Genetic variation and hematopoietic stem cell transplantation: expansion of the paradigm.

abstract：:Abdominal wall closure after pediatric liver transplantation (pLT) in infants may be hampered by graft-to-recipient size discrepancy. Herein, we describe the use of a porcine dermal collagen acellular graft (PDCG) as a biological mesh (BM) for abdominal wall closure in pLT recipients. Patients <2 years of age, who und...

journal_title：Pediatric transplantation

authors： Gül-Klein S,Dziodzio T,Martin F,Kästner A,Witzel C,Globke B,Jara M,Ritschl PV,Henning S,Gratopp A,Bufler P,Schöning W,Schmelzle M,Pratschke J,Öllinger R

更新日期：2020-05-01 00:00:00

abstract：:Omenn's syndrome is a rare inherited variant of SCID. It is inevitably fatal, unless treated by bone marrow or stem cell transplantation. However, treatment-related complications and graft rejection are major obstacles to the success of transplantation. In this report, we describe an eight-month-old baby with Omenn's ...

journal_title：Pediatric transplantation

authors： Wahadneh A,Bin-Dahman H,Habahbeh Z,Abu-Shukear M,Ajarmeh M,Zyood R,Khaled A

更新日期：2012-03-01 00:00:00

abstract：:EPVO is a common cause of prehepatic portal hypertension in pediatric patients and sometimes results in cavernous transformation of the PV. We herein present the cases of two patients who underwent LDLT for EPVO with post-Kasai biliary atresia. PV reconstruction was performed with a porto-left gastric vein anastomosis...

journal_title：Pediatric transplantation

authors： Kitajima T,Sakamoto S,Uchida H,Hamano I,Kobayashi M,Kanazawa H,Fukuda A,Kasahara M

更新日期：2013-05-01 00:00:00

abstract：:Even if kidney graft survival has improved during the last decades, sensitized pediatric patients are an emerging problem. We describe a 17-yr-old male who lost his first graft due to chronic rejection becoming hyperimmunized (CDC PRA 99.61%). A desensitization protocol based on high-dose IVIG, PP, and two Mabthera(®)...

journal_title：Pediatric transplantation

authors： Ghirardo G,Benetti E,Poli F,Vidal E,Della Vella M,Cozzi E,Murer L

更新日期：2014-02-01 00:00:00

abstract：:Tacrolimus-based immunosuppression in pediatric liver transplant recipients is known to be associated with EGID. Our goal was to determine the incidence, risk factors, and characteristics of EGID in our pediatric liver transplantation program. This study was a retrospective analysis of 38 pediatric liver transplant re...

journal_title：Pediatric transplantation

authors： Lee JH,Park HY,Choe YH,Lee SK,Lee SI

更新日期：2007-08-01 00:00:00

abstract：:Respiratory syncytial virus (RSV) is an important cause of lower respiratory tract infection in infants and young children. In immunocompromised children, RSV infection poses a serious health threat with significantly increased and prolonged virus shedding and the development of severe respiratory disease. We report t...

journal_title：Pediatric transplantation

authors： Blanchard SS,Gerrek M,Siegel C,Czinn SJ

更新日期：2006-11-01 00:00:00

abstract：:eHAT is one of the most dreaded post-LT complication. Treatment approaches include retransplantation, revascularization, or observation. Systemic thrombolytic therapy is used in pediatric patients with thromboembolic events. However, there is no previous study reporting on the use of systemic r-tPA to treat eHAT. The ...

journal_title：Pediatric transplantation

authors： Feier FH,Melere MU,Trein CS,da Silva CS,Lucchese A,Horbe A,Tonet F,Ricachinevsky C,Ferreira CT,Chedid MF,Kalil AN

更新日期：2020-10-27 00:00:00

abstract：:aHUS is caused by the over-activation and dysregulation of the alternative complement pathway. Data regarding outcomes of pediatric aHUS patients after kidney transplantation are still very scarce. Accordingly, the aim of this study was to describe the clinical findings and outcomes of pediatric aHUS patients after re...

journal_title：Pediatric transplantation

authors： Özçakar ZB,Ozaltin F,Gülhan B,Çomak E,Parmaksız G,Baskın E,Topaloğlu R,Kasap Demir B,Canpolat N,Yuruk Yildirim Z,Demircioğlu Kılıç B,Yüksel S,Söylemezoğlu O

更新日期：2020-11-20 00:00:00

abstract：:The potentially curative role of allogeneic hematopoietic cell transplantation (HCT) in neoplastic and non-neoplastic diseases is offset by the substantial risks of morbidity and mortality from complications of the intensive myeloablative and immunosuppressive preparative regimen. These regimen-related toxicities have...

journal_title：Pediatric transplantation

authors： Schwartz JE,Yeager AM

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Heart transplant waitlist mortality remains high in infants <1 year of age and among those with CHD. Currently, the median accepted donor-to-recipient weight percentage is approximately 130% of the recipient's weight. We hypothesized that patients with CHD may accept a larger organ using novel 3D-derived ima...

