Donor-specific HLA antibodies in paediatric cardiac transplant recipients are associated with poor graft survival.

abstract：:Despite significant interest by pediatric transplant patients in meeting others who have undergone transplantation, geographic distances combined with their daily routines make this difficult. This mixed-method study describes the use of Zora, a Web-based virtual community designed to create a support system for these...

journal_title：Pediatric transplantation

authors： Bers MU,Beals LM,Chau C,Satoh K,Blume ED,DeMaso DR,Gonzalez-Heydrich J

更新日期：2010-03-01 00:00:00

abstract：:Organ transplants between genetically different individuals elicit powerful immune responses that invariably cause rejection in the absence of immune suppression. Among the immune responses elicited by organ allografts, B-cell responses causing antibody-mediated rejection are one of the most vexing. However, recent ad...

journal_title：Pediatric transplantation

authors： Balin SJ,Platt JL,Cascalho M

更新日期：2008-08-01 00:00:00

abstract：:CEP is a rare inborn error of porphyrin-heme synthesis. Clinical manifestations can range from mild to severe and include erythrodontia, reddish-colored urine, and hemolytic anemia that can be mild or severe and may result in splenomegaly. Completely avoiding exposure to the sun is crucial. Attempts to reduce erythrop...

journal_title：Pediatric transplantation

authors： Faraci M,Morreale G,Boeri E,Lanino E,Dallorso S,Dini G,Scuderi F,Cohen A,Cappelli B

更新日期：2008-02-01 00:00:00

abstract：:We present the unique case of a pediatric patient who received chemotherapy for a diagnosis of CD, while mechanically supported with a Berlin EXCOR LVAD secondary to restrictive cardiomyopathy. A four-yr-old previously healthy male with restrictive cardiomyopathy required MCS after cardiac arrest but was diagnosed wit...

journal_title：Pediatric transplantation

authors： Thomas TO,Chandrakasan S,O'Brien M,Jefferies JL,Ryan TD,Wilmot I,Baker ML,Madueme PC,Morales D,Lorts A

更新日期：2015-02-01 00:00:00

abstract：:Biliary atresia is defined as partial or total obliteration of the extra-hepatic bile ducts. In advanced cases, liver transplantation (LTx) is considered the most appropriate treatment. This report describes a female patient whose biliary atresia and subsequent cirrhosis required LTx at 1 yr of age. Macroscopic inspec...

journal_title：Pediatric transplantation

authors： Bilezikçi B,Demirhan B,Kiyici H,Haberal M

更新日期：2001-02-01 00:00:00

abstract：:Pediatric cardiac transplant has become increasingly frequent in the last decade and survival rates have improved remarkably. Outcome research on this population suggests that the majority of children have the capacity for healthy adaptation although 25-40% have been shown to have some type of psychiatric difficulties...

journal_title：Pediatric transplantation

authors： Weil CM,Rodgers S,Rubovits S

更新日期：2006-12-01 00:00:00

abstract：:In patients with myocytolysis detected in endomyocardial biopsy, there is a tendency towards a shift of ventricular electrical axes from normal to strain pattern on surface ECG. Their 12-lead signal-averaged electrocardiogram (SAECG) show a significant increase in filtered QRS duration (QRSD) compared with those with ...

journal_title：Pediatric transplantation

authors： Bennhagen RG,Sörnmo L,Pahlm O,Pesonen E

更新日期：2005-12-01 00:00:00

abstract：:BM remains an important source of stem cells. The BM characteristics change with age but the estimation of CD34 calculation of one CD34+ cell per 100 nucleated cells is used for all donors including pediatric donors in the operating room before getting the actual CD34 count. In order to see whether this formula is app...

journal_title：Pediatric transplantation

authors： Ince EU,Ileri T,Dogu F,Ates C,Cakmakli H,Dalva K,Ikinciogullari A,Uysal Z,Ertem M

更新日期：2015-06-01 00:00:00

abstract：:MCs are important effector cells in a broad range of immune responses. Their role in liver allograft rejection is not clear. Twenty-one liver transplant recipients (mean age +/- s.d.; 10.2 +/- 4.1 yr) who experienced a rejection episode are included in this study. Biopsy specimens from normal livers (allograft biopsy ...

journal_title：Pediatric transplantation

authors： Arikan C,Nart D,Kilic M,Yuksekkaya HA,Aydogdu S

更新日期：2008-05-01 00:00:00

abstract：:I was asked to write this article to share with medical professionals, my view as a parent with a child who has special needs and needs a transplant. It is a detailed story from a parent's point of view on what it is like to have a child with special needs with serious medical complications and how I went about findin...

