Identification of the amino acid position controlling the different enzymatic activities in walnut tyrosinase isoenzymes (jrPPO1 and jrPPO2).

abstract：:When acids are supplied with an excess electron (or placed in an Ar or the more polarizable N2 matrix) in the presence of species such as NH3, the formation of ion-pairs is a likely outcome. Using density functional theory and first-principles calculations, however, we show that, without supplying an external electron...

journal_title：Scientific reports

authors： Varadwaj PR,Varadwaj A,Marques HM

更新日期：2019-07-23 00:00:00

abstract：:Cyanobacteria harbor unique photoreceptors, designated as cyanobacteriochromes (CBCRs). In this study, we attempted to engineer the chromatic acclimation sensor CcaS, a CBCR derived from the cyanobacterium Synechocystis sp. PCC 6803. The wild-type CcaS induces gene expression under green light illumination and repress...

journal_title：Scientific reports

authors： Nakajima M,Ferri S,Rögner M,Sode K

更新日期：2016-11-24 00:00:00

abstract：:Do scientists follow hot topics in their scientific investigations? In this paper, by performing analysis to papers published in the American Physical Society (APS) Physical Review journals, it is found that papers are more likely to be attracted by hot fields, where the hotness of a field is measured by the number of...

journal_title：Scientific reports

authors： Wei T,Li M,Wu C,Yan XY,Fan Y,Di Z,Wu J

更新日期：2013-01-01 00:00:00

abstract：:Protocadherin 19 (Pcdh19) is an X-linked gene belonging to the protocadherin superfamily, whose members are predominantly expressed in the central nervous system and have been implicated in cell-cell adhesion, axon guidance and dendrite self-avoidance. Heterozygous loss-of-function mutations in humans result in the ch...

journal_title：Scientific reports

authors： Pederick DT,Homan CC,Jaehne EJ,Piltz SG,Haines BP,Baune BT,Jolly LA,Hughes JN,Gecz J,Thomas PQ

更新日期：2016-05-31 00:00:00

abstract：:Melamine detection has attracted much attention since the discovery of the damage of melamine to human health. Herein, we have developed a sensitive homogeneous electroanalytical platform for melamine detection, which is relied on the formation of triplex molecular beacon integrated with exonuclease III (Exo III)-medi...

journal_title：Scientific reports

authors： Liu X,Song M,Li F

更新日期：2017-07-03 00:00:00

abstract：:Proton therapy as a promising candidate in cancer treatment has attracted much attentions and many studies have been performed to investigate the new methods to enhance its radiation effectiveness. In this regard, two research groups have suggested that using boron isotopes will lead to a radiation effectiveness enhan...

journal_title：Scientific reports

authors： Tabbakh F,Hosmane NS

更新日期：2020-03-25 00:00:00

abstract：:The sinusoidal endothelial cells present in the liver (LSECs) are tipically characterized by the presence of pores (fenestrae). During some pathological conditions LSECs undergo "capillarization", a process characterized by loss of fenestrations and acquisition of a vascular phenotype. In chronic liver disease capilla...

journal_title：Scientific reports

authors： Baiocchini A,Del Nonno F,Taibi C,Visco-Comandini U,D'Offizi G,Piacentini M,Falasca L

更新日期：2019-06-19 00:00:00

abstract：:Cell therapies that invoke pleiotropic mechanisms may facilitate functional recovery in patients with stroke. Based on previous experiments using microglia preconditioned by oxygen-glucose deprivation, we hypothesized that the administration of peripheral blood mononuclear cells (PBMCs) preconditioned by oxygen-glucos...

journal_title：Scientific reports

authors： Hatakeyama M,Kanazawa M,Ninomiya I,Omae K,Kimura Y,Takahashi T,Onodera O,Fukushima M,Shimohata T

更新日期：2019-11-14 00:00:00

abstract：:L-selectin on T-cells is best known as an adhesion molecule that supports recruitment of blood-borne naïve and central memory cells into lymph nodes. Proteolytic shedding of the ectodomain is thought to redirect activated T-cells from lymph nodes to sites of infection. However, we have shown that activated T-cells re-...

journal_title：Scientific reports

authors： Mohammed RN,Wehenkel SC,Galkina EV,Yates EK,Preece G,Newman A,Watson HA,Ohme J,Bridgeman JS,Durairaj RRP,Moon OR,Ladell K,Miners KL,Dolton G,Troeberg L,Kashiwagi M,Murphy G,Nagase H,Price DA,Matthews RJ,Knäuper V

更新日期：2019-04-02 00:00:00

abstract：:The AB0 blood group has been linked to ischaemic heart disease, stroke, and periodontal disease, while the Lewis blood group has been linked to ischaemic heart disease and obesity, all of which have been associated with periodontitis. AB0 or Lewis blood group phenotype may therefore constitute common hereditary compon...

journal_title：Scientific reports

authors： Enevold C,Nielsen CH,Molbo D,Lund R,Bendtzen K,Fiehn N-,Holmstrup P

更新日期：2019-04-18 00:00:00

abstract：:China's reported cases of Human Immunodeficiency Virus (HIV) and AIDS increased from over 50000 in 2011 to more than 130000 in 2017, while AIDS related search indices on Baidu from 2.1 million to 3.7 million in the same time periods. In China, people seek AIDS related knowledge from Baidu which one of the world's larg...

