Potential role of serum fetuin-A in relation with pro-inflammatory, chemokine and adhesion molecules in diabetic kidney disease: a case-control study.

abstract：:The purpose of this study is to investigate the effect of H2O2 on the aging of melanogenesis in human melanocytes. The staining of SA-β-galactosidase, an aging marker, was remarkably increased in the cells aged with H2O2 at 62.5 µM or more compared with young cells. The intracellular H2O2 level and melanin synthesis w...

journal_title：Molecular biology reports

authors： Ko H,Kim MM

更新日期：2019-04-01 00:00:00

abstract：:Inhibitor of growth protein 3 (ING3), a new member of ING family, is involved in the regulation of various processes. In this study, a full-length cDNA of ING3 (named as RpING3) was cloned from the gill of Ruditapes philippinarum by rapid amplification of cDNA ends method for the first time. The cDNA obtained was 1442...

journal_title：Molecular biology reports

authors： Hu GW,Yan XW,Qin YJ,Nie HT

更新日期：2014-06-01 00:00:00

abstract：:The cyclin-dependent kinases (CDKs) are a family of serine/threonine kinases, playing an essential role in regulating cell-cycle progression. In our present work, human CDK5 and a novel CDK5 splicing variant, named as CDK5-SV, were cloned from the cDNA library of human testis. CDK5-SV lacking the exon 7 of CDK5 encode...

journal_title：Molecular biology reports

authors： Li Q,Liu X,Zhang M,Ye G,Qiao Q,Ling Y,Wu Y,Zhang Y,Yu L

更新日期：2010-06-01 00:00:00

abstract：:Tumor microenvironment (TME) crucially functions in tumor initiation and progression. Stroma-tumor interactions and cellular transdifferentiation are the prerequisite for tumor formation. Transforming growth factor-β (TGF-β), a major cytokine secreted by tumor-associated fibroblasts (TAFs) and cancer cells, is a cruci...

journal_title：Molecular biology reports

authors： Wang XL,Huang C

更新日期：2019-06-01 00:00:00

abstract：:The majority of familial breast and ovarian cancers arise from mutations in the BRCA1 and BRCA2 genes. Amplification at the 11q13.5 locus is commonly observed in breast and ovarian cancers. In 2003, Hughes-Davies et al. identified a novel gene (EMSY) at this locus which binds BRCA2 within a region deleted in some canc...

journal_title：Molecular biology reports

authors： Altinisik J,Karateke A,Coksuer H,Ulutin T,Buyru N

更新日期：2011-01-01 00:00:00

abstract：:The mechanism by which external Bax releases cytochrome c is still controversial and may also depend on the type of mitochondria and the actual localisation of cytochrome c. Outer membrane porin acquires high binding affinity for hexokinase by interacting with the adenine nucleotide translocator (ANT) in the contact s...

journal_title：Molecular biology reports

authors： Vyssokikh MY,Zorova L,Zorov D,Heimlich G,Jürgensmeier JJ,Brdiczka D

更新日期：2002-01-01 00:00:00

abstract：:Obesity is for many scholars the most important starting status that gives rise to Metabolic Syndrome (MS) and Type 2 Diabetes (T2D). In the present paper, a genetically homogeneous Amerindian population, as defined by HLA genes, has been genotyped for one of the MS and T2D predisposing genes: PPAR-γ Ala12 and Pro 12 ...

journal_title：Molecular biology reports

authors： Arnaiz-Villena A,Fernández-Honrado M,Areces C,Enríquez-de-Salamanca M,Abd-El-Fatah-Khalil S,Coca C,Arribas I,Algora M,Rey D

更新日期：2013-02-01 00:00:00

abstract：:20S proteasomes are large (700 kDa) proteinase complexes which form the central catalytic core of larger complexes (26S proteasomes or PA28-20S complexes) formed by association with regulatory particles. These larger complexes are involved in diverse regulatory processes in the cell including cyclin breakdown, proteol...

journal_title：Molecular biology reports

authors： Bose S,Mason GG,Rivett AJ

更新日期：1999-04-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) could infect porcine alveolar macrophages (PAM), and the CD169 and CD163 are identified as critical receptors on the surface of PAM, but whether the single nucleotide polymorphisms (SNPs) of these genes could influence the infection is remain unclear. In this...

journal_title：Molecular biology reports

authors： Ren YW,Zhang YY,Affara NA,Sargent CA,Yang LG,Zhao JL,Fang LR,Wu JJ,Fang R,Tong Q,Xiao J,Li JL,Jiang YB,Chen HC,Zhang SJ

更新日期：2012-11-01 00:00:00

abstract：:Bone abnormalities as a consequence of osteoblast deregulation are associated with several diseases such as diabetes and chronic kidney disease. Important role for oxidized low density lipoproteins (oxLDL) in the pathophysiology of bone disorders has been reported. However, little is known about the effects and mechan...

