Abstract：
BACKGROUND:Hospital management of CHF and predictors of hospital mortality remain unclear. METHODS:To address these issues, we analyzed the hospital admissions for CHF during 1996 in a large university hospital. Patients discharged with the principal diagnosis of CHF were considered eligible for the study. RESULTS:Among the 1511 patients (3% of all discharges) who satisfied the inclusion criteria, 75% were treated in general medicine departments (GMD) and 22% in cardiology units (CU). Patients admitted to GMD were older than those treated in CU (79+/-10 vs. 68+/-15 years, P<0.001), included a higher proportion of females (56% vs. 37%, P<0.001), and presented a higher rate of hospital mortality (13% vs. 4%, P<0.001). The overall mean length of stay was 11+/-9 days. At multivariate analysis, length of stay was not associated with the department (i.e. GMD/CU) (P=0.273). CONCLUSIONS:CHF is a common lethal condition often requiring treatment in GMD. Length of stay appears to depend more on patients' characteristics than on differences in practice between GMD and CU. Patients admitted to GMD present higher rates of comorbidity and hospital mortality. Strategies are urgently needed to improve hospital management of CHF.
journal_name
Eur J Heart Failjournal_title
European journal of heart failureauthors
Grigioni F,Carinci V,Favero L,Bacchi Reggiani L,Magnani G,Potena L,Barbieri A,Magelli C,Branzi A,Magnani Bdoi
10.1016/s1388-9842(01)00204-5keywords:
subject
Has Abstractpub_date
2002-01-01 00:00:00pages
99-104issue
1eissn
1388-9842issn
1879-0844pii
S1388984201002045journal_volume
4pub_type
杂志文章abstract：BACKGROUND:Renal failure in heart failure is related to decreased cardiac output. However, little is known about its association with venous congestion. AIMS:To investigate the relationship between venous congestion and glomerular filtration rate (GFR) in patients with cardiac dysfunction. METHODS AND RESULTS:Right a...
journal_title：European journal of heart failure
pub_type： 临床试验,杂志文章
doi：10.1016/j.ejheart.2007.05.010
更新日期：2007-09-01 00:00:00
abstract：:Anti-beta-1-adrenergic receptor antibodies (anti-β1AR Abs) have long been implicated in the pathogenesis of dilated cardiomyopathy (DCM). It is believed that these autoantibodies bind to and constitutively stimulate the β1AR to promote pathological cardiac remodelling and β1AR desensitization and downregulation. The p...
journal_title：European journal of heart failure
pub_type： 杂志文章,评审
doi：10.1093/eurjhf/hft065
更新日期：2013-07-01 00:00:00
abstract：BACKGROUND:It has been suggested that oxidative stress may play a role in the pathogenesis of heart failure, this may have potential implications for therapeutic strategies. However, measures of oxidative stress are subject to confounding inaccuracies. IgG antibodies to oxidized LDL reflect exposure to the lipoprotein ...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/j.ejheart.2005.04.015
更新日期：2006-01-01 00:00:00
abstract：:Many patients with Congestive Heart Failure (CHF) are anaemic. This anaemia is associated with more severe CHF and a higher incidence of mortality, hospitalisation and morbidity. The only way to prove that the anaemia is causing this worsening of CHF is to correct it. We review here some of the published papers about ...
journal_title：European journal of heart failure
pub_type： 杂志文章,评审
doi：10.1016/j.ejheart.2008.06.015
更新日期：2008-09-01 00:00:00
abstract：BACKGROUND:Heart failure is common in diabetes and ischaemic heart disease is the most likely link. Still, it has been suggested that the relation extends beyond such disease. METHODS:7060 subjects with two or more visits in the Reykjavík Study were followed--during 30 years from 1967. All underwent oral glucose toler...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/j.ejheart.2007.07.017
更新日期：2007-10-01 00:00:00
abstract：:The use of erythropoietin (EPO) has revolutionized the treatment of anaemia associated with many conditions including chronic kidney disease (CKD). However, little is known of the cellular impact of EPO on the uraemic heart. The discovery that the EPO receptor (EPOR) is also expressed on non-haematopoietic cells inclu...
