The conundrum of patients with obesity, exercise intolerance, elevated ventricular filling pressures and a measured ejection fraction in the normal range.

abstract：AIMS:To identify novel risk markers for incident heart failure using proteomic profiling of 80 proteins previously associated with cardiovascular pathology. METHODS AND RESULTS:Proteomic profiling (proximity extension assay) was performed in two community-based prospective cohorts of elderly individuals without heart ...

journal_title：European journal of heart failure

authors： Stenemo M,Nowak C,Byberg L,Sundström J,Giedraitis V,Lind L,Ingelsson E,Fall T,Ärnlöv J

更新日期：2018-01-01 00:00:00

abstract：AIMS:Exercise-derived parameters, specifically peak exercise oxygen uptake (peak VO2 ) and minute ventilation/carbon dioxide relationship slope (VE/VCO2 slope), have a pivotal prognostic value in heart failure (HF). It is unknown how the prognostic threshold of peak VO2 and VE/VCO2 slope has changed over the last 20 ye...

journal_title：European journal of heart failure

authors： Paolillo S,Veglia F,Salvioni E,Corrà U,Piepoli M,Lagioia R,Limongelli G,Sinagra G,Cattadori G,Scardovi AB,Metra M,Senni M,Bonomi A,Scrutinio D,Raimondo R,Emdin M,Magrì D,Parati G,Re F,Cicoira M,Minà C,Correale M

更新日期：2019-02-01 00:00:00

abstract：AIMS:The purpose of this study was to determine that the administration of an angiotensin converting enzyme (ACE) inhibitor enalapril would confer protection against doxorubicin-induced experimental heart failure, and attenuate the development of left ventricular dysfunction. METHODS:Seventeen dogs were chronically in...

journal_title：European journal of heart failure

authors： Vaynblat M,Shah HR,Bhaskaran D,Ramdev G,Davis WJ 3rd,Cunningham JN Jr,Chiavarelli M

更新日期：2002-10-01 00:00:00

abstract：AIMS:Chronic heart failure (CHF) due to left ventricular systolic dysfunction is associated with poor quality of life (QoL). This study aimed to assess factors affecting health-related QoL in CHF patients and their carers and the impact of QoL on clinical outcomes. METHODS AND RESULTS:Demographic, social, and clinical...

journal_title：European journal of heart failure

authors： Iqbal J,Francis L,Reid J,Murray S,Denvir M

更新日期：2010-09-01 00:00:00

abstract：AIMS:To compare the effects of lipophilic simvastatin and hydrophilic rosuvastatin on plasma adiponectin and glycated haemoglobin A1c (HbA1c) levels in patients with non-ischaemic chronic heart failure (NICHF). METHODS AND RESULTS:Seventy-one stable outpatients with NICHF, who were already receiving standard therapy f...

journal_title：European journal of heart failure

authors： Tsutamoto T,Yamaji M,Kawahara C,Nishiyama K,Fujii M,Yamamoto T,Horie M

更新日期：2009-12-01 00:00:00

abstract：AIMS:Calcium channel plays an important role in the autoimmune pathogenesis of idiopathic dilated cardiomyopathy (DCM). Autoantibodies have emerged as a new upstream target of sudden death in DCM. We sought to validate the hypothesis that autoantibodies against l-type calcium channel (CC-AAbs) are arrhythmogenic and le...

journal_title：European journal of heart failure

authors： Xiao H,Wang M,Du Y,Yuan J,Cheng X,Chen Z,Zou A,Wei F,Zhao G,Liao YH

更新日期：2011-03-01 00:00:00

abstract：:Many patients with Congestive Heart Failure (CHF) are anaemic. This anaemia is associated with more severe CHF and a higher incidence of mortality, hospitalisation and morbidity. The only way to prove that the anaemia is causing this worsening of CHF is to correct it. We review here some of the published papers about ...

journal_title：European journal of heart failure

authors： Silverberg DS,Wexler D,Iaina A,Schwartz D

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Recent advances in pharmacological and pacemaker-based treatments for heart failure (HF) have brought about significant improvements in left ventricular function. AIMS:To identify the proportion of treated systolic HF patients in whom left ventricular systolic function improves and/or returns to normal. ME...

journal_title：European journal of heart failure

authors： Murphy NF,O'Loughlin C,Ledwidge M,McCaffrey D,McDonald K

更新日期：2007-12-01 00:00:00

abstract：AIMS:Scarce data are available on the effect of the traditional Mediterranean diet (TMD) on heart failure biomarkers. We assessed the effect of TMD on biomarkers related to heart failure in a high cardiovascular disease risk population. METHODS AND RESULTS:A total of 930 subjects at high cardiovascular risk (420 men a...

journal_title：European journal of heart failure

authors： Fitó M,Estruch R,Salas-Salvadó J,Martínez-Gonzalez MA,Arós F,Vila J,Corella D,Díaz O,Sáez G,de la Torre R,Mitjavila MT,Muñoz MA,Lamuela-Raventós RM,Ruiz-Gutierrez V,Fiol M,Gómez-Gracia E,Lapetra J,Ros E,Serra-Majem L

