Infusion-related febrile reaction after haploidentical stem cell transplantation in children is associated with higher rates of engraftment syndrome and acute graft-versus-host disease.

abstract：BACKGROUND:The hybrid stage 1 palliation for hypoplastic left heart syndrome (HLHS) was first described in 1993 as a bridge to heart transplant for HLHS. There are limited data on this strategy as primary heart transplantation for HLHS has become less common. METHODS:This is an observational, single-center study compa...

journal_title：Pediatric transplantation

authors： Morray BH,Albers EL,Jones TK,Kemna MS,Permut LC,Law YM

更新日期：2018-12-01 00:00:00

abstract：:CVD is a major cause of morbidity and mortality in pediatric patients with CKD. It is unclear whether vascular abnormalities in these patients are reversible, and if transplantation portends salutary effects on arterial function. We compared FMD, PWV, AI75, and CIMT in 15 dialysis (D), 14 transplant patients (T), and ...

journal_title：Pediatric transplantation

authors： Tawadrous H,Kamran H,Salciccioli L,Schoeneman MJ,Lazar J

更新日期：2012-08-01 00:00:00

abstract：:CGD is a rare primary immunodeficiency with high mortality rates when treated conventionally, especially for the X-chromosome-linked form. HSCT is the only curative therapy for CGD; however, haploidentical transplantation in CGD is rare. Here, we report a case of X-linked CGD treated successfully by haploidentical HSC...

journal_title：Pediatric transplantation

authors： Zhou L,Dong LJ,Gao ZY,Yu XJ,Lu DP

更新日期：2017-02-01 00:00:00

abstract：:Live viral vaccines have historically been avoided in children after solid organ transplantation. Multiple reports of safety and immunogenicity, largely in the pediatric liver transplant population, have led to a reconsideration of this recommendation. Here, we report the case of a 4-year-old boy who inadvertently rec...

journal_title：Pediatric transplantation

authors： Bobrowski AE,Muller WJ

更新日期：2020-06-01 00:00:00

abstract：:Total body irradiation and high-dose chemotherapy, applied as a preparatory regimen for bone marrow transplantation (BMT) in children with acute lymphoblastic leukemia (ALL), are particularly hazardous to the gonads and, in addition, can impair hypothalamo pituitary-gonadal control. Longitudinal data on pubertal devel...

journal_title：Pediatric transplantation

authors： Mayer EI,Dopfer RE,Klingebiel T,Scheel-Walter H,Ranke MB,Niethammer D

更新日期：1999-02-01 00:00:00

abstract：:There are few studies on invasive pneumococcal disease in pediatric transplant recipients. Given this fact plus the advent of pneumococcal conjugate vaccines, we conducted a retrospective study at a major pediatric transplant center. The objectives were to determine the incidence and outcomes of invasive pneumococcal ...

journal_title：Pediatric transplantation

authors： Tran L,Hébert D,Dipchand A,Fecteau A,Richardson S,Allen U

更新日期：2005-04-01 00:00:00

abstract：:  FSGS has a high recurrence rate after renal transplantation. To examine the effects of the use of preemptive and post-transplant PP on recurrence and graft outcome, we conducted a retrospective study on 34 pediatric patients (mean age 13±5 yr) with biopsy-proven pretransplant FSGS and who underwent a renal transplan...

journal_title：Pediatric transplantation

authors： Gonzalez E,Ettenger R,Rianthavorn P,Tsai E,Malekzadeh M

更新日期：2011-08-01 00:00:00

abstract：:Ingestion of rare-earth magnet beads in children has been a public health concern. The potential risk of swallowing multiple magnets is related to magnet attraction to each other, resulting in serious gastrointestinal complications, such as entero-enteric fistula formation, peritonitis, bowel ischemia or necrosis, bow...

journal_title：Pediatric transplantation

authors： Miri A,Nakayuenyongsuk W,Vargas L,Langnas A,Vo HD

更新日期：2020-11-20 00:00:00

abstract：:Infants listed for heart transplantation experience high waitlist and early post-transplant mortality, and thus, optimal allocation of scarce donor organs is required. Unfortunately, the creation and validation of multivariable regression models to identify risk factors and generate individual-level predictions are ch...

journal_title：Pediatric transplantation

authors： Chen CK,Manlhiot C,Mital S,Schwartz SM,Van Arsdell GS,Caldarone C,McCrindle BW,Dipchand AI

更新日期：2018-03-01 00:00:00

abstract：:In the past 20 yr, a dramatic improvement has been achieved in the outcome of children with hepatoblastoma by combining cisplatin based chemotherapy and surgery. Treatment of patients in the USA is an exception to the rule that all patients should receive neoadjuvant chemotherapy. It is paramount that surgical resecti...

journal_title：Pediatric transplantation

authors： Otte JB,de Ville de Goyet J,Reding R

更新日期：2005-10-01 00:00:00

abstract：:Tailoring graft size to small paediatric recipients is a challenge. We have developed a reduced left lateral segment as an alternative to monosegment transplantation for small size recipients. Since November 2000, 89 children have been transplanted with 100 deceased donor liver grafts in our unit. Our median patient a...

