Impaired graft survival in pediatric renal transplant recipients with donor-specific antibodies detected by solid-phase assays.

abstract：:Bilateral nephrectomy prior to transplantation is indicated in some patients with end-stage renal disease. The indications for bilateral nephrectomy include persistent heavy proteinuria, refractory hypertension, and urinary tract infections. We report an eight-month-old baby with male pseudohermaphroditism and renal f...

journal_title：Pediatric transplantation

authors： Martínez Urrutia MJ,Olivares Arnal P,López Pereira P,Lobato Romera R,Alonso Melgar A,Jaureguizar Monereo E

更新日期：2007-03-01 00:00:00

abstract：:Total body irradiation and high-dose chemotherapy, applied as a preparatory regimen for bone marrow transplantation (BMT) in children with acute lymphoblastic leukemia (ALL), are particularly hazardous to the gonads and, in addition, can impair hypothalamo pituitary-gonadal control. Longitudinal data on pubertal devel...

journal_title：Pediatric transplantation

authors： Mayer EI,Dopfer RE,Klingebiel T,Scheel-Walter H,Ranke MB,Niethammer D

更新日期：1999-02-01 00:00:00

abstract：:RTx is currently the best treatment for children with ESRD. This study retrospectively analyzed the outcomes of growth after RTx using the pediatric-to-pediatric allocation strategy and some factors that may affect it. From March 2012 to August 2016, 8 en bloc and 38 single pediatric RTxs were performed at our center ...

journal_title：Pediatric transplantation

authors： Liu Z,Zhao WY,Zhang L,Zhu YH,Zeng L

更新日期：2019-02-01 00:00:00

abstract：:CKD is a major co-morbidity in pediatric lung transplant recipients. We report the prevalence of renal impairment post-lung transplant at a single center, using a modified, age-adjusted eGFR for the best approximation of true GFR, and investigated associations and possible predictors of decline in renal function post-...

journal_title：Pediatric transplantation

authors： Benden C,Kansra S,Ridout DA,Shaw NL,Aurora P,Elliott MJ,Marks SD

更新日期：2009-02-01 00:00:00

abstract：:Deficiency of the CD40L, expressed on the surface of T lymphocytes, is caused by mutations in the glycoprotein CD40L (CD154) gene. Resulting defective humoral and cellular responses cause a clinical presentation that includes recurrent sinopulmonary bacterial infections, opportunistic infections, sclerosing cholangiti...

journal_title：Pediatric transplantation

authors： Uygun DFK,Uygun V,Karasu GT,Daloğlu H,Öztürkmen SI,Çelmeli F,Törün SH,Özen A,Barış S,Aydıner EK,Yalçın K,Kılıç SÇ,Hazar V,Bingöl A,Yeşilipek A

更新日期：2020-09-01 00:00:00

abstract：:This study analyzes the data reported to the Korean Cord Blood Registry between 1994 and 2008, involving children and adolescents with non-malignant diseases. Sixty-five patients were evaluated in this study: SAA (n = 24), iBMFS, (n = 16), and primary immune deficiency/inherited metabolic disorder (n = 25). The CI of ...

journal_title：Pediatric transplantation

authors： Park M,Lee YH,Kang HR,Lee JW,Kang HJ,Park KD,Shin HY,Ahn HS,Baek HJ,Kook H,Hwang TJ,Lee JW,Chung NG,Cho B,Kim HK,Lee SH,Yoo KH,Sung KW,Koo HH,Koh KN,Im HJ,Seo JJ,Park JE,Lim YJ,Lyu CJ,Lee JM,Hah JO,K

更新日期：2014-03-01 00:00:00

abstract：:Studies are increasingly recognizing health-related quality of life (HRQOL) as a key pediatric outcome in both clinical and research settings and an essential health outcome measure to assess the effectiveness of medical treatment. However, it has not yet been studied among the healthy siblings of kidney transplant re...

