Genomic and metagenomic signatures of giant viruses are ubiquitous in water samples from sewage, inland lake, waste water treatment plant, and municipal water supply in Mumbai, India.

abstract：:Nanostructured (NS) and ultrafine-grained (UFG) materials have high strength and relatively low ductility. Their toughness has not been comprehensively investigated. Here we report the Charpy impact behavior and the corresponding microstructural evolutions in UFG Cu with equi-axed and elongated grains which were prepa...

journal_title：Scientific reports

authors： Liang N,Zhao Y,Wang J,Zhu Y

更新日期：2017-03-17 00:00:00

abstract：:Long-read sequencing technologies such as Pacific Biosciences and Oxford Nanopore MinION are capable of producing long sequencing reads with average fragment lengths of over 10,000 base-pairs and maximum lengths reaching 100,000 base- pairs. Compared with short reads, the assemblies obtained from long-read sequencing ...

journal_title：Scientific reports

authors： Giordano F,Aigrain L,Quail MA,Coupland P,Bonfield JK,Davies RM,Tischler G,Jackson DK,Keane TM,Li J,Yue JX,Liti G,Durbin R,Ning Z

更新日期：2017-06-21 00:00:00

abstract：:Herbicide resistance has been observed in Chloris truncata, an Australian native C4 grass and a summer-fallow weed, which is common in no-till agriculture situations where herbicides are involved in crop management. To investigate the role of drought and increased atmospheric carbon dioxide (CO2) in determining weed g...

journal_title：Scientific reports

authors： Weller SL,Florentine SK,Mutti NK,Jha P,Chauhan BS

更新日期：2019-07-24 00:00:00

abstract：:The enhancement and control of non-linear phenomena at a nanometer scale has a wide range of applications in science and in industry. Among these phenomena, high-harmonic generation in solids is a recent focus of research to realize next generation petahertz optoelectronic devices or compact all solid state EUV source...

journal_title：Scientific reports

authors： Franz D,Kaassamani S,Gauthier D,Nicolas R,Kholodtsova M,Douillard L,Gomes JT,Lavoute L,Gaponov D,Ducros N,Février S,Biegert J,Shi L,Kovacev M,Boutu W,Merdji H

更新日期：2019-04-05 00:00:00

abstract：:Gibberellins (GAs) participate in controlling various aspects of basic plant growth responses. With the exception of bryophytes, GA signalling in land plants, such as lycophytes, ferns and angiosperms, is mediated via GIBBERELLIN-INSENSITIVE DWARF1 (GID1) and DELLA proteins. To explore whether this GID1-DELLA mechanis...

journal_title：Scientific reports

authors： Du R,Niu S,Liu Y,Sun X,Porth I,El-Kassaby YA,Li W

更新日期：2017-11-30 00:00:00

abstract：:Identifying the occurrence mechanism of drug-induced side effects (SEs) is critical for design of drug target and new drug development. The expression of genes in biological processes is regulated by transcription factors(TFs) and/or microRNAs. Most of previous studies were focused on a single level of gene or gene se...

journal_title：Scientific reports

authors： Jia X,Jin Q,Liu X,Bian X,Wang Y,Liu L,Ma H,Tan F,Gu M,Chen X

更新日期：2017-07-20 00:00:00

abstract：:The entire recrystallisation sequence and associated crystallographic texture evolution of Mg-0.8Zn-0.2Ca (wt.%) alloy was tracked using a quasi-in-situ electron backscatter diffraction (EBSD) method. Characteristic "Rare Earth" (RE) texture was formed, originating mainly from double twins and twinning-related shear b...

journal_title：Scientific reports

authors： Guan D,Liu X,Gao J,Ma L,Wynne BP,Rainforth WM

更新日期：2019-05-09 00:00:00

abstract：:Enhanced and immediate expression of cyclooxygenase-2 (COX-2) mRNA is observed in IL-1β-stimulated OA chondrocytes but the synthesis of protein found significantly delayed. Here we investigated the role of stress granules (SGs), ribonucleoprotein complexes that regulate mRNA translation, in the delayed translation of ...

journal_title：Scientific reports

authors： Ansari MY,Haqqi TM

更新日期：2016-06-08 00:00:00

abstract：:Grazing and burrowing organisms usually homogenise microalgal mats that form on benthic sediments of many aquatic ecosystems. In the absence of this disruption, microalgal mats can accrete laminated deposits (stromatolites). Stromatolites are rare in modern coastal ecosystems, but persist at locations where metazoans ...

journal_title：Scientific reports

authors： Rishworth GM,Perissinotto R,Bird MS,Strydom NA,Peer N,Miranda NA,Raw JL

更新日期：2017-02-16 00:00:00

abstract：:Previous studies have shown that CD61 (integrin-β3) promotes the differentiation of human umbilical cord mesenchymal stem cells (hUC-MSCs) into germ-like cells. However, the mechanism remains unclear. In this study, we showed that overexpression of CD61 in canine adipose-derived mesenchymal stem cells (cADMSCs) promot...

