Abstract:
:New anti-infective drugs are an unmet necessity of modern medicine. The use of ∼omics technologies has exponentially increased the knowledge on active anti-infective structures, where to search for them and their mechanisms of action. Research involving extreme and unique environments (such as endophytes) revealed their potential for many yet unknown active molecules. This work intends to review a recent research involving discovery of secondary metabolites with an established anti-infective action which was mediated by one of the ∼omics sciences: genomics, proteomics, transcriptomics, metabolomics, glycomics or their combinations, as well as the software at the base of these discoveries.
journal_name
Curr Opin Pharmacoljournal_title
Current opinion in pharmacologyauthors
Maldonado-Carmona N,Vázquez-Hernández M,Patiño Chávez OJ,Rodríguez-Luna SD,Jiménez Rodríguez O,Sanchez S,Ceapă CDdoi
10.1016/j.coph.2019.02.008subject
Has Abstractpub_date
2019-10-01 00:00:00pages
1-7eissn
1471-4892issn
1471-4973pii
S1471-4892(18)30134-6journal_volume
48pub_type
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