microRNA-33-3p involved in selenium deficiency-induced apoptosis via targeting ADAM10 in the chicken kidney.

abstract：:We investigated the actions of human placental lactogen (HPL) and human growth hormone (HGH) on [3H]thymidine incorporation and the release of immunoassayable somatomedin-C (SM-C) by isolated myoblasts, dermal fibroblasts, and costal cartilage explants taken from human fetuses at 11-21 weeks of gestation. The incorpor...

journal_title：Journal of cellular physiology

authors： Hill DJ,Crace CJ,Milner RD

更新日期：1985-11-01 00:00:00

abstract：:Connective Tissue Growth Factor (CCN2/CTGF) and Nephroblastoma Overexpressed (CCN3/NOV) execute key functions within the hematopoietic compartment. Both are abundant in the bone marrow stroma, which is a niche for hematopoiesis and supports marrow function. Roles for 1,25-dihydroxyvitamin D3 (calcitriol) and all-trans...

journal_title：Journal of cellular physiology

authors： Piszczatowski RT,Rafferty BJ,Rozado A,Parziale JV,Lents NH

更新日期：2015-11-01 00:00:00

abstract：:Besides the liver, it has been difficult to identify which organ(s) and/or cellular component(s) contribute significantly to the production of human FVIII:c (FVIII). Thus far, only endothelial cells have been shown to constitute a robust extrahepatic source of FVIII, possibly explaining both the diverse presence of FV...

journal_title：Journal of cellular physiology

authors： Sanada C,Kuo CJ,Colletti EJ,Soland M,Mokhtari S,Knovich MA,Owen J,Zanjani ED,Porada CD,Almeida-Porada G

更新日期：2013-05-01 00:00:00

abstract：:Increasing evidence supports the idea that the finite proliferative life span of normal fibroblasts is a differentiation-like phenomenon. If this were correct, an ordered sequence of differential gene expression should be associated with the in vitro progression of cells from low passage to high passage (senescence). ...

journal_title：Journal of cellular physiology

authors： Choi AM,Olsen DR,Cook KG,Deamond SF,Uitto J,Bruce SA

更新日期：1992-04-01 00:00:00

abstract：:The non-POU-domain-containing octamer binding protein (NONO; also known as p54nrb) has various nuclear functions ranging from transcription, RNA splicing, DNA synthesis and repair. Although tyrosine phosphorylation has been proposed to account for the multi-functional properties of p54nrb, direct evidence on p54nrb as...

journal_title：Journal of cellular physiology

authors： Lee AR,Hung W,Xie N,Liu L,He L,Dong X

更新日期：2017-04-01 00:00:00

abstract：:Inhibition of the gap-filling, polymerizing step of excision repair by 1-beta-D-arabinofuranosylcytosine (ara-C) after irradiation with ultraviolet light in human diploid fibroblasts resulted in the formation of persistent DNA strand breaks in G1, G2, and plateau phase cells, but not in S phase cells. Addition of hydr...

journal_title：Journal of cellular physiology

authors： Cleaver JE

更新日期：1981-08-01 00:00:00

abstract：:Sevoflurane has been commonly utilized in nonobstetric surgeries in pregnant women, and its impacts on fetal brain are still not completely known. Ectopic NR4A2 expression has been reported to be related with familial Parkinson disease, and through dual luciferase we found that NR4A2 is a target gene of microRNA-183 (...

journal_title：Journal of cellular physiology

authors： Shao CZ,Xia KP

更新日期：2019-04-01 00:00:00

abstract：:The simultaneous exposure of WI-38 human fibroblasts (HF) to a heat shock (45 degrees C, 30 min) and an alkaline shift (> or = pH 8.0) in the incubation medium increased and extended the expression of heat shock proteins (hsps). Hsp70 was the most prominent inducible hsp synthesized during the recovery phase after the...

journal_title：Journal of cellular physiology

authors： Petronini PG,Alfieri R,Campanini C,Borghetti AF

更新日期：1995-03-01 00:00:00

abstract：:We determined the synthesis and secretion of glycosaminoglycans by three distinct preparations of mouse cultured thymic epithelial cells. These comprised primary cultures of thymic nurse cells (TNCs), which are normally located within the cortex of the thymic lobules, as well as two murine thymic epithelial cells, bea...

journal_title：Journal of cellular physiology

authors： Werneck CC,Cruz MS,Silva LC,Villa-Verde DM,Savino W,Mourão PA

更新日期：2000-10-01 00:00:00

abstract：:In novel coronavirus disease 2019 (COVID-19), the increased frequency and overactivation of T helper (Th) 17 cells and subsequent production of large amounts of proinflammatory cytokines result in hyperinflammation and disease progression. The current study aimed to investigate the therapeutic effects of nanocurcumin ...

