The plasma membrane calcium pumps-The old and the new.

abstract：:The ability in vivo of the muscarinic agonist, pilocarpine, to increase phosphoinositol (PI) hydrolysis in lithium pretreated rats was investigated by measuring the accumulation of [(3)H]inositol phosphates (IP). As expected, 20 mg/kg s.c. pilocarpine, a muscarinic agonist, increased PI hydrolysis in the striatum, fro...

journal_title：Neuroscience letters

authors： Johnson MP,Kelly GM,Chamberlain M

更新日期：2000-05-05 00:00:00

abstract：:The Chronic Constriction Injury of the Infraorbital Nerve (CCI-ION) is a well-established model to study facial sensory changes related to trigeminal neuropathic pain. CCI-ION induces heat hypersensitivity that resolves within 2-3 weeks and a delayed mechanical hypersensitivity that emerges during the second week post...

journal_title：Neuroscience letters

authors： Nones CFM,Claudino RF,Ferreira LEN,Dos Reis RC,King T,Chichorro JG

更新日期：2017-03-22 00:00:00

abstract：:The circadian modulation of occurrence of non-rapid-eye-movement sleep (NREM) was investigated in 37 volunteers under dim-light conditions after 24-h total sleep deprivation using a 26-h 10/20-min ultra-short sleep-wake schedule. The propensity of NREM showed rapid increase followed by gradual decrease during the subj...

journal_title：Neuroscience letters

authors： Tagaya H,Uchiyama M,Shibui K,Kim K,Suzuki H,Kamei Y,Okawa M

更新日期：2002-04-19 00:00:00

abstract：:The effects of a series of chloride transport blockers (ethacrynate, furosemide, torasemide, 4,4'-diisothiocyano-2,2'-disulfonic acid stilbene and diphenylcarboxylate) on Cl(-)-dependent L-[3H]glutamate (Glu) binding were tested in rat brain membranes, Cl-transport blockers inhibit the Ca2+/Cl(-)-induced increase in L...

journal_title：Neuroscience letters

authors： Recasens M,Pin JP,Bockaert J

更新日期：1987-02-24 00:00:00

abstract：:Interleukin-1 (IL-1) mediates numerous responses on the mouse anterior pituitary cell line AtT-20. We have studied the ligand binding properties of the IL-1 receptors (IL-1R) of the AtT-20 cells and found that they possess 1.5 x 10(3) receptors/cell with a Kd of 0.15 nM for [125I]IL-1 alpha. Using oligonucleotide prim...

journal_title：Neuroscience letters

authors： Bristulf J,Simoncsits A,Bartfai T

更新日期：1991-07-22 00:00:00

abstract：:Propofol has been demonstrated as a drug of abuse in humans. Our previous study indicated that dexamethasone, a potent agonist of glucocorticoid receptor (GR), inhibited propofol-maintained rat self-administration behaviors by systematic injection. However, the direct effect of GR in the nucleus accumbens (NAc) on pro...

journal_title：Neuroscience letters

authors： Wu B,Lin W,Wang H,Abdullah T,Wang B,Su Y,Ge RS,Lian Q

更新日期：2018-01-01 00:00:00

abstract：:We compared the modulation of GABA (gamma-aminobutyric acid)-activated currents by benzodiazepines in recombinant GABAA receptors containing either one of two alpha subunits, alpha 1 or alpha 6. Lüddens et al. (Nature, 346 (1990) 648-651) have previously demonstrated that the alpha 6 subunit is part of a cerebellar re...

journal_title：Neuroscience letters

authors： Kleingoor C,Ewert M,von Blankenfeld G,Seeburg PH,Kettenmann H

更新日期：1991-09-16 00:00:00

abstract：:By means of a new photographic method to quantitate catecholamine fluorescence in tissue sections it has been possible to demonstrate a high dopamine (DA) turnover within the DA cell bodies of the midbrain. The medially located small-sized DA cell bodies of the A10 DA cell group has a very high DA turnover which was s...

journal_title：Neuroscience letters

authors： Agnati LF,Fuxe K,Andersson K,Benfenati F,Cortelli P,D'Alessandro R

更新日期：1980-05-15 00:00:00

abstract：:Reactive oxygen species (ROS), such as superoxide and hydrogen peroxide, play essential roles in physiological plasticity and are also involved in the pathogenesis of persistent pain. Roles of peripheral and spinal ROS in pain have been well established, but much less is known about ROS in the amygdala, a brain region...

journal_title：Neuroscience letters

authors： Lu YF,Neugebauer V,Chen J,Li Z

更新日期：2016-04-21 00:00:00

abstract：:Cancer patients with bone metastases often suffer breakthrough pain. However, little progress has been made in the treatment of breakthrough pain and its associated mechanism(s) in the patient with cancer due to lacking of resembling and predictive animal models. We previously have demonstrated that endothelin-1 plays...

