The successful use of alemtuzumab for treatment of steroid-refractory acute graft-versus-host disease in pediatric patients.

abstract：:Medical cannabis is now legal in over half of the United States. As more patients adopt this unconventional therapy, it is inevitable that potential transplant recipients will disclose their cannabis use during transplant evaluation. Transplant teams are tasked with the decision to utilize a pressure resource, often w...

journal_title：Pediatric transplantation

authors： Ryan JE,Noeder M,Burke C,Stubblefield SC,Sulieman S,Miller EG

更新日期：2019-08-01 00:00:00

abstract：:The aim of this study is to correlate the US, laboratory, and cholangiography findings in pediatric liver transplant patients with biliary complications, trying to identify reliable decision-making tools for the management of these complications. Retrospective review was carried out of US results in 39 consecutive pat...

journal_title：Pediatric transplantation

authors： Teplisky D,Urueña Tincani E,Halac E,Garriga M,Cervio G,Imventarza O,Sierre S

更新日期：2015-03-01 00:00:00

abstract：:An increasing number of individuals with end-stage renal disease have become sensitized to human leukocyte antigens (HLA). Sensitization can have a profound impact on the likelihood of obtaining a requisite negative crossmatch (-XM) with a potential donor. Technologic breakthroughs in our ability to diagnose antibody-...

journal_title：Pediatric transplantation

authors： Montgomery RA,Zachary AA

更新日期：2004-12-01 00:00:00

abstract：:Dyslipidemia contributes to cardiovascular morbidity and mortality in pediatric transplant recipients. Data on prevalence and risk factors in pediatric cohorts are, however, scarce. We therefore determined the prevalence of dyslipidemia in 386 pediatric renal transplant recipients enrolled in the CERTAIN registry. Dat...

journal_title：Pediatric transplantation

authors： Habbig S,Volland R,Krupka K,Querfeld U,Dello Strologo L,Noyan A,Yalcinkaya F,Topaloglu R,Webb NJ,Kemper MJ,Pape L,Bald M,Kranz B,Taylan C,Höcker B,Tönshoff B,Weber LT

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:No previous paediatric study has evaluated the frequency of diagnostic disagreement between clinical standard histopathological assessment (CSHA) and retrospective, independent, histopathological assessment (RIHA) of gastrointestinal Graft-Versus-Host Disease (GI-GVHD) METHODS: In a retrospective cohort stud...

journal_title：Pediatric transplantation

authors： Mårtensson T,Szakos A,Mellgren K,Toporski J,Arvidson J,Mattsson J,Gustafsson B,Casswall TH

更新日期：2020-12-01 00:00:00

abstract：PURPOSE:The understanding of the HRQOL issues for parent donors of children who underwent LDLT is lacking. We evaluated the HRQOL of donor and non-donor parents, described their subjective experiences and identified factors associated with lower HRQOL post-donation. METHODS:This is a cross-sectional study of parent do...

journal_title：Pediatric transplantation

authors： Yuen WY,Tan A,Karthik SV,Quak SH,Kow AW,Aw MM

更新日期：2019-03-01 00:00:00

abstract：:ADV is frequently seen in our pediatric SOT population. It presents in a variety of clinical presentation and can cause severe disease. In this population, there are very few studies to determine the safety of CDV as a potential therapeutic agent. We present the findings of our retrospective study evaluating the effic...

journal_title：Pediatric transplantation

authors： Guerra Sanchez CH,Lorica CD,Arheart KL,Perez MM,Tekin A,Gonzalez IA

更新日期：2018-06-03 00:00:00

abstract：:Studies are increasingly recognizing health-related quality of life (HRQOL) as a key pediatric outcome in both clinical and research settings and an essential health outcome measure to assess the effectiveness of medical treatment. However, it has not yet been studied among the healthy siblings of kidney transplant re...

journal_title：Pediatric transplantation

authors： Velasco J,Ferraris JR,Eymann A,Ghezzi LFR,Coccia PA,Ferraris V

更新日期：2020-08-01 00:00:00

abstract：:Mortality is the highest of any solid organ in pediatric patients awaiting heart transplantation. Strategies to increase the donor pool are needed if survival to transplant is to improve. There can be reluctance to accept pediatric hearts for transplantation if the donor has received cardiopulmonary resuscitation (CPR...

journal_title：Pediatric transplantation

authors： L'Ecuyer T,Sloan K,Tang L

更新日期：2011-11-01 00:00:00

abstract：:UCBT recipients with TM are at high risk of EF related to low number of stem cells and prior alloimmunization after multiple blood transfusions. Here, we evaluated the safety and efficacy of double-unit UCBT using TT-containing conditioning regimens in TM. Retrospective analysis of children who underwent double-unit U...

