Successful resolution of inflammation and increased regulatory T cells in sirolimus-treated post-transplant allograft hepatitis.

abstract：:Data from 997 pediatric LT recipients were used to model demographic and medical variables as predictors of lower levels of HRQOL. Data were collected through SPLIT FOG project. Patients were between 2 and 18 yr of age and survived LT by at least 12 months. Parents and children (age ≥ 8 yr) completed PedsQL™ 4.0 Gener...

journal_title：Pediatric transplantation

authors： Alonso EM,Martz K,Wang D,Yi MS,Neighbors K,Varni JW,Bucuvalas JC,Studies of Pediatric Liver Transplantation (SPLIT) Functional Outcomes Group (FOG).

更新日期：2013-11-01 00:00:00

abstract：:HTN after renal transplantation is associated with cardiovascular morbidity. ABPM allows diagnosis of masked HTN and isolated nocturnal HTN. Longitudinal ABPM data in children post-transplant are limited. ABPM was performed in children post-transplant and repeated in 6-12 months. BP indices were used to determine the ...

journal_title：Pediatric transplantation

authors： Pais P,Dello Strologo L,Iyengar A,Velusamy V,Greenbaum LA

更新日期：2020-06-01 00:00:00

abstract：:A major risk faced by bone-marrow and solid organ transplant patients is the development of post-transplant lymphoproliferative disease or post-transplant lymphoma (PTLD). In pediatric transplantation, PTLD onset is often associated with a rapid rise in Epstein-Barr virus (EBV) load in peripheral blood mononuclear cel...

journal_title：Pediatric transplantation

authors： Orentas RJ,Schauer DW Jr,Ellis FW,Walczak J,Casper JT,Margolis DA

更新日期：2003-08-01 00:00:00

abstract：:This systematic review was designed to find out optimal tacrolimus dose in pediatrics according to their CYP3A5*1 genotype by performing meta-analysis. PubMed, Scopus, ISI web of Science, ProQuest, Cochrane library, and clinicaltrail.gov were systematically searched to find studies in which tacrolimus dose and/or bloo...

journal_title：Pediatric transplantation

authors： Hendijani F,Azarpira N,Kaviani M

更新日期：2018-06-19 00:00:00

abstract：:Historically inability to achieve portal inflow to the liver allograft operatively was felt to be a contraindication to orthotopic liver transplantation (OLTx). Cavoportal hemi transposition has been utilized more recently in adult OLTx recipients but rarely in pediatric recipients. Here we report the case of a 10-mon...

journal_title：Pediatric transplantation

authors： Verran D,Crawford M,Stormon M,Shun A

更新日期：2004-08-01 00:00:00

abstract：:Graft-vs-host disease (GVHD) is one of the most difficult problems in stem cell transplantation. It is best considered in the context of the normal immune response. The role of the immune system is to identify and eliminate foreign antigens. In the case of GVHD, the antigens are minor histocompatibility antigens (mHA)...

journal_title：Pediatric transplantation

authors： Antin JH

更新日期：2005-12-01 00:00:00

abstract：:Intestinal transplant recipients are at risk of micronutrient deficiency due to the slow process of post-transplant adaptation. Another contributing factor is calcineurin inhibitor-induced renal tubular dysfunction. Patients are typically supplemented with micronutrients during PN; however, the risk of deficiency may ...

journal_title：Pediatric transplantation

authors： Ubesie AC,Cole CR,Nathan JD,Tiao GM,Alonso MH,Mezoff AG,Henderson CJ,Kocoshis SA

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Little data exist on immunosuppressive drug absorption in children with short bowel syndrome and intestinal failure associated liver disease (SBS-IFALD). AIM:To evaluate the absorption of immunosuppressive medications in children with SBS-IFALD undergoing isolated liver transplantation (iLTx). METHODS:A re...

journal_title：Pediatric transplantation

authors： Olio DD,Gupte G,Sharif K,Murphy MS,Lloyd C,McKiernan PJ,Kelly DA,Beath SV

更新日期：2006-09-01 00:00:00

abstract：:This study aims to evaluate BMD and bone biomarkers and to investigate the effects of immunosuppressives on bone disease after RTx. Thirty-three RTR aged 16.7 ± 3.7 yr and healthy controls (n = 32) were enrolled. There was no difference between pre-RTx BMD and BMD at the time of study (45.9 ± 30.9 months after RTx), w...

journal_title：Pediatric transplantation

authors： Büyükkaragöz B,Bakkaloglu SA,Kandur Y,Isiyel E,Akcaboy M,Buyan N,Hasanoglu E

更新日期：2015-06-01 00:00:00

abstract：:We examined SCC development of 24 FA patients, who received HSCT from HLA-matched relatives. In our BMT center, we applied low-dose CY + LFI + ATG (n:13) as conditioning regimen for FA patients between 1992 and 1999, and CY + BU + ATG (n:11) between 1999 and 2002. The aim of this study was to investigate SCC developme...

