当前位置： SCI文献检索 > RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY期刊下所有文献 > Integration of hindbrain and carotid body mechanisms that control the autonomic response to cardiorespiratory and glucoprivic insults.

Integration of hindbrain and carotid body mechanisms that control the autonomic response to cardiorespiratory and glucoprivic insults.

Abstract：

:Autonomic reflex responses are critical in restoring changes to circulatory factors reduced beyond the domain of homeostasis. Intermittent hypoxia triggers repeated activation of chemoreflexes, resulting in baroreflex dysfunction and widespread changes in cellular and neuronal activity regulated by sensory/motor pathways. Hypoglycaemia initiates a rapid neurally-mediated counter-regulatory response. This counter-regulatory response to hypoglycaemia increases plasma adrenaline levels, liver glycogenolysis, and thus blood glucose levels. Context-dependent activation of rostral ventral medullary neurons initiates baroreceptor unloading, peripheral chemoreflex firing and the counter-regulatory response to hypoglycaemia. In this review, we briefly focus on the functional integration between peripheral and medullary pathways comprising the sympathetic baroreflex, chemoreflexes, and the counter-regulatory response to hypoglycaemia.

journal_name

Respir Physiol Neurobiol

journal_title

Respiratory physiology & neurobiology

authors

Kakall ZM,Cohen EM,Farnham MMJ,Kim SJ,Nedoboy PE,Pilowsky PM

doi

10.1016/j.resp.2018.08.008

subject

Has Abstract

pub_date

2019-07-01 00:00:00

pages

83-91

eissn

1569-9048

issn

1878-1519

pii

S1569-9048(18)30054-5

journal_volume

265

pub_type

杂志文章,评审

相关文献

RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY文献大全
  • Hypocapnia during hypoxic exercise and its impact on cerebral oxygenation, ventilation and maximal whole body O₂ uptake.

    abstract：:With hypoxic exposure ventilation is elevated through the hypoxic ventilatory response. We tested the hypothesis that the resulting hypocapnia reduces maximal exercise capacity by decreasing (i) cerebral blood flow and oxygenation and (ii) the ventilatory drive. Eight subjects performed two incremental exercise tests ...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2012.08.012

    authors： Siebenmann C,Sørensen H,Jacobs RA,Haider T,Rasmussen P,Lundby C

    更新日期：2013-01-15 00:00:00

  • Plasticity of respiratory structures--adaptive remodeling of fish gills induced by ambient oxygen and temperature.

    abstract：:While a large surface area combined with short diffusion distances make fish gills well suited for gas exchange, these properties leads to costly water and ion fluxes and exposure to toxic substances and pathogens. Thus, gill morphology is likely to be a compromise between opposing demands. It has become clear that so...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.resp.2006.02.006

    authors： Sollid J,Nilsson GE

    更新日期：2006-11-01 00:00:00

  • Interaction of tobacco smoke exposure and ovalbumin-sensitization promotes goblet cell and submucosal gland metaplasia in guinea pigs.

    abstract：:Exposure to irritants such as tobacco smoke (TS) causes acute airway inflammation. Chronic exposure may cause airway remodeling contributing to enhanced airway resistance. We hypothesize that combining airway sensitization and inhalation of irritants enhances the number of mucous producing cells beyond either agent al...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2013.07.019

    authors： Pavuluri S,Hanus V,Bergren DR

    更新日期：2013-12-01 00:00:00

  • Different respiratory behaviors disclosed by induced bronchoconstriction in mild asthma patients.

    abstract：:Respiratory responses to bronchoconstriction in asthma have been partially assessed and their significance is unclear. In 44 mild asthma patients we investigated respiratory responses during increasing levels of methacholine-induced bronchoconstriction. Inspiratory muscle activity, tidal volume, inspiratory and expira...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2013.08.013

    authors： Lavorini F,Magni C,Chellini E,Camiciottoli G,Pistolesi M,Fontana GA

    更新日期：2013-12-01 00:00:00

  • Sleep-disordered breathing: effects on brain structure and function.

    abstract：:Sleep-disordered breathing is accompanied by neural injury that affects a wide range of physiological systems which include processes for sensing chemoreception and airflow, driving respiratory musculature, timing circuitry for coordination of breathing patterning, and integration of blood pressure mechanisms with res...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.resp.2013.04.021

    authors： Harper RM,Kumar R,Ogren JA,Macey PM

    更新日期：2013-09-15 00:00:00

  • Evolution of bubbles from gas micronuclei formed on the luminal aspect of ovine large blood vessels.

