Myogenin promotes myocyte fusion to balance fibre number and size.

abstract：:The insulin/IGF-1 signalling (IIS) pathway plays an important role in the regulation of larval diapause, the long-lived growth arrest state called dauer arrest, in Caenorhabditis elegans. In this nematode, 40 insulin-like peptides (ILPs) have been identified as putative ligands of the IIS pathway; however, it remains ...

journal_title：Nature communications

authors： Matsunaga Y,Honda Y,Honda S,Iwasaki T,Qadota H,Benian GM,Kawano T

更新日期：2016-02-03 00:00:00

abstract：:Quantum dots (QDs) are an excellent single-photon source that can be combined with a spin quantum memory. Many quantum technologies require increased control over the characteristics of emitted photons. A powerful approach is to trigger coherent Raman photons from QDs with a Λ energy-level system, such as the spin sin...

journal_title：Nature communications

authors： Pursley BC,Carter SG,Yakes MK,Bracker AS,Gammon D

更新日期：2018-01-09 00:00:00

abstract：:Global fish production (capture and aquaculture) has increased quickly, which has altered global flows of phosphorus (P). Here we show that in 2016, [Formula: see text] Tg P yr-1 (mean and interquartile range) was applied in aquaculture to increase fish production; while [Formula: see text] Tg P yr-1 was removed from ...

journal_title：Nature communications

authors： Huang Y,Ciais P,Goll DS,Sardans J,Peñuelas J,Cresto-Aleina F,Zhang H

更新日期：2020-01-17 00:00:00

abstract：:The functional organization of the hippocampus is distributed as a gradient along its longitudinal axis that explains its differential interaction with diverse brain systems. We show that the location of human tissue samples extracted along the longitudinal axis of the adult human hippocampus can be predicted within 2...

journal_title：Nature communications

authors： Vogel JW,La Joie R,Grothe MJ,Diaz-Papkovich A,Doyle A,Vachon-Presseau E,Lepage C,Vos de Wael R,Thomas RA,Iturria-Medina Y,Bernhardt B,Rabinovici GD,Evans AC

更新日期：2020-02-19 00:00:00

abstract：:The rice blast fungus Magnaporthe oryzae is a model for studying fungal-plant interactions. Although it produces two types of spores (microconidia and macroconidia), previous infection studies have exclusively dealt with macroconidia. Germination of microconidia has not been reported, and their role in plant infection...

journal_title：Nature communications

authors： Zhang H,Wu Z,Wang C,Li Y,Xu JR

更新日期：2014-08-01 00:00:00

abstract：:Injury and loss of oligodendrocytes can cause demyelinating diseases such as multiple sclerosis. To improve our understanding of human oligodendrocyte development, which could facilitate development of remyelination-based treatment strategies, here we describe time-course single-cell-transcriptomic analysis of develop...

journal_title：Nature communications

authors： Chamling X,Kallman A,Fang W,Berlinicke CA,Mertz JL,Devkota P,Pantoja IEM,Smith MD,Ji Z,Chang C,Kaushik A,Chen L,Whartenby KA,Calabresi PA,Mao HQ,Ji H,Wang TH,Zack DJ

更新日期：2021-01-28 00:00:00

abstract：:Amongst the many spectacular properties of hybrid lead halide perovskites, their defect tolerance is regarded as the key enabler for a spectrum of high-performance optoelectronic devices that propel perovskites to prominence. However, the plateauing efficiency enhancement of perovskite devices calls into question the ...

journal_title：Nature communications

authors： Righetto M,Lim SS,Giovanni D,Lim JWM,Zhang Q,Ramesh S,Tay YKE,Sum TC

更新日期：2020-06-01 00:00:00

abstract：:Activation of the Hippo pathway effector Yap underlies many liver cancers, however no germline or somatic mutations have been identified. Autophagy maintains essential metabolic functions of the liver, and autophagy-deficient murine models develop benign adenomas and hepatomegaly, which have been attributed to activat...

journal_title：Nature communications

authors： Lee YA,Noon LA,Akat KM,Ybanez MD,Lee TF,Berres ML,Fujiwara N,Goossens N,Chou HI,Parvin-Nejad FP,Khambu B,Kramer EGM,Gordon R,Pfleger C,Germain D,John GR,Campbell KN,Yue Z,Yin XM,Cuervo AM,Czaja MJ,Fiel MI,Hosh

更新日期：2018-11-23 00:00:00

abstract：:Arctic warming can influence tundra ecosystem function with consequences for climate feedbacks, wildlife and human communities. Yet ecological change across the Arctic tundra biome remains poorly quantified due to field measurement limitations and reliance on coarse-resolution satellite data. Here, we assess decadal c...

journal_title：Nature communications

authors： Berner LT,Massey R,Jantz P,Forbes BC,Macias-Fauria M,Myers-Smith I,Kumpula T,Gauthier G,Andreu-Hayles L,Gaglioti BV,Burns P,Zetterberg P,D'Arrigo R,Goetz SJ