journal_title：Pediatric transplantation

authors： Attia MS,Stringer MD,McClean P,Prasad KR

更新日期：2008-09-01 00:00:00

abstract：:Methylmalonic acidemia with complete mutase deficiency (mut(0) type) is an inborn error of metabolism with high mortality and morbidity. LT has been suggested to be a solution to this disease, but elevation of urinary and blood MMA was still observed after LT. In this study, we measured dry blood spot MMA and its prec...

journal_title：Pediatric transplantation

authors： Chen PW,Hwu WL,Ho MC,Lee NC,Chien YH,Ni YH,Lee PH

更新日期：2010-05-01 00:00:00

abstract：:Even if kidney graft survival has improved during the last decades, sensitized pediatric patients are an emerging problem. We describe a 17-yr-old male who lost his first graft due to chronic rejection becoming hyperimmunized (CDC PRA 99.61%). A desensitization protocol based on high-dose IVIG, PP, and two Mabthera(®)...

journal_title：Pediatric transplantation

authors： Ghirardo G,Benetti E,Poli F,Vidal E,Della Vella M,Cozzi E,Murer L

更新日期：2014-02-01 00:00:00

abstract：:MCs are important effector cells in a broad range of immune responses. Their role in liver allograft rejection is not clear. Twenty-one liver transplant recipients (mean age +/- s.d.; 10.2 +/- 4.1 yr) who experienced a rejection episode are included in this study. Biopsy specimens from normal livers (allograft biopsy ...

journal_title：Pediatric transplantation

authors： Arikan C,Nart D,Kilic M,Yuksekkaya HA,Aydogdu S

更新日期：2008-05-01 00:00:00

abstract：:Renal transplantation is the treatment of choice for children with ESRD offering advantages of improved survival, growth potential, cognitive development, and quality of life. The aim of our study was to compare the outcomes of LDKT vs DDKT performed in children at a single center. Retrospective chart review of pediat...

journal_title：Pediatric transplantation

authors： Pérez-Bertólez S,Barrero R,Fijo J,Alonso V,Ojha D,Fernández-Hurtado MÁ,Martínez J,León E,García-Merino F

更新日期：2017-05-01 00:00:00

abstract：:Mycoplasma pneumoniae has rarely been reported in renal transplant recipients. We present the case of a 10-yr-old boy with a six-month history of chronic cough, recurrent pyrexia, and weight loss three yr after RTx. The patient's post-transplant course was complicated by recurrence of NS that resolved with plasmaphere...

journal_title：Pediatric transplantation

authors： Schwerk N,Hartmann C,Baumann U,Pape L,Ehrich JH,Hansen G

更新日期：2010-05-01 00:00:00

abstract：:Children receiving HCT loose protective immunity to vaccines received pre-HCT. Therefore, revaccination post-HCT is of major importance. In Denmark, a vaccination schedule with fewer doses post-HCT has been used, including two doses for diphtheria, tetanus, polio, measles, mumps, and rubella, and one dose only for Hae...

journal_title：Pediatric transplantation

authors： Jensen L,Poulsen A,Nygaard U,Scheike T,Riis MS,Pedersen FK,Heilmann C

更新日期：2020-02-01 00:00:00

abstract：:We hypothesized that use of Schwartz formula underestimates the prevalence of CKD in PHT recipients. This study determined the prevalence and risk factors for CKD in PHT using novel methods-serum cystatin C, CKiD formula, Revised Schwartz formula, s- and u-NGAL. Serum BUN, creatinine, cystatin C and s- and u-NGAL were...

journal_title：Pediatric transplantation

authors： Abraham BP,Frazier EA,Morrow WR,Blaszak RT,Devarajan P,Mitsnefes M,Bryant JC,Sachdeva R

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Studies of HRQoL after kidney transplant have yielded conflicting results. We sought to assess the impact of kidney transplant on HRQoL. METHODS:We performed a retrospective study using the PedsQL3.0ESRD module during dialysis and at 3 and 12 months following kidney transplant in 56 recipients. For the enti...

journal_title：Pediatric transplantation

authors： Wightman A,Bradford MC,Smith J

更新日期：2019-03-01 00:00:00

abstract：:Combined enzyme replacement therapy (ERT) and stem cell transplant (SCT) were done for a two year old boy with severe Hurler syndrome(HS) with the aim to decrease transplant related complications. He tolerated both the procedures well without any major complications. Urine glycosaminoglycans (GAGs) decreased post-tran...

journal_title：Pediatric transplantation

authors： Soni S,Hente M,Breslin N,Hersh J,Whitley C,Cheerva A,Bertolone S

更新日期：2007-08-01 00:00:00

abstract：:BWS is one of the most well-known somatic overgrowth syndromes, which is characterized by macroglossia, organomegaly, abdominal wall defects, and predisposition to embryonal tumors, such as Wilms' tumor, hepatoblastoma, and adrenocortical carcinoma. We report a case of BWS in a girl with unresectable hepatoblastoma, w...

