Abstract:
:Dual terahertz (THz) comb spectroscopy enables high spectral resolution, high spectral accuracy, and broad spectral coverage; however, the requirement for dual stabilized femtosecond lasers hampers its versatility. We here report the first demonstration of dual THz comb spectroscopy using a single free-running fibre laser. By tuning the cavity-loss-dependent gain profile with an intracavity Lyot filter together with precise management of the cavity length and dispersion, dual-wavelength comb light beams with slightly detuned repetition frequencies are generated in a single laser cavity. Due to sharing of the same cavity, such comb light beams suffer from common-mode fluctuation of the repetition frequency, and hence the corresponding frequency difference between them is passively stable around a few hundred hertz within millihertz fluctuation. While greatly reducing the size, complexity, and cost of the laser source by use of a single free-running fibre laser, the dual THz comb spectroscopy system maintains a spectral bandwidth and dynamic range of spectral power comparable to a system equipped with dual stabilized fibre lasers, and can be effectively applied to high-precision spectroscopy of acetonitrile gas at atmospheric pressure. The demonstrated results indicate that this system is an attractive solution for practical applications of THz spectroscopy and other applications.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Hu G,Mizuguchi T,Oe R,Nitta K,Zhao X,Minamikawa T,Li T,Zheng Z,Yasui Tdoi
10.1038/s41598-018-29403-9subject
Has Abstractpub_date
2018-07-24 00:00:00pages
11155issue
1issn
2045-2322pii
10.1038/s41598-018-29403-9journal_volume
8pub_type
杂志文章abstract::The impacts of climatic changes on forests may appear gradually on time scales of years to centuries due to the long generation times of trees. Consequently, current forest extent may not reflect current climatic patterns. In contrast with these lagged responses, abrupt transitions in forests under climate change may ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-24642-2
更新日期:2018-04-30 00:00:00
abstract::Fundamental understanding of guest gas replacement in hydrate reservoirs is crucial for the enhanced recovery of natural gas and carbon dioxide (CO2) sequestration. To gain physical insight into this exchange process, this work aims at developing and validating a clathrate hydrate model for gas replacement. Most of th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-55476-1
更新日期:2019-12-11 00:00:00
abstract::We used Mendelian randomization to estimate the causal effects of the liver enzymes, alanine aminotransferase (ALT), alkaline phosphatase (ALP) and gamma glutamyltransferase (GGT), on diabetes and cardiovascular disease, using genetic variants predicting these liver enzymes at genome wide significance applied to exten...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep38813
更新日期:2016-12-20 00:00:00
abstract::The Zika virus (ZIKV) outbreak in the Americas and South Pacific poses a significant burden on human health because of ZIKV's neurotropic effects in the course of fetal development. Vaccine candidates against ZIKV are coming online, but immunological tools to study anti-ZIKV responses in preclinical models, particular...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-00193-w
更新日期:2017-03-21 00:00:00
abstract::This study aimed to compare the effects of volatile anesthesia and total intravenous anesthesia (TIVA) on syndecan-1 shedding in patients with gastric cancer undergoing minimally invasive gastrectomy. Patients were randomly assigned to either the Volatile (n = 68) or the TIVA (n = 68) group. Anesthesia was maintained ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-021-81012-1
更新日期:2021-01-15 00:00:00
abstract::Gene essentiality changes are crucial for organismal evolution. However, it is unclear how essentiality of orthologs varies across species. We investigated the underlying mechanism of gene essentiality changes between yeast and mouse based on the framework of network evolution and comparative genomic analysis. We foun...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep00900
更新日期:2012-01-01 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Scientific reports
pub_type: 已发布勘误
doi:10.1038/s41598-019-55022-z
更新日期:2019-12-05 00:00:00
abstract::The production of tuberous roots is usually reduced by vigorous vegetative growth because of the competition for resource between the vegetative parts and reproductive organs. In this study, we conducted root pruning to examine the vigorous vegetative growth by regulating root growth, subsequently limiting vegetative ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-22586-1
