Pancreatic Cancer Cell Exosome-Mediated Macrophage Reprogramming and the Role of MicroRNAs 155 and 125b2 Transfection using Nanoparticle Delivery Systems.

abstract：:Inner Mongolia cashmere goats, as an important part of animal husbandry production, play an important role in animal fiber industry. In recent years, scientific research has made a lot of explorations on the molecular regulation mechanism of hair follicle cycle growth, but few studies have been reported on the develop...

journal_title：Scientific reports

authors： Han W,Yang F,Wu Z,Guo F,Zhang J,Hai E,Shang F,Su R,Wang R,Wang Z,Liu Z,Zhao Y,Wang Z,Zhang Y,Li J

更新日期：2020-03-11 00:00:00

abstract：:Traumatic brain injury (TBI) is a frequent cause of chronic headache, fatigue, insomnia, hyperactivity, memory deficits, irritability and posttraumatic stress disorder. Recent evidence suggests beneficial effects of pro-cannabinoid treatments. We assessed in mice levels of endocannabinoids in association with the occu...

journal_title：Scientific reports

authors： Vogel A,Wilken-Schmitz A,Hummel R,Lang M,Gurke R,Schreiber Y,Schäfer MKE,Tegeder I

更新日期：2020-09-10 00:00:00

abstract：:This study aims to examine the long-term effect of adjuvant treatment in Korean Medicine (KM) clinics in ischemic stroke patients, using a national sample cohort from the National Health Insurance Service in Korea between 2010 and 2013. The National Health Insurance Service - National Sample Cohort database from 2002 ...

journal_title：Scientific reports

authors： Lee YS,Kwon S,Chae Y,Jang BH,Ko SG

更新日期：2018-01-26 00:00:00

abstract：:Clarifying the fundamental adsorption and diffusion process of CO2 on single crystal ZnO surfaces is critical in understanding CO2 activation and transformation over ZnO-based catalysts. By using ultrahigh vacuum-Fourier transform infrared spectroscopy (UHV-FTIRS), we observed the fine structures of CO2 vibrational ba...

journal_title：Scientific reports

authors： Cao Y,Yu M,Qi S,Wang T,Huang S,Hu S,Xu M,Yan S

更新日期：2017-03-06 00:00:00

abstract：:The Leading Edge Vortex (LEV) is a universal mechanism enhancing lift in flying organisms. LEVs, generally illustrated as a single vortex attached to the wing throughout the downstroke, have not been studied quantitatively in freely flying insects. Previous findings are either qualitative or from flappers and tethered...

journal_title：Scientific reports

authors： Johansson LC,Engel S,Kelber A,Heerenbrink MK,Hedenström A

更新日期：2013-11-20 00:00:00

abstract：:In using nanostructures to design solar thermal absorbers, computational methods, such as rigorous coupled-wave analysis and the finite-difference time-domain method, are often employed to simulate light-structure interactions in the solar spectrum. However, those methods require heavy computational resources and CPU ...

journal_title：Scientific reports

authors： Seo J,Jung PH,Kim M,Yang S,Lee I,Lee J,Lee H,Lee BJ

更新日期：2019-10-21 00:00:00

abstract：:Early detection of dementia in Parkinson disease is a prerequisite for preventive therapeutic approaches. Modified serpinA1 in cerebrospinal fluid (CSF) was suggested as an early biomarker for differentiation between Parkinson patients with (PDD) or without dementia (PD). Within this study we aimed to further explore ...

journal_title：Scientific reports

authors： Halbgebauer S,Nagl M,Klafki H,Haußmann U,Steinacker P,Oeckl P,Kassubek J,Pinkhardt E,Ludolph AC,Soininen H,Herukka SK,Wiltfang J,Otto M

更新日期：2016-05-17 00:00:00

abstract：:The discovery of circulating tumour DNA molecules created a paradigm shift in tumour biomarkers as predictors of recurrence. Non-invasive prenatal testing (NIPT) to detect circulating cell-free foetal DNA in maternal plasma is increasingly recognised as a valuable substitute to perceive foetal copy number variation (C...

journal_title：Scientific reports

authors： Nakabayashi M,Kawashima A,Yasuhara R,Hayakawa Y,Miyamoto S,Iizuka C,Sekizawa A

更新日期：2018-07-25 00:00:00

abstract：:Ultrafine-grained die-upset Nd-Fe-B magnets are of importance because they provide a wide researching space to redesign the textured structures. Here is presented a route to obtain a new die-upset magnet with substantially improved magnetic properties. After experiencing the optimized heat treatment, both the coercivi...