journal_title：Pediatric transplantation

authors： Sasaki K,Kasahara M,Fukuda A,Shigeta T,Tanaka H,Nakagawa S,Mitsui K,Harada R,Nakagawa A

更新日期：2010-11-01 00:00:00

abstract：:Nephrotic syndrome is characterized by proteinuria, hypoalbuminemia, and general edema. These symptoms may persist in children who reach ESRD, which is unfavorable for the patient's allograft outcome. In addition, this may hamper early diagnosis of a relapse after transplantation. Surgical bilateral nephrectomy is oft...

journal_title：Pediatric transplantation

authors： Vos E,Koster-Kamphuis L,van de Kar NCAJ,Bootsma-Robroeks CMHHT,Cornelissen EAM,Schreuder MF

更新日期：2020-06-01 00:00:00

abstract：:Impact of pretransplant splenectomy in patients with beta-thalassemia major undergoing an allogeneic SCT has never been addressed. Twenty-seven class III patients (29 transplants) had a pretransplant splenectomy. The outcome of these 29 transplants was compared with 76 transplants in class III who did not have a splen...

journal_title：Pediatric transplantation

authors： Mathews V,George B,Lakshmi KM,Viswabandya A,John JM,Sitaram U,Daniel D,Chandy M,Srivastava A

更新日期：2009-03-01 00:00:00

abstract：:Portal vein aneurysms are very rare and represent <3% of all venous aneurysms. They can be congenital or acquired. Most patients do not have liver disease at diagnosis. Although uncommon, portal vein aneurysm has been described after liver transplant. We report the case of a six-yr-old girl who presented with an aneur...

journal_title：Pediatric transplantation

authors： Molinares B,Alvarez S,García V,Sepúlveda ME,Yepes NL,Peláez S

更新日期：2013-02-01 00:00:00

abstract：:Patients with defects in the ATP6AP1 gene have rarely been described. ATP6AP1-related disorders are a subtype of CDG, which result in enzyme deficiencies affecting multiple organ systems ranging from mild to life-threatening. Of the 13 patients described, all had hepatopathy, but this is the first case to be successfu...

journal_title：Pediatric transplantation

authors： Gumm AJ,Basel DG,Thakrar P,Suchi M,Telega G

更新日期：2020-12-01 00:00:00

abstract：:Cardiac transplantation for children with end-stage cardiac disease with no other medical or surgical options is now standard. The number of children in need of cardiac transplant continues to exceed the number of donors considered "acceptable." Therefore, there is an urgent need to understand which recipients are in ...

journal_title：Pediatric transplantation

authors： Denfield SW,Azeka E,Das B,Garcia-Guereta L,Irving C,Kemna M,Reinhardt Z,Thul J,Dipchand AI,Kirk R,Davies RR,Miera O

更新日期：2020-05-01 00:00:00

abstract：:To evaluate the effects of gender on HRQOL and overall health status in our pediatric kidney transplants. We performed a cross-sectional study in 77 children who received living renal allo-transplants in our center between 1981 and 2003. The patients were given a questionnaire at a post-transplant visit. After complet...

journal_title：Pediatric transplantation

authors： El-Husseini A,Hassan R,Sobh M,Ghoneim M

更新日期：2010-03-01 00:00:00

abstract：:Germline GATA2 mutations have been associated with a vast array of clinical manifestations, as well as hematological deficiencies and a propensity to AML or MDS. We present two cases of pediatric AML/MDS with underlying GATA2 mutations who underwent a successful umbilical cord hematopoietic stem cell transplantation u...

journal_title：Pediatric transplantation

authors： Mallhi K,Dix DB,Niederhoffer KY,Armstrong L,Rozmus J

更新日期：2016-11-01 00:00:00

abstract：:HPS is defined as arterial hypoxemia because of pulmonary vasodilation as a result of cirrhotic or non-cirrhotic portal hypertension. This report describes a teenager with HPS because of primary sclerosing cholangitis/autoimmune hepatitis overlap syndrome requiring OLT. HPS resolved completely within three months of O...

journal_title：Pediatric transplantation

authors： Rajwal SR,Davison SM,Prasad R,Brownlee K,McClean P

更新日期：2007-12-01 00:00:00

abstract：:This review focuses on active clinical research in pediatric liver transplantation with special emphasis on areas that could benefit from studies utilizing the SPLIT infrastructure and data repository. Ideas were solicited by members of the SPLIT Research Committee and sections were drafted by members of the committee...

journal_title：Pediatric transplantation

authors： Alonso EM,Ng VL,Anand R,Anderson CD,Ekong UD,Fredericks EM,Furuya KN,Gupta NA,Lerret SM,Sundaram S,Tiao G,Studies of Pediatric Liver Transplantation (SPLIT) Research Group.

更新日期：2013-08-01 00:00:00