patients served as co...

journal_title：Scientific reports

authors： Agnifili L,Brescia L,Oddone F,Sacchi M,D'Ugo E,Di Marzio G,Perna F,Costagliola C,Mastropasqua R

更新日期：2019-08-05 00:00:00

abstract：:Recent studies suggest that mRNAs may be differentially expressed between males and females. This study aimed to perform expression analysis of mRNA and its main regulatory molecule, microRNA (miRNA), to discuss the potential sex-specific expression patterns using abnormal expression profiles from The Cancer Genome At...

journal_title：Scientific reports

authors： Guo L,Zhang Q,Ma X,Wang J,Liang T

更新日期：2017-01-03 00:00:00

abstract：:The arrival of the Longobards in Northern Italy in 568 CE marked a period of renewed political stability in the Peninsula after the collapse of the Western Roman Empire. The trajectory of the spread of Longobards in Italy across the Alps and into the South is known from many literary sources. However, their mobility a...

journal_title：Scientific reports

authors： Francisci G,Micarelli I,Iacumin P,Castorina F,Di Vincenzo F,Di Matteo M,Giostra C,Manzi G,Tafuri MA

更新日期：2020-07-15 00:00:00

abstract：:Engineering of efflux pumps is a promising way to improve host's tolerance to biofuels such as medium-chain alcohols (CmOHs); however, this strategy is restricted by poor understanding of the efflux pumps engaged in extrusion of solvents. In this study, several Escherichia coli mutants of multidrug transporters were e...

journal_title：Scientific reports

authors： Wang C,Yang L,Shah AA,Choi ES,Kim SW

更新日期：2015-11-13 00:00:00

abstract：:Upwelling off Vietnam in the South China Sea (SCS) and the Sumatra-Java upwelling in the Indian Ocean significantly modulate regional variation in climate. Although located in different hemispheres, these upwellings nearly concur during the boreal summer; both are the result of wind-induced Ekman divergence. Beyond se...

journal_title：Scientific reports

authors： Wu CR,Wang LC,Wang YL,Lin YF,Chiang TL,Hsin YC

更新日期：2019-03-06 00:00:00

abstract：:Mountain glaciers form landscapes with U-shaped valleys, roche moutonées and overdeepenings through bedrock erosion. However, little evidence for active glacial carving has been provided particularly for areas above the Equilibrium Line Altitude (ELA) where glaciers originate. This is mainly due to our lack of informa...

journal_title：Scientific reports

authors： Nishiyama R,Ariga A,Ariga T,Lechmann A,Mair D,Pistillo C,Scampoli P,Valla PG,Vladymyrov M,Ereditato A,Schlunegger F

更新日期：2019-05-06 00:00:00

abstract：:There is a growing interest in developing microphysiological systems that can be used to model both normal and pathological human organs in vitro. This "organs-on-chips" approach aims to capture key structural and physiological characteristics of the target tissue. Here we describe in vitro vascularized microtumors (V...

journal_title：Scientific reports

authors： Sobrino A,Phan DT,Datta R,Wang X,Hachey SJ,Romero-López M,Gratton E,Lee AP,George SC,Hughes CC

更新日期：2016-08-23 00:00:00

abstract：:Microvascular endothelial cell heterogeneity and its relationship to hemodynamics remains poorly understood due to a lack of sufficient methods to examine these parameters in vivo at high resolution throughout an angiogenic network. The availability of surrogate markers for functional vascular proteins, such as green ...

journal_title：Scientific reports

authors： Kelly-Goss MR,Ning B,Bruce AC,Tavakol DN,Yi D,Hu S,Yates PA,Peirce SM

更新日期：2017-08-22 00:00:00

abstract：:Great interest has been shown in mesenchymal stem cell (MSC) therapy in a wide variety of clinical domains. However, the therapeutic efficiency depends on the proliferation and migration of MSCs. Chemokine receptors are involved in regulating the proliferation and migration to the specific organs of MSCs in different ...

journal_title：Scientific reports

authors： Liu L,Chen JX,Zhang XW,Sun Q,Yang L,Liu A,Hu S,Guo F,Liu S,Huang Y,Yang Y,Qiu HB

更新日期：2018-01-09 00:00:00

abstract：:In this study, we made a comparative efficacy and safety assessment of two different fixed combinations of drugs, viz., tafluprost/timolol (TAF/TIM) and latanoprost/carteolol (LAT/CAR), by determining their effects on intraocular pressure (IOP) in ocular normotensive monkeys and examining their toxic effects on ocular...

journal_title：Scientific reports

authors： Fuwa M,Shimazaki A,Mieda M,Yamashita N,Akaishi T,Taniguchi T,Kato M

更新日期：2019-05-16 00:00:00

abstract：:Functional Dyspepsia-Post-prandial Distress Syndrome (FD-PDS) was associated with mood-related increases in resting activity and lowered activation threshold in the somatosensory cortex (SSC), insula and perigenual anterior cingulate cortex(pgACC) in functional imaging studies. The underlying cortical neurochemical ch...

journal_title：Scientific reports

authors： Mak ADP,Northoff G,Yeung DKW,Chu WCW,Hui SCN,Cheung C,Ching J,Lam L,Lee S,Wu J

更新日期：2017-06-20 00:00:00

abstract：:Due to the increasing concern of using smallpox virus as biological weapons for terrorist attack, there is renewed interest in studying the pathogenesis of human smallpox and development of new therapies. Animal models are highly demanded for efficacy and safety examination of new vaccines and therapeutic drugs. Here,...

journal_title：Scientific reports

authors： Liu Q,Fan C,Zhou S,Guo Y,Zuo Q,Ma J,Liu S,Wu X,Peng Z,Fan T,Guo C,Shen Y,Huang W,Li B,He Z,Wang Y

更新日期：2015-08-03 00:00:00

abstract：:To assess the prevalence of cataract and cataract surgery in a population from Russia, we conducted the population-based Ural Eye and Medical Study with 5899 participants (80.5% out of 7328 eligible individuals), with an age of 40 + years as the eligibility criterion. In the phakic population, the prevalence of nuclea...

journal_title：Scientific reports

authors： Bikbov MM,Kazakbaeva GM,Gilmanshin TR,Zainullin RM,Nuriev IF,Zaynetdinov AF,Israfilova GZ,Panda-Jonas S,Arslangareeva II,Rakhimova EM,Rusakova IA,Jonas JB

更新日期：2020-10-23 00:00:00

abstract：:Propofol sedation has been applied during esophagogastroduodenoscopy procedures, but whether topical pharyngeal anesthesia should be administered at the same time has rarely been reported. Our study examined the role of topical pharyngeal anesthesia in sedated endoscopies in a randomized controlled double-blinded clin...

journal_title：Scientific reports

authors： Sun X,Xu Y,Zhang X,Li A,Zhang H,Yang T,Liu Y

更新日期：2018-04-27 00:00:00