Retraction Note: Impact of different promoters, promoter mutation, and an enhancer on recombinant protein expression in CHO cells.

abstract：:Tumour-associated macrophages mainly comprise immunosuppressive M2 phenotypes that promote tumour progression besides anti-tumoural M1 subsets. Selective depletion or reprogramming of M2 may represent an innovative anti-cancer strategy. The actin cytoskeleton is central for cellular homeostasis and is targeted for ant...

journal_title：Scientific reports

authors： Pergola C,Schubert K,Pace S,Ziereisen J,Nikels F,Scherer O,Hüttel S,Zahler S,Vollmar AM,Weinigel C,Rummler S,Müller R,Raasch M,Mosig A,Koeberle A,Werz O

更新日期：2017-01-30 00:00:00

abstract：:Applications of biomaterials in cancer therapy has been limited to drug delivery systems and markers in radiation therapy. In this article, we introduce the concept of phase-functionalization of silicon to preferentially select cancer cell populations for survival in a catalyst and additive free approach. Silicon is p...

journal_title：Scientific reports

authors： Premnath P,Venkatakrishnan K,Tan B

更新日期：2015-06-04 00:00:00

abstract：:In the jejunum, PepT1 is particularly enriched in the well-differentiated absorptive epithelial cells in the villi. Studies of expression and function of PepT1 along the crypt-villus axis demonstrated that this protein is crucial to the process of di/tripeptide absorption. We recently exhibited that PepT1 plays an imp...

journal_title：Scientific reports

authors： Zhang Y,Viennois E,Zhang M,Xiao B,Han MK,Walter L,Garg P,Merlin D

更新日期：2016-06-01 00:00:00

abstract：:Dengue is a mild flu-like arboviral illness caused by dengue virus (DENV) that occurs in tropical and subtropical countries. An increasing number of reports have been indicating that dengue is also associated to neurological manifestations, however, little is known regarding the neuropathogenesis of the disease. Here,...

journal_title：Scientific reports

authors： Salomão NG,Rabelo K,Póvoa TF,Alves AMB,da Costa SM,Gonçalves AJS,Amorim JF,Azevedo AS,Nunes PCG,Basílio-de-Oliveira CA,Basílio-de-Oliveira RP,Geraldo LHM,Fonseca CG,Lima FRS,Mohana-Borges R,Silva EM,Dos Santos FB,Olivei

更新日期：2018-06-27 00:00:00

abstract：:A total of 185 cases (150 retrospectively and 35 prospectively) of malignant liver masses were collected. In the retrospectively collected cases hyperenhancement during wash-in was the most common feature in HCCs but there was a high percentage of cases showing no enhancement or hypo/isoenhancement. ICCs displayed a l...

journal_title：Scientific reports

authors： Burti S,Zotti A,Rubini G,Orlandi R,Bargellini P,Bonsembiante F,Banzato T

更新日期：2020-04-08 00:00:00

abstract：:In the present study rice straw (R, control) was mixed with Cowdung (C), Azolla (A) and cellulolytic fungus Aspergillus terreus (F) in different combinations viz. RC, RA, RF, RCF, RCA, RFA and RCFA and subjected to aerobic composting (Acom) and vermicomposting (Vcom - with Eisenia fetida). It was found that addition o...

journal_title：Scientific reports

authors： Arora M,Kaur A

更新日期：2019-02-04 00:00:00

abstract：:Affinity maturation is one of the cardinal strategies for improving antibody function using in vitro evolutionary methods; one such well-established method is phage display. To minimise gene deletion, we previously developed an open sandwich (OS) method wherein selection was performed using only phage-displaying VH fr...

journal_title：Scientific reports

authors： Sanada H,Kobayashi K,Oyama K,Maru T,Nakanishi T,Umetsu M,Asano R,Kumagai I

更新日期：2018-04-03 00:00:00

abstract：:Caspase-3-related DEVDase activity is initiated upon apoptosis in unfertilized starfish eggs. In this study, we cloned a starfish procaspase-3 corresponding to mammalian effector caspase containing a CARD that is similar to the amino terminal CARD of mammalian capsase-9, and we named it procaspase-3/9. Recombinant pro...

journal_title：Scientific reports

authors： Tamura R,Takada M,Sakaue M,Yoshida A,Ohi S,Hirano K,Hayakawa T,Hirohashi N,Yura K,Chiba K

更新日期：2018-01-25 00:00:00

abstract：:We report, for the first time, the generation of high-order harmonics in a spectral range between 200 eV and 1 keV with an unusual spectral property: only every 4(th) (4i + 1, i∈ℵ) harmonic line appears, whereas the usual high-harmonic spectra consist of every odd (2i + 1) harmonic. We attribute this unique property t...

journal_title：Scientific reports

authors： Seres J,Seres E,Landgraf B,Ecker B,Aurand B,Kuehl T,Spielmann C

更新日期：2014-02-28 00:00:00

abstract：:The presence of non-poplar extracts, cutin, and wax layer in the wheat straw outer surface (WOS) greatly limit its application in bio-composite preparation. In this study, a dielectric-barrier-discharge plasma using water vapor as feeding gas was used to fast modify the WOS. The morphology, free radical concentrations...

