Towards minimizing immunosuppression in pediatric liver transplant recipients.

abstract：:Laparoscopic donor nephrectomy (LDN) is rapidly becoming the preferred technique for the procurement of living donor kidneys. An association of this technique with delayed graft function and higher risk for rejection has been reported in pediatric recipients. We reviewed our experience of 17 pediatric patients who rec...

journal_title：Pediatric transplantation

authors： Baqi N,Stock J,Lombardo SA,Geffner S,Roberti I

更新日期：2006-05-01 00:00:00

abstract：:Patients with defects in the ATP6AP1 gene have rarely been described. ATP6AP1-related disorders are a subtype of CDG, which result in enzyme deficiencies affecting multiple organ systems ranging from mild to life-threatening. Of the 13 patients described, all had hepatopathy, but this is the first case to be successfu...

journal_title：Pediatric transplantation

authors： Gumm AJ,Basel DG,Thakrar P,Suchi M,Telega G

更新日期：2020-12-01 00:00:00

abstract：:Hypogammaglobulinemia is common after pediatric SCT and IgG replacement is recommended. Some children will have a prolonged hypogammaglobulinemia but may have poor venous access which impedes further iv IgG replacement. In primary antibody deficiencies, sc IgG replacement, performed by parents at home, has been shown ...

journal_title：Pediatric transplantation

authors： Sundin M,Nordin K,Jostemyr Y,Winiarski J

更新日期：2012-12-01 00:00:00

abstract：:aHUS is caused by the over-activation and dysregulation of the alternative complement pathway. Data regarding outcomes of pediatric aHUS patients after kidney transplantation are still very scarce. Accordingly, the aim of this study was to describe the clinical findings and outcomes of pediatric aHUS patients after re...

journal_title：Pediatric transplantation

authors： Özçakar ZB,Ozaltin F,Gülhan B,Çomak E,Parmaksız G,Baskın E,Topaloğlu R,Kasap Demir B,Canpolat N,Yuruk Yildirim Z,Demircioğlu Kılıç B,Yüksel S,Söylemezoğlu O

更新日期：2020-11-20 00:00:00

abstract：:Recipient lymphocytes are crucial for direct and indirect pathways of allorecognition. We proposed that the administration of alemtuzumab several weeks pretransplantation could eradicate peripheral lymphatic cells and promote donor-specific acceptance. This was a single-center, retrospective review of 101 consecutive ...

journal_title：Pediatric transplantation

authors： Kaabak MM,Babenko NN,Shapiro R,Maschan AA,Zokoev AK,Schekaturov SV,Vyunkova JN,Dymova OV

更新日期：2017-08-01 00:00:00

abstract：:Mycoplasma pneumoniae has rarely been reported in renal transplant recipients. We present the case of a 10-yr-old boy with a six-month history of chronic cough, recurrent pyrexia, and weight loss three yr after RTx. The patient's post-transplant course was complicated by recurrence of NS that resolved with plasmaphere...

journal_title：Pediatric transplantation

authors： Schwerk N,Hartmann C,Baumann U,Pape L,Ehrich JH,Hansen G

更新日期：2010-05-01 00:00:00

abstract：:Renal transplantation is the treatment of choice for children with ESRD offering advantages of improved survival, growth potential, cognitive development, and quality of life. The aim of our study was to compare the outcomes of LDKT vs DDKT performed in children at a single center. Retrospective chart review of pediat...

journal_title：Pediatric transplantation

authors： Pérez-Bertólez S,Barrero R,Fijo J,Alonso V,Ojha D,Fernández-Hurtado MÁ,Martínez J,León E,García-Merino F

更新日期：2017-05-01 00:00:00

abstract：:BM remains an important source of stem cells. The BM characteristics change with age but the estimation of CD34 calculation of one CD34+ cell per 100 nucleated cells is used for all donors including pediatric donors in the operating room before getting the actual CD34 count. In order to see whether this formula is app...

journal_title：Pediatric transplantation

authors： Ince EU,Ileri T,Dogu F,Ates C,Cakmakli H,Dalva K,Ikinciogullari A,Uysal Z,Ertem M

更新日期：2015-06-01 00:00:00

abstract：:This study analyzes the data reported to the Korean Cord Blood Registry between 1994 and 2008, involving children and adolescents with non-malignant diseases. Sixty-five patients were evaluated in this study: SAA (n = 24), iBMFS, (n = 16), and primary immune deficiency/inherited metabolic disorder (n = 25). The CI of ...

journal_title：Pediatric transplantation

authors： Park M,Lee YH,Kang HR,Lee JW,Kang HJ,Park KD,Shin HY,Ahn HS,Baek HJ,Kook H,Hwang TJ,Lee JW,Chung NG,Cho B,Kim HK,Lee SH,Yoo KH,Sung KW,Koo HH,Koh KN,Im HJ,Seo JJ,Park JE,Lim YJ,Lyu CJ,Lee JM,Hah JO,K

