ABO-incompatible deceased donor pediatric liver transplantation: Novel titer-based management protocol and outcomes.

abstract：:Recurrent FSGS is a major challenge in the field of nephrology. To clarify the role of NPHS2 defects in the pathogenesis of FSGS recurrence, we sequenced all eight exons of NPHS2 in 11 Japanese pediatric FSGS patients with or without post-transplant recurrence. All patients had biopsy-proven primary FSGS, had no famil...

journal_title：Pediatric transplantation

authors： Furue T,Hattori M,Tsukaguchi H,Kitamura A,Oomori T,Ogino D,Nakakura H,Ashida A,Miura K,Hisano M,Takahashi K,Chikamoto H,Akioka Y,Sakano T

更新日期：2008-05-01 00:00:00

abstract：:Calcineurin inhibitors post-renal transplantation are recognized to cause tubulopathies in the form of hyponatremia, hyperkalemia, and acidosis. Sodium supplementation may be required, increasing medication burden and potentially resulting in poor compliance. Fludrocortisone has been beneficial in addressing tubulopat...

journal_title：Pediatric transplantation

authors： Ali SR,Shaheen I,Young D,Ramage I,Maxwell H,Hughes DA,Athavale D,Shaikh MG

更新日期：2018-03-01 00:00:00

abstract：:FA is an autosomal recessive disorder characterized by small stature and renal abnormalities. FA can lead to progressive bone marrow failure, myelodysplastic syndrome, or acute leukemia. Using a multidisciplinary team approach, we managed a 3-yr-old boy with FA who simultaneously developed renal and hematopoietic fail...

journal_title：Pediatric transplantation

authors： Vincent CL,Primack WA,Hipps J,Kasow KA

更新日期：2016-02-01 00:00:00

abstract：:SR-aGVHD remains a significant cause of morbidity and mortality in allogeneic HCT recipients. Alemtuzumab has been used with success in adult patients but has not been studied in the pediatric setting. To estimate the effectiveness of alemtuzumab for the treatment of SR-aGVHD in pediatric patients, we retrospectively ...

journal_title：Pediatric transplantation

authors： Khandelwal P,Lawrence J,Filipovich AH,Davies SM,Bleesing JJ,Jordan MB,Mehta P,Jodele S,Grimley MS,Kumar A,Myers K,Marsh RA

更新日期：2014-02-01 00:00:00

abstract：:There is currently no way to diagnose a rejection before a change in serum creatinine. This had led some to start doing SB, but little data exist on the utility and safety of SB in pediatric patients. There is also little known on practice patterns of pediatric nephrologists. A retrospective review of pediatric kidney...

journal_title：Pediatric transplantation

authors： Nazario M,Nicoara O,Becton L,Self S,Hill J,Mack E,Evans M,Twombley K

更新日期：2018-06-01 00:00:00

abstract：:The emergence of oseltamivir-resistant 2009 H1N1 influenza virus (conferred by the H275Y substitution in NA) during therapy or prophylaxis in immunocompromised patients is a serious concern. The optimal therapy for immunosuppressed patients with oseltamivir-resistant 2009 H1N1 influenza virus is unknown and few option...

journal_title：Pediatric transplantation

authors： Shetty AK,Ross GA,Pranikoff T,Gubareva LV,Sechrist C,Guirand DM,Abramson J,Lin JJ

更新日期：2012-08-01 00:00:00

abstract：:EPVO is a common cause of prehepatic portal hypertension in pediatric patients and sometimes results in cavernous transformation of the PV. We herein present the cases of two patients who underwent LDLT for EPVO with post-Kasai biliary atresia. PV reconstruction was performed with a porto-left gastric vein anastomosis...

journal_title：Pediatric transplantation

authors： Kitajima T,Sakamoto S,Uchida H,Hamano I,Kobayashi M,Kanazawa H,Fukuda A,Kasahara M

更新日期：2013-05-01 00:00:00

abstract：:Nonalcoholic steatohepatitis (NASH) is the most severe form of non-alcoholic fatty liver disease (NAFLD). The aim of our study was to highlight NASH as a rare but possible problem in children. We present a case of 13-yr-boy with a well-established diagnosis of liver cirrhosis secondary to NASH, who underwent orthotopi...

journal_title：Pediatric transplantation

authors： Jankowska I,Socha P,Pawlowska J,Teisseyre M,Gliwicz D,Czubkowski P,Kalicinski P,Cielecka-Kuszyk J,Socha J

更新日期：2007-11-01 00:00:00

abstract：:Vascular complications remain the most common cause of early renal allograft loss in patients with end-stage renal failure. Underlying thrombophilic disorders increase the risk of early graft thrombosis. A male adolescent with high-risk thrombophilia because of combined heterozygous factor V Leiden (G1691A) and prothr...