journal_title：Pediatric transplantation

authors： Anak S,Yalman N,Bilgen H,Sepet E,Deviren A,Gürtekin B,Tunca F,Başaran B

更新日期：2020-06-01 00:00:00

abstract：:Drowning, a common cause of death in the pediatric population, is a potentially large donor pool for OLT. Anecdotally, transplant centers have deemed these organs high risk over concerns for infection and graft dysfunction. We theorized drowned donor liver allografts do not portend worse outcomes and therefore should ...

journal_title：Pediatric transplantation

authors： Kumm KR,Galván NTN,Koohmaraie S,Rana A,Kueht M,Baugh K,Hao L,Yoeli D,Cotton R,O'Mahony CA,Goss JA

更新日期：2017-09-01 00:00:00

abstract：:In their provocative paper, "Lung transplantation and survival in children with cystic fibrosis," Liou and colleagues state that "Prolongation of life by means of lung transplantation should not be expected in children with cystic fibrosis. A prospective, randomized trial is needed to clarify whether and when patients...

journal_title：Pediatric transplantation

authors： Sweet SC,Aurora P,Benden C,Wong JY,Goldfarb SB,Elidemir O,Woo MS,Mallory GB Jr,International Pediatric Lung Transplant Collaborative.

更新日期：2008-03-01 00:00:00

abstract：:We reviewed 112 pediatric renal transplant recipients to document the rate of medication non-adherence (NA) and to examine the relationships between NA, comorbid psychiatric illness, and the outcome variables of acute and chronic rejection and graft loss. A total of 32.5% of subjects had clinically significant NA with...

journal_title：Pediatric transplantation

authors： Shaw RJ,Palmer L,Blasey C,Sarwal M

更新日期：2003-12-01 00:00:00

abstract：:ADV is frequently seen in our pediatric SOT population. It presents in a variety of clinical presentation and can cause severe disease. In this population, there are very few studies to determine the safety of CDV as a potential therapeutic agent. We present the findings of our retrospective study evaluating the effic...

journal_title：Pediatric transplantation

authors： Guerra Sanchez CH,Lorica CD,Arheart KL,Perez MM,Tekin A,Gonzalez IA

更新日期：2018-06-03 00:00:00

abstract：:Recurrent FSGS is a major challenge in the field of nephrology. To clarify the role of NPHS2 defects in the pathogenesis of FSGS recurrence, we sequenced all eight exons of NPHS2 in 11 Japanese pediatric FSGS patients with or without post-transplant recurrence. All patients had biopsy-proven primary FSGS, had no famil...

journal_title：Pediatric transplantation

authors： Furue T,Hattori M,Tsukaguchi H,Kitamura A,Oomori T,Ogino D,Nakakura H,Ashida A,Miura K,Hisano M,Takahashi K,Chikamoto H,Akioka Y,Sakano T

更新日期：2008-05-01 00:00:00

abstract：:SAB assays have increased the sensitivity and specificity to detect HLA alloantibodies, but there is uncertainty about the clinical relevance of SAB-positive alloantibodies when the FCXM is negative. We performed a retrospective study to evaluate the clinical significance of SAB-detected DSA in 82 pediatric recipients...

journal_title：Pediatric transplantation

authors： Verghese PS,Smith JM,McDonald RA,Schwartz SM,Nelson KA,Warner PR

更新日期：2010-09-01 00:00:00

abstract：:The aim of this study was to re-evaluate the indications and timing of LT for WD. From 2000 to 2009, eight patients with WD who had been referred to our institution for LT were enrolled in this study. The mean patient age was 15.9 yr (range, 7-37 yr). Four patients could not receive LT, because there were no available...

journal_title：Pediatric transplantation

authors： Ohya Y,Okajima H,Honda M,Hayashida S,Suda H,Matsumoto S,Lee KJ,Yamamoto H,Takeichi T,Mitsubuchi H,Asonuma K,Endo F,Inomata Y

更新日期：2013-06-01 00:00:00

abstract：:Abdominal closure in children less than 10 kg following liver or kidney transplantation can be challenging. Excessive pressure attained from a tight closure can result in abdominal compartment syndrome, graft compromise and loss. Concerns over using prosthetic patches are that of infection and dehiscence. We report a ...

journal_title：Pediatric transplantation

authors： Karpelowsky JS,Thomas G,Shun A

更新日期：2009-05-01 00:00:00

abstract：:To evaluate the effects of gender on HRQOL and overall health status in our pediatric kidney transplants. We performed a cross-sectional study in 77 children who received living renal allo-transplants in our center between 1981 and 2003. The patients were given a questionnaire at a post-transplant visit. After complet...

journal_title：Pediatric transplantation

authors： El-Husseini A,Hassan R,Sobh M,Ghoneim M

更新日期：2010-03-01 00:00:00

abstract：:Cardiac transplantation for children with end-stage cardiac disease with no other medical or surgical options is now standard. The number of children in need of cardiac transplant continues to exceed the number of donors considered "acceptable." Therefore, there is an urgent need to understand which recipients are in ...

journal_title：Pediatric transplantation

authors： Denfield SW,Azeka E,Das B,Garcia-Guereta L,Irving C,Kemna M,Reinhardt Z,Thul J,Dipchand AI,Kirk R,Davies RR,Miera O

