Abstract：
:Mycobacterium spp. are renowned for being the causative agent of diseases like leprosy, Buruli ulcer and tuberculosis in human beings. With more and more mycobacterial genomes being sequenced, any knowledge generated from comparative genomic analysis would provide better insights into the biology, evolution, phylogeny and pathogenicity of this genus, thus helping in better management of diseases caused by Mycobacterium spp.With this motivation, we constructed MycoCAP, a new comparative analysis platform dedicated to the important genus Mycobacterium. This platform currently provides information of 2108 genome sequences of at least 55 Mycobacterium spp. A number of intuitive web-based tools have been integrated in MycoCAP particularly for comparative analysis including the PGC tool for comparison between two genomes, PathoProT for comparing the virulence genes among the Mycobacterium strains and the SuperClassification tool for the phylogenic classification of the Mycobacterium strains and a specialized classification system for strains of Mycobacterium abscessus. We hope the broad range of functions and easy-to-use tools provided in MycoCAP makes it an invaluable analysis platform to speed up the research discovery on mycobacteria for researchers. Database URL: http://mycobacterium.um.edu.my.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Choo SW,Ang MY,Dutta A,Tan SY,Siow CC,Heydari H,Mutha NV,Wee WY,Wong GJdoi
10.1038/srep18227subject
Has Abstractpub_date
2015-12-15 00:00:00pages
18227issn
2045-2322pii
srep18227journal_volume
5pub_type
杂志文章abstract：:Multiple predatory insect lineages have developed a raptorial lifestyle by which they strike and hold prey using modified forelegs armed with spine-like structures and other integumentary specialisations. However, how structures enabling the raptorial function evolved in insects remains largely hypothetical or inferre...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-49398-1
更新日期：2019-09-13 00:00:00
abstract：:An appropriate tillage method must be implemented by maize growers to improve phosphorus dynamics in the soil in order to increase phosphorus uptake by plant. The objective of this study was to investigate the effects of tillage systems on phosphorus and its fractions in rhizosphere and non-rhizosphere soils under mai...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-63567-7
更新日期：2020-04-20 00:00:00
abstract：:Safe management of high level nuclear waste is a worldwide significant issue for which vitrification has been selected by many countries. There exists a crucial need for improving our understanding of the ageing of the glass under irradiation. While external irradiation by ions provides a rapid simulation of damage in...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep25499
更新日期：2016-05-05 00:00:00
abstract：:Overuse of nitrogen (N) fertilizer has led to low N use efficiency (NUE) and high N loss in single rice cropping systems in southeast China. Application of controlled-release urea (CRU) is considered as an effective N fertilizer practice for improving crop yields and NUE. Here, field experiments were conducted during ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-67110-6
更新日期：2020-06-26 00:00:00
abstract：:Antiretroviral therapy-naive HIV-1 infected infants experience poor viral containment and rapid disease progression compared to adults. Viral factors (e.g. transmitted cytotoxic T- lymphocyte (CTL) escape mutations) or infant factors (e.g. reduced CTL functional capacity) may explain this observation. We assessed CTL ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep29536
更新日期：2016-07-12 00:00:00
abstract：:Quantum coherence and quantum correlations are important quantum resources for quantum computation and quantum information. In this paper, using entropy-based measures, we investigate the relationships between quantum correlated coherence, which is the coherence between subsystems, and two main kinds of quantum correl...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09332-9
更新日期：2017-09-21 00:00:00
abstract：:Range-wide population studies of wide spread species are often associated with complex diversity patterns resulting from genetically divergent evolutionary significant units (ESUs). The compound evolutionary history creating such a pattern of diversity can be inferred through molecular analyses. Asparagus cochinchinen...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-46275-9
更新日期：2019-07-05 00:00:00
abstract：:Demand for clinical decision support systems in medicine and self-diagnostic symptom checkers has substantially increased in recent years. Existing platforms rely on knowledge bases manually compiled through a labor-intensive process or automatically derived using simple pairwise statistics. This study explored an aut...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-05778-z
更新日期：2017-07-20 00:00:00
abstract：:To increase the yield potential while limiting the environmental impact of N management practices is an important issue in rice cultivation. The large-grain rice cultivar Akita 63 showed higher N-use efficiency for grain production. To elucidate this, we analyzed yield characteristics of Akita 63 in comparison with th...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-69289-0
更新日期：2020-07-22 00:00:00
abstract：:High Refractive Index (HRI) dielectric nanoparticles have been proposed as an alternative to metallic ones due to their low absorption and magnetodielectric response in the VIS and NIR ranges. For the latter, important scattering directionality effects can be obtained. Also, systems constituted by dimers of HRI dielec...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-11401-y
更新日期：2017-09-11 00:00:00
abstract：:Nutritional supplements may be important on cognition but the evidence is heterogeneous. This meta-analysis aimed (1) to determine whether nutritional supplements provided to pregnant women or young children could improve cognitive development of children in developing countries, and (2) to explore how supplementation...