journal_title：Pediatric transplantation

authors： John U,Kentouche K,Nowak G,Schubert J,Misselwitz J

更新日期：2006-02-01 00:00:00

abstract：:The clinical significance of parvovirus B19 infection in pediatric solid-organ and bone marrow transplanted patients is unclear. The overall prevalence of parvovirus B19 infection in these patients is about 1-2% during the first year after transplantation. The most common symptom is anemia, but leukopenia and thromboc...

journal_title：Pediatric transplantation

authors： Broliden K

更新日期：2001-10-01 00:00:00

abstract：:The potentially curative role of allogeneic hematopoietic cell transplantation (HCT) in neoplastic and non-neoplastic diseases is offset by the substantial risks of morbidity and mortality from complications of the intensive myeloablative and immunosuppressive preparative regimen. These regimen-related toxicities have...

journal_title：Pediatric transplantation

authors： Schwartz JE,Yeager AM

更新日期：2003-06-01 00:00:00

abstract：:Intra-operative arterial vasospasm during pediatric renal transplantation is an urgent clinical situation resulting in end-organ ischemia, associated changes in parenchymal turgor and color, diminished flow on ultrasound, and if left untreated, allograft loss. We hypothesized that intra-operative intra-arterial inject...

journal_title：Pediatric transplantation

authors： Penna FJ,Harvey E,John P,Armstrong D,Luginbuehl I,Odeh RI,Alyami F,Koyle MA,Lorenzo AJ

更新日期：2016-05-01 00:00:00

abstract：:There are little data on prevalence of dyslipidemia in pediatric kidney TX recipients in the modern IS era. LP profiles of 38 TX recipients receiving triple IS with MMF, prednisone, and tacrolimus were compared with those of 11 children on HD using mixed model multiple linear regression analysis of repeated measures a...

journal_title：Pediatric transplantation

authors： Sgambat K,He J,McCarter RJ,Moudgil A

更新日期：2008-11-01 00:00:00

abstract：:An increasing number of individuals with end-stage renal disease have become sensitized to human leukocyte antigens (HLA). Sensitization can have a profound impact on the likelihood of obtaining a requisite negative crossmatch (-XM) with a potential donor. Technologic breakthroughs in our ability to diagnose antibody-...

journal_title：Pediatric transplantation

authors： Montgomery RA,Zachary AA

更新日期：2004-12-01 00:00:00

abstract：:  FSGS has a high recurrence rate after renal transplantation. To examine the effects of the use of preemptive and post-transplant PP on recurrence and graft outcome, we conducted a retrospective study on 34 pediatric patients (mean age 13±5 yr) with biopsy-proven pretransplant FSGS and who underwent a renal transplan...

journal_title：Pediatric transplantation

authors： Gonzalez E,Ettenger R,Rianthavorn P,Tsai E,Malekzadeh M

更新日期：2011-08-01 00:00:00

abstract：:MCs are important effector cells in a broad range of immune responses. Their role in liver allograft rejection is not clear. Twenty-one liver transplant recipients (mean age +/- s.d.; 10.2 +/- 4.1 yr) who experienced a rejection episode are included in this study. Biopsy specimens from normal livers (allograft biopsy ...

journal_title：Pediatric transplantation

authors： Arikan C,Nart D,Kilic M,Yuksekkaya HA,Aydogdu S

更新日期：2008-05-01 00:00:00

abstract：:Children receiving HCT loose protective immunity to vaccines received pre-HCT. Therefore, revaccination post-HCT is of major importance. In Denmark, a vaccination schedule with fewer doses post-HCT has been used, including two doses for diphtheria, tetanus, polio, measles, mumps, and rubella, and one dose only for Hae...

journal_title：Pediatric transplantation

authors： Jensen L,Poulsen A,Nygaard U,Scheike T,Riis MS,Pedersen FK,Heilmann C

更新日期：2020-02-01 00:00:00

abstract：:This retrospective case series reviews our center's experience with sirolimus and a CNI as alternative therapy for the treatment of PTAH. It also characterizes regulatory T cells (Tregs) in PTAH. LT recipients with PTAH who had received or were receiving treatment with sirolimus were retrospectively identified (n = 12...

journal_title：Pediatric transplantation

authors： Ekong UD,Mathew J,Melin-Aldana H,Wang D,Alonso EM

更新日期：2012-03-01 00:00:00

abstract：:Thrombosis after kidney transplantation may result in catastrophic outcomes, including graft loss. Thrombophilia has been implicated in post-transplant thrombosis; data, however, are inconclusive on the impact of acquired and inherited thrombophilia and resultant thrombosis in renal graft recipients. We aimed to evalu...

journal_title：Pediatric transplantation

authors： Bock ME,Bobrowski AE,Bhat R

更新日期：2019-02-01 00:00:00

abstract：:Prematurity and very low birthweight have often been considered relative contraindications to neonatal organ donation. Organ procurement from neonatal donors is further complicated by unclear guidelines regarding neonatal brain death. We report a successful case of multivisceral transplantation using a graft from a 10...

journal_title：Pediatric transplantation

authors： Cauley RP,Suh MY,Kamin DS,Lillehei CW,Jenkins RL,Jonas MM,Vakili K,Kim HB

