Abstract:
:The evolving policies regarding the use of therapeutic Cannabis have steadily increased the public interest in its use as a complementary and alternative medicine in several disorders, including inflammatory bowel disease. Endocannabinoids represent both an appealing therapeutic strategy and a captivating scientific dilemma. Results from clinical trials have to be carefully interpreted owing to possible reporting-biases related to cannabinoids psychotropic effects. Moreover, discriminating between symptomatic improvement and the real gain on the underlying inflammatory process is often challenging. This review summarizes the advances and latest discovery in this ever-changing field of investigation, highlighting the main limitations in the current use of these drugs in clinical practice and the possible future perspectives to overcome these flaws.
journal_name
Curr Opin Pharmacoljournal_title
Current opinion in pharmacologyauthors
Pesce M,Esposito G,Sarnelli Gdoi
10.1016/j.coph.2018.08.009subject
Has Abstractpub_date
2018-12-01 00:00:00pages
81-86eissn
1471-4892issn
1471-4973pii
S1471-4892(18)30018-3journal_volume
43pub_type
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