更新日期：2014-05-01 00:00:00

abstract：:Aortic stenosis (AS) is the most frequent degenerative valvular heart disease in Western countries and its prevalence increases in parallel with the ageing process of the population. Heart failure (HF), defined by the presence of reduced left ventricular ejection fraction, may be present in up to a quarter of patients...

journal_title：European journal of heart failure

authors： Kamperidis V,Delgado V,van Mieghem NM,Kappetein AP,Leon MB,Bax JJ

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:In most animal models of chronic hemodynamic overload of the left ventricle (LV) as well as in human end stage heart failure, the sarcoplasmic reticulum (SR) Ca2+-ATPase (SERCA2a) mRNA levels are decreased in parallel with increased atrial natriuretic peptide (ANP) mRNA levels. The situation in the remote my...

journal_title：European journal of heart failure

authors： Prunier F,Chen Y,Gellen B,Heimburger M,Choqueux C,Escoubet B,Michel JB,Mercadier JJ

更新日期：2005-08-01 00:00:00

abstract：AIMS:The true incidence of life-threatening ventricular tachyarrhythmic events and the risk of sudden cardiac death in the early stage of peripartum cardiomyopathy (PPCM) are still unknown. We aimed to assess the usefulness of the wearable cardioverter/defibrillator (WCD) to bridge a potential risk for life-threatening...

journal_title：European journal of heart failure

authors： Duncker D,Haghikia A,König T,Hohmann S,Gutleben KJ,Westenfeld R,Oswald H,Klein H,Bauersachs J,Hilfiker-Kleiner D,Veltmann C

更新日期：2014-12-01 00:00:00

abstract：AIMS:Structural abnormalities causing cardiac deterioration in hypertensive heart disease (HHD) are poorly understood. The aim of the study was to evaluate left ventricular (LV) myocardial changes in patients with HHD and cardiac failure. METHODS AND RESULTS:Among 1229 patients undergoing an LV or biventricular endomy...

journal_title：European journal of heart failure

authors： Frustaci A,Francone M,Petrosillo N,Chimenti C

更新日期：2013-03-01 00:00:00

abstract：AIMS:Hemochromatosis is a condition in which iron loading impairs the function of many organs, including the heart. Congestive heart failure with left ventricular dilatation is commonly found in patients with hemochromatosis. Two missense mutations (C282Y and H63D) have been shown to be responsible for the majority of ...

journal_title：European journal of heart failure

authors： Goland S,Beilinson N,Kaftouri A,Shimoni S,Caspi A,Malnick SD

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:Infused C-type natriuretic peptide (CNP) was recently found to play a cardioprotective role in preventing myocardial ischaemia/reperfusion (I/R) injury and improving cardiac remodelling after myocardial infarction (MI) in rats. Our study aimed to investigate the effect of cardiomyocyte-specific CNP over-expre...

journal_title：European journal of heart failure

authors： Wang Y,de Waard MC,Sterner-Kock A,Stepan H,Schultheiss HP,Duncker DJ,Walther T

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Platelet-endothelial interactions modulated by adhesion molecules, may play an important role in the pathogenesis of congestive heart failure (CHF). Soluble levels of these molecules and platelet-derived substances are reportedly elevated in patients with CHF. However, no data are available on the plasma lev...

journal_title：European journal of heart failure

authors： Serebruany VL,Murugesan SR,Pothula A,Atar D,Lowry DR,O'Connor CM,Gurbel PA

更新日期：1999-08-01 00:00:00

abstract：:Alternations in gut microbial composition (i.e. loss of microbial diversity or 'gut dysbiosis') have been associated with heart failure with reduced ejection fraction (HFrEF). It has also been suggested that increased chronic low-level inflammation and immune system dysregulation seen in patients with HFrEF could be r...

journal_title：European journal of heart failure

authors： Madan S,Mehra MR

更新日期：2020-04-01 00:00:00

abstract：AIMS:Chronic hypertension may cause left ventricular hypertrophy (LVH). The role of matrix metalloproteinases (MMPs), tissue inhibitors of matrix metalloproteinases (TIMPs), and tenascin-C (Tn-C) splice variants in concentric vs. eccentric left ventricular remodelling has not been investigated. METHODS AND RESULTS:Ser...

journal_title：European journal of heart failure

authors： Franz M,Berndt A,Altendorf-Hofmann A,Fiedler N,Richter P,Schumm J,Fritzenwanger M,Figulla HR,Brehm BR

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:In patients with heart failure and reduced left ventricular ejection fraction, angiotensin receptor blockers have been found to reduce mortality and morbidity and to prevent or reverse left ventricular remodelling, compared to optimized background treatment. In light of these data, The Heart failure Endpoint...

journal_title：European journal of heart failure

authors： Konstam MA,Poole-Wilson PA,Dickstein K,Drexler H,Justice SJ,Komajda M,Malbecq W,Martinez FA,Neaton JD,Riegger GA,Guptha S