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVES:To study the characteristics and the predictors of survival observed in our pediatric live-donor renal transplant recipients with an allograft that functioned for more than 10 yr. METHODS:One hundred fifteen children underwent renal transplantation between 1976 and 1995. Of these, 30 had functioning allogra...

journal_title：Pediatric transplantation

authors： El-Husseini AA,Foda MA,Osman YM,Sobh MA

更新日期：2006-05-01 00:00:00

abstract：:Alternate donor HSCT for thalassemia major from a matched unrelated donor or haploidentical family donor is a feasible therapeutic option in children with no matched family donor. Aggressive pretransplant immunosuppression, reduced toxicity conditioning, and PTCY result in excellent thalassemia-free survival. We descr...

journal_title：Pediatric transplantation

authors： Vellaichamy Swaminathan V,Ravichandran N,Ramanan KM,Meena SK,Varla H,Ramakrishnan B,Jayakumar I,Uppuluri R,Raj R

更新日期：2020-10-27 00:00:00

abstract：:Focal segmental glomerulosclerosis (FSGS) occurring in association with cytomegalovirus (CMV) infection in a renal transplant patient with no previous history of FSGS has rarely been reported. We present a case of a 16-year-old renal transplant recipient who developed acute hepatitis, leukopenia, nephrotic syndrome, a...

journal_title：Pediatric transplantation

authors： Wynd E,Stewart A,Burke J

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:The hybrid stage 1 palliation for hypoplastic left heart syndrome (HLHS) was first described in 1993 as a bridge to heart transplant for HLHS. There are limited data on this strategy as primary heart transplantation for HLHS has become less common. METHODS:This is an observational, single-center study compa...

journal_title：Pediatric transplantation

authors： Morray BH,Albers EL,Jones TK,Kemna MS,Permut LC,Law YM

更新日期：2018-12-01 00:00:00

abstract：:BKV reactivation is associated with impaired graft function in kidney transplant patients. The objective of our study was to determine the prevalence of BKV infection in consecutive pediatric kidney transplant recipients at our center. Fifty-eight pediatric kidney transplant recipients were studied. The mean age at sc...

journal_title：Pediatric transplantation

authors： Momynaliev KT,Gorbatenko EV,Shevtsov AB,Gribanov OG,Babenko NN,Kaabak MM

更新日期：2012-03-01 00:00:00

abstract：:The risk of adverse outcomes for pediatric renal transplant patients is highest during the transition from pediatric to adult care. While there have been many studies focus on graft failure and death, loss to follow-up likely plays a large role in patient outcomes. We hypothesize patients are lost to follow-up during ...

journal_title：Pediatric transplantation

authors： Hung YC,Williams JE,Bababekov YJ,Rickert CG,Chang DC,Yeh H

更新日期：2019-11-01 00:00:00

abstract：:DTI indices have been associated with cellular rejection in adult heart transplant recipients, but their predictive value in pediatric recipients is unknown. The purpose of this study was to evaluate DTI measures in the detection of cellular and AMR in pediatric heart transplant recipients. One hundred and forty-eight...

journal_title：Pediatric transplantation

authors： Behera SK,Trang J,Feeley BT,Levi DS,Alejos JC,Drant S

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Cryptosporidium enteritis can be devastating in the immunocompromised host. In pediatric liver transplant recipients, infection may be complicated by prolonged carriage of the parasite, rejection, and biliary tree damage and fibrosis. Herein, we report on six patients and their long-term outcomes following c...

journal_title：Pediatric transplantation

authors： Fischer RT,Day JC,Wasserkrug H,Faseler M,Kats A,Daniel JF,Slowik V,Andrews W,Hendrickson RJ

更新日期：2020-12-01 00:00:00

abstract：:Bartter's syndrome (BS) is an incurable genetic disease, with variable response to supportive therapy relating to fluid and electrolyte management. Poor control or therapy non-compliance may result in frequent life threatening episodes of dehydration, acidosis and hypokalemia, with resultant adverse effects on patient...

journal_title：Pediatric transplantation

authors： Chaudhuri A,Salvatierra O Jr,Alexander SR,Sarwal MM

更新日期：2006-03-01 00:00:00

abstract：:HHV type 6 has been reported with enhanced pathogenicity in immunocompromised patients. Herein, we report about a two-yr-old girl who experienced primary HHV 6 infection after liver transplantation. She clinically presented with graft rejection and necrotic hepatitis as well as high fever, pneumonitis with respiratory...

journal_title：Pediatric transplantation

authors： Dohna-Schwake C,Fiedler M,Gierenz N,Gerner P,Ballauf A,Breddemann A,Läer S,Baba HA,Hoyer PF

更新日期：2011-09-01 00:00:00

abstract：:HSCT is associated with a high risk of late morbidity. The aim of this study was to evaluate the frequency, time frame, risk factors, and possible etiology of pulmonary dysfunction following allogeneic HSCT in childhood. We evaluated the pulmonary function of 51 HSCT patients (>6 yr), by including FVC and FEV1 values ...