journal_title：Scientific reports
pub_type： 杂志文章,meta分析
doi：10.1038/s41598-017-11023-4
更新日期：2017-09-06 00:00:00
abstract：:Mesenchymal stromal cells (MSCs) are a potential therapy for many chronic inflammatory diseases due to their regenerative, immunologic and anti-inflammatory properties. The two-way dialogue between MSCs and macrophages is crucial to tissue regeneration and repair. Previous research demonstrated that murine adipose-der...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-56835-8
更新日期：2019-12-30 00:00:00
abstract：:In order to understand the physical properties of materials it is necessary to determine the 3D positions of all atoms. There has been significant progress towards this goal using electron tomography. However, this method requires a relatively high electron dose and often extended acquisition times which precludes the...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-10654-x
更新日期：2017-09-07 00:00:00
abstract：:CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage. CD43 is directly involved in the contact between cells participating in a series of events such as signaling, adherence and host parasite interactions. In this study we examined the role of...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-45138-7
更新日期：2019-06-13 00:00:00
abstract：:Recently a new diluted magnetic semiconductor, (Ba,K)(Zn,Mn)2As2 (BZA), with high Curie temperature was discovered, showing an independent spin and charge-doping mechanism. This makes BZA a promising material for spintronics devices. We report the successful growth of a BZA single crystal for the first time in this st...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-08394-z
更新日期：2017-11-03 00:00:00
abstract：:Recent reports regarding the re-emergence of parasite sensitivity to chloroquine call for a new consideration of this drug as an interesting complementary tool in malaria elimination efforts, given its good safety profile and long half-life. A randomized (2:1), single-blind, placebo-controlled trial was conducted in M...