    abstract：:It has been shown that tiny gas nanobubbles form spontaneously on a smooth hydrophobic surface submerged in water. These nanobubbles were shown to be the source of gas micronuclei from which bubbles evolved during decompression of silicon wafers. We suggest that the hydrophobic inner surface of blood vessels may be a ...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2013.04.013

    authors： Arieli R,Marmur A

    更新日期：2013-08-01 00:00:00

  • Ventilation-perfusion relationships in pulmonary arterial hypertension: effect of intravenous and inhaled prostacyclin treatment.

    abstract：UNLABELLED:In seven patients with idiopathic or secondary pulmonary arterial hypertension (PAH), ventilation-perfusion (V (A)/Q ) relationships were measured during a right heart catheterization using the multiple inert-gas elimination technique before and during intravenous infusion with epoprostenol (EPO), and follow...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2007.03.003

    authors： Bratel T,Lagerstrand L,Brodin LA,Nowak J,Randmaa I

    更新日期：2007-08-15 00:00:00

  • Circadian dependence of receptors that mediate wake-related excitatory drive to hypoglossal motoneurons.

    abstract：:Serotonin (5-HT), norepinephrine and orexins (ORX) are the three best established mediators of wake-related activation of hypoglossal (XII) motoneurons that innervate the muscles of the tongue. Since the tongue's use is temporarily closely aligned with the rest-activity cycle, we tested whether expression of mRNA for ...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2013.04.024

    authors： Volgin DV,Stettner GM,Kubin L

    更新日期：2013-09-15 00:00:00

  • Effect of hypoxia on expiratory muscle activity in fetal sheep.

    abstract：:The fetal respiratory response to acute hypoxia is characterized by depression, often to apnea. This study examined the effect of hypoxia on the electromyogram (EMG) of the thyroarytenoid (TA) muscle. Under anesthesia catheters were placed in the fetal sheep carotid artery, fourth cerebral ventricle, trachea and amnio...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2010.03.003

    authors： Bissonnette JM,Hohimer AR,Knopp SJ

    更新日期：2010-04-30 00:00:00

  • Histaminergic and dopaminergic traits in the human carotid body.

    abstract：:Carotid body (CB) chemoreceptors are the main sensors detecting systemic hypoxia. Studies in animals revealed that dopamine and histamine may serve as transmitters between the chemoreceptor cells and the afferent nerve. To gain insight whether histamine and dopamine could play a role in the human CB and thus be import...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2008.10.016

    authors： Lazarov NE,Reindl S,Fischer F,Gratzl M

    更新日期：2009-02-28 00:00:00

  • Functional genomics of sleep.

    abstract：:Functional genomics is a systematic and high-throughput effort to analyze the functions of genes and gene products. Functional genomics is divided into gene- and phenotype-driven approaches. Gene-driven approaches to the functional genomics of sleep have demonstrated that transcripts of many genes change as a function...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章,评审

    doi：10.1016/s1569-9048(03)00045-4

    authors： Mackiewicz M,Pack AI

    更新日期：2003-05-30 00:00:00

  • Effects of different forms of dyspnoea on pain perception induced by cold-pressor test.

    abstract：:Although dyspnoea has been shown to attenuate pain, whether different forms of dyspnoea exert a similar inhibitory effect on pain has never been tested. We examined the effects of two different forms of dyspnoea, i.e., "air hunger" sensation (AIR HUNGER) and "work/effort" sensation (WORK/EFFORT), on pain induced by a ...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2011.05.013

    authors： Yashiro E,Nozaki-Taguchi N,Isono S,Nishino T

    更新日期：2011-08-15 00:00:00

  • Effect of chronic heart failure in older rats on respiratory muscle and hindlimb blood flow during submaximal exercise.

    abstract：:Submaximal exercise diaphragm blood flow (BF) is elevated in young chronic heart failure (CHF) rats, while it is unknown if this occurs in older animals. Respiratory and hindlimb muscle BFs (radiolabeled microspheres) were measured at rest and during submaximal exercise (20m/min, 5% grade) in older healthy (n=7) and C...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2017.05.002

    authors： Smith JR,Hageman KS,Harms CA,Poole DC,Musch TI

    更新日期：2017-09-01 00:00:00

  • Modulation-demodulation hypothesis of periodic breathing in human respiration.

    abstract：:Periodic breathing (PB) is a diseased condition of the cardiorespiratory system, and mathematically it is modelled as an oscillation. Modeling approaches replicate periodic oscillation in the minute ventilation due to a higher than normal gain of the feedback signals from the chemoreceptors coupled with a longer than ...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2018.03.005

    authors： Pal T,Dutta PK,Maka S

    更新日期：2018-06-01 00:00:00

  • Developmental trajectories, critical windows and phenotypic alteration during cardio-respiratory development.

