Effect of CYP3A5*1 expression on tacrolimus required dose for transplant pediatrics: A systematic review and meta-analysis.

abstract：:The clinical significance of parvovirus B19 infection in pediatric solid-organ and bone marrow transplanted patients is unclear. The overall prevalence of parvovirus B19 infection in these patients is about 1-2% during the first year after transplantation. The most common symptom is anemia, but leukopenia and thromboc...

journal_title：Pediatric transplantation

authors： Broliden K

更新日期：2001-10-01 00:00:00

abstract：:A generic version of tacrolimus was approved for use in the USA in August 2009. These narrow therapeutic index generics are tested for bioequivalence only in adults. No data are available on generic tacrolimus levels in children with allografts. Four patients with stable renal allografts in our pediatric program were ...

journal_title：Pediatric transplantation

authors： Abdulnour HA,Araya CE,Dharnidharka VR

更新日期：2010-12-01 00:00:00

abstract：:Graft-vs-host disease (GVHD) is one of the most difficult problems in stem cell transplantation. It is best considered in the context of the normal immune response. The role of the immune system is to identify and eliminate foreign antigens. In the case of GVHD, the antigens are minor histocompatibility antigens (mHA)...

journal_title：Pediatric transplantation

authors： Antin JH

更新日期：2005-12-01 00:00:00

abstract：:The thymus gland possesses the ability to regrow in children leading to a newly developed anterior mediastinal mass. This condition may represent a rebound phenomenon during recovery from a stressful event such as post-chemotherapy and hence was described as RTH. RTH after LT has not been well documented. We are repor...

journal_title：Pediatric transplantation

authors： Wang TK,Kuo FY,Lee SY,Cheng YF,Elsarawy AM,Lin CC,Lin TL,Chen CL

更新日期：2018-07-24 00:00:00

abstract：:Vascular complications remain the most common cause of early renal allograft loss in patients with end-stage renal failure. Underlying thrombophilic disorders increase the risk of early graft thrombosis. A male adolescent with high-risk thrombophilia because of combined heterozygous factor V Leiden (G1691A) and prothr...

journal_title：Pediatric transplantation

authors： John U,Kentouche K,Nowak G,Schubert J,Misselwitz J

更新日期：2006-02-01 00:00:00

abstract：:Since the discovery of hepatitis C virus (HCV) in 1989, significant advances have been made in our understanding of this important viral pathogen. Children at risk for HCV infection include recipients of potentially contaminated blood products and organ transplants, and infants born to HCV-infected mothers. Chronic HC...

journal_title：Pediatric transplantation

authors： González-Peralta RP

更新日期：2004-12-01 00:00:00

abstract：:INFVA is an important cause of pulmonary infections in patients receiving BMT, and is associated with considerable morbidity and mortality for a readily preventable and treatable infection. Few studies have addressed the impact of the new neuraminidase inhibitors in the prognosis of influenza after BMT. The aim of thi...

journal_title：Pediatric transplantation

authors： Mellouli F,Ouederni M,Dhouib N,Hajkacem MA,Slim A,Bejaoui M

更新日期：2010-03-01 00:00:00

abstract：:Data from 997 pediatric LT recipients were used to model demographic and medical variables as predictors of lower levels of HRQOL. Data were collected through SPLIT FOG project. Patients were between 2 and 18 yr of age and survived LT by at least 12 months. Parents and children (age ≥ 8 yr) completed PedsQL™ 4.0 Gener...

journal_title：Pediatric transplantation

authors： Alonso EM,Martz K,Wang D,Yi MS,Neighbors K,Varni JW,Bucuvalas JC,Studies of Pediatric Liver Transplantation (SPLIT) Functional Outcomes Group (FOG).

更新日期：2013-11-01 00:00:00

abstract：:Thrombosis after kidney transplantation may result in catastrophic outcomes, including graft loss. Thrombophilia has been implicated in post-transplant thrombosis; data, however, are inconclusive on the impact of acquired and inherited thrombophilia and resultant thrombosis in renal graft recipients. We aimed to evalu...

journal_title：Pediatric transplantation

authors： Bock ME,Bobrowski AE,Bhat R

更新日期：2019-02-01 00:00:00

abstract：:PTLD is a major complication after transplantation. Treatment options for PTLD are not standardized, usually sequential, starting with reduction in immunosuppression. Recently, we have used a dual combination of rituximab and reduced dose chemotherapy (R/C) directly after failed RI. We retrospectively identified 30 pe...

journal_title：Pediatric transplantation

authors： Gupta S,Fricker FJ,González-Peralta RP,Slayton WB,Schuler PM,Dharnidharka VR

更新日期：2010-11-01 00:00:00

abstract：:Renal transplantation is the treatment of choice for children with ESRD offering advantages of improved survival, growth potential, cognitive development, and quality of life. The aim of our study was to compare the outcomes of LDKT vs DDKT performed in children at a single center. Retrospective chart review of pediat...

