Abstract:
:CVD is a major cause of morbidity and mortality in pediatric patients with CKD. It is unclear whether vascular abnormalities in these patients are reversible, and if transplantation portends salutary effects on arterial function. We compared FMD, PWV, AI75, and CIMT in 15 dialysis (D), 14 transplant patients (T), and 15 controls (C), and their associations with cardiovascular risk factors. There was stepwise lower FMD (p < 0.001), higher AI75 (p < 0.001), higher PWV (p = 0.01), and higher CIMT SDS for age (p = 0.03) and height (p = 0.006) in the D group than T and C groups. FMD, PWV, and CIMT were unrelated to dialysis duration or time from transplantation. On multivariate analysis, group status was independently associated with FMD (β = 3.15, p = 0.002), AI75 (β = -5.95, p = 0.01), PWV (β = -0.57, p = 0.07) and CIMT (β = -0.02, p = 0.04) and CIMT SDS for height (β = -0.541, p = 0.009). FMD is lower and AI75, PWV and CIMT are higher in pediatric patients maintained on D than T/C. T patients have similar AI75, PWV and CIMT to C although FMD remains reduced. These findings suggest that transplantation stabilizes or improves CKD associated arteriopathy.
journal_name
Pediatr Transplantjournal_title
Pediatric transplantationauthors
Tawadrous H,Kamran H,Salciccioli L,Schoeneman MJ,Lazar Jdoi
10.1111/j.1399-3046.2012.01721.xsubject
Has Abstractpub_date
2012-08-01 00:00:00pages
480-5issue
5eissn
1397-3142issn
1399-3046journal_volume
16pub_type
杂志文章abstract::Controversy exists over whether PHTN in heart transplant candidates increases post-transplant mortality. We performed analysis of data reported to UNOS for children who underwent primary heart transplantation for cardiomyopathy from January 1994 to June 2010. Patients were divided into two groups depending on their pr...
journal_title:Pediatric transplantation
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更新日期:2012-06-01 00:00:00
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更新日期:2020-12-01 00:00:00
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journal_title:Pediatric transplantation
pub_type: 杂志文章
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更新日期:2009-11-01 00:00:00
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journal_title:Pediatric transplantation
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journal_title:Pediatric transplantation
pub_type: 杂志文章
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更新日期:2014-02-01 00:00:00
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journal_title:Pediatric transplantation
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doi:10.1111/j.1399-3046.2009.01281.x
更新日期:2010-09-01 00:00:00
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journal_title:Pediatric transplantation
pub_type: 杂志文章
doi:10.1111/j.1399-3046.2007.00767.x
更新日期:2007-11-01 00:00:00
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journal_title:Pediatric transplantation
pub_type: 杂志文章
doi:10.1111/j.1399-3046.2007.00842.x
更新日期:2008-02-01 00:00:00
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journal_title:Pediatric transplantation
pub_type: 杂志文章
doi:10.1111/j.1399-3046.2010.01469.x
更新日期:2011-05-01 00:00:00
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journal_title:Pediatric transplantation
pub_type: 杂志文章
doi:10.1111/petr.12585
更新日期:2015-11-01 00:00:00
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journal_title:Pediatric transplantation
pub_type: 杂志文章
doi:10.1111/j.1399-3046.2007.00753.x
更新日期:2007-12-01 00:00:00
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journal_title:Pediatric transplantation
pub_type: 杂志文章
doi:10.1111/j.1399-3046.2010.01354.x
更新日期:2010-11-01 00:00:00
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journal_title:Pediatric transplantation
pub_type: 杂志文章
doi:10.1111/petr.12450
更新日期:2015-06-01 00:00:00
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journal_title:Pediatric transplantation
pub_type: 杂志文章
doi:10.1111/j.1399-3046.2007.00819.x
更新日期:2008-05-01 00:00:00
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journal_title:Pediatric transplantation
pub_type: 杂志文章
doi:10.1111/j.1399-3046.2008.01009.x
更新日期:2009-08-01 00:00:00
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journal_title:Pediatric transplantation
pub_type: 杂志文章
doi:10.1111/petr.13203
更新日期:2018-08-01 00:00:00
abstract::From June 1985 to December 1998, 173 pediatric renal transplants were carried out in 170 patients at our center. From this pool, 73 patients (34 males and 39 females) with a follow-up of 48 months were examined. In all patients, ureteroneocystostomy was performed according to the Lich-Grégoire procedure. All patients ...
journal_title:Pediatric transplantation
pub_type: 杂志文章
doi:10.1034/j.1399-3046.1999.00017.x
更新日期:1999-08-01 00:00:00
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journal_title:Pediatric transplantation
pub_type: 杂志文章
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更新日期:2003-01-01 00:00:00
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pub_type:
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更新日期:2020-11-20 00:00:00
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pub_type: 杂志文章
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更新日期:2011-03-01 00:00:00
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journal_title:Pediatric transplantation
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更新日期:2004-06-01 00:00:00
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journal_title:Pediatric transplantation
pub_type:
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更新日期:2007-12-01 00:00:00
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journal_title:Pediatric transplantation
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更新日期:2015-02-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2020-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:2012-05-01 00:00:00
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journal_title:Pediatric transplantation
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1998-05-01 00:00:00
abstract::This retrospective case series reviews our center's experience with sirolimus and a CNI as alternative therapy for the treatment of PTAH. It also characterizes regulatory T cells (Tregs) in PTAH. LT recipients with PTAH who had received or were receiving treatment with sirolimus were retrospectively identified (n = 12...
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pub_type: 杂志文章
doi:10.1111/j.1399-3046.2012.01648.x
更新日期:2012-03-01 00:00:00