Approaches to graft-vs-host disease.

abstract：:Recipient lymphocytes are crucial for direct and indirect pathways of allorecognition. We proposed that the administration of alemtuzumab several weeks pretransplantation could eradicate peripheral lymphatic cells and promote donor-specific acceptance. This was a single-center, retrospective review of 101 consecutive ...

journal_title：Pediatric transplantation

authors： Kaabak MM,Babenko NN,Shapiro R,Maschan AA,Zokoev AK,Schekaturov SV,Vyunkova JN,Dymova OV

更新日期：2017-08-01 00:00:00

abstract：:An increasing number of individuals with end-stage renal disease have become sensitized to human leukocyte antigens (HLA). Sensitization can have a profound impact on the likelihood of obtaining a requisite negative crossmatch (-XM) with a potential donor. Technologic breakthroughs in our ability to diagnose antibody-...

journal_title：Pediatric transplantation

authors： Montgomery RA,Zachary AA

更新日期：2004-12-01 00:00:00

abstract：:There is a limited supply of organs for all those who need them for survival. Thus, careful decisions must be made about who is listed for transplant. Studies show that manifesting genetic disease can impact listing eligibility. What has not yet been studied is the impact genetic risks for future disease have on a pat...

journal_title：Pediatric transplantation

authors： Graf M,Char D,Hanson-Kahn A,Magnus D

更新日期：2019-06-01 00:00:00

abstract：:Pediatric cardiac transplant has become increasingly frequent in the last decade and survival rates have improved remarkably. Outcome research on this population suggests that the majority of children have the capacity for healthy adaptation although 25-40% have been shown to have some type of psychiatric difficulties...

journal_title：Pediatric transplantation

authors： Weil CM,Rodgers S,Rubovits S

更新日期：2006-12-01 00:00:00

abstract：:MCs are important effector cells in a broad range of immune responses. Their role in liver allograft rejection is not clear. Twenty-one liver transplant recipients (mean age +/- s.d.; 10.2 +/- 4.1 yr) who experienced a rejection episode are included in this study. Biopsy specimens from normal livers (allograft biopsy ...

journal_title：Pediatric transplantation

authors： Arikan C,Nart D,Kilic M,Yuksekkaya HA,Aydogdu S

更新日期：2008-05-01 00:00:00

abstract：:Cardiac transplantation for children with end-stage cardiac disease with no other medical or surgical options is now standard. The number of children in need of cardiac transplant continues to exceed the number of donors considered "acceptable." Therefore, there is an urgent need to understand which recipients are in ...

journal_title：Pediatric transplantation

authors： Denfield SW,Azeka E,Das B,Garcia-Guereta L,Irving C,Kemna M,Reinhardt Z,Thul J,Dipchand AI,Kirk R,Davies RR,Miera O

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND/AIM:Several PK studies have shown that most pediatric patients may require higher doses on a mg/kg basis compared to adults to attain similar therapeutic trough concentrations. The aim of this study was to compare the efficacy and safety of three times daily to twice a day dosing of tacrolimus in pediatric k...

journal_title：Pediatric transplantation

authors： Alabdulkarim Z,Al-Jedai A,Alkortas D,Alhasan K,Devol E

更新日期：2020-09-01 00:00:00

abstract：:Rural status of patients may impact health before and after pediatric LT. We used UI codes published by the USDA to stratify patients as urban or rural depending county residence. A total of 388 patients who had LT and who met criteria were included. Rejection, PTLD, and survival were used as primary outcome measures ...

journal_title：Pediatric transplantation

authors： Park KT,Nanda P,Bensen R,Strichartz D,Esquivel C,Cox K

更新日期：2011-05-01 00:00:00

abstract：:Anelloviruses are DNA viruses ubiquitously present in human blood. Due to their elevated levels in immunosuppressed patients, anellovirus levels have been proposed as a marker of immune status. We hypothesized that low anellovirus levels, reflecting relative immunocompetence, would be associated with adverse outcomes ...

journal_title：Pediatric transplantation

authors： Blatter JA,Sweet SC,Conrad C,Danziger-Isakov LA,Faro A,Goldfarb SB,Hayes D Jr,Melicoff E,Schecter M,Storch G,Visner GA,Williams NM,Wang D

更新日期：2018-02-01 00:00:00

abstract：:Children who undergo heart transplantation are at risk for long-term neurodevelopmental sequelae secondary to heart disease and its treatment. Detailed neuropsychological profiles in clinical sample status post-pediatric heart transplantation are sparse in the literature, and there is little information regarding pred...

journal_title：Pediatric transplantation

authors： Wolfe KR,Kelly SL,Steinberg E,Pliego J,Everitt MD

更新日期：2020-02-01 00:00:00

abstract：:Despite significant interest by pediatric transplant patients in meeting others who have undergone transplantation, geographic distances combined with their daily routines make this difficult. This mixed-method study describes the use of Zora, a Web-based virtual community designed to create a support system for these...