    abstract：:Embryo-environment interactions affecting cardio-respiratory development in vertebrates have been extensively studied, but an equally extensive conceptual framework for interpreting and interrelating these developmental events has lagged behind. In this review, we consider the conceptual constructs of "developmental p...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.resp.2011.05.001

    authors： Burggren WW,Reyna KS

    更新日期：2011-08-31 00:00:00

  • SiO2-induced release of sVEGFRs from pulmonary macrophages.

    abstract：BACKGROUND:The inhalation of silicon dioxide (SiO2) particles causes silicosis, a stubborn pulmonary disease that is characterized by alveolar inflammation during the early stage. Soluble cytokine receptors (SCRs) play important roles in regulating inflammation by either attenuating or promoting cytokine signaling. How...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2017.08.015

    authors： Chao J,Lv Y,Chen J,Wang J,Yao H

    更新日期：2018-01-01 00:00:00

  • Nitric oxide inhibitor altitude-dependently elevates pulmonary arterial pressure in high-altitude adapted yaks.

    abstract：:We studied the effect of N(w)-nitro-L-arginine (NLA) on yak pulmonary vascular tone in a climatic (hypobaric/hyperbaric adjusted) chamber. Five young male yaks that had been born and reared at an altitude greater than 3800 m a.s.l. were used. After measuring control values, 20 mg/kg of NLA was administered via the jug...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2004.12.002

    authors： Ishizaki T,Koizumi T,Ruan Z,Wang Z,Chen Q,Sakai A

    更新日期：2005-04-15 00:00:00

  • The impact of micro-embolism size on haemodynamic changes in the pulmonary micro-circulation.

    abstract：:Embolus occlusion of pulmonary arteries can result in elevated pulmonary blood pressures, often resulting in pulmonary hypertension (PH). Experimental observations have shown that small emboli (diameter <170 μm) can have a disproportionate effect on pulmonary vascular resistance (PVR) compared with larger emboli for t...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2010.12.018

    authors： Clark AR,Burrowes KS,Tawhai MH

    更新日期：2011-03-15 00:00:00

  • Effect of medroxyprogesterone on inspiratory flow shapes during sleep in postmenopausal women.

    abstract：:We previously showed that medroxyprogesterone acetate (MPA) effectively decreases the arterial CO(2) levels in postmenopausal women with partial upper airway obstruction. The aim of the present study was to analyze the effects of MPA on the inspiratory flow shapes during sleep. Eight postmenopausal women with hypoxemi...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 临床试验,杂志文章

    doi：10.1016/s1569-9048(02)00208-2

    authors： Saaresranta T,Aittokallio T,Polo-Kantola P,Helenius H,Polo O

    更新日期：2003-03-03 00:00:00

  • Ventilatory control in ALS.

    abstract：:Amyotrophic lateral sclerosis (ALS) is a fatal, progressive neurodegenerative disease. ALS selectively causes degeneration in upper and lower (spinal) motor neurons, leading to muscle weakness, paralysis and death by ventilatory failure. Although ventilatory failure is generally the cause of death in ALS, little is kn...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.resp.2013.05.016

    authors： Nichols NL,Van Dyke J,Nashold L,Satriotomo I,Suzuki M,Mitchell GS

    更新日期：2013-11-01 00:00:00

  • Glucocorticoids inhibits the repair of airway epithelial cells via the activation of wnt pathway.

    abstract：BACKGROUND:The purpose of this study was to explore the effect of Wnt pathway on the inhibition of airway epithelial cells repair by glucocorticoid. MATERIALS AND METHODS:The expression of E-cadherin in asthma mice model was detected by immunocytochemistry. XAV939 was used to treat 16HBE, and the expressions of relate...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2019.103283

    authors： Yu Z,Jiang Y,Sun C

    更新日期：2020-01-01 00:00:00

  • Effects of Eucalyptol in respiratory system mechanics on acute lung injury after exposure to short-term cigarette smoke.

    abstract：:Eucalyptol is a compound that has demonstrated antioxidant, anti-inflammatory and bronchodilator effects, but there are no investigations about the effects of this constituent on the respiratory system mechanics in relation to acute lung injury caused by short-term cigarette smoke (CS) exposure. In view of the above, ...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2019.04.007

    authors： Gondim FL,Serra DS,Cavalcante FSÁ

    更新日期：2019-08-01 00:00:00

  • Neuromolecular mechanisms mediating the effects of chronic intermittent hypoxia on adrenal medulla.