journal_title：Pediatric transplantation

authors： Carney MT

更新日期：2021-02-01 00:00:00

abstract：:Alternate donor HSCT for thalassemia major from a matched unrelated donor or haploidentical family donor is a feasible therapeutic option in children with no matched family donor. Aggressive pretransplant immunosuppression, reduced toxicity conditioning, and PTCY result in excellent thalassemia-free survival. We descr...

journal_title：Pediatric transplantation

authors： Vellaichamy Swaminathan V,Ravichandran N,Ramanan KM,Meena SK,Varla H,Ramakrishnan B,Jayakumar I,Uppuluri R,Raj R

更新日期：2020-10-27 00:00:00

abstract：:The waiting period for an organ transplant has been described as a time of tremendous uncertainty and vulnerability, posing unique challenges and stressors for pediatric transplant candidates and their families. It has been identified as the most stressful stage of the transplant journey, yet little attention has been...

journal_title：Pediatric transplantation

authors： Anthony SJ,Annunziato RA,Fairey E,Kelly VL,So S,Wray J

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:ADH is a rare and potentially fatal complication following LT. In this study, a systematic review was completed to identify risk factors which may contribute to ADH. METHODS:Transplant databases at three LT programs were reviewed. Four pediatric and zero adult cases were identified. Next, a systematic revie...

journal_title：Pediatric transplantation

authors： Emamaullee JA,Nekrasov V,Gilmour S,Kneteman N,Yanni G,Kohli R,Thomas D,Genyk Y

更新日期：2018-12-01 00:00:00

abstract：:There is a shortage of pediatric donor hearts for waitlisted children, and yet nearly 50% of organs offered are not transplanted. Donor quality is often cited as a reason for declining organs offered from donors infected with influenza, presumably due to concern about disease transmission at transplant leading to seve...

journal_title：Pediatric transplantation

authors： Smith CJ,McCulloch MD,Shirley DA,L'Ecuyer TJ

更新日期：2019-12-01 00:00:00

abstract：:Children (defined as under 18 yr of age) account for approximately 12.5% of all liver transplants in the United States. Even though the annual number of liver transplantation procedures remains relatively constant, the population of long-term survivors of liver transplantation has grown. Presently, the population of l...

journal_title：Pediatric transplantation

authors： Bucuvalas JC,Ryckman FC

更新日期：2002-02-01 00:00:00

abstract：:The clinical utility of tacrolimus monitoring in adults has been well documented. The present study compared tacrolimus monitoring in a pediatric population of 34 liver transplant patients in four US centers with an adult population of 111 patients in six US centers. Subjects (adult and pediatric) were evaluated, at d...

journal_title：Pediatric transplantation

authors： MacFarlane GD,Venkataramanan R,McDiarmid SV,Pirsch JD,Scheller DG,Ersfeld DL,Fitzsimmons WE

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Scientific advancements are occurring in cardiac xenotransplantation (XTx). However, there have been religious and social concerns surrounding this allotransplantation alternative. The purpose of this study was to explore the acceptance of XTx among stakeholders of the congenital heart disease (CHD) communit...

journal_title：Pediatric transplantation

authors： Padilla LA,Rhodes L,Sorabella RA,Hurst DJ,Cleveland DC,Dabal RJ,Cooper DK,Paris W,Carlo WF

更新日期：2020-10-06 00:00:00

abstract：:There is a limited supply of organs for all those who need them for survival. Thus, careful decisions must be made about who is listed for transplant. Studies show that manifesting genetic disease can impact listing eligibility. What has not yet been studied is the impact genetic risks for future disease have on a pat...

journal_title：Pediatric transplantation

authors： Graf M,Char D,Hanson-Kahn A,Magnus D

更新日期：2019-06-01 00:00:00

abstract：:Immunosuppression regimens after liver transplantation focus mainly on preventing rejection and subsequent graft loss. However, in children, morbidity and mortality rates from infections exceed those from rejection after transplant, and immunosuppression can hinder growth, renal function, and graft tolerance. We hypot...

journal_title：Pediatric transplantation

authors： Turmelle YP,Nadler ML,Anderson CD,Doyle MB,Lowell JA,Shepherd RW

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Little data exist on immunosuppressive drug absorption in children with short bowel syndrome and intestinal failure associated liver disease (SBS-IFALD). AIM:To evaluate the absorption of immunosuppressive medications in children with SBS-IFALD undergoing isolated liver transplantation (iLTx). METHODS:A re...

journal_title：Pediatric transplantation

authors： Olio DD,Gupte G,Sharif K,Murphy MS,Lloyd C,McKiernan PJ,Kelly DA,Beath SV

更新日期：2006-09-01 00:00:00

abstract：:Hypogammaglobulinemia is common after pediatric SCT and IgG replacement is recommended. Some children will have a prolonged hypogammaglobulinemia but may have poor venous access which impedes further iv IgG replacement. In primary antibody deficiencies, sc IgG replacement, performed by parents at home, has been shown ...

