Dietary cadmium and risk of breast cancer subtypes defined by hormone receptor status: A prospective cohort study.

abstract：:We evaluated RS5444, a thiazolidinedione high affinity PPARgamma agonist, for the ability to inhibit colon carcinogenesis in azoxymethane (AOM)-treated mice. In our initial experiment, mice were treated with RS5444 during AOM treatment, and the drug was withdrawn 12 weeks after the last injection of AOM. RS5444 signif...

journal_title：International journal of cancer

authors： Su W,Necela BM,Fujiwara K,Kurakata S,Murray NR,Fields AP,Thompson EA

更新日期：2008-09-01 00:00:00

abstract：:We obtained Thy-I-positive cells directly from growing methylcholanthrene-induced (MCA-1510) sarcomas using fluorescence-activated cell sorting, then cultured these lymphocytes in medium containing Interleukin-2 and tested their activity in vivo against various MCA-sarcoma lines with the Winn assay. We found that cult...

journal_title：International journal of cancer

authors： Mulé JJ,Forstrom JW,George E,Hellström I,Hellström KE

更新日期：1981-11-15 00:00:00

abstract：:The ganglioside composition of 20 human malignant melanomas and 5 normal tissues (muscle, spleen, kidney, liver and brain) was analyzed by high-performance thin-layer chromatography (HPTLC) and immune HPTLC using a panel of antiganglioside monoclonal antibodies, and quantified by photodensitometry. The most prominent ...

journal_title：International journal of cancer

authors： Hamilton WB,Helling F,Lloyd KO,Livingston PO

更新日期：1993-02-20 00:00:00

abstract：:Chile's gallbladder cancer rates are among the highest in the world, being the leading cause of cancer deaths among Chilean women. To provide insights into the etiology of gallbladder cancer, we conducted an ecologic study examining the geographical variation of gallbladder cancer and several putative risk factors. Th...

journal_title：International journal of cancer

authors： Andia ME,Hsing AW,Andreotti G,Ferreccio C

更新日期：2008-09-15 00:00:00

abstract：:Galectin-1 and galectin-3 are galactoside-binding proteins involved in different steps of tumor progression and potential targets for therapy. We have investigated the expression of these galectins in 38 human bladder transitional-cell carcinomas of different histological grade and clinical stage and in 5 normal uroth...

journal_title：International journal of cancer

authors： Cindolo L,Benvenuto G,Salvatore P,Pero R,Salvatore G,Mirone V,Prezioso D,Altieri V,Bruni CB,Chiariotti L

更新日期：1999-02-19 00:00:00

abstract：:Malignant activation of oncogenes ras or trk is implicated in a number of solid tumors and leukemias. We determined the chemosensitivity profile of wild-type mouse NIH-3T3 fibroblasts, and that of NIH-3T3 lines transformed by the H-ras (S2-721) and trk (106-632) oncogenes, against 11 different drugs from various class...

journal_title：International journal of cancer

authors： Peters GJ,Wets M,Keepers YP,Oskam R,van Ark-Otte J,Noordhuis P,Smid K,Pinedo HM

更新日期：1993-05-28 00:00:00

abstract：:Previous studies have reported an association between hot tea drinking and risk of esophageal cancer, but no study has examined this association using prospectively and objectively measured tea drinking temperature. We examined the association of tea drinking temperature, measured both objectively and subjectively at ...

journal_title：International journal of cancer

authors： Islami F,Poustchi H,Pourshams A,Khoshnia M,Gharavi A,Kamangar F,Dawsey SM,Abnet CC,Brennan P,Sheikh M,Sotoudeh M,Nikmanesh A,Merat S,Etemadi A,Nasseri Moghaddam S,Pharoah PD,Ponder BA,Day NE,Jemal A,Boffetta P,Mal