journal_title：Molecular biology reports

authors： Dawodu D,Patecki M,Dumler I,Haller H,Kiyan Y

更新日期：2019-06-01 00:00:00

abstract：:One-third of all individuals with epilepsy are resistant to antiepileptic drug (AED) treatment. Antiepileptic treatment response has been suggested to be modulated by genetic polymorphisms of drug efflux transporters. Several polymorphic variants within the multidrug resistance 1 (MDR1) gene, which encodes the major t...

journal_title：Molecular biology reports

authors： Seven M,Batar B,Unal S,Yesil G,Yuksel A,Guven M

更新日期：2014-01-01 00:00:00

abstract：:Endometriosis is a polygenic and multifactorial gynecology situation which might be associated with angiogenesis. In the current study we assess the role of vascular endothelial growth factor (VEGF) - 2578 A/C, and + 936 C/T polymorphisms in susceptibility to endometriosis and checking the expression of VEGF mRNA in e...

journal_title：Molecular biology reports

authors： Rashidi BH,Sarhangi N,Aminimoghaddam S,Haghollahi F,Naji T,Amoli MM,Shahrabi-Farahani M

更新日期：2019-06-01 00:00:00

abstract：:The Rv3203 (LipV) of Mycobacterium tuberculosis (Mtb) H37Rv, is annotated as a member of Lip family based on the presence of characteristic consensus esterase motif ‘GXSXG’. In vitro culture studies of Mtb H37Ra indicated that expression of Rv3203 gene was up-regulated during acidic stress as compared to normal wherea...

journal_title：Molecular biology reports

authors： Singh G,Arya S,Narang D,Jadeja D,Singh G,Gupta UD,Singh K,Kaur J

更新日期：2014-01-01 00:00:00

abstract：:Olanzapine, an atypical antipsychotic medication, has been associated with weight gain and metabolic toxicity, especially in long term usage. Carnosic acid (CA), a major constituent of rosemary extract, has been shown to improve metabolic abnormalities. In this experiment, the effect of CA on olanzapine-induced obesit...

journal_title：Molecular biology reports

authors： Razavi BM,Abazari AR,Rameshrad M,Hosseinzadeh H

更新日期：2020-10-01 00:00:00

abstract：:The complete mitochondrial genome of Pseudochauhanea macrorchis was determined and compared with other monogenean mitochondrial genomes from GenBank. The circular genome was 15,031 bp in length and encoded 36 genes (12 protein-coding genes, two ribosomal RNAs, and 22 transfer RNAs) typically found in flatworms. Struct...

journal_title：Molecular biology reports

authors： Zhang J,Wu X,Xie M,Li A

更新日期：2012-08-01 00:00:00

abstract：:MicroRNAs (miRNAs) may play important roles in SLE, but genetic polymorphisms of miRNAs and their relationships with various autoantibodies present in SLE patients remain unclear. Here, we report that 213 SLE patients and 209 healthy individuals of Chinese had been taken into this case-control studies, which had been ...

journal_title：Molecular biology reports

authors： Zhang J,Yang B,Ying B,Li D,Shi Y,Song X,Cai B,Huang Z,Wu Y,Wang L

更新日期：2011-03-01 00:00:00

abstract：:The potential benefiting effects of probiotic Dahi on age-inflicted accumulation of oxidation products, antioxidant enzymes and expression of biomarkers of ageing were evaluated in mice. Probiotic Dahi were prepared by co-culturing in buffalo milk (3% fat) Dahi bacteria (Lactococcus lactis ssp. cremoris NCDC-86 and La...

journal_title：Molecular biology reports

authors： Kaushal D,Kansal VK

更新日期：2012-02-01 00:00:00

abstract：:Glutamate represents the main excitatory neurotransmitter in the mammalian brain; however, its excessive elevation in the extracellular space is cytotoxic and can result in neuronal death. The ischemia initiated brain damage reflects changes in glutamate concentration in peripheral blood. This paper investigated the r...

journal_title：Molecular biology reports

authors： Jachova J,Gottlieb M,Nemethova M,Bona M,Bonova P

更新日期：2020-07-01 00:00:00

abstract：:A chromosomal fragment containing purA, the nearest marker from the replication origin of the Bacillus subtilis chromosome, was highly purified as a complex containing at least proteins and being solubilized easily during cell lysis. The complex had a markedly higher sedimentation rate (70-120S) than the bulk of the s...

journal_title：Molecular biology reports

authors： Yamaguchi K,Yoshikawa H

更新日期：1976-07-01 00:00:00

abstract：:It has been demonstrated that ACSL3 and ACSL5 play important roles in fat metabolism. To investigate the primary functions of ACSL3 and ACSL5 and to evaluate their expression levels during goose fatty liver development, we cloned the ACSL3 and ACSL5 coding domain sequences (CDSs) of geese using RT-PCR and analyzed the...