journal_title：Pediatric transplantation

authors： Sundin M,Nordin K,Jostemyr Y,Winiarski J

更新日期：2012-12-01 00:00:00

abstract：:PTLD is a serious complication of both solid organ and BMT. This study assessed whether (18) F-FDG PET, when added to CT scan, had additional value in the initial evaluation of PTLD in pediatric patients and whether PET/CT at baseline can reliably guide biopsy. This retrospective study evaluated 34 consecutive pediatr...

journal_title：Pediatric transplantation

authors： Vali R,Punnett A,Bajno L,Moineddin R,Shammas A

更新日期：2015-12-01 00:00:00

abstract：:Recipient lymphocytes are crucial for direct and indirect pathways of allorecognition. We proposed that the administration of alemtuzumab several weeks pretransplantation could eradicate peripheral lymphatic cells and promote donor-specific acceptance. This was a single-center, retrospective review of 101 consecutive ...

journal_title：Pediatric transplantation

authors： Kaabak MM,Babenko NN,Shapiro R,Maschan AA,Zokoev AK,Schekaturov SV,Vyunkova JN,Dymova OV

更新日期：2017-08-01 00:00:00

abstract：:SR-aGVHD remains a significant cause of morbidity and mortality in allogeneic HCT recipients. Alemtuzumab has been used with success in adult patients but has not been studied in the pediatric setting. To estimate the effectiveness of alemtuzumab for the treatment of SR-aGVHD in pediatric patients, we retrospectively ...

journal_title：Pediatric transplantation

authors： Khandelwal P,Lawrence J,Filipovich AH,Davies SM,Bleesing JJ,Jordan MB,Mehta P,Jodele S,Grimley MS,Kumar A,Myers K,Marsh RA

更新日期：2014-02-01 00:00:00

abstract：:Much is still unknown about LUT function after receiving renal graft. Graft function was the main focus of different studies discussing the same issue. However, these studies ignored the effects of the graft on lower tract function and more demand for bladder cycling and growth of the child. Therefore, we aimed at eva...

journal_title：Pediatric transplantation

authors： Aboulela W,Fawzy AM,Abdelmawla MA,Salah DM,Eldin MS,Mohamed Anwar AZ,El Ghoneimy M,Shouman AM,Shoukry AI,Bazaraa H,Tawfiek ER,Fadel F,Badawy H,Morsi HA,Ghoneima W

更新日期：2020-09-01 00:00:00

abstract：:INFVA is an important cause of pulmonary infections in patients receiving BMT, and is associated with considerable morbidity and mortality for a readily preventable and treatable infection. Few studies have addressed the impact of the new neuraminidase inhibitors in the prognosis of influenza after BMT. The aim of thi...

journal_title：Pediatric transplantation

authors： Mellouli F,Ouederni M,Dhouib N,Hajkacem MA,Slim A,Bejaoui M

更新日期：2010-03-01 00:00:00

abstract：:Renal transplantation is the treatment of choice for children with ESRD offering advantages of improved survival, growth potential, cognitive development, and quality of life. The aim of our study was to compare the outcomes of LDKT vs DDKT performed in children at a single center. Retrospective chart review of pediat...

journal_title：Pediatric transplantation

authors： Pérez-Bertólez S,Barrero R,Fijo J,Alonso V,Ojha D,Fernández-Hurtado MÁ,Martínez J,León E,García-Merino F

更新日期：2017-05-01 00:00:00

abstract：:DTI indices have been associated with cellular rejection in adult heart transplant recipients, but their predictive value in pediatric recipients is unknown. The purpose of this study was to evaluate DTI measures in the detection of cellular and AMR in pediatric heart transplant recipients. One hundred and forty-eight...

journal_title：Pediatric transplantation

authors： Behera SK,Trang J,Feeley BT,Levi DS,Alejos JC,Drant S

更新日期：2008-03-01 00:00:00

abstract：:The development of malignancy in a renal transplant graft is an uncommon phenomenon. A renal neoplasm developing in the adult donor kidney of a pediatric transplant recipient has only rarely been reported. We report a case of collecting duct carcinoma arising in association with BK virus nephropathy in an adult living...

journal_title：Pediatric transplantation

authors： Emerson LL,Carney HM,Layfield LJ,Sherbotie JR

更新日期：2008-08-01 00:00:00

abstract：:A generic version of tacrolimus was approved for use in the USA in August 2009. These narrow therapeutic index generics are tested for bioequivalence only in adults. No data are available on generic tacrolimus levels in children with allografts. Four patients with stable renal allografts in our pediatric program were ...

journal_title：Pediatric transplantation

authors： Abdulnour HA,Araya CE,Dharnidharka VR

更新日期：2010-12-01 00:00:00