Abstract:
:Nanotechnology in medicine-nanomedicine-is extensively employed to diagnose, treat, and prevent pulmonary diseases. Over the last few years, this brave new world has made remarkable progress, offering opportunities to address historical clinical challenges in pulmonary diseases including multidrug resistance, adverse side effects of conventional therapeutic agents, novel imaging, and earlier disease detection. Nanomedicine is also being applied to tackle the new emerging infectious diseases, including severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East Respiratory Syndrome Coronavirus (MERS-CoV), influenza A virus subtype H1N1 (A/H1N1), and more recently, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In this review we provide both a historical overview of the application of nanomedicine to respiratory diseases and more recent cutting-edge approaches such as nanoparticle-mediated combination therapies, novel double-targeted nondrug delivery system for targeting, stimuli-responsive nanoparticles, and theranostic imaging in the diagnosis and treatment of pulmonary diseases.
journal_name
Curr Opin Pharmacoljournal_title
Current opinion in pharmacologyauthors
Doroudian M,O' Neill A,Mac Loughlin R,Prina-Mello A,Volkov Y,Donnelly SCdoi
10.1016/j.coph.2020.11.002subject
Has Abstractpub_date
2020-12-17 00:00:00pages
85-92eissn
1471-4892issn
1471-4973pii
S1471-4892(20)30129-6journal_volume
56pub_type
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