更新日期：2012-12-01 00:00:00

abstract：:Antibody-mediated rejection (AMR) has recently been recognized as a significant and unique form of rejection that is not amenable to treatment with standard immunosuppressive medications aimed at modification of T-cell function. Recent interest in AMR and the role of B cells in rejection has been aided by the concomit...

journal_title：Pediatric transplantation

authors： Jordan SC,Vo AA,Tyan D,Nast CC,Toyoda M

更新日期：2005-06-01 00:00:00

abstract：:The waiting period for an organ transplant has been described as a time of tremendous uncertainty and vulnerability, posing unique challenges and stressors for pediatric transplant candidates and their families. It has been identified as the most stressful stage of the transplant journey, yet little attention has been...

journal_title：Pediatric transplantation

authors： Anthony SJ,Annunziato RA,Fairey E,Kelly VL,So S,Wray J

更新日期：2014-08-01 00:00:00

abstract：:The prospective cross-sectional study investigated the 6MWT performance in pediatric group of liver transplant recipients (6-17 yr, median post-transplantation time of 22 months) and compared to the normal values obtained in healthy children as well as evaluated the reproducibility of the 6MWT. We analyzed the relatio...

journal_title：Pediatric transplantation

authors： Maria da Silva R,Brunow de Carvalho W,Johnston C,Borba de Castro M,Manta Ferreira I,Patti CL,Anthero de Azevedo R,Miziara Gonzalez A,Moura Linhares M,Augusto Salzedas-Netto A

更新日期：2014-09-01 00:00:00

abstract：:The adjusted relative risk (aRR) for development of post-transplant lymphoproliferative disorder (PTLD) is higher in kidney transplant recipients receiving monoclonal antibody induction therapy, but the aRR between the different available polyclonal agents has not been investigated in detail. We analyzed data from the...

journal_title：Pediatric transplantation

authors： Dharnidharka VR,Stevens G

更新日期：2005-10-01 00:00:00

abstract：:PPCA has historically been considered detrimental to donor quality in LT, but transplantation of grafts from this group of donors is now routine. Our study aims to evaluate the outcomes associated with use of donors with a history of PPCA in the pediatric population. This study is a single-center retrospective analysi...

journal_title：Pediatric transplantation

authors： Schroering JR,Hathaway TJ,Kubal CA,Ekser B,Mihaylov P,Mangus RS

更新日期：2020-08-01 00:00:00

abstract：:A major risk faced by bone-marrow and solid organ transplant patients is the development of post-transplant lymphoproliferative disease or post-transplant lymphoma (PTLD). In pediatric transplantation, PTLD onset is often associated with a rapid rise in Epstein-Barr virus (EBV) load in peripheral blood mononuclear cel...

journal_title：Pediatric transplantation

authors： Orentas RJ,Schauer DW Jr,Ellis FW,Walczak J,Casper JT,Margolis DA

更新日期：2003-08-01 00:00:00

abstract：:We report a 10-yr-old boy who developed CIPS after a second allogeneic BMT for severe aplastic anemia. He received the second BMT from the same HLA-matched sibling donor 16 months after the first BMT due to secondary graft failure. The preparative regimen for the second BMT consisted of fludarabine, cyclophosphamide, ...

journal_title：Pediatric transplantation

authors： Nishikawa T,Okamoto Y,Tanabe T,Shinkoda Y,Kodama Y,Tsuru Y,Kawano Y

更新日期：2009-08-01 00:00:00

abstract：:PJP is known to cause significant morbidity and rarely death in immunosuppressed patients. The prevalence and outcomes of PJP in pediatric solid-organ transplant patients are not well established. This study utilizes data from the PHTS to establish the prevalence and outcome of PJP in pediatric heart transplant recipi...

journal_title：Pediatric transplantation

authors： Ng B,Dipchand A,Naftel D,Rusconi P,Boyle G,Zaoutis T,Edens RE

更新日期：2011-12-01 00:00:00

abstract：:The relationship between SES and outcomes surrounding pediatric cardiac transplantation is complex and influenced by recipient race. Broad-based studies of SES have not been performed. A retrospective review of all 5125 primary pediatric heart transplants performed in the United States between 2000 and 2011. Patients ...

journal_title：Pediatric transplantation

authors： Davies RR,Russo MJ,Reinhartz O,Maeda K,Rosenthal DN,Chin C,Bernstein D,Mallidi HR

更新日期：2013-09-01 00:00:00

abstract：:The aim of this study was to study the incidence of chronic renal dysfunction in patients with more than 5 yr of follow-up following liver transplantation and to evaluate the benefit of decreasing cyclosporine A (CsA) dose combined with mycophenolate mofetil (MMF) on renal function and immune response in these patient...

journal_title：Pediatric transplantation

authors： Ferraris JR,Duca P,Prigoshin N,Tambutti ML,Boldrini G,Cardoni RL,D'Agostino D

更新日期：2004-10-01 00:00:00