journal_title：Pediatric transplantation

authors： Madanat-Harjuoja LM,Valjento S,Vettenranta K,Kajosaari M,Dyba T,Taskinen M

更新日期：2014-09-01 00:00:00

abstract：:There are little data on prevalence of dyslipidemia in pediatric kidney TX recipients in the modern IS era. LP profiles of 38 TX recipients receiving triple IS with MMF, prednisone, and tacrolimus were compared with those of 11 children on HD using mixed model multiple linear regression analysis of repeated measures a...

journal_title：Pediatric transplantation

authors： Sgambat K,He J,McCarter RJ,Moudgil A

更新日期：2008-11-01 00:00:00

abstract：:Transplantation is the accepted mode of treatment for patients with end-stage organ disease affecting the heart, lungs, kidney, pancreas, liver and intestine. Long-term outcomes have significantly improved and the aim of management is no longer only long-term survival, but also focuses on quality of life especially in...

journal_title：Pediatric transplantation

authors： Spearman CW,McCulloch MI

更新日期：2014-11-01 00:00:00

abstract：:Heart transplantations have been performed in the Centre for Paediatric Heart Surgery at the Justus Liebig University in Giessen (Germany) since 1988. For further consultation and therapy, some affected children subsequently present at the Polyclinic for Paediatric Dentistry. In all these cases problematic oral findin...

journal_title：Pediatric transplantation

authors： Ansari F,Ferring V,Schulz-Weidner N,Wetzel WE

更新日期：2006-03-01 00:00:00

abstract：:MCs are important effector cells in a broad range of immune responses. Their role in liver allograft rejection is not clear. Twenty-one liver transplant recipients (mean age +/- s.d.; 10.2 +/- 4.1 yr) who experienced a rejection episode are included in this study. Biopsy specimens from normal livers (allograft biopsy ...

journal_title：Pediatric transplantation

authors： Arikan C,Nart D,Kilic M,Yuksekkaya HA,Aydogdu S

更新日期：2008-05-01 00:00:00

abstract：:The thymus gland possesses the ability to regrow in children leading to a newly developed anterior mediastinal mass. This condition may represent a rebound phenomenon during recovery from a stressful event such as post-chemotherapy and hence was described as RTH. RTH after LT has not been well documented. We are repor...

journal_title：Pediatric transplantation

authors： Wang TK,Kuo FY,Lee SY,Cheng YF,Elsarawy AM,Lin CC,Lin TL,Chen CL

更新日期：2018-07-24 00:00:00

abstract：:In patients with myocytolysis detected in endomyocardial biopsy, there is a tendency towards a shift of ventricular electrical axes from normal to strain pattern on surface ECG. Their 12-lead signal-averaged electrocardiogram (SAECG) show a significant increase in filtered QRS duration (QRSD) compared with those with ...

journal_title：Pediatric transplantation

authors： Bennhagen RG,Sörnmo L,Pahlm O,Pesonen E

更新日期：2005-12-01 00:00:00

abstract：:There is increasing evidence that DSA are associated with poor graft survival, although there are little data in children. We aimed to describe the incidence of DSA in this group and to determine correlation with graft survival. HLA antibodies were analysed in 59 paediatric cardiac transplant recipients. Mean age 10.4...

journal_title：Pediatric transplantation

authors： Irving C,Carter V,Parry G,Hasan A,Kirk R

更新日期：2011-03-01 00:00:00

abstract：:We assessed our long-term experience with regards to the safety and efficacy of MMF in our pediatric renal transplant population and compared it retrospectively to our previous non-MMF immunosuppressive regimen. Forty-seven pediatric renal transplants received MMF as part of their immunosuppressive protocol in the per...

journal_title：Pediatric transplantation

authors： Raheem OA,Kamel MH,Daly PJ,Mohan P,Little DM,Awan A,Hickey DP

更新日期：2011-05-01 00:00:00

abstract：:Severe portopulmonary hypertension (POPH) is a contraindication for liver transplantation (LT) because of the high risk of postoperative heart failure. The early detection of POPH is important for patients with biliary atresia (BA). Brain natriuretic peptide (BNP) is known to be correlated with liver fibrosis in patie...

journal_title：Pediatric transplantation

authors： Yoshimaru K,Matsuura T,Takahashi Y,Yanagi Y,Nagata H,Ohga S,Taguchi T

更新日期：2018-08-01 00:00:00

abstract：:IMI are emerging as an important cause of mortality and morbidity among the growing number of immunocompromised children. A retrospective chart review was performed in all patients with a proven diagnosis of IMI over an eight-yr period (1997-2004) at The Hospital for Sick Children, Toronto, Canada to document the inci...

journal_title：Pediatric transplantation

authors： Al-Rezqi A,Hawkes M,Doyle J,Richardson SE,Allen U

更新日期：2009-08-01 00:00:00