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVES:To compare the efficacy of the homeopathic Crataegus preparation Cralonin for non-inferiority to standard treatment for mild cardiac insufficiency. METHODS:Multicentre non-randomised cohort study in patients aged 50-75 years in New York Heart Association class II. Patients received Cralonin (n=110) or ACE i...

journal_title：European journal of heart failure

authors： Schröder D,Weiser M,Klein P

更新日期：2003-06-01 00:00:00

abstract：AIMS:We sought to test the utility of weight gain algorithms to predict episodes of worsening heart failure (WHF) using home-telemonitoring data collected as part of the TEN-HMS study. METHODS AND RESULTS:Simple rule-of-thumb (RoT) algorithms (i.e. 3 lbs in 1 day and 5 lbs in 3 days) and a moving average convergence d...

journal_title：European journal of heart failure

authors： Zhang J,Goode KM,Cuddihy PE,Cleland JG,TEN-HMS Investigators.

更新日期：2009-04-01 00:00:00

abstract：INTRODUCTION:Atrial fibrillation (AF) is common in patients with heart failure (HF) due to left ventricular systolic dysfunction (LVSD), with conflicting prognostic data. The aim of our study was to assess the prevalence and incidence of AF in patients with HF and to determine the prognostic impact of baseline AF and t...

journal_title：European journal of heart failure

authors： Corell P,Gustafsson F,Schou M,Markenvard J,Nielsen T,Hildebrandt P

更新日期：2007-03-01 00:00:00

abstract：:Cardiac contractility modulating (CCM) signals delivered by the OPTIMIZER System are being investigated as a treatment for medically refractory heart failure. Previous chronic studies of CCM have excluded patients with prolonged QRS and a cardiac resynchronization therapy (CRT) device. However, symptoms persist in mor...

journal_title：European journal of heart failure

authors： Butter C,Meyhöfer J,Seifert M,Neuss M,Minden HH

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:It has been suggested that oxidative stress may play a role in the pathogenesis of heart failure, this may have potential implications for therapeutic strategies. However, measures of oxidative stress are subject to confounding inaccuracies. IgG antibodies to oxidized LDL reflect exposure to the lipoprotein ...

journal_title：European journal of heart failure

authors： George J,Wexler D,Roth A,Barak T,Sheps D,Keren G

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Sleep disordered breathing (SDB), especially Cheyne-Stokes respiration (CSR) is common in patients with chronic heart failure (CHF). Adaptive servoventilation (ASV) was recently introduced to treat CSR in CHF. The aim of this study was to investigate the effects of ASV on CSR and CHF parameters. ME...

journal_title：European journal of heart failure

authors： Oldenburg O,Schmidt A,Lamp B,Bitter T,Muntean BG,Langer C,Horstkotte D

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:The incidence of ventricular tachyarrhythmias in ICD patients with cardiac resynchronisation therapy (CRT-D) is not well studied. AIM:To analyse event free survival in CRT-D patients with a primary or a secondary prophylactic ICD indication. METHODS:Prospective, single centre. Eighty-six patients, 44% with...

journal_title：European journal of heart failure

authors： Theuns DA,Thornton AS,Klootwijk AP,Scholten MF,Vantrimpont PJ,Balk AH,Jordaens LJ

更新日期：2005-10-01 00:00:00

abstract：AIM:The exercise Doppler echocardiographic stress test can be of interest in the management of asymptomatic patients with primary mitral regurgitation (MR). The resting brain natriuretic peptide (BNP) level is a good surrogate marker of the consequences of MR and is a powerful predictor of outcome. The incremental prog...

journal_title：European journal of heart failure

authors： Magne J,Mahjoub H,Pibarot P,Pirlet C,Pierard LA,Lancellotti P

更新日期：2012-11-01 00:00:00

abstract：:Heart failure is a major health problem and is associated with a high mortality and morbidity. Recently, the role of the genetic background in the onset and the development of the disease has been evidenced in both heart failure with and without systolic dysfunction and in familial and non-familial forms of this condi...

journal_title：European journal of heart failure

authors： Komajda M,Charron P,Tesson F

更新日期：1999-06-01 00:00:00

abstract：AIMS:We sought to describe the frequency, type and timing of clinical events, and delineate patterns in their transitions, after a first episode of heart failure (HF). METHODS AND RESULTS:In 1036 Framingham participants with new-onset HF (mean age 79 years; 53% women), we used mixture models to estimate probabilities ...

journal_title：European journal of heart failure

authors： Velagaleti RS,Larson MG,Enserro D,Song RJ,Vasan RS

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Hospital management of CHF and predictors of hospital mortality remain unclear. METHODS:To address these issues, we analyzed the hospital admissions for CHF during 1996 in a large university hospital. Patients discharged with the principal diagnosis of CHF were considered eligible for the study. RESULTS:Am...

journal_title：European journal of heart failure

authors： Grigioni F,Carinci V,Favero L,Bacchi Reggiani L,Magnani G,Potena L,Barbieri A,Magelli C,Branzi A,Magnani B

更新日期：2002-01-01 00:00:00