journal_title：Neuroscience letters

authors： Tang Y,Peng H,Liao Q,Gan L,Zhang R,Huang L,Ding Z,Yang H,Yan X,Gu Y,Zang X,Huang D,Cao S

更新日期：2016-03-23 00:00:00

abstract：:The effect of 5-hydroxytryptamine on the spontaneous activity of neurons of the subthalamic nucleus was examined by recording the extracellular unitary activity in an in vitro slice preparation. The most frequent response to 5-hydroxytryptamine (84% of 57 neurons tested) was an increase (twofold of basal at 10 microM)...

journal_title：Neuroscience letters

authors： Flores G,Rosales MG,Hernández S,Sierra A,Aceves J

更新日期：1995-06-02 00:00:00

abstract：:Strengthening of synaptic connections has been proposed to underlie information storage in the brain, and experience-dependent increases in synapse number have been observed. However, the effect of these new synapses on the specific connectivity, and thus function, of a given brain area remains largely unknown. We rep...

journal_title：Neuroscience letters

authors： Federmeier KD,Kleim JA,Greenough WT

更新日期：2002-11-08 00:00:00

abstract：:In order to analyze the elementary mechanisms underlying caffeine-induced epileptiform discharges, hippocampal slices of guinea pigs were exposed to this drug. When the bath concentration of caffeine exceeded 0.2 mM, periodically occurring paroxysmal depolarizations (PD) in CA3 neurons appeared. They were accompanied ...

journal_title：Neuroscience letters

authors： Moraidis I,Bingmann D,Lehmenkühler A,Speckmann EJ

更新日期：1991-08-05 00:00:00

abstract：:Hippocampal choline acetyltransferase was reduced by 89% in rats two weeks after electrolytic lesion of the septum. The hippocampal concentrations of somatostatin (SOM)-14, SOM-28 and high-molecular-weight SOM were unaltered, suggesting that the activity of hippocampal SOM neurones is not influenced by cholinergic aff...

journal_title：Neuroscience letters

authors： Pierotti AR,Simpson J

更新日期：1986-01-30 00:00:00

abstract：:Exercise increases the expression of brain-derived neurotrophic factor (BDNF) in the hippocampus and beneficially contributes to cognitive function and is accompanied by epigenetic changes. Specifically, the activity levels of histone acetyltransferases (HATs) and histone deacetylases (HDACs) regulate histone acetylat...

journal_title：Neuroscience letters

authors： Li X,Inoue T,Hayashi M,Maejima H

更新日期：2019-07-27 00:00:00

abstract：:Probiotics participate actively in the neuropsychiatric disorders. However, their roles on ischemic stroke remain unclear. This study aims to determine whether Clostridium butyricum (C. butyricum) could attenuate cerebral ischemia/reperfusion (I/R) injury and its possible mechanisms. Male ICR mice were intragastricall...

journal_title：Neuroscience letters

authors： Sun J,Ling Z,Wang F,Chen W,Li H,Jin J,Zhang H,Pang M,Yu J,Liu J

更新日期：2016-02-02 00:00:00

abstract：:[3H]Glibenclamide, a potent ATP-sensitive K+ channel blocker, is a specific ligand for the identification of the sulfonylureas receptors which are closely related to ATP-sensitive K+ channels. In order to determine the pre- or postsynaptic localization of these receptors in the rat hippocampus, we studied the effects ...

journal_title：Neuroscience letters

authors： Tremblay E,Zini S,Ben-Ari Y

更新日期：1991-06-10 00:00:00

abstract：:Intramural ganglia of colchicine-injected cat ileum were examined immunohistochemically using antisera to substance P (SP), vasoactive intestinal polypeptide (VIP) and methionine5-enkephalin (ENK). SP- and ENK-like immunoreactive nerve cells were preferentially located in the myenteric ganglia, whereas VIP-like immuno...

journal_title：Neuroscience letters

authors： Domoto T,Gonda T,Oki M,Yanaihara N

更新日期：1984-06-01 00:00:00

abstract：:Systemic administration of nitroglycerin (NTG) consistently provokes spontaneous-like migraine attacks in migraine sufferers, and in rat it induces hyperalgesia and allodynia. In the present study we modeled migraine headache by intraperitoneal (i.p.) injection of a single dose of NTG, which produced widespread therma...

journal_title：Neuroscience letters

authors： Farajdokht F,Babri S,Karimi P,Mohaddes G

更新日期：2016-09-06 00:00:00

abstract：:Cyclophosphamide (CP) has been used as an antitumour agent or immunosuppressant clinically, though the potential biological role of CP in the central nervous system (CNS) has not been clarified. In the present study, we found that pretreatment with CP prevented neuronal cell death caused by serum deprivation in cultur...