journal_title：Pediatric transplantation

authors： Bers MU,Beals LM,Chau C,Satoh K,Blume ED,DeMaso DR,Gonzalez-Heydrich J

更新日期：2010-03-01 00:00:00

abstract：:Delayed recovery of thrombocytopenia is a well-known complication after allogeneic HSCT. Eltrombopag (ELT), a thrombopoietin receptor agonist (TRAs), induces platelet maturation and release. Mostly conducted in adults, some of the previous studies have shown that ELT seems to enhance platelet recovery for post-allogen...

journal_title：Pediatric transplantation

authors： Yaman Y,Elli M,Şahin Ş,Özdilli K,Bilgen H,Bayram N,Nepesov S,Anak S

更新日期：2021-01-16 00:00:00

abstract：:Epstein-Barr virus (EBV)-associated post-transplant lymphoproliferative disease (PTLD) is a serious complication of organ and bone marrow transplantation. The importance of EBV matching between recipient and donor remains unclear. Between October 1987 and December 1997, 64 pediatric cardio-pulmonary transplants were p...

journal_title：Pediatric transplantation

authors： Harwood JS,Gould FK,McMaster A,Hamilton JR,Corris PA,Hasan A,Gennery AR,Dark JH

更新日期：1999-05-01 00:00:00

abstract：:Immunosuppression regimens after liver transplantation focus mainly on preventing rejection and subsequent graft loss. However, in children, morbidity and mortality rates from infections exceed those from rejection after transplant, and immunosuppression can hinder growth, renal function, and graft tolerance. We hypot...

journal_title：Pediatric transplantation

authors： Turmelle YP,Nadler ML,Anderson CD,Doyle MB,Lowell JA,Shepherd RW

更新日期：2009-08-01 00:00:00

abstract：:DIDS is a unique form of combined immune deficiency characterized by an unusual susceptibility to cutaneous viral infections, severe allergies with eosinophilia and elevated immunoglobulin E titers, autoimmunity, and cancer. HSCT is considered the standard of care for this deadly disease. We have retrospectively analy...

journal_title：Pediatric transplantation

authors： Uygun DFK,Uygun V,Reisli İ,Keleş S,Özen A,Yılmaz M,Sayar EH,Daloğlu H,Öztürkmen SI,Çakı S,Karasu GT,Yeşilipek A

更新日期：2017-11-01 00:00:00

abstract：:HSCT-associated thrombotic microangiopathy (TA-TMA) is a severe complication with a poor prognosis. Recently, it has been reported that complement system dysregulation, such as CFH autoantibodies and deletions CFH-related genes 3 and 1, induced TA-TMA. In addition, C4d-positive renal arterioles are both a good marker ...

journal_title：Pediatric transplantation

authors： Sakamoto K,Imamura T,Osone S,Nishimura A,Nishida M,Ishida H,Hosoi H

更新日期：2015-06-01 00:00:00

abstract：:To evaluate the role of BAL, CTB, and OLB in the management of pulmonary infiltrates in pediatric HSCT recipients, we conducted a retrospective review of clinical records of pediatric HSCT recipients. Data were analyzed using Chi-square for dichotomous and anova for continuous variables. Logistic regression was used t...

journal_title：Pediatric transplantation

authors： Armenian SH,Hoffman JA,Butturini AM,Kapoor N,Mascarenhas L

更新日期：2007-11-01 00:00:00

abstract：:I was asked to write this article to share with medical professionals, my view as a parent with a child who has special needs and needs a transplant. It is a detailed story from a parent's point of view on what it is like to have a child with special needs with serious medical complications and how I went about findin...

journal_title：Pediatric transplantation

authors： Carney MT

更新日期：2021-02-01 00:00:00

abstract：:To evaluate whether a serial biliary dilation protocol improves outcomes and decreases total biliary drainage time for biliary strictures following pediatric liver transplantation. From 2006 to 2016, 213 orthotopic deceased and living related liver transplants were performed in 199 patients with a median patient age o...

journal_title：Pediatric transplantation

authors： Reis SP,Bruestle K,Brejt S,Tulin-Silver S,Frenkel J,Mobley DG,England RW,Sobolevsky S,Griesemer AD,Sperling D,Schlossberg P,Susman J,Weintraub JL

更新日期：2019-11-01 00:00:00

abstract：:Hepatic veno-occlusive disease (VOD) after stem cell transplantation is a toxic manifestation of the conditioning regimen most probably emphasized by the allogeneic reaction. Its overall mortality rate is < 4% in adults as well as in children. Recent progress has been achieved in the diagnosis of this complication. Ho...

journal_title：Pediatric transplantation

authors： Ribaud P,Gluckman E

更新日期：1999-01-01 00:00:00

abstract：:There is a shortage of pediatric donor hearts for waitlisted children, and yet nearly 50% of organs offered are not transplanted. Donor quality is often cited as a reason for declining organs offered from donors infected with influenza, presumably due to concern about disease transmission at transplant leading to seve...