journal_title：Pediatric transplantation

authors： Shugh SB,Szugye NA,Zafar F,Riggs KW,Villa C,Lorts A,Morales DLS,Moore RA

更新日期：2020-02-01 00:00:00

abstract：:LDLT is a well-established treatment for most terminal liver diseases in children. Survival rates have improved, yet few studies have considered HRQoL or sleep problems in LDLT recipients. In this cross-sectional study, we enrolled 51 children who had undergone LDLT in Renji Hospital. PedsQL(™) 4.0 Generic Core Scales...

journal_title：Pediatric transplantation

authors： He K,Shen C,Chen X,Han L,Xi Z,Zhou T,Zhang J,Xia Q

更新日期：2015-08-01 00:00:00

abstract：:Diaphragmatic hernia after OLT is a rare surgical complication. We here report successful diagnosis and treatment of two cases with right-sided diaphragmatic hernia developed after OLT both utilizing left-sided allografts. Combination of factors related to the surgical techniques and patient characteristics might expl...

journal_title：Pediatric transplantation

authors： Kazimi M,Ibis C,Alper I,Ulas M,Baran M,Arikan C,Aydogdu S,Ulukaya S,Zeytunlu M,Kilic M

更新日期：2010-08-01 00:00:00

abstract：:DIDS is a unique form of combined immune deficiency characterized by an unusual susceptibility to cutaneous viral infections, severe allergies with eosinophilia and elevated immunoglobulin E titers, autoimmunity, and cancer. HSCT is considered the standard of care for this deadly disease. We have retrospectively analy...

journal_title：Pediatric transplantation

authors： Uygun DFK,Uygun V,Reisli İ,Keleş S,Özen A,Yılmaz M,Sayar EH,Daloğlu H,Öztürkmen SI,Çakı S,Karasu GT,Yeşilipek A

更新日期：2017-11-01 00:00:00

abstract：:Non-adherence to immunosuppressant medications is an important risk factor for graft dysfunction. To evaluate the effectiveness of adherence-enhancing interventions, we reviewed adherence intervention studies in solid organ transplant recipients (all ages). Using the following databases: PsycINFO, PubMed, Scopus, and ...

journal_title：Pediatric transplantation

authors： Duncan S,Annunziato RA,Dunphy C,LaPointe Rudow D,Shneider BL,Shemesh E

更新日期：2018-02-01 00:00:00

abstract：:Adults, older children, and adolescent patients with a BMI categorized as overweight or obese have decreased survival after HTx. Anthropometric correlates of survival after HTx in infants have not been well defined. In a retrospective analysis of the UNOS registry, patients age 0-24 months were classified according to...

journal_title：Pediatric transplantation

authors： McKee C,Tumin D,Hayes D Jr,Tobias JD

更新日期：2016-12-01 00:00:00

abstract：:It is the practice of many pediatric renal transplant programs to 'convert' children taking cyclosporin A (CsA) to tacrolimus, although the indications for, outcome, and complications of this practice remain obscure. To better understand these aspects of tacrolimus 'conversion', a fax survey was sent to 119 North Amer...

journal_title：Pediatric transplantation

authors： Flynn JT,Bunchman TE,Sherbotie JR

更新日期：2001-12-01 00:00:00

abstract：:Vaccination of pediatric liver transplant candidates and recipients represents an opportunity to decrease infectious complications following transplant. Although vaccine recommendations exist, studies have shown that many transplant candidates and recipients are under-immunized. The goals of this study were to assess ...

journal_title：Pediatric transplantation

authors： Feldman AG,Kempe A,Beaty BL,Sundaram SS,Studies of Pediatric Liver Transplantation (SPLIT) Research Group.

更新日期：2016-12-01 00:00:00

abstract：:The waiting period for an organ transplant has been described as a time of tremendous uncertainty and vulnerability, posing unique challenges and stressors for pediatric transplant candidates and their families. It has been identified as the most stressful stage of the transplant journey, yet little attention has been...

journal_title：Pediatric transplantation

authors： Anthony SJ,Annunziato RA,Fairey E,Kelly VL,So S,Wray J

更新日期：2014-08-01 00:00:00

abstract：:CKD is a major co-morbidity in pediatric lung transplant recipients. We report the prevalence of renal impairment post-lung transplant at a single center, using a modified, age-adjusted eGFR for the best approximation of true GFR, and investigated associations and possible predictors of decline in renal function post-...

journal_title：Pediatric transplantation

authors： Benden C,Kansra S,Ridout DA,Shaw NL,Aurora P,Elliott MJ,Marks SD

更新日期：2009-02-01 00:00:00

abstract：:This review focuses on active clinical research in pediatric liver transplantation with special emphasis on areas that could benefit from studies utilizing the SPLIT infrastructure and data repository. Ideas were solicited by members of the SPLIT Research Committee and sections were drafted by members of the committee...

journal_title：Pediatric transplantation

authors： Alonso EM,Ng VL,Anand R,Anderson CD,Ekong UD,Fredericks EM,Furuya KN,Gupta NA,Lerret SM,Sundaram S,Tiao G,Studies of Pediatric Liver Transplantation (SPLIT) Research Group.