journal_title：Scientific reports

authors： Chen W,Xu Y,Shi S,Cao Y,Chen M,Zhou X

更新日期：2018-02-02 00:00:00

abstract：:The use of entomopathogenic fungi for biocontrol of plant pests is recently receiving an increased interest due to the need of reducing the impact of agricultural practices on the environment. Biocontrol efficacy could be improved by co-inoculation of different microorganisms. However, interactions between the fungal ...

journal_title：Scientific reports

authors： Canfora L,Abu-Samra N,Tartanus M,Łabanowska BH,Benedetti A,Pinzari F,Malusà E

更新日期：2017-10-12 00:00:00

abstract：:The aim of this study was to investigate whether a novel physiologically relevant marker, InsuTAG (fasting insulin × fasting triglycerides) can predict insulin resistance (IR) and metabolic syndrome (MetS). Data of 618 participants from the Retirement Health and Lifestyle Study (RHLS) were evaluated for the current st...

journal_title：Scientific reports

authors： Thota RN,Abbott KA,Ferguson JJA,Veysey M,Lucock M,Niblett S,King K,Garg ML

更新日期：2017-11-09 00:00:00

abstract：:One strategy to address new potential dangers is to generate defensive responses to stimuli that remind learned threats, a phenomenon called fear generalization. During a threatening experience, the brain encodes implicit and explicit memory traces. Nevertheless, there is a lack of studies comparing implicit and expli...

journal_title：Scientific reports

authors： Manassero E,Mana L,Concina G,Renna A,Sacchetti B

更新日期：2019-09-16 00:00:00

abstract：:There are few studies examining the association between homocysteine (Hcy) level and the risk of hypertension with consideration for folate and vitamin B12 as related to Hcy level. We simultaneously examined the associations of plasma levels of Hcy, folate, and vitamin B12, and dietary folate intake with the prevalenc...

journal_title：Scientific reports

authors： Tamura T,Kuriyama N,Koyama T,Ozaki E,Matsui D,Kadomatsu Y,Tsukamoto M,Kubo Y,Okada R,Hishida A,Sasakabe T,Kawai S,Naito M,Takashima N,Kadota A,Tanaka K,Hara M,Suzuki S,Nakagawa-Senda H,Takezaki T,Shimoshikiryo I,

更新日期：2020-10-28 00:00:00

abstract：:Traditional risk assessment and source apportionment of sediments based on bulk polycyclic aromatic hydrocarbons (PAHs) can introduce biases due to unknown aging effects in various sediments. We used a mild solvent (hydroxypropyl-β-cyclodextrin) to extract the bioavailable fraction of PAHs (a-PAHs) from sediment sampl...

journal_title：Scientific reports

authors： Yang X,Yu L,Chen Z,Xu M

更新日期：2016-03-15 00:00:00

abstract：:Very little is known about how fimbriae of Bacteroidetes bacteria are assembled. To shed more light on this process, we solved the crystal structures of the shaft protein Mfa1, the regulatory protein Mfa2, and the tip protein Mfa3 from the periodontal pathogen Porphyromonas gingivalis. Together these build up part of ...

journal_title：Scientific reports

authors： Hall M,Hasegawa Y,Yoshimura F,Persson K

更新日期：2018-01-29 00:00:00

abstract：:We used swept-source (SS) optical coherence tomography (OCT) and OCT angiography (OCTA) to investigate the effects of moderate physical exercise on retinal and choroidal vessel densities (VDs) and thicknesses in children. One eye in each of 40 myopic children (mean age, 11.70 years) and 18 emmetropic children (mean ag...

journal_title：Scientific reports

authors： Li S,Pan Y,Xu J,Li X,Spiegel DP,Bao J,Chen H

更新日期：2021-01-21 00:00:00

abstract：:EndMT has an important effect on metastasis and progression of tumor. This work will elucidate the effect of miR-494 on EndMT and development of HCC. Therefore, the differential miRNA expression among non-tumorous, para-tumorous and tumorous tissues was analyzed. Moreover, luciferase activities of SIRT3 3'UTR treated ...

journal_title：Scientific reports

authors： Zhang J,Zhu Y,Hu L,Yan F,Chen J

更新日期：2019-05-10 00:00:00

abstract：:Microactuators are the most distinctive and challenging microdevices among micro electromechanical systems (MEMS) relative to microsensors or electronic circuits. Soft and flexible microactuators have been achieved by introducing polymers as structural materials in addition to conventional materials. Expanding the app...

journal_title：Scientific reports

authors： Konishi S,Oya F

更新日期：2019-10-09 00:00:00

abstract：:Aberrant regulation of BCL-2 family members enables evasion of apoptosis and tumor resistance to chemotherapy. BCL-2 and functionally redundant counterpart, MCL-1, are frequently over-expressed in high-risk diffuse large B-cell lymphoma (DLBCL). While clinical inhibition of BCL-2 has been achieved with the BH3 mimetic...

