Temporal variability of diazotroph community composition in the upwelling region off NW Iberia.

abstract：:Mesothelin is an emerging cell surface target in mesothelioma and other solid tumors. Most antibody drug candidates recognize highly immunogenic Region I (296-390) on mesothelin. Here, we report a group of high-affinity non-Region I rabbit monoclonal antibodies. These antibodies do not compete for mesothelin binding w...

journal_title：Scientific reports

authors： Zhang YF,Phung Y,Gao W,Kawa S,Hassan R,Pastan I,Ho M

更新日期：2015-05-21 00:00:00

abstract：:An effective method, involving time and frequency domains was developed to interpret seismic precursors by comparing groundwater-level fluctuations recorded immediately and long before the occurrence of a known earthquake. The proposed method, consisting of the pre-processing (3-point filtering, band-pass filtering, a...

journal_title：Scientific reports

authors： Hwang HS,Hamm SY,Cheong JY,Lee SH,Ha K,Lee C,Woo NC,Yun SM,Kim KH

更新日期：2020-05-12 00:00:00

abstract：:Although large populations feel fatigue, the standardized medicinal therapy is currently absent. In this study, we determined whether 5-aminolevulinic acid (5-ALA) supplementation alleviates the feeling of fatigue in healthy subjects who feel chronic physical tiredness. Males and females between ages of 20 and 64 who ...

journal_title：Scientific reports

authors： Higashikawa F,Kanno K,Ogata A,Sugiyama M

更新日期：2020-09-29 00:00:00

abstract：:Aluminium adjuvants remain the most widely used and effective adjuvants in vaccination and immunotherapy. Herein, the particle size distribution (PSD) of aluminium oxyhydroxide and aluminium hydroxyphosphate adjuvants was elucidated in attempt to correlate these properties with the biological responses observed post v...

journal_title：Scientific reports

authors： Mold M,Shardlow E,Exley C

更新日期：2016-08-12 00:00:00

abstract：:Free standing, atomically thin transition metal dichalcogenides are a new class of ultralightweight nanoelectromechanical systems with potentially game-changing electro- and opto-mechanical properties, however, the energy dissipation pathways that fundamentally limit the performance of these systems is still poorly un...

journal_title：Scientific reports

authors： Matis BR,Houston BH,Baldwin JW

更新日期：2017-07-18 00:00:00

abstract：:The striped venus (Chamelea gallina) is an important economic resource in the Mediterranean Basin; this species has exhibited a strong quantitative decline in the Adriatic Sea. The aim of this work was to provide a comprehensive view of the biological status of C. gallina to elucidate the bioecological characteristics...

journal_title：Scientific reports

authors： Carducci F,Biscotti MA,Trucchi E,Giuliani ME,Gorbi S,Coluccelli A,Barucca M,Canapa A

更新日期：2020-11-05 00:00:00

abstract：:Glyoxalase pathway plays an important role in stress adaptation and many clinical disorders. The first enzyme of this pathway, glyoxalase I (GlxI), uses methylglyoxal as a substrate and requires either Ni(II)/Co(II) or Zn(II) for activity. Here we have investigated the origin of different metal ion specificities of Gl...

journal_title：Scientific reports

authors： Kaur C,Vishnoi A,Ariyadasa TU,Bhattacharya A,Singla-Pareek SL,Sopory SK

更新日期：2013-11-13 00:00:00

abstract：:The pulsed events of rainstorm erosion on the Loess Plateau are well-known, but little information is available concerning the characteristics of superficial soil erosion processes caused by heavy rainstorms at the watershed scale. This study statistically evaluated characteristics of pulsed runoff-erosion events base...

journal_title：Scientific reports

authors： Wu L,Jiang J,Li GX,Ma XY

更新日期：2018-02-27 00:00:00

abstract：:The estrogen receptor (ER) regulates the survival and growth of breast cancer cells, but it is less clear how components of the tissue microenvironment affect ER-mediated responses. We set out to test how human mammary fibroblasts (HMFs) modulate ER signaling and downstream cellular responses. We exposed an organotypi...

journal_title：Scientific reports

authors： Morgan MM,Livingston MK,Warrick JW,Stanek EM,Alarid ET,Beebe DJ,Johnson BP

更新日期：2018-05-08 00:00:00

abstract：:Mycobacterium spp. are renowned for being the causative agent of diseases like leprosy, Buruli ulcer and tuberculosis in human beings. With more and more mycobacterial genomes being sequenced, any knowledge generated from comparative genomic analysis would provide better insights into the biology, evolution, phylogeny...