journal_title：European journal of heart failure
pub_type： 杂志文章,评审
doi：10.1093/eurjhf/hfp093
更新日期：2009-08-01 00:00:00
abstract：AIMS:In amyloid patients, cardiac involvement dramatically worsens functional capacity and prognosis. We sought to study how the cardiopulmonary exercise test (CPET) could help in functional assessment and risk stratification of patients with cardiac amyloidosis (CA). METHODS AND RESULTS:We carried out a multicentre s...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1002/ejhf.2016
更新日期：2020-10-02 00:00:00
abstract：BACKGROUND:Information about the occurrence of heart failure in the acute phase of myocardial infarction (MI) in diabetic patients and its impact on prognosis are sparse. AIM:The purpose of the present study was to describe how MI patients with diabetes mellitus (DM) differed from MI patients without DM with respect t...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/s1388-9842(00)00117-3
更新日期：2001-01-01 00:00:00
abstract：AIMS:We investigated the association between quantified metabolite, lipid and lipoprotein measures and incident heart failure hospitalisation (HFH) in the elderly, and examined whether circulating metabolic measures improve HFH prediction. METHODS AND RESULTS:Overall, 80 metabolic measures from the PROspective Study o...
journal_title：European journal of heart failure
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1002/ejhf.1076
更新日期：2018-04-01 00:00:00
abstract：AIMS:It is unclear whether myocardial velocity or deformation indices of dyssynchrony are better at predicting response to cardiac resynchronization therapy (CRT). Therefore, two indices of left ventricular (LV) dyssynchrony based on myocardial velocity and deformation were compared to predict success of CRT. METHODS ...
journal_title：European journal of heart failure
pub_type： 杂志文章,多中心研究
doi：10.1093/eurjhf/hfp032
更新日期：2009-04-01 00:00:00
abstract：:Patients with chronic coronary heart disease often suffer from congestive heart failure (CHF) despite multiple drug therapies. D-Ribose has been shown in animal models to improve cardiac energy metabolism and function following ischaemia. This was a prospective, double blind, randomized, crossover design study, to ass...
journal_title：European journal of heart failure
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s1388-9842(03)00060-6
更新日期：2003-10-01 00:00:00
abstract：AIMS:To investigate the relationship between central venous pressure (CVP) at presentation to the emergency room (ER) and the risk of cardiac rehospitalization and mortality in patients with decompensated heart failure (DHF). METHODS AND RESULTS:Central venous pressure was determined non-invasively using high-resoluti...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1093/eurjhf/hfq024
更新日期：2010-05-01 00:00:00
abstract：:COMBAT is a prospective, multicenter, randomized, blinded clinical study, with crossover design. The main objective is the comparative evaluation of atrio-biventricular versus conventional atrioventricular stimulation (atrio and right ventricle) in patients with heart failure and bradycardia as the primary indication ...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/j.ejheart.2004.06.008
更新日期：2005-03-02 00:00:00
abstract：:Patients with heart failure (HF) are at an increased risk of stroke, sudden death and venous thromboembolism, which are all linked to thrombus formation (thrombogenesis). The present 'viewpoint' article will discuss how the prothrombotic state in HF may be perpetuated by a chronic inflammatory state that is maladaptiv...
journal_title：European journal of heart failure
pub_type： 杂志文章,评审
doi：10.1016/j.ejheart.2006.05.009
更新日期：2007-02-01 00:00:00
abstract：:Heart rate not only predicts outcome but may also be a therapeutic target in patients with chronic heart failure. Several classes of pharmacological agents can be used to modulate heart rate, including beta-blockers, ivabradine, digoxin, amiodarone, and verapamil. Choice of agent will depend on heart rhythm, co-morbid...
journal_title：European journal of heart failure
pub_type： 杂志文章,评审
doi：10.1093/eurjhf/hft129
更新日期：2014-01-01 00:00:00
abstract：AIMS:Current guidelines for the diagnosis of heart failure with normal or preserved ejection fraction (HFpEF) are based on measurements at rest. However, in HFpEF ventricular dysfunction is more apparent on exercise. We hypothesized that Mitral annular plane systolic excursion (MAPSE) which is easy to acquire on exerci...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1093/eurjhf/hfr081
更新日期：2011-09-01 00:00:00
abstract：:Transthyretin amyloidosis (ATTR) is a rare, yet underdiagnosed disease characterized by progressive impairment of neurologic and cardiac function due to deposition of misfolded transthyretin. Despite great efforts, such as the introduction of orthotopic liver transplant, the devastating prognosis for both variant and ...
journal_title：European journal of heart failure
pub_type： 杂志文章,评审
doi：10.1002/ejhf.1695
更新日期：2020-01-01 00:00:00
abstract：AIMS:The most recent European guidelines have proposed new definitions of pulmonary hypertension (PH) in left heart disease, to better approach the characteristics required to reflect the presence of pulmonary vascular disease. The purpose of this study was to assess whether different haemodynamic definitions of post-c...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1002/ejhf.1067
更新日期：2018-04-01 00:00:00
abstract：AIMS:To evaluate in patients with heart failure (HF) due to systolic dysfunction the occurrence of polypharmacy, alternative medicine, immunization against influenza, and patients' knowledge about their medication. METHODS AND RESULTS:Sixty-five patients, 49 men, mean age 60.5+/-12.0 years answered a confidential ques...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/j.ejheart.2003.09.009
更新日期：2004-03-01 00:00:00
abstract：:Heart failure (HF) in elderly patients is associated with more diffuse symptoms and signs due to the presence of other noncardiac comorbidities. This can cause difficulties in assessing the correct diagnosis and initiating appropriate therapy. The four most frequently occurring noncardiac comorbidities and therapies u...