journal_title：Pediatric transplantation

authors： Feng J,Lee V,Leung AWK,Lam GKS,Chow TTW,Cheng FWT,Yan CLS,Lee CK,Yuen PMP,Li CK

更新日期：2020-11-02 00:00:00

abstract：:Patients with defects in the ATP6AP1 gene have rarely been described. ATP6AP1-related disorders are a subtype of CDG, which result in enzyme deficiencies affecting multiple organ systems ranging from mild to life-threatening. Of the 13 patients described, all had hepatopathy, but this is the first case to be successfu...

journal_title：Pediatric transplantation

authors： Gumm AJ,Basel DG,Thakrar P,Suchi M,Telega G

更新日期：2020-12-01 00:00:00

abstract：:Anelloviruses are DNA viruses ubiquitously present in human blood. Due to their elevated levels in immunosuppressed patients, anellovirus levels have been proposed as a marker of immune status. We hypothesized that low anellovirus levels, reflecting relative immunocompetence, would be associated with adverse outcomes ...

journal_title：Pediatric transplantation

authors： Blatter JA,Sweet SC,Conrad C,Danziger-Isakov LA,Faro A,Goldfarb SB,Hayes D Jr,Melicoff E,Schecter M,Storch G,Visner GA,Williams NM,Wang D

更新日期：2018-02-01 00:00:00

abstract：:Pneumatosis intestinalis is an uncommon finding beyond the neonatal period, but it has been reported in immunocompromized pediatric patients. The association of pneumatosis intestinalis in children following renal transplantation has to the best of our knowledge been only reported once in children. We describe a 4-yea...

journal_title：Pediatric transplantation

authors： Chelimsky G,Blanchard S,Sivit C,Davis I,Czinn S

更新日期：2003-06-01 00:00:00

abstract：:Bacillus cereus is a spore-forming, gram-positive bacterium that causes food poisoning presenting with either emesis or diarrhea. Diarrhea is caused by proteinaceous enterotoxin complexes, mainly hemolysin BL, non-hemolytic enterotoxin (NHE), and cytotoxin K. In contrast, emesis is caused by the ingestion of the depsi...

journal_title：Pediatric transplantation

authors： Tschiedel E,Rath PM,Steinmann J,Becker H,Dietrich R,Paul A,Felderhoff-Müser U,Dohna-Schwake C

更新日期：2015-02-01 00:00:00

abstract：:A major risk faced by bone-marrow and solid organ transplant patients is the development of post-transplant lymphoproliferative disease or post-transplant lymphoma (PTLD). In pediatric transplantation, PTLD onset is often associated with a rapid rise in Epstein-Barr virus (EBV) load in peripheral blood mononuclear cel...

journal_title：Pediatric transplantation

authors： Orentas RJ,Schauer DW Jr,Ellis FW,Walczak J,Casper JT,Margolis DA

更新日期：2003-08-01 00:00:00

abstract：:Rabbit antithymocyte globulin (ATG-F) is an extensively used induction agent. To our knowledge, no study to date has assessed reduced ATG-F dosage in children undergoing renal transplantation. This was a retrospective analysis of pediatric renal recipients in the Department of Kidney Transplantation, The First Affilia...

journal_title：Pediatric transplantation

authors： Shang W,Feng G,Gao S,Wang Z,Pang X,Li J,Liu L,Feng Y,Xie H,Zhang S,Qiao B

更新日期：2014-05-01 00:00:00

abstract：:The majority of transplant centers around the world face an ethical debate whether to retransplant a young non-adherent patient. Non-adherence to lifelong immunosuppressants presents a significant risk for graft loss, yet rates remain consistently high. Despite a number of these patients presenting for retransplantati...

journal_title：Pediatric transplantation

authors： Dobbels F,Hames A,Aujoulat I,Heaton N,Samyn M

更新日期：2012-02-01 00:00:00

abstract：:Chronic rejection is the leading cause of graft loss following pediatric kidney transplantation. Our group and others have demonstrated an association between the development of Abs to self-antigens and chronic rejection following adult lung and heart transplantation. The goal of this study was to determine whether Ab...

journal_title：Pediatric transplantation

authors： Hesemann LE,Subramanian V,Mohanakumar T,Dharnidharka VR

更新日期：2015-08-01 00:00:00

abstract：:INFVA is an important cause of pulmonary infections in patients receiving BMT, and is associated with considerable morbidity and mortality for a readily preventable and treatable infection. Few studies have addressed the impact of the new neuraminidase inhibitors in the prognosis of influenza after BMT. The aim of thi...

journal_title：Pediatric transplantation

authors： Mellouli F,Ouederni M,Dhouib N,Hajkacem MA,Slim A,Bejaoui M

更新日期：2010-03-01 00:00:00

abstract：:Rejection remains a major threat in pediatric renal transplantation (Tx), causing graft failure and increased exposure to drugs. The new chimeric antibody, basiliximab, directed against the alpha-chain of the interleukin-2 receptor (IL-2R), has been shown to be effective in preventing rejection episodes in adult renal...