journal_title：Scientific reports

authors： Dey J,Deckwerth TL,Kerwin WS,Casalini JR,Merrell AJ,Grenley MO,Burns C,Ditzler SH,Dixon CP,Beirne E,Gillespie KC,Kleinman EF,Klinghoffer RA

更新日期：2017-12-21 00:00:00

abstract：:We report on angle-dependent measurements of the sheet resistances and Hall coefficients of electron liquids in SmTiO3/SrTiO3/SmTiO3 quantum well structures, which were grown by molecular beam epitaxy on (001) DyScO3. We compare their transport properties with those of similar structures grown on LSAT [(La0.3Sr0.7)(Al...

journal_title：Scientific reports

authors： Marshall PB,Kim H,Stemmer S

更新日期：2017-09-04 00:00:00

abstract：:An optimization method to reconstruct the object profile is performed by using a flexible laser plane and bi-planar references. The bi-planar references are considered as flexible benchmarks to realize the transforms among two world coordinate systems on the bi-planar references, the camera coordinate system and the i...

journal_title：Scientific reports

authors： Xu G,Yuan J,Li X,Su J

更新日期：2018-01-24 00:00:00

abstract：:Memristors, memcapacitors, and meminductors represent an innovative generation of circuit elements whose properties depend on the state and history of the system. The hysteretic behavior of one of their constituent variables, is their distinctive fingerprint. This feature endows them with the ability to store and proc...

journal_title：Scientific reports

authors： Guarcello C,Solinas P,Di Ventra M,Giazotto F

更新日期：2017-04-24 00:00:00

abstract：:Human adenoviruses (HAdVs) shut down host cellular cap-dependent mRNA translation while initiating the translation of viral late mRNAs in a cap-independent manner. HAdV 5' untranslated regions (5'UTRs) are crucial for cap-independent initiation, and influence mRNA localization and stability. However, HAdV translationa...

journal_title：Scientific reports

authors： Ramke M,Lee JY,Dyer DW,Seto D,Rajaiya J,Chodosh J

更新日期：2017-04-04 00:00:00

abstract：:Tissue ischemia results in an accumulation of lactate and local or systemic lactic acidosis. In nociceptive sensory neurons, lactate was reported to sensitize or activate the transient receptor potential ion channel TRPA1 and acid-sensing ion channels (ASICs). However, it is unclear how lactate modulates the TRPV1 reg...

journal_title：Scientific reports

authors： de la Roche J,Walther I,Leonow W,Hage A,Eberhardt M,Fischer M,Reeh PW,Sauer S,Leffler A

更新日期：2016-11-09 00:00:00

abstract：:Many animals use sounds produced by conspecifics for mate identification. Female insects and anuran amphibians, for instance, use acoustic cues to localize, orient toward and approach conspecific males prior to mating. Here we present a novel technique that utilizes multiple, distributed sound-indication devices and a...

journal_title：Scientific reports

authors： Aihara I,Bishop PJ,Ohmer MEB,Awano H,Mizumoto T,Okuno HG,Narins PM,Hero JM

更新日期：2017-09-05 00:00:00

abstract：:The microRNA (miR)-183/96/182 cluster plays important roles in the development and functions of sensory organs, including the inner ear. Point-mutations in the seed sequence of miR-96 result in non-syndromic hearing loss in both mice and humans. However, the lack of a functionally null mutant has hampered the evaluati...

journal_title：Scientific reports

authors： Geng R,Furness DN,Muraleedharan CK,Zhang J,Dabdoub A,Lin V,Xu S

更新日期：2018-12-21 00:00:00

abstract：:Leishmaniases are an ensemble of diseases caused by the protozoan parasite of the genus Leishmania. Current antileishmanial treatments are limited and present main issues of toxicity and drug resistance emergence. Therefore, the generation of new inhibitors specifically directed against a leishmanial target is an attr...

journal_title：Scientific reports

authors： Mao W,Daligaux P,Lazar N,Ha-Duong T,Cavé C,van Tilbeurgh H,Loiseau PM,Pomel S

更新日期：2017-04-07 00:00:00

abstract：:The Toarcian Oceanic Anoxic Event (TOAE, Early Jurassic, ~182 Ma ago) was characterised by severe environmental perturbations which led to habitat degradation and extinction of marine species. Warming-induced anoxia is usually identified as main driver, but because marine life was also affected in oxygenated environme...

journal_title：Scientific reports

authors： Piazza V,Ullmann CV,Aberhan M

更新日期：2020-03-13 00:00:00

abstract：:Risk of malaria in infants can be influenced by prenatal factors. In this study, the potential for placental parasitemia at delivery in predicting susceptibility of infants to Plasmodium falciparum (Pf) infections was evaluated. Seventy-two newborns of mothers who were placental malaria negative (PM-) and of mothers w...

journal_title：Scientific reports

authors： Tassi Yunga S,Fouda GG,Sama G,Ngu JB,Leke RGF,Taylor DW

更新日期：2018-01-09 00:00:00