Autoradiographic evidence for beta-adrenergic receptors on capsaicin-sensitive primary afferent terminals in rat spinal cord.

Abstract:

:Specific [3H]dihydroalprenolol binding sites are enriched in the dorsal grey matter of rat spinal cord. Neonatal capsaicin treatment, known to cause a permanent loss of a population of primary afferent neurones, caused a significant loss of specific [3H]dihydroalprenolol binding sites from laminae of the dorsal horn. These results suggest that capsaicin-sensitive primary afferent terminals may bear presynaptic beta-adrenergic receptors.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Patterson SI,Hanley MR

doi

10.1016/0304-3940(87)90554-4

subject

Has Abstract

pub_date

1987-07-09 00:00:00

pages

17-21

issue

1

eissn

0304-3940

issn

1872-7972

pii

0304-3940(87)90554-4

journal_volume

78

pub_type

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