journal_title：Pediatric transplantation

authors： Vester U,Kranz B,Testa G,Malagò M,Beelen D,Broelsch CE,Hoyer PF

更新日期：2001-08-01 00:00:00

abstract：:The adjusted relative risk (aRR) for development of post-transplant lymphoproliferative disorder (PTLD) is higher in kidney transplant recipients receiving monoclonal antibody induction therapy, but the aRR between the different available polyclonal agents has not been investigated in detail. We analyzed data from the...

journal_title：Pediatric transplantation

authors： Dharnidharka VR,Stevens G

更新日期：2005-10-01 00:00:00

abstract：:Autoimmune and allergic diseases cause morbidity and diminished quality of life in pediatric organ transplant recipients. We hypothesize that younger age at transplantation and immunosuppression regimen play a role in the development of immune-mediated disease following heart transplant. A single institution retrospec...

journal_title：Pediatric transplantation

authors： Mouledoux JH,Albers EL,Lu Z,Saville BR,Moore DJ,Dodd DA

更新日期：2014-03-01 00:00:00

abstract：:In many countries, adolescents can choose to register a deceased organ donation wish when they apply for a driver's license. They often receive education about deceased organ donation in order to make an informed choice. The objective of this review was to describe the effectiveness of school-based educational program...

journal_title：Pediatric transplantation

authors： Li AH,Rosenblum AM,Nevis IF,Garg AX

更新日期：2013-03-01 00:00:00

abstract：:Pediatric cardiac transplant has become increasingly frequent in the last decade and survival rates have improved remarkably. Outcome research on this population suggests that the majority of children have the capacity for healthy adaptation although 25-40% have been shown to have some type of psychiatric difficulties...

journal_title：Pediatric transplantation

authors： Weil CM,Rodgers S,Rubovits S

更新日期：2006-12-01 00:00:00

abstract：:Recipient lymphocytes are crucial for direct and indirect pathways of allorecognition. We proposed that the administration of alemtuzumab several weeks pretransplantation could eradicate peripheral lymphatic cells and promote donor-specific acceptance. This was a single-center, retrospective review of 101 consecutive ...

journal_title：Pediatric transplantation

authors： Kaabak MM,Babenko NN,Shapiro R,Maschan AA,Zokoev AK,Schekaturov SV,Vyunkova JN,Dymova OV

更新日期：2017-08-01 00:00:00

abstract：:There are limited published data on surveillance TBB for the identification of allograft rejection in infants after lung or heart-lung transplantation. We performed a retrospective review of children under one yr of age who underwent lung or heart-lung transplant at our institution. Since 2005, four infants were trans...

journal_title：Pediatric transplantation

authors： Hayes D Jr,Baker PB,Kopp BT,Kirkby S,Galantowicz M,McConnell PI,Astor TL

更新日期：2013-11-01 00:00:00

abstract：:To describe the prevalence and outcomes of renal transplantation in children with ID we performed a retrospective cohort analysis of all children receiving a first kidney-alone transplant in the UNOS dataset from 2008 to 2011. Recipients with definite, probable, and without ID were compared using chi-square tests. Kap...

journal_title：Pediatric transplantation

authors： Wightman A,Young B,Bradford M,Dick A,Healey P,McDonald R,Smith J

更新日期：2014-11-01 00:00:00

abstract：:Calcineurin inhibitors post-renal transplantation are recognized to cause tubulopathies in the form of hyponatremia, hyperkalemia, and acidosis. Sodium supplementation may be required, increasing medication burden and potentially resulting in poor compliance. Fludrocortisone has been beneficial in addressing tubulopat...

journal_title：Pediatric transplantation

authors： Ali SR,Shaheen I,Young D,Ramage I,Maxwell H,Hughes DA,Athavale D,Shaikh MG

更新日期：2018-03-01 00:00:00

abstract：:The aim of the study was to evaluate the cognitive and emotional development after pediatric liver transplantation. A total of 21 patients, aged 4-16.9 yr (median 9.6 yr) were tested 1-9 yr (median 4.2 yr) after the transplantation. The pretransplant diagnoses included biliary atresia (eight patients), various metabol...

journal_title：Pediatric transplantation

authors： Adebäck P,Nemeth A,Fischler B

更新日期：2003-10-01 00:00:00

abstract：:There is a limited supply of organs for all those who need them for survival. Thus, careful decisions must be made about who is listed for transplant. Studies show that manifesting genetic disease can impact listing eligibility. What has not yet been studied is the impact genetic risks for future disease have on a pat...

journal_title：Pediatric transplantation

authors： Graf M,Char D,Hanson-Kahn A,Magnus D

更新日期：2019-06-01 00:00:00