journal_title：Pediatric transplantation

authors： Velasco J,Ferraris JR,Eymann A,Ghezzi LFR,Coccia PA,Ferraris V

更新日期：2020-08-01 00:00:00

abstract：:We report a case of a patient who received a bilateral lung transplant for end-stage lung disease secondary to Gauchers type-1 disease with no evidence of recurrence of the disease in the transplanted lung. ...

journal_title：Pediatric transplantation

authors： Rao AR,Parakininkas D,Hintermeyer M,Segura AD,Rice TB

更新日期：2005-04-01 00:00:00

abstract：:Many pediatric centers utilize a variety of protocols including preemptive plasmapheresis to prevent the recurrence of FSGS post-transplant. But the effectiveness of this expensive, time-consuming process of plasmapheresis in the prevention of FSGS recurrence is still unclear. We retrospectively reviewed all pediatric...

journal_title：Pediatric transplantation

authors： Verghese PS,Rheault MN,Jackson S,Matas AJ,Chinnakotla S,Chavers B

更新日期：2018-05-01 00:00:00

abstract：:Recurrent FSGS is a major challenge in the field of nephrology. To clarify the role of NPHS2 defects in the pathogenesis of FSGS recurrence, we sequenced all eight exons of NPHS2 in 11 Japanese pediatric FSGS patients with or without post-transplant recurrence. All patients had biopsy-proven primary FSGS, had no famil...

journal_title：Pediatric transplantation

authors： Furue T,Hattori M,Tsukaguchi H,Kitamura A,Oomori T,Ogino D,Nakakura H,Ashida A,Miura K,Hisano M,Takahashi K,Chikamoto H,Akioka Y,Sakano T

更新日期：2008-05-01 00:00:00

abstract：:Tacrolimus-based immunosuppression in pediatric liver transplant recipients is known to be associated with EGID. Our goal was to determine the incidence, risk factors, and characteristics of EGID in our pediatric liver transplantation program. This study was a retrospective analysis of 38 pediatric liver transplant re...

journal_title：Pediatric transplantation

authors： Lee JH,Park HY,Choe YH,Lee SK,Lee SI

更新日期：2007-08-01 00:00:00

abstract：:Dysregulation of genes involved in the cell cycle such as TP53, P21, P16, and PTEN plays a key role in oncogenesis. We have earlier reported increased expression of the TP53 encoded protein p53, in bone marrow samples from pediatric patients with more aggressive, rare chronic myeloid malignancies. The aim of this stud...

journal_title：Pediatric transplantation

authors： Mattsson K,Honkaniemi E,Barbany G,Gustafsson B

更新日期：2015-11-01 00:00:00

abstract：:INFVA is an important cause of pulmonary infections in patients receiving BMT, and is associated with considerable morbidity and mortality for a readily preventable and treatable infection. Few studies have addressed the impact of the new neuraminidase inhibitors in the prognosis of influenza after BMT. The aim of thi...

journal_title：Pediatric transplantation

authors： Mellouli F,Ouederni M,Dhouib N,Hajkacem MA,Slim A,Bejaoui M

更新日期：2010-03-01 00:00:00

abstract：:FA is an autosomal recessive disorder characterized by small stature and renal abnormalities. FA can lead to progressive bone marrow failure, myelodysplastic syndrome, or acute leukemia. Using a multidisciplinary team approach, we managed a 3-yr-old boy with FA who simultaneously developed renal and hematopoietic fail...

journal_title：Pediatric transplantation

authors： Vincent CL,Primack WA,Hipps J,Kasow KA

更新日期：2016-02-01 00:00:00

abstract：:We report a case of EBV encephalitis in a seven-yr-old child with Ph+ ALL. Two months after an allogeneic HSCT from his HLA mismatched mother, the patient showed an altered sensorium, generalized seizures, and a left hemiparesis. Brain MRI demonstrated multiple lesions highly suggestive for viral encephalitis. Blood a...