更新日期：2013-08-01 00:00:00

abstract：:In areas of the world where human herpesvirus 8 (HHV-8) is endemic, Kaposi sarcoma (KS) is a common SOT-associated cancer. In the United States, where the virus is not prevalent, PTKS is rare, and there is little literature on pediatric PTKS. We present a North American female who underwent deceased donor, left latera...

journal_title：Pediatric transplantation

authors： Ocwieja KE,Vargas SO,Elisofon SA,Shulman DS,Lee CK,Fawaz R,Collins N,Vakili K,Sharma TS

更新日期：2019-05-01 00:00:00

abstract：:De novo PTAID may develop in pediatric solid organ transplant recipients, have a diverse spectrum, and are occasionally treatment resistant. Previous reports showed resolution of immune cytopenias in solid organ transplant recipients following replacement of the calcineurin inhibitor tacrolimus with the mTOR inhibitor...

journal_title：Pediatric transplantation

authors： Kehar M,Grunebaum E,Jimenez-Rivera C,Mozer-Glassberg Y,Jamal A,Ng VL,Avitzur Y

更新日期：2020-09-01 00:00:00

abstract：:The availability of new and more effective anti-rejection therapy has succeeded in reducing the incidence of acute cellular rejection in first months post-renal transplant. This in turn has escalated the order of significance of recurrence of primary disease in the renal allograft as a cause for patient morbidity and ...

journal_title：Pediatric transplantation

authors： Seikaly MG

更新日期：2004-04-01 00:00:00

abstract：:This study evaluated changes in growth parameters after pediatric heart transplantation and identified factors associated with the changes after pediatric heart transplantation (OHT). We retrospectively evaluated the somatic growth of 46 children <11 yr of age who underwent OHT for changes in weight, height, and BMI. ...

journal_title：Pediatric transplantation

authors： Peterson RE,Perens GS,Alejos JC,Wetzel GT,Chang RK

更新日期：2008-06-01 00:00:00

abstract：:Cystic fibrosis (CF) is an inherited disease with a defect in epithelial chloride transport that results in a multisystem disease. Although pulmonary disease remains the primary cause of morbidity and mortality, focal biliary cirrhosis and portal hypertension may develop in up to 8% of these patients. Liver transplant...

journal_title：Pediatric transplantation

authors： Henn C,Kapellen T,Prenzel F,Siekmeyer M,Hau HM,Kiess W,Bartels M

更新日期：2014-02-01 00:00:00

abstract：:There is a limited supply of organs for all those who need them for survival. Thus, careful decisions must be made about who is listed for transplant. Studies show that manifesting genetic disease can impact listing eligibility. What has not yet been studied is the impact genetic risks for future disease have on a pat...

journal_title：Pediatric transplantation

authors： Graf M,Char D,Hanson-Kahn A,Magnus D

更新日期：2019-06-01 00:00:00

abstract：:Autoimmune and allergic diseases cause morbidity and diminished quality of life in pediatric organ transplant recipients. We hypothesize that younger age at transplantation and immunosuppression regimen play a role in the development of immune-mediated disease following heart transplant. A single institution retrospec...

journal_title：Pediatric transplantation

authors： Mouledoux JH,Albers EL,Lu Z,Saville BR,Moore DJ,Dodd DA

更新日期：2014-03-01 00:00:00

abstract：:Success after solid organ transplantation is dependent on the proper balance of immunosuppression to prevent rejection of the allograft while limiting the risk of developing infections and malignancy. We present a 9-year-old girl, remote from transplant, who presented with airway plaque after a change in immunosuppres...

journal_title：Pediatric transplantation

authors： Ryan TD,Absalon MJ,de Alarcon A,Gupta A,Peters AL,Lorts A,Danziger-Isakov LA,Chin C

更新日期：2017-11-01 00:00:00

abstract：:Rural status of patients may impact health before and after pediatric LT. We used UI codes published by the USDA to stratify patients as urban or rural depending county residence. A total of 388 patients who had LT and who met criteria were included. Rejection, PTLD, and survival were used as primary outcome measures ...

journal_title：Pediatric transplantation

authors： Park KT,Nanda P,Bensen R,Strichartz D,Esquivel C,Cox K

更新日期：2011-05-01 00:00:00

abstract：:Incomplete resolution of abnormalities of mineral metabolism associated with CRF results in the relatively high prevalence of ROD in pediatric kidney recipients. This non-randomized, cross-sectional, and analytic-descriptive study on bone density, vitamin D, and mineral metabolism was performed in 57 children and adol...

journal_title：Pediatric transplantation

authors： Derakhshan A,Behbahan AG,Lotfi M,Omrani GH,Fallahzadeh MH,Basiratnia M,Al-Hashemi GH

更新日期：2011-06-01 00:00:00