更新日期:2018-03-13 00:00:00
abstract::Lipid mediators play pivotal roles in colorectal cancer and colitis, but only a limited member of the phospholipase A2 (PLA2) subtypes, which lie upstream of various lipid mediators, have been implicated in the positive or negative regulation of these diseases. Clinical and biochemical evidence suggests that secreted ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-12434-z
更新日期:2017-09-25 00:00:00
abstract::Tunneling nanotubes (TNTs) are actin-based membranous structures bridging distant cells for intercellular communication. We define roles for TNTs in stress adaptation and treatment resistance in prostate cancer (PCa). Androgen receptor (AR) blockade and metabolic stress induce TNTs, but not in normal prostatic epithel...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-44346-5
更新日期:2019-05-24 00:00:00
abstract::Abnormal dopaminergic transmission has been implicated as a risk determinant of HIV-1-associated neurocognitive disorders. HIV-1 Tat protein increases synaptic dopamine (DA) levels by directly inhibiting DA transporter (DAT) activity, ultimately leading to dopaminergic neuron damage. Through integrated computational m...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep39048
更新日期:2016-12-14 00:00:00
abstract::Down syndrome (DS), caused by trisomy of chromosome 21, is one of the most common genetic disorders. Patients with DS display growth retardation and inevitably develop characteristic Alzheimer's disease (AD) neuropathology, including neurofibrillary tangles and neuritic plaques. The expression of amyloid precursor pro...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep22460
更新日期:2016-03-03 00:00:00
abstract::Altered death receptor signaling and resistance to subsequent apoptosis is an important clinical resistance mechanism. Here, we investigated the role of death receptor resistance in breast cancer progression. Resistance of the estrogen receptor alpha (ER)-positive, chemosensitive MCF7 breast cancer cell line to tumor ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep00539
更新日期:2012-01-01 00:00:00
abstract::Protandric species switch sex during their lifetime. According to theory, the time (body size) at which sex change occurs is determined by the reproductive success of individuals affected by social interactions as well as by post-copulatory factors. Experimental evidence is biased to few social systems making the expl...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep29439
更新日期:2016-07-07 00:00:00
abstract::Benign prostatic hyperplasia (BPH) is one of the most common diseases in middle-aged and elderly men. In the present study, we aimed to compare the efficacy and safety of thulium laser resection of the prostate (TMLRP) with either transurethral plasmakinetic resection of the prostate (TUPKP) or transurethral resection...
journal_title:Scientific reports
pub_type: 杂志文章,meta分析
doi:10.1038/srep14542
更新日期:2015-10-07 00:00:00
abstract::Topologically distinct magnetic structures like skyrmions, domain walls, and the uniformly magnetized state have multiple applications in logic devices, sensors, and as bits of information. One of the most promising concepts for applying these bits is the racetrack architecture controlled by electric currents or magne...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-77337-y
更新日期:2020-11-23 00:00:00
abstract::Pachychoroid spectrum diseases have attracted increasing attention, though their pathophysiology has yet to be fully elucidated. In this study, we assessed the vascular diameters of vortex veins in pachychoroid spectrum diseases such as central serous chorioretinopathy (CSC), pachychoroid neovasculopathy without polyp...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-75789-w
更新日期:2020-11-11 00:00:00
abstract::We consider the finite-temperature properties of the extended Bose-Hubbard model realized recently in an ETH experiment [Nature 532, 476 (2016)]. Competing short- and global-range interactions accommodate fascinating collective phenomena. We formulate a self-consistent mean-field theory to describe the behaviors of th...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-66054-1
更新日期:2020-06-03 00:00:00
abstract::The Rho-family small GTPase Cdc42 localizes at plasma membrane and Golgi complex and aside from protrusion and migration operates in vesicle trafficking, endo- and exocytosis as well as establishment and/or maintenance of cell polarity. The formin family members FMNL2 and -3 are actin assembly factors established to r...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-017-09952-1
