Massively parallel sequencing of cell-free DNA in plasma for detecting gynaecological tumour-associated copy number alteration.

abstract：:We describe how an ensemble of four-level atoms in the diamond-type configuration can be applied to create a fully controllable effective coupling between two cavity modes. The diamond-type configuration allows one to use a bimodal cavity that supports modes of different frequencies or different circular polarisations...

journal_title：Scientific reports

authors： Chimczak G,Bartkiewicz K,Ficek Z,Tanaś R

更新日期：2018-10-03 00:00:00

abstract：:Decreasing egg quality following oocyte ageing is a major restricting factor for the breeding programs. The mechanisms behind this process has not yet been clarified. To examine the possible involvement of oxidative stress in the oocyte ageing process, the relative mRNA abundance of specific transcripts were determine...

journal_title：Scientific reports

authors： Samarin AM,Samarin AM,Østbye TK,Ruyter B,Sampels S,Burkina V,Blecha M,Policar T

更新日期：2019-07-18 00:00:00

abstract：:We reconstructed the radiological dose for birds observed at 300 census sites in the 50-km northwest area affected by the accident at the Fukushima Daiichi nuclear power plant over 2011-2014. Substituting the ambient dose rate measured at the census points (from 0.16 to 31 μGy h(-1)) with the dose rate reconstructed f...

journal_title：Scientific reports

authors： Garnier-Laplace J,Beaugelin-Seiller K,Della-Vedova C,Métivier JM,Ritz C,Mousseau TA,Møller AP

更新日期：2015-11-16 00:00:00

abstract：:Gamma-glutamyl hydroxymethyl rhodamine green (gGlu-HMRG) is an activatable fluorescent probe that can be activated by γ-glutamyltranspeptidase (GGT). The expression of GGT in the kidney, which is one of the major organs exhibiting enhanced GGT expression, is exclusively localised to the cortex. Here, we aimed to inves...

journal_title：Scientific reports

authors： Iyama T,Takata T,Yamada K,Mae Y,Taniguchi S,Ida A,Ogawa M,Yamamoto M,Hamada S,Fukuda S,Kanda T,Sugihara T,Isomoto H,Urano Y

更新日期：2020-07-21 00:00:00

abstract：:Cells in vascular walls are exposed to blood pressure variability (BPV)-induced cycle-by-cycle fluctuations in mechanical forces which vary considerably with pathology. For example, BPV is elevated in hypertension but reduced under anesthesia. We hypothesized that the extent of mechanical fluctuations applied to vascu...

journal_title：Scientific reports

authors： Bartolák-Suki E,Suki B

更新日期：2020-01-15 00:00:00

abstract：:The nonsynonymous SCN10A single nucleotide polymorphism (SNP) rs6795970 has been reported to associate with PR interval and atrial fibrillation (AF) and in strong linkage disequilibrium (LD) with the AF-associated SNP rs6800541. In this study, we investigated whether rs6795970 polymorphisms are associated with AF recu...

journal_title：Scientific reports

authors： Wu H,Xu J,Chen S,Zhou G,Qi B,Wei Y,Hu E,Tang D,Chen G,Li H,Zhao L,Shi Y,Liu S

更新日期：2017-03-10 00:00:00

abstract：:Few studies have investigated the relationship between chronic rhinosinusitis (CRS) and erectile dysfunction (ED). This case-control study aimed to investigate the association between CRS and the risk of ED in a large national sample. Tapping Taiwan's National Health Insurance Research Database, we identified people 3...

journal_title：Scientific reports

authors： Tai SY,Wang LF,Tai CF,Huang YT,Chien CY

更新日期：2016-08-31 00:00:00

abstract：:Chronic wounds affect millions of patients around the world and their treatment is challenging as the early signs indicating their development are subtle. In addition, a type of chronic wound, known as pressure ulcer, develops in patients with limited mobility. Infection and frequent bleeding are indicators of chronic...

journal_title：Scientific reports

authors： Farooqui MF,Shamim A

更新日期：2016-06-29 00:00:00

abstract：:Insecticides and other agrochemicals have become indispensable components of the agricultural system to ensure a notable increase in crop yield and food production. As a natural consequence, chemical residues result in significantly increased contamination of both terrestrial and aquatic ecosystems. The present study ...

journal_title：Scientific reports

authors： Basal WT,Ahmed ART,Mahmoud AA,Omar AR

更新日期：2020-11-11 00:00:00

abstract：:Networks are a powerful abstraction with applicability to a variety of scientific fields. Models explaining their morphology and growth processes permit a wide range of phenomena to be more systematically analysed and understood. At the same time, creating such models is often challenging and requires insights that ma...