journal_title：Journal of cellular physiology

authors： Tahmasebi S,El-Esawi MA,Mahmoud ZH,Timoshin A,Valizadeh H,Roshangar L,Varshoch M,Vaez A,Aslani S,Navashenaq JG,Aghebati-Maleki L,Ahmadi M

更新日期：2020-12-28 00:00:00

abstract：:Transient Receptor Potential Vanilloid type 1 channel (TRPV1) is an important endogenous transducer of noxious heat and chemical stimuli and is required during development of inflammatory hypersensitivity. The transcription factor Runx1 is known to play a relevant role in sensory neuron differentiation as it controls ...

journal_title：Journal of cellular physiology

authors： Ugarte GD,Diaz E,Biscaia M,Stehberg J,Montecino M,van Zundert B

更新日期：2013-04-01 00:00:00

abstract：:P-glycoproteins (Pgp) are comprised of a small family of plasma membrane proteins whose abundance in cultured cells is often associated with the multidrug resistance phenotype. Overexpression of Pgp has been observed in many types of human cancers, but the molecular basis for this overexpression has not been establish...

journal_title：Journal of cellular physiology

authors： Lee CH,Bradley G,Ling V

更新日期：1998-10-01 00:00:00

abstract：:Prkdc encodes for the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs) playing a key role in nonhomologous end joining pathway during DNA double-strand break repair and also influencing the homologous recombination (HR) repair system by phosphorylation of proteins involved in HR. In addition, Prkdc has...

journal_title：Journal of cellular physiology

authors： Soleimani F,Babaei E,H Feizi MA,Fathi F

更新日期：2020-04-01 00:00:00

abstract：:The S100 protein family comprises more than 20 members of small calcium binding proteins operating as Ca2 +-activated switches that interact and modulate the activity of a large number of targets. S100A1 and S100B, two members of this family, have been recently associated with the differentiation status of human artic...

journal_title：Journal of cellular physiology

authors： Diaz-Romero J,Nesic D

更新日期：2017-08-01 00:00:00

abstract：:Tobacco smoking is associated with many diseases. Addiction is of the most notorious tobacco-related syndrome and is mainly attributed to nicotine. In this study, we employed Caenorhabditis elegans as a biological model to systemically investigate the effect of chronic nicotine exposure on microRNA (miRNA) expression ...

journal_title：Journal of cellular physiology

authors： Taki FA,Pan X,Zhang B

更新日期：2014-01-01 00:00:00

abstract：:The progression of T-lymphoma cells (CCRF-CEM) growing in suspension has been monitored during long term (12-28 h) batch experiments using microcalorimetry. In parallel with the calorimetric measurements, changes in cell concentration, pH, p(O2) and concentrations of the main energy sources (glucose and glutamine) wer...

journal_title：Journal of cellular physiology

authors： Bäckman P,Kimura T,Schön A,Wadsö I

更新日期：1992-01-01 00:00:00

abstract：:We present evidence that extends our earlier preliminary report on the stimulatory effect of saline washes on confluent cells in culture (Lacey et al., '77). That work suggested that an inhibitory substance was being removed by the washes. The present work suggests that the inhibitor is in the 10,000-30,000 MW range, ...

journal_title：Journal of cellular physiology

authors： Strobel-Stevens JD,Lacey JC Jr

更新日期：1981-02-01 00:00:00

abstract：:Myocardin is a transcriptional co-activator of serum response factor (SRF) and can be degraded through ubiquitin-proteasome system. Our preliminary studies unexpectedly revealed that accumulation of myocardin in response to proteasome inhibition by MG132 or lactacystin resulted in decrease of transcriptional activity ...

journal_title：Journal of cellular physiology

authors： Yin H,Jiang Y,Li H,Li J,Gui Y,Zheng XL

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Cigarette smoke exposure, increasing Toll-like receptor 4 (TLR4) and reactive oxygen species (ROS), promotes inflammatory responses in airway epithelial cells. Chronic inflammation, microRNA (miRNA), and oxidative stress are associated with cancer development. AIMS:The present study was aimed to explore whe...

journal_title：Journal of cellular physiology

authors： Pace E,Di Vincenzo S,Di Salvo E,Genovese S,Dino P,Sangiorgi C,Ferraro M,Gangemi S

更新日期：2019-12-01 00:00:00

abstract：:Heparin and related glycosaminoglycans are potent inhibitors of both in vivo and in vitro smooth muscle cell (SMC) proliferation. We have found that epidermal growth factor (EGF) reverses the antiproliferative effects of heparin. Other known SMC mitogens, including platelet-derived growth factor (PDGF), insulin-like g...

journal_title：Journal of cellular physiology

authors： Reilly CF,Fritze LM,Rosenberg RD

更新日期：1987-05-01 00:00:00

abstract：:The aim of the present work was to examine the role of muscarinic acetylcholine receptors (mAChRs) on apoptosis in human skin fibroblast cells. Neonatal human skin fibroblast cultures were stimulated with pilocarpine in the presence or absence of specific antagonists. Pilocarpine stimulates apoptosis, total inositol p...