更新日期：2020-09-22 00:00:00

abstract：:Clustering of the T-cell receptor (TCR) is thought to initiate downstream signalling. However, the detection of protein clustering with high spatial and temporal resolution remains challenging. Here we establish a Förster resonance energy transfer (FRET) sensor, named CliF, which reports intermolecular associations of...

journal_title：Nature communications

authors： Ma Y,Pandzic E,Nicovich PR,Yamamoto Y,Kwiatek J,Pageon SV,Benda A,Rossy J,Gaus K

更新日期：2017-04-28 00:00:00

abstract：:While distinct stages of natural killer (NK) cell development have been defined, the molecular interactions that shape human NK cell maturation are poorly understood. Here we define intercellular interactions between developing NK cells and stromal cells which, through contact-dependent mechanisms, promote the generat...

journal_title：Nature communications

authors： Mace EM,Gunesch JT,Dixon A,Orange JS

更新日期：2016-07-20 00:00:00

abstract：:A platform for highly parallel direct sequencing of native RNA strands was recently described by Oxford Nanopore Technologies, but despite initial efforts it remains crucial to further investigate the technology for quantification of complex transcriptomes. Here we undertake native RNA sequencing of polyA + RNA from t...

journal_title：Nature communications

authors： Soneson C,Yao Y,Bratus-Neuenschwander A,Patrignani A,Robinson MD,Hussain S

更新日期：2019-07-31 00:00:00

abstract：:In recent years, there has been marked increase in research aimed to introduce alkali vapours into guided-wave configurations. Owing to the significant reduction in device dimensions, the increase in density of states, the interaction with surfaces and primarily the high intensities carried along the structure, a plet...

journal_title：Nature communications

authors： Stern L,Desiatov B,Mazurski N,Levy U

更新日期：2017-02-09 00:00:00

abstract：:Specialized cells in the medial entorhinal cortex (mEC), such as speed cells, head direction (HD) cells, and grid cells, are thought to support spatial navigation. To determine whether these computations are dependent on local circuits, we record neuronal activity in mEC layers II and III and optogenetically perturb l...

journal_title：Nature communications

authors： Zutshi I,Fu ML,Lilascharoen V,Leutgeb JK,Lim BK,Leutgeb S

更新日期：2018-09-12 00:00:00

abstract：:Non-aromatic nitrogen- and oxygen-containing heterocycles such as piperidines and pyrans are prevalent components of natural products and pharmaceutical drugs. Although it has been a workhorse as a synthetic method for assembling unsaturated sp(2)-hybridized substrates, transition metal-catalysed cross-coupling chemis...

journal_title：Nature communications

authors： Ding J,Rybak T,Hall DG

更新日期：2014-11-18 00:00:00

abstract：:Amazonian Dark Earths (ADEs) are unusually fertile soils characterised by elevated concentrations of microscopic charcoal particles, which confer their distinctive colouration. Frequent occurrences of pre-Columbian artefacts at ADE sites led to their ubiquitous classification as Anthrosols (soils of anthropic origin)....

journal_title：Nature communications

authors： Silva LCR,Corrêa RS,Wright JL,Bomfim B,Hendricks L,Gavin DG,Muniz AW,Martins GC,Motta ACV,Barbosa JZ,Melo VF,Young SD,Broadley MR,Santos RV

更新日期：2021-01-04 00:00:00

abstract：:Metals and polymers are dissimilar materials in terms of their physicochemical properties, but complementary in terms of functionality. As a result, metal-organic structures can introduce a wealth of novel applications in small-scale robotics. However, current fabrication techniques are unable to process three-dimensi...

journal_title：Nature communications

authors： Alcântara CCJ,Landers FC,Kim S,De Marco C,Ahmed D,Nelson BJ,Pané S

更新日期：2020-11-24 00:00:00

abstract：:Rearrangement reactions have attracted considerable interest over the past decades due to their high bond-forming efficiency and atom economy in the construction of complex organic architectures. In contrast to the well-established [3,3]-rearrangement, [1,3] O-to-C rearrangement has been far less vigorously investigat...

journal_title：Nature communications

authors： Zhou B,Zhang YQ,Zhang K,Yang MY,Chen YB,Li Y,Peng Q,Zhu SF,Zhou QL,Ye LW

更新日期：2019-07-19 00:00:00

abstract：:Multi-layer structure of functional materials often involves the integration of different crystalline phases. The film growth orientation thus frequently exhibits a transformation, owing to multiple possibilities caused by incompatible in-plane structural symmetry. Nevertheless, the detailed mechanism of the transform...

journal_title：Nature communications

authors： Zhou H,Wu L,Wang HQ,Zheng JC,Zhang L,Kisslinger K,Li Y,Wang Z,Cheng H,Ke S,Li Y,Kang J,Zhu Y

更新日期：2017-11-14 00:00:00

abstract：:The maturation of HIV-1 viral particles is essential for viral infectivity. During maturation, many copies of the capsid protein (CA) self-assemble into a capsid shell to enclose the viral RNA. The mechanistic details of the initiation and early stages of capsid assembly remain to be delineated. We present coarse-grai...