journal_title：Pediatric transplantation

authors： Pérez-Bertólez S,Barrero R,Fijo J,Alonso V,Ojha D,Fernández-Hurtado MÁ,Martínez J,León E,García-Merino F

更新日期：2017-05-01 00:00:00

abstract：:Liver and small bowel transplant is an established treatment for infants with IFALD. Despite organ reduction techniques, mortality on the waiting list remains high due to shortage of size-matched pediatric donors. Small abdominal cavity volume due to previous intestinal resection poses a significant challenge to achie...

journal_title：Pediatric transplantation

authors： Vidyadharan R,van Bommel AC,Kuti K,Gupte GL,Sharif K,Richard BM

更新日期：2013-11-01 00:00:00

abstract：:We sought to examine the relationship between liver transplant-related total cost, patient outcome, and hospital resource utilization at freestanding children's hospitals. Using the PHIS database, a retrospective study of 374 patients that underwent liver transplantation at 15 freestanding children's hospitals from Ju...

journal_title：Pediatric transplantation

authors： Minneman JA,Grijalva JL,LaQuaglia MJ,Kim HB,Rangel SJ,Vakili K

更新日期：2016-11-01 00:00:00

abstract：:During the past 50 yr, intensive studies into the use of hematopoietic cell transplantation (HCT) for therapy of cancer and non-malignant hematologic diseases have changed this treatment modality from one that was thought to be plagued by insurmountable complications to one that is now standard therapy for some diseas...

journal_title：Pediatric transplantation

authors： Storb R

更新日期：2004-06-01 00:00:00

abstract：:eHAT is one of the most dreaded post-LT complication. Treatment approaches include retransplantation, revascularization, or observation. Systemic thrombolytic therapy is used in pediatric patients with thromboembolic events. However, there is no previous study reporting on the use of systemic r-tPA to treat eHAT. The ...

journal_title：Pediatric transplantation

authors： Feier FH,Melere MU,Trein CS,da Silva CS,Lucchese A,Horbe A,Tonet F,Ricachinevsky C,Ferreira CT,Chedid MF,Kalil AN

更新日期：2020-10-27 00:00:00

abstract：UNLABELLED:OLT is a life-saving option for ALF. AIM:To evaluate our outcomes in pediatric OLT for ALF. METHODS:Retrospective review of our data between 1992 and 2007. RESULTS:Of 142 children with ALF, 126 were listed, of which 40 spontaneously improved, nine died, and 77 underwent OLT (median waiting time four days)...

journal_title：Pediatric transplantation

authors： Miloh T,Kerkar N,Parkar S,Emre S,Annunziato R,Mendez C,Arnon R,Suchy F,Rodriguez-Laiz G,Del Rio Martin J,Sturdevant M,Iyer K

更新日期：2010-11-01 00:00:00

abstract：:Cryptosporidium is an intracellular protozoa that can cause gastroenteritis in humans. In immunocompromised hosts, infection can be severe, leading to life-threatening persistent diarrhea. There is limited experience in treating this infection in solid organ transplants. Although newer drugs active against Cryptospori...

journal_title：Pediatric transplantation

authors： Hong DK,Wong CJ,Gutierrez K

更新日期：2007-02-01 00:00:00

abstract：:PPCA has historically been considered detrimental to donor quality in LT, but transplantation of grafts from this group of donors is now routine. Our study aims to evaluate the outcomes associated with use of donors with a history of PPCA in the pediatric population. This study is a single-center retrospective analysi...

journal_title：Pediatric transplantation

authors： Schroering JR,Hathaway TJ,Kubal CA,Ekser B,Mihaylov P,Mangus RS

更新日期：2020-08-01 00:00:00

abstract：:CHD is the most commonly occurring birth defect in the United States. Improvements in supportive care for CHD result in increasing numbers of survivors who may develop benign or malignant conditions for which HSCT is indicated. However, the ability of individuals with CHD to tolerate HSCT is unknown. Retrospective med...

journal_title：Pediatric transplantation

authors： Guinan EC,Hewett EK,Domaney NM,Margossian R

更新日期：2011-02-01 00:00:00

abstract：:Bacillus cereus is a spore-forming, gram-positive bacterium that causes food poisoning presenting with either emesis or diarrhea. Diarrhea is caused by proteinaceous enterotoxin complexes, mainly hemolysin BL, non-hemolytic enterotoxin (NHE), and cytotoxin K. In contrast, emesis is caused by the ingestion of the depsi...

journal_title：Pediatric transplantation

authors： Tschiedel E,Rath PM,Steinmann J,Becker H,Dietrich R,Paul A,Felderhoff-Müser U,Dohna-Schwake C