journal_title：Scientific reports

authors： Wang Z,Ju J,Wang J,Yin W,Chen R,Li M,Jin C,Tang X,Lee D,Yan A

更新日期：2016-12-06 00:00:00

abstract：:This study aims to investigate the relation between vaginal microbiota and exposition to intra-amniotic inflammation (IAI). We conducted a prospective cohort study in women with preterm labor <34 weeks who had undergone amniocentesis to rule out IAI. Vaginal samples were collected after amniocentesis. Women with IAI i...

journal_title：Scientific reports

authors： Cobo T,Vergara A,Collado MC,Casals-Pascual C,Herreros E,Bosch J,Sánchez-García AB,López-Parellada R,Ponce J,Gratacós E

更新日期：2019-12-12 00:00:00

abstract：:In this paper we report for the first time an n-type carbon nanotube field effect transistor which is air- and water-stable, a necessary requirement for electrolyte gated CMOS circuit operation. The device is obtained through a simple process, where the native p-type transistor is converted to an n-type. This conversi...

journal_title：Scientific reports

authors： Joshi S,Bhatt VD,Jaworska E,Michalska A,Maksymiuk K,Becherer M,Gagliardi A,Lugli P

更新日期：2018-07-30 00:00:00

abstract：:The sequential paradigm of data acquisition and analysis in next-generation sequencing leads to high turnaround times for the generation of interpretable results. We combined a novel real-time read mapping algorithm with fast variant calling to obtain reliable variant calls still during the sequencing process. Thereby...

journal_title：Scientific reports

authors： Loka TP,Tausch SH,Renard BY

更新日期：2019-11-11 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Yan Y,Scott MJ

更新日期：2020-04-20 00:00:00

abstract：:The interaction between the T cell antigen receptor (TCR) and antigenic peptide in complex with major histocompatibility complex (MHC) molecules is a crucial step in T cell activation. The relative contributions of TCR:peptide and TCR:MHC contacts to the overall binding energy remain unclear. This has important implic...

journal_title：Scientific reports

authors： Zhang H,Lim HS,Knapp B,Deane CM,Aleksic M,Dushek O,van der Merwe PA

更新日期：2016-10-13 00:00:00

abstract：:The ability to predict the magnitude of an earthquake caused by deep fluid injections is an important factor for assessing the safety of the reservoir storage and the seismic hazard. Here, we propose a new approach to evaluate the seismic energy released during fluid injection by integrating injection parameters, indu...

journal_title：Scientific reports

authors： De Barros L,Cappa F,Guglielmi Y,Duboeuf L,Grasso JR

更新日期：2019-03-21 00:00:00

abstract：:Tsunamis can propagate thousands of kilometres across the ocean. Precise calculations of arrival times are essential for reliable early warning systems, determination of source and earth properties using the inverse problem, and time series modulation due to frequency dependency of phase speed. Far field observatories...

journal_title：Scientific reports

authors： Abdolali A,Kadri U,Kirby JT

更新日期：2019-11-14 00:00:00

abstract：:In eye movement perimetry (EMP), the saccadic reaction time (SRT) to 'seen' visual stimuli are delayed in glaucoma. Evaluating SRT behaviour in hemi-field sectors could refine its clinical implication. The development phase included 60 controls retrospectively and for the test cohort in evaluation phase, another 30 he...

journal_title：Scientific reports

authors： Mazumdar D,Meethal NSK,George R,Pel JJM

更新日期：2021-01-29 00:00:00

abstract：:The Schumann Resonances (ScR) are Extremely Low Frequency (ELF) electromagnetic resonances in the Earth-ionosphere cavity excited by global lightning discharges. This natural electromagnetic noise has likely existed on the Earth ever since the Earth had an atmosphere and an ionosphere, hence surrounding us throughout ...

journal_title：Scientific reports

authors： Elhalel G,Price C,Fixler D,Shainberg A

更新日期：2019-02-07 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Ribeiro MBT,Guzzoni V,Hord JM,Lopes GN,de Cássia Marqueti R,de Andrade RV,Selistre-de-Araujo HS,Durigan JLQ

更新日期：2019-04-17 00:00:00

abstract：:Elevated ground-level ozone (O3), which is an important aspect of air quality related to public health, has been causing increasing concern. This study investigated the spatiotemporal distribution of ground-level O3 concentrations in China using a dataset from the Chinese national air quality monitoring network during...

journal_title：Scientific reports

authors： Wang WN,Cheng TH,Gu XF,Chen H,Guo H,Wang Y,Bao FW,Shi SY,Xu BR,Zuo X,Meng C,Zhang XC