journal_title：Nature communications

authors： Grime JMA,Dama JF,Ganser-Pornillos BK,Woodward CL,Jensen GJ,Yeager M,Voth GA

更新日期：2016-05-13 00:00:00

abstract：:Complex behaviours may be viewed as sequences of modular actions, each elicited by specific sensory cues in their characteristic timescales. From this perspective, we can construct models in which unitary behavioural modules are hierarchically placed in context of related actions. Here, we analyse antennal positioning...

journal_title：Nature communications

authors： Natesan D,Saxena N,Ekeberg Ö,Sane SP

更新日期：2019-12-06 00:00:00

abstract：:Successive cold winters of severely low temperatures in recent years have had critical social and economic impacts on the mid-latitude continents in the Northern Hemisphere. Although these cold winters are thought to be partly driven by dramatic losses of Arctic sea-ice, the mechanism that links sea-ice loss to cold w...

journal_title：Nature communications

authors： Kim BM,Son SW,Min SK,Jeong JH,Kim SJ,Zhang X,Shim T,Yoon JH

更新日期：2014-09-02 00:00:00

abstract：:Culture (behaviour based on socially transmitted information) is present in diverse animal species, yet how it interacts with genetic evolution remains largely unexplored. Here, we review the evidence for gene-culture coevolution in animals, especially birds, cetaceans and primates. We describe how culture can relax o...

journal_title：Nature communications

authors： Whitehead H,Laland KN,Rendell L,Thorogood R,Whiten A

更新日期：2019-06-03 00:00:00

abstract：:Endogenous opioid peptides and prescription opioid drugs modulate pain, anxiety and stress by activating opioid receptors, currently classified into four subtypes. Here we demonstrate that ACKR3/CXCR7, hitherto known as an atypical scavenger receptor for chemokines, is a broad-spectrum scavenger of opioid peptides. Ph...

journal_title：Nature communications

authors： Meyrath M,Szpakowska M,Zeiner J,Massotte L,Merz MP,Benkel T,Simon K,Ohnmacht J,Turner JD,Krüger R,Seutin V,Ollert M,Kostenis E,Chevigné A

更新日期：2020-06-19 00:00:00

abstract：:Despite rapid advances in genome engineering technologies, inserting genes into precise locations in the human genome remains an outstanding problem. It has been suggested that site-specific recombinases can be adapted towards use as transgene delivery vectors. The specificity of recombinases can be altered either wit...

journal_title：Nature communications

authors： Eroshenko N,Church GM

更新日期：2013-01-01 00:00:00

abstract：:Modulation of CD8 coreceptor levels can profoundly affect T-cell sensitivity to antigen. Here we show that the heritable downregulation of CD8 during type 2 polarization of murine CD8(+) effector T cells in vitro and in vivo is associated with CpG methylation of several regions of the Cd8a locus. These epigenetic modi...

journal_title：Nature communications

authors： Harland KL,Day EB,Apte SH,Russ BE,Doherty PC,Turner SJ,Kelso A

更新日期：2014-03-28 00:00:00

abstract：:Marine reserves are viewed as flagship tools to protect exploited species and to contribute to the effective management of coastal fisheries. Yet, the extent to which marine reserves are globally interconnected and able to effectively seed areas, where fisheries are most critical for food and livelihood security is la...

journal_title：Nature communications

authors： Andrello M,Guilhaumon F,Albouy C,Parravicini V,Scholtens J,Verley P,Barange M,Sumaila UR,Manel S,Mouillot D

更新日期：2017-07-10 00:00:00

abstract：:Normal epithelial cells are stably connected to each other via the apical junctional complex (AJC). AJCs, however, tend to be disrupted during tumor progression, and this process is implicated in cancer dissemination. Here, using colon carcinoma cells that fail to form AJCs, we investigated molecular defects behind th...

journal_title：Nature communications

authors： Ito S,Okuda S,Abe M,Fujimoto M,Onuki T,Nishimura T,Takeichi M

更新日期：2017-11-28 00:00:00

abstract：:CDKL5 deficiency disorder (CDD) is characterized by epilepsy, intellectual disability, and autistic features, and CDKL5-deficient mice exhibit a constellation of behavioral phenotypes reminiscent of the human disorder. We previously found that CDKL5 dysfunction in forebrain glutamatergic neurons results in deficits in...

journal_title：Nature communications

authors： Tang S,Terzic B,Wang IJ,Sarmiento N,Sizov K,Cui Y,Takano H,Marsh ED,Zhou Z,Coulter DA

更新日期：2019-06-14 00:00:00

abstract：:Overcoming the restricted axonal regenerative ability that limits functional repair following a central nervous system injury remains a challenge. Here we report a regenerative paradigm that we call enriched conditioning, which combines environmental enrichment (EE) followed by a conditioning sciatic nerve axotomy tha...

journal_title：Nature communications

authors： De Virgiliis F,Hutson TH,Palmisano I,Amachree S,Miao J,Zhou L,Todorova R,Thompson R,Danzi MC,Lemmon VP,Bixby JL,Wittig I,Shah AM,Di Giovanni S

更新日期：2020-12-21 00:00:00