journal_title：Scientific reports

authors： Menezes T,Roth C

更新日期：2014-09-05 00:00:00

abstract：:Sweet potato leaf curl virus (SPLCV) causes yield losses in sweet potato cultivation. Diagnostic techniques such as serological detection have been developed because these plant viruses are difficult to treat. Serological assays have been used extensively with recombinant antibodies such as whole immunoglobulin or sin...

journal_title：Scientific reports

authors： Cho SH,Kil EJ,Cho S,Byun HS,Kang EH,Choi HS,Lee MG,Lee JS,Lee YG,Lee S

更新日期：2020-05-15 00:00:00

abstract：:We tested the hypothesis that epigenetic mechanisms in the brain and the immune system are associated with chronic pain. Genome-wide DNA methylation assessed in 9 months post nerve-injury (SNI) and Sham rats, in the prefrontal cortex (PFC) as well as in T cells revealed a vast difference in the DNA methylation landsca...

journal_title：Scientific reports

authors： Massart R,Dymov S,Millecamps M,Suderman M,Gregoire S,Koenigs K,Alvarado S,Tajerian M,Stone LS,Szyf M

更新日期：2016-01-28 00:00:00

abstract：:Metal sulfides are of great interest for future electrode materials in supercapacitor and solar cell applications owing to their superior electrochemical activity and excellent electrical conductivity. With this scope, a binary transition metal sulfide (CoS) is prepared via one-step hydrothermal synthesis. Hexagonal p...

journal_title：Scientific reports

authors： Ashok Kumar K,Pandurangan A,Arumugam S,Sathiskumar M

更新日期：2019-02-04 00:00:00

abstract：:Although poaching (illegal killing) is an important cause of death for large carnivores globally, the effect of lethal management policies on poaching is unknown for many populations. Two opposing hypotheses have been proposed: liberalizing killing may decrease poaching incidence ('tolerance hunting') or increase it (...

journal_title：Scientific reports

authors： Santiago-Ávila FJ,Chappell RJ,Treves A

更新日期：2020-08-17 00:00:00

abstract：:There a few reports of rhodamine-based fluorescent sensors for selective detection of only Al3+, due to the challenge of identifying a suitable ligand for binding Al3+ ion. The use of fluorophore moieties appended to a polymer backbone for sensing applications is far from mature. Here, we report a new fluorescent prob...

journal_title：Scientific reports

authors： Gandra UR,Courjaret R,Machaca K,Al-Hashimi M,Bazzi HS

更新日期：2020-11-11 00:00:00

abstract：:The aim of this study was to identify genes for which the expression within carotid atherosclerosis was reproducibly associated with the symptoms of cerebral embolization. Two publically available microarray datasets E-MEXP-2257 and GSE21545 were analysed using GeneSpring 11.5. The two datasets utilized a total of 22 ...

journal_title：Scientific reports

authors： Biros E,Moran CS,Maguire J,Holliday E,Levi C,Golledge J

更新日期：2017-06-28 00:00:00

abstract：:Assembly of metagenomic samples is a very complex process, with algorithms designed to address sequencing platform-specific issues, (read length, data volume, and/or community complexity), while also faced with genomes that differ greatly in nucleotide compositional biases and in abundance. To address these issues, we...

journal_title：Scientific reports

authors： Scholz M,Lo CC,Chain PS

更新日期：2014-10-01 00:00:00

abstract：:A growing interest in healthy eating has lead to an increase in the consumption of vegetables, associated with a rising number of bacterial outbreaks related to fresh produce. This is the case of the outbreak in Germany, caused by a O104:H4 enteroaggregative E. coli strain lysogenic for a Stx phage. Temperate Stx phag...

journal_title：Scientific reports

authors： Quirós P,Muniesa M

更新日期：2017-08-10 00:00:00

abstract：:In this study, we propose a novel sensitive solid-based immunosensor developed on a plasmonic nanopaper platform for the detection of Escherichia coli (E. coli) bacteria. This plasmonic nanopaper that comprises of carboxylated bacterial cellulose (CBC) impregnated with gold nanoparticles (AuNP-CBC), employed as a quen...

journal_title：Scientific reports

authors： Heli B,Ajji A

更新日期：2020-09-01 00:00:00

abstract：:Polymer derived ceramic (PDC) composite coatings were deposited on AISI 304 substrates using siloxane based preceramic polymer polymethlysilsquioxane (PMS) and ZrSi2 as active filler or Ag as passive filler. The tribological performance of the composite coatings was evaluated at room temperature and moderately high te...

journal_title：Scientific reports

authors： Alvi SA,Akhtar F

更新日期：2018-10-10 00:00:00

abstract：:Performing everyday actions requires fine postural control, which is a major focus of functional rehabilitation programs. Among the various range of training methods likely to improve balance and postural stability, motor imagery practice (MIP) yielded promising results. Transcranial direct current stimulation (tDCS) ...