journal_title：Scientific reports

authors： Choo SW,Ang MY,Dutta A,Tan SY,Siow CC,Heydari H,Mutha NV,Wee WY,Wong GJ

更新日期：2015-12-15 00:00:00

abstract：:By employing a single AlGaN layer with low Al composition, high quality and uniformity AlGaN/GaN heterostructures have been successfully grown on Si substrates by metal-organic chemical vapor deposition (MOCVD). The heterostructures exhibit a high electron mobility of 2150 cm(2)/Vs with an electron density of 9.3 × 10...

journal_title：Scientific reports

authors： Cheng J,Yang X,Sang L,Guo L,Zhang J,Wang J,He C,Zhang L,Wang M,Xu F,Tang N,Qin Z,Wang X,Shen B

更新日期：2016-03-10 00:00:00

abstract：:Children with autistic spectrum disorders (ASD) experience persistent disrupted coordination in interpersonal synchronisation that is thought to be associated with deficits in neural connectivity. Robotic interventions have been explored for use with ASD children worldwide revealing that robots encourage one-to-one so...

journal_title：Scientific reports

authors： Giannopulu I,Etournaud A,Terada K,Velonaki M,Watanabe T

更新日期：2020-10-15 00:00:00

abstract：:Rising temperatures in the Arctic cause accelerated mass loss from the Greenland Ice Sheet and reduced sea ice cover. Tidewater outlet glaciers represent direct connections between glaciers and the ocean where melt rates at the ice-ocean interface are influenced by ocean temperature and circulation. However, few measu...

journal_title：Scientific reports

authors： Bendtsen J,Mortensen J,Lennert K,K Ehn J,Boone W,Galindo V,Hu YB,Dmitrenko IA,Kirillov SA,Kjeldsen KK,Kristoffersen Y,G Barber D,Rysgaard S

更新日期：2017-07-10 00:00:00

abstract：:The control of structural and chemical transitions in bimetallic nanoalloys at finite temperatures is one of the challenges for their use in advanced applications. Comparing Nested Sampling and Molecular Dynamics simulations, we investigate the phase changes of CuPt nanoalloys with the aim to elucidate the role of kin...

journal_title：Scientific reports

authors： Rossi K,Pártay LB,Csányi G,Baletto F

更新日期：2018-06-14 00:00:00

abstract：:Although extensive studies have focused on the development of acute mountain sickness (AMS), the exact mechanisms of AMS are still obscure. In this study, we used isobaric tags for relative and absolute quantitation (iTRAQ) proteomic analysis to identify novel AMS-associated biomarkers in human plasma. After 9 hours o...

journal_title：Scientific reports

authors： Lu H,Wang R,Li W,Xie H,Wang C,Hao Y,Sun Y,Jia Z

更新日期：2018-01-19 00:00:00

abstract：:Drug-induced cholestasis is a leading cause of drug withdrawal. However, the use of primary human hepatocytes (PHHs), the gold standard for predicting cholestasis in vitro, is limited by their high cost and batch-to-batch variability. Mature hepatocyte characteristics have been observed in human induced hepatocytes (h...

journal_title：Scientific reports

authors： Ni X,Gao Y,Wu Z,Ma L,Chen C,Wang L,Lin Y,Hui L,Pan G

更新日期：2016-12-09 00:00:00

abstract：:The human brain contains areas that respond selectively to faces, bodies and scenes. Neuroimaging studies have shown that a subset of these areas preferentially respond more to moving than static stimuli, but the reasons for this functional dissociation remain unclear. In the present study, we simultaneously mapped th...

journal_title：Scientific reports

authors： Pitcher D,Ianni G,Ungerleider LG

更新日期：2019-06-03 00:00:00

abstract：:Rats are effective model animals and have contributed to the development of human medicine and basic research. However, the application of reproductive engineering techniques to rats is not as advanced compared with mice, and genome editing in rats has not been achieved using embryos obtained by in vitro fertilization...

journal_title：Scientific reports

authors： Honda A,Tachibana R,Hamada K,Morita K,Mizuno N,Morita K,Asano M

更新日期：2019-08-09 00:00:00

abstract：:Matrices for sustained release of drugs have been based on polymers, biomaterials and oxides. The use of the major family of metals as matrices for sustained release is, to the best of our knowledge, unknown. In this context we describe a new family of bio-composites for sustained release of drugs, namely analgesic dr...

journal_title：Scientific reports

authors： Menagen B,Pedahzur R,Avnir D

更新日期：2017-06-23 00:00:00

abstract：:The quantities and proportions of protein fractions have notable effects on the nutritional and technological value of milk. Although much is known about the effects of genetic variants on milk proteins, the complex relationships among the set of genes and pathways regulating the different protein fractions synthesis ...