journal_title：Pediatric transplantation

authors： Smith CJ,McCulloch MD,Shirley DA,L'Ecuyer TJ

更新日期：2019-12-01 00:00:00

abstract：:Myocarditis represents an important cause for acute heart failure. MYKKE, a prospective multicenter registry of pediatric patients with myocarditis, aims to gain knowledge on courses, diagnostics, and therapy of pediatric myocarditis. The role of mechanical circulatory support (MCS) in children with severe heart failu...

journal_title：Pediatric transplantation

authors： Schubert S,Opgen-Rhein B,Boehne M,Weigelt A,Wagner R,Müller G,Rentzsch A,Zu Knyphausen E,Fischer M,Papakostas K,Wiegand G,Ruf B,Hannes T,Reineker K,Kiski D,Khalil M,Steinmetz M,Fischer G,Pickardt T,Klingel K,Messr

更新日期：2019-11-01 00:00:00

abstract：:Thrombosis after kidney transplantation may result in catastrophic outcomes, including graft loss. Thrombophilia has been implicated in post-transplant thrombosis; data, however, are inconclusive on the impact of acquired and inherited thrombophilia and resultant thrombosis in renal graft recipients. We aimed to evalu...

journal_title：Pediatric transplantation

authors： Bock ME,Bobrowski AE,Bhat R

更新日期：2019-02-01 00:00:00

abstract：:The availability of new and more effective anti-rejection therapy has succeeded in reducing the incidence of acute cellular rejection in first months post-renal transplant. This in turn has escalated the order of significance of recurrence of primary disease in the renal allograft as a cause for patient morbidity and ...

journal_title：Pediatric transplantation

authors： Seikaly MG

更新日期：2004-04-01 00:00:00

abstract：:Despite the fact that non-adherence to medical therapy is one of the major causes of late morbidity and mortality in pediatric liver transplant recipients, little is known of the risk factors involved in this behavior. Three cases of fatal non-adherence are reported. Factors associated with non-adherence were investig...

journal_title：Pediatric transplantation

authors： Lurie S,Shemesh E,Sheiner PA,Emre S,Tindle HL,Melchionna L,Shneider BL

更新日期：2000-08-01 00:00:00

abstract：:Paediatric HR T-cell ALL demonstrates dismal prognosis with chemotherapy, and poor outcomes could be improved with allo-SCT. HID-SCT is an almost immediately available choice; however, few studies have focused on the outcomes of HID-SCT for paediatric HR T-ALL. Forty-eight consecutive HR T-ALL children who underwent H...

journal_title：Pediatric transplantation

authors： Xu ZL,Huang XJ,Liu KY,Chen H,Zhang XH,Han W,Chen YH,Wang FR,Wang JZ,Wang Y,Chen Y,Yan CH,Xu LP

更新日期：2016-06-01 00:00:00

abstract：:BWS is one of the most well-known somatic overgrowth syndromes, which is characterized by macroglossia, organomegaly, abdominal wall defects, and predisposition to embryonal tumors, such as Wilms' tumor, hepatoblastoma, and adrenocortical carcinoma. We report a case of BWS in a girl with unresectable hepatoblastoma, w...

journal_title：Pediatric transplantation

authors： Sasaki K,Kasahara M,Fukuda A,Shigeta T,Tanaka H,Nakagawa S,Mitsui K,Harada R,Nakagawa A

更新日期：2010-11-01 00:00:00

abstract：:The prospective cross-sectional study investigated the 6MWT performance in pediatric group of liver transplant recipients (6-17 yr, median post-transplantation time of 22 months) and compared to the normal values obtained in healthy children as well as evaluated the reproducibility of the 6MWT. We analyzed the relatio...

journal_title：Pediatric transplantation

authors： Maria da Silva R,Brunow de Carvalho W,Johnston C,Borba de Castro M,Manta Ferreira I,Patti CL,Anthero de Azevedo R,Miziara Gonzalez A,Moura Linhares M,Augusto Salzedas-Netto A

更新日期：2014-09-01 00:00:00

abstract：:Parents of pediatric liver and kidney transplant recipients were surveyed regarding their current education plans (eg, Individualized Education Program, 504), satisfaction with these plans, and interest in educational support from the psychosocial transplant team. Survey results indicate high rates of IEP and 504 plan...

journal_title：Pediatric transplantation

authors： daCruz K,Cousino MK,Smith T,Bilhartz J,Eder SJ,Fredericks EM

更新日期：2019-06-01 00:00:00

abstract：:We report the occurrence of epididymitis and orchitis 1 week after the onset of Listeriosis in an 11-month-old boy receiving an orthotopic liver transplantation for biliary atresia. Immunologic implications of Listeria monocytogenes-induced testicular inflammation are discussed, and the potential role of immunosuppres...

journal_title：Pediatric transplantation

authors： von Schnakenburg C,Hinrichs B,Fuchs J,Kardorff R

更新日期：2000-05-01 00:00:00