journal_title：Molecular biology reports

authors： He H,Liu HH,Wang JW,Lv J,Li L,Pan ZX

更新日期：2014-01-01 00:00:00

abstract：:Evidence indicates that both S-adenosylmethionine (SAMe) metabolism and intramuscular fat are associated with insulin resistance and type II diabetes. However, it is still unknown whether SAMe have effects on intramuscular adipogenesis. The present study investigated the roles of SAMe in the adipogenic differentiation...

journal_title：Molecular biology reports

authors： Yue T,Fang Q,Yin J,Li D,Li W

更新日期：2010-10-01 00:00:00

abstract：:Analysis of in vivo phosphorylation of mouse liver ribosomal proteins was performed by two-dimensional polyacrylamide gel electrophoresis following 32P-injection. Our method is special and differs from other eukaryotic systems reported in that all proteins separated on the first dimension gel are completely solubilize...

journal_title：Molecular biology reports

authors： Hoffman WL,Ilan J

更新日期：1975-10-01 00:00:00

abstract：:Fusarium head blight (FHB), predominantly caused by Fusarium graminearum, is a destructive disease that poses a serious threat to wheat (Triticum aestivum L.) production around the world. A suppression subtractive hybridization (SSH) cDNA library was constructed from F. graminearum infected spikes of a resistant Belgi...

journal_title：Molecular biology reports

authors： Muhovski Y,Batoko H,Jacquemin JM

更新日期：2012-10-01 00:00:00

abstract：:Genes for individual domains such as CH, lim, ankyrin, PH and RhoGAP, IQ motif, Ig_FLMN, spectrin, and EF hand probably existed in early evolution before there were plants, fungi or animals so that when we examine multidomain proteins in Arabidopsis, Saccharomyces, Dictyostelium or Homo Sapiens we encounter various co...

journal_title：Molecular biology reports

authors： Friedberg F

更新日期：2011-01-01 00:00:00

abstract：:A full-length cDNA encoding wheat peroxisomal ascorbate peroxidase (pAPX) was cloned by Suppression Subtractive Hybridization (SSH) and in silico approach. The cDNA was 1027 bp in length and contained a complete ORF of 876 bp, which encodes a protein of 292 amino acid residues. Its deduced amino acids sequence had 84%...

journal_title：Molecular biology reports

authors： Chen Y,Wang H,Wang X,Cao A,Chen P

更新日期：2006-09-01 00:00:00

abstract：:The increasing worldwide incidence of mycobacteriosis and the need to achieve improved clinical management makes nontuberculous mycobacteria (NTM) genotyping a useful tool. However, because of technical difficulties, medium size microbiology laboratories do not attempt to compare the genetic patterns that each of thei...

journal_title：Molecular biology reports

authors： Blanco-Conde S,González-Cortés C,López-Medrano R,Palacios-Gutiérrez JJ,Diez-Tascón C,Nebreda-Mayoral T,Sierra-García MJ,Rivero-Lezcano OM

更新日期：2020-05-01 00:00:00

abstract：:Maize (Zea mays L.) is an important model plant with an important role in agriculture and national economies all over the world. The optimum growth temperature of maize is between 25 and 28 °C. At temperatures below 12 °C, maize is vulnerable to damage by chilling stress. MYB transcription factors play important roles...

journal_title：Molecular biology reports

authors： Li M,Lin L,Zhang Y,Sui N

更新日期：2019-08-01 00:00:00

abstract：:Repeated implantation failure (RIF) is one the most common causes which showed during IVF (In vitro fertilization) procedure. We aim to evaluate the possibility role of nucleotide changes in rs1042522 (R72P; G/C) and rs17878362 (Ins16bp; N/D) of P53 gene in patients with RIF. In a case-control survey, we have consider...

journal_title：Molecular biology reports

authors： Mohammadzadeh M,Ghorbian S,Nouri M

更新日期：2019-06-01 00:00:00

abstract：:Seed development is a complex process controlled by temporal and spatial expression of many transcription factors (TF) inside the developing seed. In the present study, transcript profiles of all the 30 members of rice DofTFs from flowering to seed development stages were analyzed. It was found that 16 Dof genes besid...

journal_title：Molecular biology reports

authors： Gaur VS,Singh US,Kumar A

更新日期：2011-04-01 00:00:00

abstract：:The purpose of this study was to identify genomic regions, quantitative trait loci (QTL), affecting carcass traits on chromosome 1 in an F2 population of Japanese quail. For this purpose, two white and wild strains of Japanese quail (16 birds) were crossed reciprocally and F1 generation (34 birds) was created. The F2 ...

journal_title：Molecular biology reports

authors： Moradian H,Esmailizadeh AK,Sohrabi SS,Nasirifar E,Askari N,Mohammadabadi MR,Baghizadeh A

更新日期：2014-07-01 00:00:00