journal_title：Scientific reports

authors： Fang J,Wei Y,Lv C,Peng S,Zhao S,Hua J

更新日期：2017-03-03 00:00:00

abstract：:Iron oxide nanoparticles have attracted a great deal of research interest and have been widely used in bioscience and clinical research including as contrast agents for magnetic resonance imaging, hyperthermia and magnetic field assisted radionuclide therapy. It is therefore important to develop methods, which can pro...

journal_title：Scientific reports

authors： Erofeev A,Gorelkin P,Garanina A,Alova A,Efremova M,Vorobyeva N,Edwards C,Korchev Y,Majouga A

更新日期：2018-05-10 00:00:00

abstract：:In this study we uncovered, through targeted ablation, a potential role for corticospinal, cerebello-rubro-spinal, and hypothalamic A11 dopaminergic systems in the development of restless legs syndrome (RLS)-like movements during sleep. Targeted lesions in select basal ganglia (BG) structures also revealed a major rol...

journal_title：Scientific reports

authors： Guo CN,Yang WJ,Zhan SQ,Yang XF,Chen MC,Fuller PM,Lu J

更新日期：2017-08-29 00:00:00

abstract：:The clinical application of dihydroartemisinin (DHA) has been hampered due to its poor water-solubility. To overcome this hurdle, we devised a novel polymer-drug conjugate, multiarm polyethylene glycol-dihydroartemisinin (PEG-DHA), made by linking DHA with multiarm polyethylene glycol. Herein, we investigated PEG-DHA ...

journal_title：Scientific reports

authors： Dai L,Wang L,Deng L,Liu J,Lei J,Li D,He J

更新日期：2014-07-29 00:00:00

abstract：:Humans have an innate set of emotions recognised universally. However, emotion recognition also depends on socio-cultural rules. Although adults recognise vocal emotions universally, they identify emotions more accurately in their native language. We examined developmental trajectories of universal vocal emotion recog...

journal_title：Scientific reports

authors： Chronaki G,Wigelsworth M,Pell MD,Kotz SA

更新日期：2018-06-14 00:00:00

abstract：:The use of misidentified cell lines contaminated by other cell lines and/or microorganisms has generated much confusion in the scientific literature. Detailed characterization of such contaminations is therefore crucial to avoid misinterpretation and ensure robustness and reproducibility of research. Here we use DNA-s...

journal_title：Scientific reports

authors： Loiseau V,Cordaux R,Giraud I,Beby-Defaux A,Lévêque N,Gilbert C

更新日期：2020-09-29 00:00:00

abstract：:Ichthyoarchaeological evidence is uncommon at ancient hunter-gatherer sites from various regions and timeframes. This research contributes to the development of microarchaeological techniques useful for identifying fishing economies in situations where classifiable bones are unavailable. Specifically, traces of heat a...

journal_title：Scientific reports

authors： Butler DH,Shahack-Gross R

更新日期：2017-06-15 00:00:00

abstract：:Minimum toe clearance (MTC) occurs during a highly dynamic phase of the gait cycle and is associated with the highest risk of unintentional contact with obstacles or the ground. Age, cognitive function, attention and visual feedback affect foot clearance but how these factors interact to influence MTC control is not f...

journal_title：Scientific reports

authors： Killeen T,Easthope CS,Demkó L,Filli L,Lőrincz L,Linnebank M,Curt A,Zörner B,Bolliger M

更新日期：2017-05-15 00:00:00

abstract：:The role of Toll-like receptor-2 (TLR2) in radio-resistance remained largely unknown. TLR2 knockout (TLR2(-/-)) mice received radiation of 6.5 Gy, and then were studied. We found that radiation resulted in more severe mortality and morbidity rates in TLR2(-/-) mice. The cause of death in TLR2(-/-) mice may be severe a...

journal_title：Scientific reports

authors： Gao F,Zhang C,Zhou C,Sun W,Liu X,Zhang P,Han J,Xian L,Bai D,Liu H,Cheng Y,Li B,Cui J,Cai J,Liu C

更新日期：2015-08-13 00:00:00

abstract：:Rice black-streaked dwarf disease, caused by rice black-streaked dwarf virus (RBSDV), is transmitted by small brown planthoppers (Laodelphax striatellus Fallén, SBPH) and causes severe yield loss in epidemic years in China and other East Asian countries. Breeding for resistance to RBSDV is a promising strategy to cont...

journal_title：Scientific reports

authors： Zhou T,Du L,Wang L,Wang Y,Gao C,Lan Y,Sun F,Fan Y,Wang G,Zhou Y

更新日期：2015-07-22 00:00:00

abstract：:Influenza infection represents a major socio-economic burden worldwide. Novel delivery methods can render influenza vaccination easier and more acceptable by the public, and importantly confer protection equal or superior to that induced by conventional systemic administration. An attractive target for vaccine deliver...

journal_title：Scientific reports

authors： Koutsonanos DG,Vassilieva EV,Stavropoulou A,Zarnitsyn VG,Esser ES,Taherbhai MT,Prausnitz MR,Compans RW,Skountzou I