    abstract：:Sleep disordered breathing (SDB) with recurrent apnea is a major health problem affecting several million adult men and women. Humans with SDB are prone to develop hypertension. Studies on rodents established that exposure to chronic intermittent hypoxia (CIH) alone is sufficient to induce hypertension similar to that...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.resp.2015.01.001

    authors： Kumar GK,Nanduri J,Peng YJ,Prabhakar NR

    更新日期：2015-04-01 00:00:00

  • Oral treatment with desipramine improves breathing and life span in Rett syndrome mouse model.

    abstract：:Rett syndrome is a neurodevelopmental disease due to Mecp2 gene mutations that is associated to complex neurological symptoms, with bioaminergic deficits and life-threatening apneas related to sudden and unexpected death. In male mice, Mecp2-deficiency similarly induces medullary bioaminergic deficits, severe apneas a...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2007.08.009

    authors： Zanella S,Mebarek S,Lajard AM,Picard N,Dutschmann M,Hilaire G

    更新日期：2008-01-01 00:00:00

  • Supine changes in lung function correlate with chronic respiratory failure in myotonic dystrophy patients.

    abstract：:Quality of life and prognosis of patients with myotonic dystrophy type 1 (MD1) often depend on the degree of lung function impairment. This study was designed to assess the respective prevalence of ventilatory restriction, hypoxaemia and hypercapnia in MD1 patients and to determine whether postural changes in lung fun...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2014.01.006

    authors： Poussel M,Kaminsky P,Renaud P,Laroppe J,Pruna L,Chenuel B

    更新日期：2014-03-01 00:00:00

  • Correlations between the circadian patterns of body temperature, metabolism and breathing in rats.

    abstract：:It had been demonstrated previously that the circadian patterns of activity and state of arousal are not essential for the manifestation of the daily patterns of pulmonary ventilation (V(E)), tidal volume (V(T)) and breathing frequency (f). In this study we investigated the extent of the linkage between the circadian ...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2006.05.007

    authors： Mortola JP

    更新日期：2007-02-15 00:00:00

  • Early postnatal exposure to allergen and ozone leads to hyperinnervation of the pulmonary epithelium.

    abstract：:Airway injury in infant monkeys exposed to ozone and/or house dust mite allergen (HDMA) is associated with a loss of epithelial innervation. In this study, we evaluated for persistence/recovery of the altered epithelial innervation. Thirty-day-old rhesus monkeys were exposed to repeated episodes of HDMA and/or ozone f...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2006.03.002

    authors： Kajekar R,Pieczarka EM,Smiley-Jewell SM,Schelegle ES,Fanucchi MV,Plopper CG

    更新日期：2007-01-15 00:00:00

  • Multiple neural circuits mediating airway sensations: Recent advances in the neurobiology of the urge-to-cough.

    abstract：:The respiratory system is densely innervated by sensory neurons arising from the jugular (superior) and nodose (inferior) vagal ganglia. However, a distinction exists between jugular and nodose neurons as these ganglia developmentally originate from the neural crest and the epibranchial placodes, respectively. This di...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.resp.2015.09.017

    authors： Driessen AK,Farrell MJ,Mazzone SB,McGovern AE

    更新日期：2016-06-01 00:00:00

  • Differential responses of autonomic function in sea level residents, acclimatized lowlanders at >3500 m and Himalayan high altitude natives at >3500 m: A cross-sectional study.

    abstract：:We studied the differential responses of autonomic function in sea level residents (SLR), acclimatized lowlanders (ALH) in high altitude (HA) and HA natives (HAN) at >3500 m. Out of 771 male volunteers included in this cross-sectional study, SLR, ALH and HAN groups were comprised of 351, 307 and 113 volunteers, respec...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.resp.2018.04.002

    authors： Dhar P,Sharma VK,Das SK,Barhwal K,Hota SK,Singh SB

    更新日期：2018-08-01 00:00:00

  • Hypercapnia attenuates inspiratory amplitude and expiratory time responsiveness to hypoxia in vagotomized and vagal-intact rats.

    abstract：:A negative influence of central chemosensitivity on peripheral chemoreflex response has been demonstrated recently in a decerebrate-vagotomized rat preparation in situ with separate carotid body and brainstem perfusions. Here, we report similar negative influences of hypercapnia on the hypoxic respiratory response in ...

    journal_title：Respiratory physiology & neurobiology

    pub_type： 杂志文章

    doi：10.1016/j.resp.2012.01.008

    authors： Tin C,Song G,Poon CS

    更新日期：2012-04-15 00:00:00