更新日期：2015-02-01 00:00:00

abstract：:  We present an 18-yr-old adolescent with acute lymphocytic leukemia, who underwent peripheral blood SCT with serologically and histologically documented chronic hepatitis B infection. Prior and during the transplant process, lamivudine was administered orally and he underwent SCT with a twofold decrease in viral load...

journal_title：Pediatric transplantation

authors： Serap A,Funda O,Bengu K,Mehmet K,Nazan C,Rasit Y,Savas K

更新日期：2011-08-01 00:00:00

abstract：:Malnutrition adversely affects mortality and morbidity before and after liver transplantation. Outcome might be improved if liver transplant recipients were in a better nutritional state at the time of transplantation. In this review, we will examine the potential use of GH and IGF-I to improve nutritional status in p...

journal_title：Pediatric transplantation

authors： Bucuvalas JC,Horn JA,Chernausek SD

更新日期：1997-08-01 00:00:00

abstract：:ABO-ILT have re-emerged as an alternate option for select patients awaiting transplant. However, treatment protocols for children undergoing deceased donor ABO-ILT are not standardized. We implemented a novel IS protocol for children undergoing deceased donor ABO-ILT based on pretransplant IH titers. Children with hig...

journal_title：Pediatric transplantation

authors： Mysore KR,Himes RW,Rana A,Teruya J,Desai MS,Srivaths PR,Zaruca K,Calvert A,Guffey D,Minard CG,Morita E,Hensch L,Losos M,Kostousov V,Hui SR,Orange JS,Goss JA,Nicholas SK

更新日期：2018-11-01 00:00:00

abstract：:Organ transplants between genetically different individuals elicit powerful immune responses that invariably cause rejection in the absence of immune suppression. Among the immune responses elicited by organ allografts, B-cell responses causing antibody-mediated rejection are one of the most vexing. However, recent ad...

journal_title：Pediatric transplantation

authors： Balin SJ,Platt JL,Cascalho M

更新日期：2008-08-01 00:00:00

abstract：:We report a case of arterio-portal fistulae in a 12-month-old-child following a segmental liver transplantation. The fistula, probably the result of mass ligature of a vascular pedicle during back table allograft reduction, is to our knowledge the first such case reported. Diagnosed on the third post-operative day, th...

journal_title：Pediatric transplantation

authors： Mieles LA,Waldman D,Orloff MS

更新日期：2002-10-01 00:00:00

abstract：:The risk of adverse outcomes for pediatric renal transplant patients is highest during the transition from pediatric to adult care. While there have been many studies focus on graft failure and death, loss to follow-up likely plays a large role in patient outcomes. We hypothesize patients are lost to follow-up during ...

journal_title：Pediatric transplantation

authors： Hung YC,Williams JE,Bababekov YJ,Rickert CG,Chang DC,Yeh H

更新日期：2019-11-01 00:00:00

abstract：:CVD is a major cause of morbidity and mortality in pediatric patients with CKD. It is unclear whether vascular abnormalities in these patients are reversible, and if transplantation portends salutary effects on arterial function. We compared FMD, PWV, AI75, and CIMT in 15 dialysis (D), 14 transplant patients (T), and ...

journal_title：Pediatric transplantation

authors： Tawadrous H,Kamran H,Salciccioli L,Schoeneman MJ,Lazar J

更新日期：2012-08-01 00:00:00

abstract：:Nonalcoholic steatohepatitis (NASH) is the most severe form of non-alcoholic fatty liver disease (NAFLD). The aim of our study was to highlight NASH as a rare but possible problem in children. We present a case of 13-yr-boy with a well-established diagnosis of liver cirrhosis secondary to NASH, who underwent orthotopi...

journal_title：Pediatric transplantation

authors： Jankowska I,Socha P,Pawlowska J,Teisseyre M,Gliwicz D,Czubkowski P,Kalicinski P,Cielecka-Kuszyk J,Socha J

更新日期：2007-11-01 00:00:00

abstract：:Biliary atresia is defined as partial or total obliteration of the extra-hepatic bile ducts. In advanced cases, liver transplantation (LTx) is considered the most appropriate treatment. This report describes a female patient whose biliary atresia and subsequent cirrhosis required LTx at 1 yr of age. Macroscopic inspec...

journal_title：Pediatric transplantation

authors： Bilezikçi B,Demirhan B,Kiyici H,Haberal M

更新日期：2001-02-01 00:00:00

abstract：:We reviewed 112 pediatric renal transplant recipients to document the rate of medication non-adherence (NA) and to examine the relationships between NA, comorbid psychiatric illness, and the outcome variables of acute and chronic rejection and graft loss. A total of 32.5% of subjects had clinically significant NA with...

journal_title：Pediatric transplantation

authors： Shaw RJ,Palmer L,Blasey C,Sarwal M

更新日期：2003-12-01 00:00:00