更新日期：2020-01-01 00:00:00

abstract：:Many recent data indicate that some alleles encoded in the central major histocompatibility complex (MHC) region (Class III) of short arm of chromosome 6 may modify the risk of cancer development. Therefore we determined 4 single nucleotide polymorphisms (SNPs) of this region (TNF-alpha -308 G > A, RAGE -429 T > C, HS...

journal_title：International journal of cancer

authors： Tóth EK,Kocsis J,Madaras B,Bíró A,Pocsai Z,Fust G,Blaskó B,Karádi I,Adány R,Laki J

更新日期：2007-10-15 00:00:00

abstract：:A population-based case-control study of incident primary brain tumors in adults was carried out in Adelaide, Australia in the period 1987 through 1990. It included 110 subjects with newly diagnosed primary glioma, 60 subjects with meningioma and 417 controls selected from the Australian Electoral Roll and frequency-m...

journal_title：International journal of cancer

authors： Ryan P,Lee MW,North B,McMichael AJ

更新日期：1992-04-22 00:00:00

abstract：:We have used differential-display PCR (DD-PCR) to compare renal-cell carcinoma (RCC) and normal kidney gene expression with the aim of identifying genes specifically associated with RCC. Using a modified DD-PCR approach, which was non-radioactive, quicker and simpler than the conventional method, 24 cDNA samples were ...

journal_title：International journal of cancer

authors： Rae FK,Stephenson SA,Nicol DL,Clements JA

更新日期：2000-12-01 00:00:00

abstract：:Screening for cancer has to be carefully organized for maximum effectiveness, and introduced in full understanding of the natural history of the disease. There are major potential harms as well as benefits from screening. The current state of art for breast, cervix and prostate cancer screening is reviewed, only for b...

journal_title：International journal of cancer

authors： Miller AB

更新日期：2010-03-01 00:00:00

abstract：:Metastasis to the liver often occurs in patients during the natural course of pancreatic cancer. Using carcinoma cell lines established from 9 such patients, we examined phenotypes of cell lines to search for correlations with their potential to metastasize to the liver. Anti-asialo GMI-treated nude mice were used. PC...

journal_title：International journal of cancer

authors： Kishimoto T,Ishikura H,Kimura C,Takahashi T,Kato H,Yoshiki T

更新日期：1996-08-22 00:00:00

abstract：:Moderate to high-dose radiotherapy is known to increase the risk of breast cancer. Uncertainties remain about the effects of low-dose chest X-rays, particularly in individuals at increased genetic risk. We analyzed case-control data from the Breast Cancer Family Registry. Self-reported data on therapeutic and diagnost...

journal_title：International journal of cancer

authors： John EM,Phipps AI,Knight JA,Milne RL,Dite GS,Hopper JL,Andrulis IL,Southey M,Giles GG,West DW,Whittemore AS

更新日期：2007-07-15 00:00:00

abstract：:Vaccination strategies based on repeated injections of NY-ESO-1 protein formulated in ISCOMATRIX particles (NY-ESO-1 ISCOMATRIX) have shown to elicit combined NY-ESO-1 specific antibody and T cell responses. However, it remains unclear whether heterologous prime-boost strategies based on the combination with NY-ESO-1 ...

journal_title：International journal of cancer

authors： Chen JL,Dawoodji A,Tarlton A,Gnjatic S,Tajar A,Karydis I,Browning J,Pratap S,Verfaille C,Venhaus RR,Pan L,Altman DG,Cebon JS,Old LL,Nathan P,Ottensmeier C,Middleton M,Cerundolo V

更新日期：2015-03-15 00:00:00

abstract：:To assess the effect of different hospital types or surgical volume on the survival of ovarian cancer patients, a nationwide and population-based analysis was carried out in Finland. The study included all 3,851 ovarian cancer patients operated from 1983-94. The patients were classified according to the hospital of th...