journal_title：Journal of cellular physiology

authors： Reina S,Sterin-Borda L,Passafaro D,Borda E

更新日期：2010-03-01 00:00:00

abstract：:Connective tissue growth factor (CTGF) is a secreted, extracellular matrix-associated signaling protein that regulates diverse cellular functions. In vivo, CTGF is expressed in many tissues with highest levels in the kidney and brain. The purpose of this study was twofold; first, to localize CTGF in normal bone in viv...

journal_title：Journal of cellular physiology

authors： Safadi FF,Xu J,Smock SL,Kanaan RA,Selim AH,Odgren PR,Marks SC Jr,Owen TA,Popoff SN

更新日期：2003-07-01 00:00:00

abstract：:Four cell lines, named nonparenchymal 11 (NP11), NP26, NP31, and NP32, were established from sinusoidal endothelial cells (SECs) of rat liver. They still retained expression of receptors for vascular endothelial growth factor (VEGF), Fit-1, and kinase domain-containing receptor (KDR). NP31 and NP32 turned out to be in...

journal_title：Journal of cellular physiology

authors： Maru Y,Yamaguchi S,Takahashi T,Ueno H,Shibuya M

更新日期：1998-08-01 00:00:00

abstract：:Human cell lines derived from a melanoma and a colon carcinoma, and cultures of human melanocytes and intestinal epithelial cells, as well as a mouse mesenchymal non-neoplastic cell line and a malignant subline of the same have been quantitatively studied in tissue culture for their sensitivity to thymidine. All three...

journal_title：Journal of cellular physiology

authors： Lee SS,Giovanella BC,Stehlin JS Jr

更新日期：1977-09-01 00:00:00

abstract：:The study was conducted on human leukemia (K 562) cells to characterize the mechanisms implicated in the regulation of the polyamine spermidine (Spd) transport process. The antagonists of calmodulin, trifluoperazine (TFP), W-7 (N-[6-aminohexyl]-5-chloro-1-naphthelenesulfonamide), or mellitin inhibited significantly po...

journal_title：Journal of cellular physiology

authors： Khan NA,Sezan A,Quemener V,Moulinoux JP

更新日期：1993-12-01 00:00:00

abstract：:The molecular mechanism by which thyroid hormones exert their effects on cell growth is still unknown. In this study, we used chick embryo hepatocytes at different stages of development as a model to investigate the effect of the two thyroid hormones, T3 and T4, and of their metabolite T2, on the control of cell proli...

journal_title：Journal of cellular physiology

authors： Alisi A,Spagnuolo S,Napoletano S,Spaziani A,Leoni S

更新日期：2004-11-01 00:00:00

abstract：:Fibroblast growth factor (FGF)-21 is a novel regulator of insulin-independent glucose transport in 3T3-L1 adipocytes and has glucose and triglyceride lowering effects in rodent models of diabetes. The precise mechanisms whereby FGF-21 regulates metabolism remain to be determined. Here we describe the early signaling e...

journal_title：Journal of cellular physiology

authors： Moyers JS,Shiyanova TL,Mehrbod F,Dunbar JD,Noblitt TW,Otto KA,Reifel-Miller A,Kharitonenkov A

更新日期：2007-01-01 00:00:00

abstract：:Cyclosporine A (CyA) is a powerful nonsteroidal immunosuppressive agent used to prevent graft rejection of organ and bone marrow transplants. A major side effect observed can be attributed to the fibroblast and its functions: proliferation of fibroblasts and formation of fibrotic tissue in the gingiva (fibrous hyperpl...

journal_title：Journal of cellular physiology

authors： Willershausen-Zönnchen B,Lemmen C,Schumacher U

更新日期：1992-08-01 00:00:00

abstract：:Chronic hyperglycemia and activation of receptor for advanced glycation end products (RAGE) are known risk factors for microvascular disease development in diabetic retinopathy. Thioredoxin-interacting protein (TXNIP), an endogenous inhibitor of antioxidant thioredoxin (TRX), plays a causative role in diabetes and its...

journal_title：Journal of cellular physiology

authors： Perrone L,Devi TS,Hosoya K,Terasaki T,Singh LP

更新日期：2009-10-01 00:00:00

abstract：:Di- and tripeptides and peptide mimetics such as beta-lactam antibiotics are efficiently reabsorbed from the tubular lumen by a high-affinity peptide transporter. We have recently identified and characterized this H+-coupled high-affinity peptide transport system in the porcine proximal tubular cell line LLC-PK1. Here...

journal_title：Journal of cellular physiology

authors： Wenzel U,Diehl D,Herget M,Kuntz S,Daniel H

更新日期：1999-03-01 00:00:00