journal_title：Pediatric transplantation

authors： Barberi W,Perrone S,Iori AP,Torelli GF,Testi AM,Moleti ML,Ceglie T,Papoff P,Caresta E,Antonelli M,Gianno F,Melone A,Badiali M,Giangaspero F,Foà R,Gentile G

更新日期：2015-02-01 00:00:00

abstract：:We sought to examine the relationship between liver transplant-related total cost, patient outcome, and hospital resource utilization at freestanding children's hospitals. Using the PHIS database, a retrospective study of 374 patients that underwent liver transplantation at 15 freestanding children's hospitals from Ju...

journal_title：Pediatric transplantation

authors： Minneman JA,Grijalva JL,LaQuaglia MJ,Kim HB,Rangel SJ,Vakili K

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND/AIM:Several PK studies have shown that most pediatric patients may require higher doses on a mg/kg basis compared to adults to attain similar therapeutic trough concentrations. The aim of this study was to compare the efficacy and safety of three times daily to twice a day dosing of tacrolimus in pediatric k...

journal_title：Pediatric transplantation

authors： Alabdulkarim Z,Al-Jedai A,Alkortas D,Alhasan K,Devol E

更新日期：2020-09-01 00:00:00

abstract：:The role of unrelated donor HSCT for children with de novo AML in CR1 is controversial. We performed this study to investigate the feasibility of unrelated donor HSCT who initially had intermediate- or high-risk cytogenetics. We retrospectively reviewed medical records of patients with AML who received unrelated HSCT ...

journal_title：Pediatric transplantation

authors： Park EG,Yi ES,Choi YB,Sung KW,Koo HH,Yoo KH

更新日期：2019-06-01 00:00:00

abstract：:Paediatric HR T-cell ALL demonstrates dismal prognosis with chemotherapy, and poor outcomes could be improved with allo-SCT. HID-SCT is an almost immediately available choice; however, few studies have focused on the outcomes of HID-SCT for paediatric HR T-ALL. Forty-eight consecutive HR T-ALL children who underwent H...

journal_title：Pediatric transplantation

authors： Xu ZL,Huang XJ,Liu KY,Chen H,Zhang XH,Han W,Chen YH,Wang FR,Wang JZ,Wang Y,Chen Y,Yan CH,Xu LP

更新日期：2016-06-01 00:00:00

abstract：:The clinical significance and prognostic impact of IRFR in pediatric recipients of haploidentical SCT are not clearly understood. Therefore, we attempted to determine how IRFR affects clinical outcomes in children. Clinical data from 100 consecutive pediatric patients (60 boys and 40 girls; median age, 12 yr [range, 2...

journal_title：Pediatric transplantation

authors： Chen Y,Huang XJ,Liu KY,Chen H,Chen YH,Zhang XH,Wang FR,Han W,Wang JZ,Wang Y,Yan CH,Zhang YY,Sun YQ,Xu LP

更新日期：2015-12-01 00:00:00

abstract：:Cardiac transplantation for children with end-stage cardiac disease with no other medical or surgical options is now standard. The number of children in need of cardiac transplant continues to exceed the number of donors considered "acceptable." Therefore, there is an urgent need to understand which recipients are in ...

journal_title：Pediatric transplantation

authors： Denfield SW,Azeka E,Das B,Garcia-Guereta L,Irving C,Kemna M,Reinhardt Z,Thul J,Dipchand AI,Kirk R,Davies RR,Miera O

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:To study the characteristics and the predictors of survival observed in our pediatric live-donor renal transplant recipients with an allograft that functioned for more than 10 yr. METHODS:One hundred fifteen children underwent renal transplantation between 1976 and 1995. Of these, 30 had functioning allogra...

journal_title：Pediatric transplantation

authors： El-Husseini AA,Foda MA,Osman YM,Sobh MA

更新日期：2006-05-01 00:00:00

abstract：:DIDS is a unique form of combined immune deficiency characterized by an unusual susceptibility to cutaneous viral infections, severe allergies with eosinophilia and elevated immunoglobulin E titers, autoimmunity, and cancer. HSCT is considered the standard of care for this deadly disease. We have retrospectively analy...