journal_title：International journal of cancer

authors： Kumpulainen S,Grénman S,Kyyrönen P,Pukkala E,Sankila R

更新日期：2002-12-10 00:00:00

abstract：:A family history of stomach cancer in first-degree relatives increases the risk of stomach cancer, but uncertainties remain as concerns the variation of the risk according to age, sex and type of relative, as well as on the role of family history of other cancers. We investigated the issue using data from a multicentr...

journal_title：International journal of cancer

authors： Foschi R,Lucenteforte E,Bosetti C,Bertuccio P,Tavani A,La Vecchia C,Negri E

更新日期：2008-09-15 00:00:00

abstract：:A human papillomavirus (HPV) was cloned from a patient with multiple squamous cell carcinomas (SCCs) and identified as HPV88, recently categorized into a new species within the genus Gamma. The HPV88 viral load in an SCC of the index patient exceeded 1 million copies/cell. By contrast, a survey of 447 skin lesions (79...

journal_title：International journal of cancer

authors： Kullander J,Handisurya A,Forslund O,Geusau A,Kirnbauer R,Dillner J

更新日期：2008-01-15 00:00:00

abstract：:We used oligonucleotide microarrays to investigate gene expression changes associated with multi-step human papillomavirus type 16 (HPV16)-mediated carcinogenesis in vitro. Gene expression profiles in 4 early passage HPV16-immortalized human keratinocyte (HKc) lines derived from different donors were compared with the...

journal_title：International journal of cancer

authors： Wan F,Miao X,Quraishi I,Kennedy V,Creek KE,Pirisi L

更新日期：2008-07-01 00:00:00

abstract：:In advanced cancer patients, the oxidative stress could take place either at the onset of disease or as a function of disease progression. To test this hypothesis, the following parameters were investigated: the erythrocyte activity of the enzymes superoxide dismutase (SOD) and glutathione peroxidase (GPx), the serum ...

journal_title：International journal of cancer

authors： Mantovani G,Macciò A,Madeddu C,Mura L,Gramignano G,Lusso MR,Mulas C,Mudu MC,Murgia V,Camboni P,Massa E,Ferreli L,Contu P,Rinaldi A,Sanjust E,Atzei D,Elsener B

更新日期：2002-03-01 00:00:00

abstract：:Studies in Shanghai and in north-east China indicate that cigarette smoking is a major contributor to the high rates of lung cancer in those areas, but doubts persist regarding the influence of cigarette use on lung cancer rates in other areas of China. In addition, the risk of lung cancer associated with other method...

journal_title：International journal of cancer

authors： Lubin JH,Li JY,Xuan XZ,Cai SK,Luo QS,Yang LF,Wang JZ,Yang L,Blot WJ

更新日期：1992-05-28 00:00:00

abstract：:I-compounds are bulky indigenous DNA adducts that can be detected by (32)P-postlabeling. A subgroup, termed type II I-compounds, represents DNA lesions induced by oxidative stress. Several major type II I-compounds have been identified as dinucleotides containing 3'-terminal 8,5'-cyclo-2'-deoxyadenosine (cA). Levels o...

journal_title：International journal of cancer

authors： Zhou GD,Randerath K,Donnelly KC,Jaiswal AK

更新日期：2004-12-10 00:00:00

abstract：:Cancer-related cachexia is a metabolic syndrome characterized by a wasting disorder of adipose and skeletal muscle and is accompanied by body weight loss and systemic inflammation. The treatment options for cancer cachexia are limited, and the molecular mechanism remains poorly understood. Circular RNAs (circRNAs) are...

journal_title：International journal of cancer

authors： Zhang H,Zhu L,Bai M,Liu Y,Zhan Y,Deng T,Yang H,Sun W,Wang X,Zhu K,Fan Q,Li J,Ying G,Ba Y

更新日期：2019-05-15 00:00:00

abstract：:Alcohol consumption is associated with a modest increased risk of colon cancer, but its relationship with colon cancer survival has not been elucidated. Using data from a phase III randomized adjuvant trial, we assessed the association of alcohol consumption with colon cancer outcomes. Patients completed a risk factor...

journal_title：International journal of cancer

authors： Phipps AI,Shi Q,Limburg PJ,Nelson GD,Sargent DJ,Sinicrope FA,Chan E,Gill S,Goldberg RM,Kahlenberg M,Nair S,Shields AF,Newcomb PA,Alberts SR,Alliance for Clinical Trials in Oncology.