journal_title：Scientific reports
pub_type： 杂志文章,随机对照试验
doi：10.1038/s41598-017-01365-4
更新日期：2017-05-02 00:00:00
abstract：:The biodosimetric information is critical for evaluating the human health hazards caused by radon and its progeny. Here, we demonstrated that the formation of phosphorylated histone variant H2AX (γ-H2AX), p53-binding protein 1 (53BP1) and phosphorylated KRAB-associated protein 1 (pKAP-1) foci and their linear tracks i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep38295
更新日期：2016-12-06 00:00:00
abstract：:The ability to observe chemical reactions at the molecular level convincingly demonstrates the physical and chemical phenomena occurring throughout a reaction mechanism. Videos obtained through in situ transmission electron microscopy (TEM) revealed the oxidation of catalytic soot under practical reaction conditions. ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep10161
更新日期：2015-07-08 00:00:00
abstract：:The primary motor cortex (M1) is highly influenced by premotor/motor areas both within and across hemispheres. Dual site transcranial magnetic stimulation (dsTMS) has revealed interhemispheric interactions mainly at early latencies. Here, we used dsTMS to systematically investigate long-latency causal interactions bet...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-13708-2
更新日期：2017-11-02 00:00:00
abstract：:The p53 protein is a key mediator of the cellular response to various stress signals. In response to DNA damage, the concentration of p53 can temporally oscillate with fluctuations in both the amplitude and period. The underlying mechanism for p53 variability is not fully understood. Here, we construct a core regulato...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-41904-9
更新日期：2019-04-10 00:00:00
abstract：:Bivalent (poised or paused) chromatin comprises activating and repressing histone modifications at the same location. This combination of epigenetic marks at promoter or enhancer regions keeps genes expressed at low levels but poised for rapid activation. Typically, DNA at bivalent promoters is only lowly methylated i...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep37393
更新日期：2016-11-23 00:00:00
abstract：:Aluminum-based quasicrystals typically form across narrow composition ranges within binary to quaternary alloys, which makes their fabrication and characterization challenging. Here, we use combinatorial approaches together with fast characterization techniques to study a wide compositional range including known quasi...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-43666-w
更新日期：2019-05-09 00:00:00
abstract：:Tumor aggressiveness is usually associated with metastasis. MDA-MB 231, a triple-negative breast cancer (TNBC), is an aggressive type of breast cancer and associated with early metastasis. The Rho/ROCK pathway is a key regulator of cell motility involving cytoskeleton regulation through stabilization of actin filament...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-14216-z
更新日期：2017-10-20 00:00:00
abstract：:Highly selective hydrogenative carbon-carbon bond scission of biomass-derived platform oxygenates was achieved with a cerium oxide-supported ruthenium nanoparticle catalyst in water. The present catalyst enabled the selective cleavage of carbon-carbon σ bonds adjacent to carboxyl, ester, and hydroxymethyl groups, open...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-14373-1
更新日期：2017-10-25 00:00:00
abstract：:The ecosystem of the Source Region of Yangtze River (SRYR) is highly susceptible to climate change. In this study, the spatial-temporal variation of NPP from 2000 to 2014 was analyzed, using outputs of Carnegie-Ames-Stanford Approach model. Then the correlation characteristics of NPP and climatic factors were evaluate...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-020-80494-9
更新日期：2021-01-14 00:00:00
abstract：:Leber congenital amaurosis (LCA) is a genetically and clinically heterogeneous disease, and represents the most severe form of inherited retinal dystrophy (IRD). The present study reports the mutation spectra and frequency of known LCA and IRD-associated genes in 34 Japanese families with LCA (including three families...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-018-26524-z
更新日期：2018-05-29 00:00:00
abstract：:A multi-angle light scattering (MALS) system, combined with chromatographic separation, directly measures the absolute molar mass, size and concentration of the eluate species. The measurement of these crucial properties in solution is essential in basic macromolecular characterization and all research and production ...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-017-09051-1
更新日期：2017-08-30 00:00:00
abstract：:Rapid and efficient processing of external information by the brain is vital to survival in a highly dynamic environment. The key channel humans use to exchange information is language, but the neural underpinnings of its processing are still not fully understood. We investigated the spatio-temporal dynamics of neural...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep26558
更新日期：2016-05-24 00:00:00
abstract：:Potassium (K+) channels shape the response properties of neurons. Although enormous progress has been made to characterize K+ channels in the primary auditory neurons, the molecular identities of many of these channels and their contributions to hearing in vivo remain unknown. Using a combination of RNA sequencing and...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/s41598-019-39119-z
更新日期：2019-02-22 00:00:00
abstract：:Propionibacterium freudenreichii, a dairy starter, can reach a population of almost 109 propionibacteria per gram in Swiss-type cheese at the time of consumption. Also consumed as a probiotic, it displays strain-dependent anti-inflammatory properties mediated by surface proteins that induce IL-10 in leukocytes. We sel...
journal_title：Scientific reports
pub_type： 杂志文章
doi：10.1038/srep46409
更新日期：2017-04-13 00:00:00
