Rebound thymic hyperplasia after liver transplantation for a child with biliary atresia; a case report.

Abstract:

:The thymus gland possesses the ability to regrow in children leading to a newly developed anterior mediastinal mass. This condition may represent a rebound phenomenon during recovery from a stressful event such as post-chemotherapy and hence was described as RTH. RTH after LT has not been well documented. We are reporting an infant with BA who underwent LT and presented with a symptomless anterior mediastinal mass, detected on follow-up imaging 6 months thereafter. Surgical partial excision was performed to rule out other differential diagnoses of a solid mass in the anterior mediastinum of an infant particularly lymphoma-that may arise as post-transplant lymphoproliferative disorder-and teratoma, as well as the other aggressive lesions such as thymoma and thymic carcinoma. The final pathological analysis revealed true thymic hyperplasia, consistent with RTH. The diagnosis of RTH should be considered for a child presenting by anterior mediastinal mass after LT.

journal_name

Pediatr Transplant

authors

Wang TK,Kuo FY,Lee SY,Cheng YF,Elsarawy AM,Lin CC,Lin TL,Chen CL

doi

10.1111/petr.13251

subject

Has Abstract

pub_date

2018-07-24 00:00:00

pages

e13251

eissn

1397-3142

issn

1399-3046

pub_type

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