更新日期：2016-09-01 00:00:00

abstract：:Licensed human papillomavirus (HPV) vaccines are expected to prevent high-risk (hr) HPV-infections (most notably types 16 and 18). Whether HPV vaccination will change the distribution of hrHPVs at the population level is open, since competition between HPV types is not well understood. Two stratified random subcohorts...

journal_title：International journal of cancer

authors： Kaasila M,Koskela P,Kirnbauer R,Pukkala E,Surcel HM,Lehtinen M

更新日期：2009-11-01 00:00:00

abstract：:Thrombin is now recognized as an important factor in many cancers. Here, we examined the expression and role of the recently discovered thrombin receptor PAR4, in human colon cancer cells. PAR4 mRNA was found in 10 out of 14 (71%) human colon cancer cell lines tested but not in epithelial cells isolated from normal hu...

journal_title：International journal of cancer

authors： Gratio V,Walker F,Lehy T,Laburthe M,Darmoul D

更新日期：2009-04-01 00:00:00

abstract：:To investigate the genetic changes that occur during establishment of gastric cancer cell lines, 4 gastric cancer cell lines and their original tumor tissues were examined for microsatellite instability (MSI), loss of heterozygosity (LOH), and p53 mutation. MSI status did not change during the establishment, though th...

journal_title：International journal of cancer

authors： Bae SI,Park JG,Kim YI,Kim WH

更新日期：2000-08-15 00:00:00

abstract：:Tonsillar squamous cell carcinoma (TSCC) is frequently associated with human papillomavirus (HPV) and chromosome instability. Data from cellular model systems are, however, controversial concerning a relation between HPV and chromosome instability development. Here we studied this association in 77 primary TSCC with k...

journal_title：International journal of cancer

authors： Mooren JJ,Kremer B,Claessen SM,Voogd AC,Bot FJ,Peter Klussmann J,Huebbers CU,Hopman AH,Ramaekers FC,Speel EJ

更新日期：2013-04-15 00:00:00

abstract：:Caspase recruitment domain-containing protein 9 (CARD9) is an adaptor protein and highly expressed in myeloid cells. Our previous study demonstrates a critical protective effect of CARD9 in the development of colitis-associated colon cancer. Nevertheless, the effect of CARD9 in lung cancer remains unclear. Here, using...

journal_title：International journal of cancer

authors： Qu J,Liu L,Xu Q,Ren J,Xu Z,Dou H,Shen S,Hou Y,Mou Y,Wang T

更新日期：2019-10-15 00:00:00

abstract：:Nude athymic rats of Rowett genetic background were injected subcutaneously with cells from a poorly differentiated human pulmonary adenocarcinoma, following propagation in nude mice. The tumour cells were obtained by thoracentesis and by pleural biopsy during thoracoscopy. So far, we have heterotransplanted 13 differ...

journal_title：International journal of cancer

authors： Korsgaard R,Lindén CJ,Willén R,Willén H,Svensson G,Simonsson BG

更新日期：1983-12-15 00:00:00

abstract：:Rabbits were immunized with extracts of primary or grafted intestinal adeno-carcinomas induced by carcinogenic drugs in inbred rats. After absorption with normal tissue extracts, the antisera were able to recognize three tumor-associated antigens. Two of them were glycoproteins, present in cancer cells but also, in tr...

journal_title：International journal of cancer

authors： Martin F,Martin MS,Bordes M,Knobel S

更新日期：1975-01-15 00:00:00