journal_title：Neuroscience letters

authors： Kitazawa H,Numakawa T,Adachi N,Kumamaru E,Tuerxun T,Kudo M,Kunugi H

更新日期：2010-02-12 00:00:00

abstract：:Gallyas-positive, tau-negative oligodendroglial cytoplasmic inclusions are specific for multiple system atrophy, while both Gallyas- and tau-positive glial fibrillary tangles are a common feature of tau-related neurological disorders. We examined the midbrain of Parkinson's disease (PD) patients and found significant ...

journal_title：Neuroscience letters

authors： Wakabayashi K,Takahashi H

更新日期：1996-10-18 00:00:00

abstract：:Spasticity in chronic hemiparetic stroke patients has primarily been treated pharmacologically. However, there is increasing evidence that physical rehabilitation can help manage hyper-excitability of reflexes (hyperreflexia), which is a primary contributor to spasticity. In the present study, one chronic hemiparetic ...

journal_title：Neuroscience letters

authors： Hoseini N,Koceja DM,Riley ZA

更新日期：2011-10-24 00:00:00

abstract：:The objective of the present study was to determine differences in neural networks between expert and novice archers during an archery pre-performance routine period (PPR). The experiment was conducted with eight world-class competitor or Olympic medalist archers and eight novices. In the experiment, the task was to s...

journal_title：Neuroscience letters

authors： Kim J,Lee HM,Kim WJ,Park HJ,Kim SW,Moon DH,Woo M,Tennant LK

更新日期：2008-11-21 00:00:00

abstract：:Application of a GABAA (gamma-aminobutyric acid-A) receptor antagonist through a microdialysis probe into the forelimb primary motor cortex of ketamine-anesthetized rats induced electromyographic activity in the contralateral forelimb. This activity consisted of spontaneous forelimb movements with a frequency of 0.8 +...

journal_title：Neuroscience letters

authors： Castro-Alamancos MA,Borrell J

更新日期：1993-02-19 00:00:00

abstract：:It is uncertain if the several brain areas in response to presemantic picture processing are functionally homogeneous. Subjects were asked to discriminate visual stimulus pairs and event-related potentials (ERPs) were recorded from the scalp. A line-drawing picture (S1) was followed by another stimulus (S2) 600 ms lat...

journal_title：Neuroscience letters

authors： Wang Y,Tang X,Kong J,Zhuang D,Li S

更新日期：1998-12-04 00:00:00

abstract：:Spinocerebellar ataxia type 17 (SCA17) is an autosomal dominant neurodegenerative disease caused by CAG expansion in the gene encoding the TATA-binding protein (TBP). The neurological features of SCA17 are Purkinje cell loss and gliosis. We have generated SCA17 transgenic mice which recapitulate the patients' phenotyp...

journal_title：Neuroscience letters

authors： Lin CW,Fan CH,Chang YC,Hsieh-Li HM

更新日期：2020-11-01 00:00:00

abstract：:We compared cerebrospinal fluid (CSF) and serum levels, and the CSF/serum ratio of alpha-tocopherol (vitamin E), measured by HPLC, in 36 patients with multiple sclerosis (MS) and 32 matched controls. The mean CSF vitamin E levels and the CSF/serum vitamin E ratio did not differ significantly between the two study grou...

journal_title：Neuroscience letters

authors： Jiménez-Jiménez FJ,de Bustos F,Molina JA,de Andrés C,Gasalla T,Ortí-Pareja M,Zurdo M,Porta J,Castellano-Millán F,Arenas J,Enríquez de Salamanca R

更新日期：1998-06-12 00:00:00

abstract：:Application of NMDA, or agents releasing nitric oxide (NO), onto the dendrites of hippocampal granule cells increased the levels of the mRNA encoding MAP2, a cytoskeletal component induced during periods of neurite outgrowth. Furthermore, local increases in the hybridisation signal in the molecular layer, representing...

journal_title：Neuroscience letters

authors： Johnston HM,Morris BJ

更新日期：1994-08-15 00:00:00

abstract：OBJECTIVES:To determine clinical characteristics and frequency of leucine-rich repeat kinase 2 gene (LRRK2) mutations in a cohort of patients with Parkinson's disease (PD) from Argentina. BACKGROUND:Variation in the LRRK2 gene represents the most common genetic determinant of PD, only few data are available from Latin...

journal_title：Neuroscience letters

authors： Gatto EM,Parisi V,Converso DP,Poderoso JJ,Carreras MC,Martí-Massó JF,Paisán-Ruiz C

更新日期：2013-03-14 00:00:00

abstract：:The breakdown in brain ionic homeostasis during energy deprivation (anoxic depolarization [AD]) is intimately linked to neuronal injury. We studied the role of one particular route of Na+ influx, voltage-sensitive Na+ channels, in the AD induced by O2 and/or glucose deprivation. We recorded extracellular Na+ concentra...

journal_title：Neuroscience letters

authors： Fung ML,Croning MD,Haddad GG

更新日期：1999-11-05 00:00:00