Health-related quality of life, clinical outcomes, and subjective experiences of parent donors of pediatric liver transplant recipients.

Abstract:

PURPOSE:The understanding of the HRQOL issues for parent donors of children who underwent LDLT is lacking. We evaluated the HRQOL of donor and non-donor parents, described their subjective experiences and identified factors associated with lower HRQOL post-donation. METHODS:This is a cross-sectional study of parent donors whose children underwent LDLT, using SF-36v2 Health Survey to measure HRQOL, and a self-developed questionnaire to evaluate their subjective experiences. RESULTS:Of 32 pairs of donor and non-donor parents, 27 donor and 19 non-donor parents responded. The data of respondents were analyzed. Both donor and non-donor parents' SF-36v2 norm-based scores were average or above average as compared to the Singapore population. Donors who made lifestyle changes post-donation (adopting a healthy balanced diet, regular physical activity, quitting smoking, and moderate alcohol intake) were associated with lower GH (P = 0.009) and PF (P = 0.002) scores. Donors who took more than 3 months for full recovery had lower RP (P = 0.022) and BP scores (P = 0.038). On multivariate analysis, recipient complication of Clavien grade 3 or 4 was associated with increased RP score by 8.71 points (95% CI: 1.74-15.68), after adjusting for time taken for full recovery. Majority (88.8%) had self-reported recovery time under 6 months and returned to work within 3 months (74.0%). CONCLUSIONS:Donors with factors potentially associated with lower HRQOL may need more support to ensure better HRQOL outcomes post-donation.

journal_name

Pediatr Transplant

authors

Yuen WY,Tan A,Karthik SV,Quak SH,Kow AW,Aw MM

doi

10.1111/petr.13337

subject

Has Abstract

pub_date

2019-03-01 00:00:00

pages

e13337

issue

2

eissn

1397-3142

issn

1399-3046

journal_volume

23

pub_type

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