journal_title：Scientific reports

authors： Saruco E,Di Rienzo F,Nunez-Nagy S,Rubio-Gonzalez MA,Jackson PL,Collet C,Saimpont A,Guillot A

更新日期：2017-03-28 00:00:00

abstract：:Tolmetin is a non-steroidal anti-inflammatory drug being used to decrease the level of hormones which are the reasons for pain, swelling, tiredness, and stiffness for osteoarthritis and rheumatoid arthritis cases. We evaluated its solubility in supercritical carbon dioxide (SC-CO2) with the aim of drug nanonization, c...

journal_title：Scientific reports

authors： Pishnamazi M,Zabihi S,Sarafzadeh P,Borousan F,Marjani A,Pelalak R,Shirazian S

更新日期：2020-11-11 00:00:00

abstract：:Emergence of resistant Plasmodium species makes drug efficacy testing a crucial part of malaria control. Here we describe a novel assay for sensitive, fast and simple drug screening via the magneto-optical detection of hemozoin, a natural biomarker formed during the hemoglobin metabolism of Plasmodium species. By quan...

journal_title：Scientific reports

authors： Molnár P,Orbán Á,Izrael R,Babai R,Marton L,Butykai Á,Karl S,Vértessy BG,Kézsmárki I

更新日期：2020-08-20 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Alam MK,Zheng L,Liu R,Papagerakis S,Papagerakis P,Geyer CR

更新日期：2020-09-09 00:00:00

abstract：:Communication between neurons involves presynaptic neurotransmitter release which can be evoked by action potentials or occur spontaneously as a result of stochastic vesicle fusion. The Ca2+-binding double C2 proteins Doc2a and -b were implicated in spontaneous and asynchronous evoked release, but the mechanism remain...

journal_title：Scientific reports

authors： Bourgeois-Jaarsma Q,Verhage M,Groffen AJ

更新日期：2019-10-08 00:00:00

abstract：:The mode of action for oncolytic viruses (OVs) in cancer treatment is thought to depend on a direct initial cytotoxic effect against infected tumor cells and subsequent activation of immune cell responses directed against the neoplasm. To study both of these effects in a mouse model of glioblastoma (GBM), we employed ...

journal_title：Scientific reports

authors： Alayo QA,Ito H,Passaro C,Zdioruk M,Mahmoud AB,Grauwet K,Zhang X,Lawler SE,Reardon DA,Goins WF,Fernandez S,Chiocca EA,Nakashima H

更新日期：2020-03-20 00:00:00

abstract：:Pachychoroid spectrum diseases have attracted increasing attention, though their pathophysiology has yet to be fully elucidated. In this study, we assessed the vascular diameters of vortex veins in pachychoroid spectrum diseases such as central serous chorioretinopathy (CSC), pachychoroid neovasculopathy without polyp...

journal_title：Scientific reports

authors： Matsumoto H,Hoshino J,Arai Y,Mukai R,Nakamura K,Kikuchi Y,Kishi S,Akiyama H

更新日期：2020-11-11 00:00:00

abstract：:Saponins represent a promising class of vaccine adjuvant. Together with the TLR4-ligand MPL, QS-21 is part of the Adjuvant System AS01, a key component of the malaria and zoster candidate vaccines that display demonstrated clinical efficacy. However, the mechanism of action of QS-21 in this liposomal formulation is po...

journal_title：Scientific reports

authors： Detienne S,Welsby I,Collignon C,Wouters S,Coccia M,Delhaye S,Van Maele L,Thomas S,Swertvaegher M,Detavernier A,Elouahabi A,Goriely S,Didierlaurent AM

更新日期：2016-12-20 00:00:00

abstract：:The colon can have an absorptive function similar to that of the small intestine after the massive resection of the small bowel. To improve colonic absorptive function, we created a valve in the colon (artificial colonic valve, ACV). ACVs were created in 20 rats that had 80 percent of their small intestine resected, w...

journal_title：Scientific reports

authors： Deng G,Deng Z

更新日期：2020-01-21 00:00:00

abstract：:Brain hypometabolism is a common epilepsy-related finding in both patients and animal models. Fluorodeoxyglucose positron emission tomography studies have shown that recurrent seizures lead to reduced glucose metabolism in certain brain regions, but no studies have definitively determined whether this induces epilepto...

journal_title：Scientific reports

authors： Zhang H,Gao G,Zhang Y,Sun Y,Li H,Dong S,Ma W,Liu B,Wang W,Wu H,Zhang H

更新日期：2017-07-19 00:00:00