journal_title：European journal of heart failure
pub_type： 杂志文章,评审
doi：10.1016/j.ejheart.2005.01.008
更新日期：2005-03-16 00:00:00
abstract：AIMS:Randomized trials have shown that beta-blockers (BBs) reduce mortality in chronic heart failure (HF). Less data are available on the role of BBs in patients with acute HF, specifically if BBs should be continued or temporarily withdrawn. The aim of this study was to evaluate the role of BBs on in-hospital outcomes...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1093/eurjhf/hfn008
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:Cardiac resynchronization therapy (CRT) improves symptoms, left ventricular ejection fraction (LVEF) and survival in patients with heart failure and wide QRS, however, long term clinical outcome is unknown. AIMS:To identify predictors of mortality and evaluate the effects of CRT after long term follow-up. ...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/j.ejheart.2008.06.013
更新日期：2008-08-01 00:00:00
abstract：BACKGROUND:Heart failure with preserved ejection fraction (HFpEF) is a global public health problem. Unfortunately, little is known about HFpEF across Asia. METHODS AND RESULTS:We prospectively studied clinical characteristics, echocardiographic parameters and outcomes in 1204 patients with HFpEF (left ventricular eje...
journal_title：European journal of heart failure
pub_type： 杂志文章,多中心研究
doi：10.1002/ejhf.1227
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:The EURObservational Research Programme is a rolling programme of cardiovascular registries and surveys of the European Society of Cardiology (ESC). These registries will provide information on the nature of cardiovascular disease and its management. This manuscript provides an update on new literature on pe...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1002/ejhf.68
更新日期：2014-05-01 00:00:00
abstract：:Impaired cardiac function is frequently accompanied by peripheral vascular dysfunction and a pro-inflammatory condition, which may be associated with elevated levels of angiotensin II. We hypothesized that the magnitude of flow mediated dilatation (FMD) of the brachial artery of post myocardial infarction patients wil...
journal_title：European journal of heart failure
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ejheart.2005.10.011
更新日期：2006-08-01 00:00:00
abstract：AIMS:Myostatin inhibits myoblast differentiation/proliferation and may play a role in heart failure (HF) and reverse remodelling after left ventricular assist device (LVAD) support. This study sought to characterize myostatin expression and activation in advanced HF before and after LVAD support. METHODS AND RESULTS:L...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1093/eurjhf/hfq039
更新日期：2010-05-01 00:00:00
abstract：AIMS:Heart failure (HF) patients with a mid-range ejection fraction (HFmrEF) are not well characterized. Accordingly, we examined the epidemiology, pathophysiology and clinical outcomes of HF patients with a left ventricular ejection fraction (LVEF) of 40-50%. METHODS AND RESULTS:We identified 168 patients with an LVE...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1002/ejhf.879
更新日期：2017-12-01 00:00:00
abstract：AIMS:Several studies have shown that older patients with heart failure with reduced ejection fraction (HFrEF) are undertreated. The aim of this study was to evaluate the association of up-titration of angiotensin-converting enzyme inhibitors (ACEI), angiotensin receptor blockers (ARB) and beta-blockers on outcome acros...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1002/ejhf.1799
更新日期：2020-03-25 00:00:00
abstract：BACKGROUND:Myocardial contractility can be altered using voltage clamp techniques by modulating amplitude and duration of the action potential resulting in enhanced calcium entry in the cell of isolated muscle strips (Non-Excitatory Currents; NEC). Extracellular electrical stimuli delivered during the absolute refracto...
journal_title：European journal of heart failure
pub_type： 杂志文章
doi：10.1016/j.ejheart.2005.05.011
更新日期：2006-01-01 00:00:00
abstract：AIMS:Supervised exercise can benefit selected patients with heart failure, however the effectiveness of home-based exercise remains uncertain. We aimed to assess the effectiveness of a home-based exercise programme in addition to specialist heart failure nurse care. METHODS AND RESULTS:This was a randomized controlled...
journal_title：European journal of heart failure
pub_type： 杂志文章,随机对照试验
doi：10.1093/eurjhf/hfn029
更新日期：2009-02-01 00:00:00