更新日期：2020-05-01 00:00:00

abstract：:This review details the indications for heart transplantation in children. Contraindications have evolved from absolute to relative. Controversial issues remain and this paper represents a consensus of more than a dozen centers that have programs that remain active performing pediatric heart transplants. ...

journal_title：Pediatric transplantation

authors： Fricker FJ,Addonizio L,Bernstein D,Boucek M,Boucek R,Canter C,Chinnock R,Chin C,Kichuk M,Lamour J,Pietra B,Morrow R,Rotundo K,Shaddy R,Schuette EP,Schowengerdt KO,Sondheimer H,Webber S

更新日期：1999-11-01 00:00:00

abstract：:The risk of adverse outcomes for pediatric renal transplant patients is highest during the transition from pediatric to adult care. While there have been many studies focus on graft failure and death, loss to follow-up likely plays a large role in patient outcomes. We hypothesize patients are lost to follow-up during ...

journal_title：Pediatric transplantation

authors： Hung YC,Williams JE,Bababekov YJ,Rickert CG,Chang DC,Yeh H

更新日期：2019-11-01 00:00:00

abstract：:This study reports the clinical complication and infection rates of an active pediatric IT program that has never utilized bowel decontamination in either the donor or the recipient. All patients undergoing IT from 2003 to 2015 at a single pediatric IT center were reviewed. Post-transplant surgical, infectious, and im...

journal_title：Pediatric transplantation

authors： Clouse JW,Kubal CA,Fridell JA,Mangus RS

更新日期：2018-05-01 00:00:00

abstract：:Injuries sustained by major vessels during procurement pose a major threat to organ viability. Aortic and inferior vena cava lacerations produce rapid hemorrhage associated with hypoperfusion and ischemic damage. We describe a technique that will prevent such damage in the event of vascular mishaps. ...

journal_title：Pediatric transplantation

authors： Molmenti EP,Molmenti H,Marubashi S,Sanchez EQ,Gogel B,Goldstein RM,Levy MF,Fasola CG,Gonwa TA,Klintmalm GB

更新日期：2001-10-01 00:00:00

abstract：:Antibody-mediated rejection (AMR) has recently been recognized as a significant and unique form of rejection that is not amenable to treatment with standard immunosuppressive medications aimed at modification of T-cell function. Recent interest in AMR and the role of B cells in rejection has been aided by the concomit...

journal_title：Pediatric transplantation

authors： Jordan SC,Vo AA,Tyan D,Nast CC,Toyoda M

更新日期：2005-06-01 00:00:00

abstract：:In patients with myocytolysis detected in endomyocardial biopsy, there is a tendency towards a shift of ventricular electrical axes from normal to strain pattern on surface ECG. Their 12-lead signal-averaged electrocardiogram (SAECG) show a significant increase in filtered QRS duration (QRSD) compared with those with ...

journal_title：Pediatric transplantation

authors： Bennhagen RG,Sörnmo L,Pahlm O,Pesonen E

更新日期：2005-12-01 00:00:00

abstract：:Rejection remains a major threat in pediatric renal transplantation (Tx), causing graft failure and increased exposure to drugs. The new chimeric antibody, basiliximab, directed against the alpha-chain of the interleukin-2 receptor (IL-2R), has been shown to be effective in preventing rejection episodes in adult renal...

journal_title：Pediatric transplantation

authors： Vester U,Kranz B,Testa G,Malagò M,Beelen D,Broelsch CE,Hoyer PF

更新日期：2001-08-01 00:00:00

abstract：:The role of unrelated donor HSCT for children with de novo AML in CR1 is controversial. We performed this study to investigate the feasibility of unrelated donor HSCT who initially had intermediate- or high-risk cytogenetics. We retrospectively reviewed medical records of patients with AML who received unrelated HSCT ...

journal_title：Pediatric transplantation

authors： Park EG,Yi ES,Choi YB,Sung KW,Koo HH,Yoo KH

更新日期：2019-06-01 00:00:00

abstract：:With the increasing adoption of steroid-sparing immunosuppression protocols in renal transplantation, it is important to evaluate any adverse effects of steroid avoidance on graft function. Early graft function, measured by CrCl was retrospectively studied in 158 consecutive pediatric renal transplant recipients from ...

journal_title：Pediatric transplantation

authors： Li L,Weintraub L,Concepcion W,Martin JP,Miller K,Salvatierra O,Sarwal MM

更新日期：2008-09-01 00:00:00

abstract：:BM remains an important source of stem cells. The BM characteristics change with age but the estimation of CD34 calculation of one CD34+ cell per 100 nucleated cells is used for all donors including pediatric donors in the operating room before getting the actual CD34 count. In order to see whether this formula is app...

journal_title：Pediatric transplantation

authors： Ince EU,Ileri T,Dogu F,Ates C,Cakmakli H,Dalva K,Ikinciogullari A,Uysal Z,Ertem M

更新日期：2015-06-01 00:00:00