journal_title：Pediatric transplantation

authors： Uygun DFK,Uygun V,Reisli İ,Keleş S,Özen A,Yılmaz M,Sayar EH,Daloğlu H,Öztürkmen SI,Çakı S,Karasu GT,Yeşilipek A

更新日期：2017-11-01 00:00:00

abstract：:An increased frequency of infections has been reported in patients with chronic liver disease. The tendency of patients in this population to acquire UTI is not completely understood. We aimed at investigating the incidence of UTI in children with cirrhosis, before liver transplantation. Twenty-six children (9 girls, ...

journal_title：Pediatric transplantation

authors： Baskin E,Ozçay F,Sakalli H,Agras PI,Karakayali H,Canan O,Haberal M

更新日期：2007-06-01 00:00:00

abstract：:Cystic fibrosis (CF) is an inherited disease with a defect in epithelial chloride transport that results in a multisystem disease. Although pulmonary disease remains the primary cause of morbidity and mortality, focal biliary cirrhosis and portal hypertension may develop in up to 8% of these patients. Liver transplant...

journal_title：Pediatric transplantation

authors： Henn C,Kapellen T,Prenzel F,Siekmeyer M,Hau HM,Kiess W,Bartels M

更新日期：2014-02-01 00:00:00

abstract：:HHV type 6 has been reported with enhanced pathogenicity in immunocompromised patients. Herein, we report about a two-yr-old girl who experienced primary HHV 6 infection after liver transplantation. She clinically presented with graft rejection and necrotic hepatitis as well as high fever, pneumonitis with respiratory...

journal_title：Pediatric transplantation

authors： Dohna-Schwake C,Fiedler M,Gierenz N,Gerner P,Ballauf A,Breddemann A,Läer S,Baba HA,Hoyer PF

更新日期：2011-09-01 00:00:00

abstract：:Depression is common in pediatric chronic kidney disease (CKD) patients. Depression is associated with inferior long-term outcomes. There is a paucity of studies that evaluate depression and possible associated factors in children and adolescents requiring renal replacement therapy (RRT). Cross-sectional study using C...

journal_title：Pediatric transplantation

authors： Rodriguez Cuellar CI,García de la Puente S,Hernández Moraria J,Bojórquez Ochoa A,Filler G,Zaltzman Grishevich S

更新日期：2019-12-01 00:00:00

abstract：:Plasma cell-rich acute cellular rejection of a transplanted kidney is described in association with the identification of serum antibody to the red cell Kidd antigen, Jk-b, which is also found in the kidney. This antibody was formed without a history of a recent blood transfusion or exposure to intravenous immunoglobu...

journal_title：Pediatric transplantation

authors： Hamilton MS,Singh V,Warady BA

更新日期：2006-12-01 00:00:00

abstract：:Early graft loss and poor graft function limit the use of kidneys from infant donors. Six en bloc kidney transplantations were performed from infant donors younger than 10 months into pediatric recipients between November 2012 and September 2015 at our center. We retrospectively analyzed recipient and donor demographi...

journal_title：Pediatric transplantation

authors： Wang HY,Li J,Liu LS,Deng RH,Fu Q,Ko DS,Zhang HX,Deng SX,Wang CX

更新日期：2017-03-01 00:00:00

abstract：:The emergence of oseltamivir-resistant 2009 H1N1 influenza virus (conferred by the H275Y substitution in NA) during therapy or prophylaxis in immunocompromised patients is a serious concern. The optimal therapy for immunosuppressed patients with oseltamivir-resistant 2009 H1N1 influenza virus is unknown and few option...

journal_title：Pediatric transplantation

authors： Shetty AK,Ross GA,Pranikoff T,Gubareva LV,Sechrist C,Guirand DM,Abramson J,Lin JJ

更新日期：2012-08-01 00:00:00