更新日期:2017-08-29 00:00:00
abstract::Organic-inorganic hybrid photodetectors attract considerable attention because they can combine the advantages of both organic and inorganic systems. Here, a perovskite compound with a broad absorption spectrum and high power conversion efficiency is used as a photosensitive layer in an organic/inorganic hybrid hetero...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep07902
更新日期:2015-01-20 00:00:00
abstract::Lipofectamine reagents are widely accepted as "gold-standard" for the safe delivery of exogenous DNA or RNA into cells. Despite this, a satisfactory mechanism-based explanation of their superior efficacy has remained mostly elusive thus far. Here we apply a straightforward combination of live cell imaging, single-part...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep25879
更新日期:2016-05-11 00:00:00
abstract::Delphinidin is a flavonoid belonging to dietary anthocyanidin family that has been reported to possess diverse anti-tumoral activities. However, the effects of delphinidin on colorectal cancer (CRC) cells and the underlying mechanisms are not fully understood. Thus, we aimed to investigate the anti-cancer activity of ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-019-55505-z
更新日期:2019-12-12 00:00:00
abstract::ADP-ribosyltransferases (ARTs) modify proteins with single units or polymers of ADP-ribose to regulate DNA repair. However, the substrates for these enzymes are ill-defined. For example, although histones are modified by ARTs, the sites on these proteins ADP-ribosylated following DNA damage and the ARTs that catalyse ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep43750
更新日期:2017-03-02 00:00:00
abstract::Dental caries is an important public health problem worldwide. This study aims to prove how preventive therapies reduce the onset of caries in adult patients, and to identify patients with high or low risk of caries by using Classification and Regression Trees based survival analysis (survival CART). A clinical data s...
journal_title:Scientific reports
pub_type: 杂志文章,多中心研究
doi:10.1038/srep29190
更新日期:2016-07-06 00:00:00
abstract::Auricle defects are important and common occurrences in forensic medicine. The accurate measurement and assessment of auricle defects is key to identifying and evaluating injury, and the currently available methods are known to be labor intensive and inaccurate. In this paper, we introduce an identification and docume...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-21289-x
更新日期:2018-02-12 00:00:00
abstract::Polyphenol oxidases (PPOs) are ubiquitously distributed among plants, bacteria, fungi and animals. They catalyze the hydroxylation of monophenols (monophenolase activity) and the oxidation of o-diphenols (diphenolase activity) to o-quinones. PPOs are commonly present as an isoenzyme family. In walnut (Juglans regia), ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-020-67415-6
更新日期:2020-07-02 00:00:00
abstract::Improving dewaterability of sludge is important for the disposal of sludge in wastewater treatment plants (WWTPs). This study, for the first time, investigated the Fe(II) activated oxidization processes in improving anaerobically digested sludge (ADS) dewaterability. The combination of Fe(II) (0-100 mg/g total solids ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep24800
更新日期:2016-04-25 00:00:00
abstract::Development of novel anti-influenza A virus (IAV) drugs with high efficiency and low toxicity is critical for preparedness against influenza outbreaks. Herein, we investigated the anti-IAV activities and mechanisms of fucoidan in vitro and in vivo. The results showed that a fucoidan KW derived from brown algae Kjellma...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep40760
更新日期:2017-01-17 00:00:00
abstract::Modelling the biokinetics of radionuclide excretion or retention is important in nuclear medicine and following accidental/malicious radioactivity releases. Sums of discrete exponential decay rates are often used, but we hypothesized that continuous probability distributions (CPD) of decay rates can describe the data ...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/s41598-018-38046-9
更新日期:2019-02-04 00:00:00
abstract::Recently, a concept of digital metamaterials has been proposed to manipulate field distribution through proper spatial mixtures of digital metamaterial bits. Here, we present a design of 2-bit digitally-controlled coding metasurface that can effectively modulate the scattered electromagnetic wave and realize different...
journal_title:Scientific reports
pub_type: 杂志文章
doi:10.1038/srep42302
更新日期:2017-02-08 00:00:00