journal_title：Scientific reports

authors： Pegolo S,Mach N,Ramayo-Caldas Y,Schiavon S,Bittante G,Cecchinato A

更新日期：2018-01-12 00:00:00

abstract：:The present study applied the PacBio single molecule, real-time sequencing technology (SMRT) in evaluating the quality of silage production. Specifically, we produced four types of Medicago sativa silages by using four different lactic acid bacteria-based additives (AD-I, AD-II, AD-III and AD-IV). We monitored the cha...

journal_title：Scientific reports

authors： Bao W,Mi Z,Xu H,Zheng Y,Kwok LY,Zhang H,Zhang W

更新日期：2016-06-24 00:00:00

abstract：:The benzodiazepine midazolam is widely used in critical care medicine. Midazolam has a clinically active metabolite, 1-hydroxymidazolam. The contribution of 1-hydroxymidazolam to the effects of midazolam is controversial. The aim of the current study was to compare the actions of midazolam and 1-hydroxymidazolam on ne...

journal_title：Scientific reports

authors： Balk M,Hentschke H,Rudolph U,Antkowiak B,Drexler B

更新日期：2017-06-14 00:00:00

abstract：:Lipid droplet (LD), a multi-functional organelle, is often found to associate with other cellular membranous structures and vary in size in a given cell, which may be related to their functional diversity. Here we established a method to separate LD subpopulations from isolated CHO K2 LDs into three different size cat...

journal_title：Scientific reports

authors： Zhang S,Wang Y,Cui L,Deng Y,Xu S,Yu J,Cichello S,Serrero G,Ying Y,Liu P

更新日期：2016-07-08 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is an important risk factor for the development of type 2 diabetes mellitus. Interferon gamma-induced protein 10 (IP-10), a proinflammatory chemokine, plays a crucial role in inflammatory diseases. This cross-sectional pilot study investigated whether circulating IP-10 is assoc...

journal_title：Scientific reports

authors： Chang CC,Wu CL,Su WW,Shih KL,Tarng DC,Chou CT,Chen TY,Kor CT,Wu HM

更新日期：2015-05-11 00:00:00

abstract：:In situ HfB2-SiC-VSi2 composite was fabricated by reactive pressureless sintering at the temperature of 2150 °C for 4 h under a vacuum atmosphere. In situ SiC and VSi2 reinforcements were formed using VC and Si powders as starting materials according to the following reaction: VC + 3Si = SiC + VSi2. Microstructural st...

journal_title：Scientific reports

authors： Ghadami S,Taheri-Nassaj E,Baharvandi HR,Ghadami F

更新日期：2020-10-06 00:00:00

abstract：:Evaluations of restoration success usually focus on the structural aspects of ecosystems. Pollination, as an important functional aspect, is often overlooked. Here, the shifts in pollinator assemblage and pollen limitation in the desert shrub Caragana microphylla were examined along a restoration gradient in Horqin Sa...

journal_title：Scientific reports

authors： Pan CC,Qu H,Feng Q,Liu LD,Zhao HL,Li YL,Li YQ,Zhang TH,Liu XP

更新日期：2017-12-04 00:00:00

abstract：:AS1411 is a G-rich DNA oligonucleotide that functions as an aptamer of the protein nucleolin, found at high levels on the surface of cancer cells but not on the surface of normal cells. Herein, we have studied AS1411 as a supramolecular carrier for the delivery of an acridine-based G-quadruplex ligand, C8, to HeLa can...

journal_title：Scientific reports

authors： Carvalho J,Paiva A,Cabral Campello MP,Paulo A,Mergny JL,Salgado GF,Queiroz JA,Cruz C

更新日期：2019-05-28 00:00:00

abstract：:Twirling is a technique widely used for converting arbitrary noise channels into Pauli channels in error threshold estimations of quantum error correction codes. It is vitally useful both in real experiments and in classical quantum simulations. Minimising the size of the twirling gate set increases the efficiency of ...

journal_title：Scientific reports

authors： Cai Z,Benjamin SC

更新日期：2019-08-02 00:00:00

abstract：:Microscopic swimming devices hold promise for radically new applications in lab-on-a-chip and microfluidic technology, diagnostics and drug delivery etc. In this paper, we demonstrate the experimental verification of a new class of autonomous ferromagnetic swimming devices, actuated and controlled solely by an oscilla...

journal_title：Scientific reports

authors： Hamilton JK,Petrov PG,Winlove CP,Gilbert AD,Bryan MT,Ogrin FY

更新日期：2017-03-09 00:00:00

abstract：:Exosomes are nano-sized endosome-derived small intraluminal vesicles, which are important facilitators of intercellular communication by transporting contents, such as protein, mRNA, and microRNAs, between neighboring cells, such as in the tumor microenvironment. The purpose of this study was to understand the mechani...

journal_title：Scientific reports

authors： Su MJ,Aldawsari H,Amiji M

更新日期：2016-07-22 00:00:00