更新日期：2017-06-16 00:00:00

abstract：:Angiogenesis plays a key role in several diseases including cancer, ischemic vascular disease, and Alzheimer's disease. Chemical genetic screening of endothelial tube formation provides a robust approach for identifying signalling components that impact microvascular network morphology as well as endothelial cell biol...

journal_title：Scientific reports

authors： Sailem HZ,Al Haj Zen A

更新日期：2020-08-14 00:00:00

abstract：:Connectivity is fundamentally important for shaping the resilience of complex human and natural networks when systems are disturbed. Ecosystem resilience is, in part, shaped by the spatial arrangement of habitats, the permeability and fluxes between them, the stabilising functions performed by organisms, their dispers...

journal_title：Scientific reports

authors： Pearson RM,Schlacher TA,Jinks KI,Olds AD,Brown CJ,Connolly RM

更新日期：2021-01-13 00:00:00

abstract：:Most lysosomal storage disorders affect the central nervous system. However, lysosomal enzymes do not cross the blood-brain barrier (BBB), and intravenous enzyme infusion is not effective for the brain. Lysosomal enzymes can be re-engineered for BBB transport as IgG-enzyme fusion proteins, where the IgG domain is a mo...

journal_title：Scientific reports

authors： Boado RJ,Lu JZ,Hui EK,Lin H,Pardridge WM

更新日期：2019-12-09 00:00:00

abstract：:In this work, we apply homodyne detection to investigate the frequency-resolved photon statistics of a cw light field emitted by a driven-dissipative semiconductor system in real time. We demonstrate that studying the frequency dependence of the photon number noise allows us to distinguish intrinsic noise properties o...

journal_title：Scientific reports

authors： Lüders C,Aßmann M

更新日期：2020-12-29 00:00:00

abstract：:We present detailed investigations on single crystals of quaternary EuRhAl4Si2 and EuIrAl4Si2. The two compounds order antiferromagnetically at TN1 = 11.7 and 14.7 K, respectively, each undergoing two magnetic transitions. The magnetic properties in the ordered state present a large anisotropy despite Eu(2+)being an S...

journal_title：Scientific reports

authors： Maurya A,Thamizhavel A,Dhar SK,Bonville P

更新日期：2015-07-09 00:00:00

abstract：:Climate change is expected to have profound, partly unforeseeable effects on the composition of functional traits of complex ecosystems, such as coral reefs, and some ecosystem properties are at risk of disappearing. This study applies a novel spatially explicit, individual-based model to explore three critical life h...

journal_title：Scientific reports

authors： Kubicek A,Breckling B,Hoegh-Guldberg O,Reuter H

更新日期：2019-03-06 00:00:00

abstract：:The aberrant accumulation of ubiquitinated protein aggregates in cells plays a critical role in the pathogenesis of several degenerative diseases, including Parkinson disease (PD) and cystic fibrosis (CF). In this study, we found that Ras GTPase-activating protein-binding protein 1 (G3BP1) inhibits ubiquitinated prote...

journal_title：Scientific reports

authors： Anisimov S,Takahashi M,Kakihana T,Katsuragi Y,Kitaura H,Zhang L,Kakita A,Fujii M

更新日期：2019-09-09 00:00:00

abstract：:Crystallization is the bottleneck in macromolecular crystallography; even when a protein crystallises, crystal packing often influences ligand-binding and protein-protein interaction interfaces, which are the key points of interest for functional and drug discovery studies. The human hypoxia-inducible factor prolyl hy...

journal_title：Scientific reports

authors： Chowdhury R,Abboud MI,McAllister TE,Banerji B,Bhushan B,Sorensen JL,Kawamura A,Schofield CJ

更新日期：2020-12-15 00:00:00

abstract：:Physical activity (PA) is known to influence cognitive function. However, the impact of PA on patients with cerebrovascular disease (CVD) has not yet been elucidated. PA and cognitive function have not been measured simultaneously over time, which makes it difficult to evaluate their relationship. The purpose of this ...

journal_title：Scientific reports

authors： Kojima M,Nagano A

更新日期：2019-03-07 00:00:00

abstract：:In a short nanobearing system made from carbon nanotubes, the rotor with high rotational frequency may escape from the stator, which may cause a stability problem to the system of a nanodevice with such a nanobearing. In the present work, nanobearings with tri-walled nanotubes are investigated to reveal the conditions...

journal_title：Scientific reports

authors： Shi J,Liu LN,Cai K,Qin QH

更新日期：2017-07-28 00:00:00