更新日期：2012-01-01 00:00:00

abstract：:Cervical oesophageal cancer (CEC) is a relatively uncommon malignancy. The biological behaviour and treatment have not been well studied. This retrospective study reviewed the clinicopathological features of 28 patients with CEC who underwent surgical resection to investigate the biological behaviour, treatment and pr...

journal_title：Scientific reports

authors： Chen SB,Yang XH,Weng HR,Liu DT,Li H,Chen YP

更新日期：2017-06-12 00:00:00

abstract：:This work describes a simple technique to produce porous ceramics with aligned porosity having very high permeability and specific surface area. SiOC-based compositions were processed from blends of three types of preceramic polymer and a catalyst, followed by curing and pyrolysis. The heating applied from the bottom ...

journal_title：Scientific reports

authors： Vakifahmetoglu C,Zeydanli D,Innocentini MD,Ribeiro FD,Lasso PR,Soraru GD

更新日期：2017-01-20 00:00:00

abstract：:Amorphous solid dispersion (ASD) is a widely employed formulation technique for drugs with poor aqueous solubility. Polymers are integral components of ASDs, but mechanisms by which polymers lead to the generation and maintenance of supersaturated solutions, which enhance oral absorption in vivo, are poorly understood...

journal_title：Scientific reports

authors： Wilson VR,Lou X,Osterling DJ,Stolarik DF,Jenkins GJ,Nichols BLB,Dong Y,Edgar KJ,Zhang GGZ,Taylor LS

更新日期：2020-10-28 00:00:00

abstract：:TP53 mutation (i.e., loss of normal-p53) may evoke epithelial-mesenchymal transition (EMT), which was previously attributed to loss of certain miRNAs. However, not all epithelial cells undergo EMT upon TP53 mutation, and the p53-miRNA axis may not fully explain p53 function in epithelial integrity. We here show two mo...

journal_title：Scientific reports

authors： Oikawa T,Otsuka Y,Onodera Y,Horikawa M,Handa H,Hashimoto S,Suzuki Y,Sabe H

更新日期：2018-01-25 00:00:00

abstract：:The peptidoglycan of Staphylococcus aureus is highly amidated. Amidation of α-D-isoglutamic acid in position 2 of the stem peptide plays a decisive role in the polymerization of cell wall building blocks. S. aureus mutants with a reduced degree of amidation are less viable and show increased susceptibility to methicil...

journal_title：Scientific reports

authors： Nöldeke ER,Muckenfuss LM,Niemann V,Müller A,Störk E,Zocher G,Schneider T,Stehle T

更新日期：2018-08-28 00:00:00

abstract：:Although attempts have been made to reveal the relationships between bacteria and human health, little is known about the species and function of the microbial community associated with oral diseases. In this study, we report the sequencing of 16 metagenomic samples collected from dental swabs and plaques representing...

journal_title：Scientific reports

authors： Wang J,Qi J,Zhao H,He S,Zhang Y,Wei S,Zhao F

更新日期：2013-01-01 00:00:00

abstract：:Anatomically incomplete spinal cord injuries can be followed by functional recovery mediated, in part, by the formation of intraspinal detour circuits. Here, we show that adult mice recover tactile and proprioceptive function following a unilateral dorsal column lesion. We therefore investigated the basis of this reco...

journal_title：Scientific reports

authors： Granier C,Schwarting J,Fourli E,Laage-Gaupp F,Hennrich AA,Schmalz A,Jacobi A,Wesolowski M,Conzelmann KK,Bareyre FM

更新日期：2020-07-02 00:00:00

abstract：:Sufficient tissue oxygenation is required for regular brain function; thus oxygen supply must be tightly regulated to avoid hypoxia and irreversible cell damage. If hypoxia occurs the transcription factor complex hypoxia-inducible factor (HIF) will accumulate and coordinate adaptation of cells to hypoxia. However, eve...

journal_title：Scientific reports

authors： Kleszka K,Leu T,Quinting T,Jastrow H,Pechlivanis S,Fandrey J,Schreiber T

更新日期：2020-11-05 00:00:00

abstract：:Endothelin-1 (ET-1) is associated with endothelial dysfunction and vasoconstriction. Increased circulating ET-1 levels are associated with long-term cardiovascular mortality. Renalase, released from kidney, metabolizes catecholamines and regulates blood pressure. An increase in circulating renalase levels has been rep...

journal_title：Scientific reports

authors： Li YH,Sheu WH,Lee WJ,Wang J-,Fu CP,Liang KW,Lee IT

更新日期：2018-05-09 00:00:00

abstract：:Several carbon dots doping with diferent elements (Ca, Ag, Au) were fabricated and their catalytic properties had been investigated in this paper. It was found that the Ag-doped carbon dots (CDAg) had played a role of mimic enzyme on the reaction of HAuCl4-H2O2 and generated nanogold particles with surface enhanced Ra...

journal_title：Scientific reports

authors： Wang H,Huang X,Wen G,Jiang Z

更新日期：2019-07-10 00:00:00