journal_title：Scientific reports

authors： Li K,Liu M,Feng Y,Ning C,Ou W,Sun J,Wei W,Liang H,Shao Y

更新日期：2019-01-23 00:00:00

abstract：:Episodic memories are long lasting and full of detail, yet imperfect and malleable. We quantitatively evaluated recollection of short audiovisual segments from movies as a proxy to real-life memory formation in 161 subjects at 15 minutes up to a year after encoding. Memories were reproducible within and across individ...

journal_title：Scientific reports

authors： Tang H,Singer J,Ison MJ,Pivazyan G,Romaine M,Frias R,Meller E,Boulin A,Carroll J,Perron V,Dowcett S,Arellano M,Kreiman G

更新日期：2016-09-30 00:00:00

abstract：:Previous work has shown that human vision performs spatial integration of luminance contrast energy, where signals are squared and summed (with internal noise) over area at detection threshold. We tested that model here in an experiment using arrays of micro-pattern textures that varied in overall stimulus area and sp...

journal_title：Scientific reports

authors： Baker DH,Meese TS

更新日期：2016-07-27 00:00:00

abstract：:The receptor guanylate cyclases (rGCs) in animals serve as sensitive chemoreceptors to detect both chemical and environmental cues. In reproduction, rGCs were shown to be expressed on sperm and serve as receptors for egg-derived sperm-activating and sperm-attracting factors in some echinoderms and mammals. However, sp...

journal_title：Scientific reports

authors： Zhang Y,Chiu YL,Chen CJ,Ho YY,Shinzato C,Shikina S,Chang CF

更新日期：2019-10-10 00:00:00

abstract：:This study aims to prepare, characterize and evaluate the pharmacokinetics of liposomal donepezil HCl (LDH) dispersed into thiolated chitosan hydrogel (TCH) in rabbits. Various hydrogels including TCH were prepared, and after characterization, TCH was selected for subsequent evaluations, due to the promising results. ...

journal_title：Scientific reports

authors： Al Harthi S,Alavi SE,Radwan MA,El Khatib MM,AlSarra IA

更新日期：2019-07-02 00:00:00

abstract：:In the last 40 years only one new antitubercular drug has been approved, whilst resistance to current drugs, including rifampicin, is spreading. Here, we used the model organism Mycobacterium smegmatis to study mechanisms of phenotypic mycobacterial resistance, employing quantitative mass spectrometry-based proteomics...

journal_title：Scientific reports

authors： Giddey AD,de Kock E,Nakedi KC,Garnett S,Nel AJ,Soares NC,Blackburn JM

更新日期：2017-03-06 00:00:00

abstract：:Understanding adipose tissue cellular heterogeneity and homeostasis is essential to comprehend the cell type dynamics in metabolic diseases. Cellular subpopulations in the adipose tissue have been related to disease development, but efforts towards characterizing the adipose tissue cell type composition are limited. H...

journal_title：Scientific reports

authors： Lenz M,Arts ICW,Peeters RLM,de Kok TM,Ertaylan G

更新日期：2020-06-26 00:00:00

abstract：:Eucalyptus globulus is an aromatic medicinal plant which known for its 1,8-cineole main pharmacological constituent exhibits as natural analgesic agent. Eucalyptus globulus-loaded micellar nanoparticle was developed via spontaneous emulsification technique and further evaluation for its analgesic efficacy study, in vi...

journal_title：Scientific reports

authors： Aziz ZAA,Nasir HM,Ahmad A,Setapar SHM,Ahmad H,Noor MHM,Rafatullah M,Khatoon A,Kausar MA,Ahmad I,Khan S,Al-Shaeri M,Ashraf GM

更新日期：2019-09-23 00:00:00

abstract：:Several prenatal and perinatal factors have been found to be associated with developmental dyslexia (reading disorder) in alphabetic language. Given the absence of relevant studies of Chinese children, the present study tries to investigate these risk factors. A total of 45,850 students were recruited from grades thre...

journal_title：Scientific reports

authors： Liu L,Wang J,Shao S,Luo X,Kong R,Zhang X,Song R

更新日期：2016-11-07 00:00:00

abstract：:Quantum walk is a key operation in quantum computing, simulation, communication and information. Here, we report for the first time the demonstration of quantum walks and localized quantum walks in a new type of optical fibers having a ring of cores constructed with both periodic and quasiperiodic Fibonacci sequences,...

journal_title：Scientific reports

authors： Nguyen DT,Nguyen TA,Khrapko R,Nolan DA,Borrelli NF

更新日期：2020-04-28 00:00:00

abstract：:Whether the retinal process alone or retinal and cortical processes jointly determine afterimage (AI) formation has long been debated. Based on the retinal rebound responses, recent work proposes that afterimage signals are exclusively generated in the retina, although later modified by cortical mechanisms. We tested ...

journal_title：Scientific reports

authors： Dong B,Holm L,Bao M

更新日期：2017-01-23 00:00:00

abstract：:Complex systems, arising in many contexts in the computer, life, social, and physical sciences, have not shared a generally-accepted complexity measure playing a fundamental role as the Shannon entropy H in statistical mechanics. Superficially-conflicting criteria of complexity measurement, i.e. complexity-randomness ...

journal_title：Scientific reports

authors： Ke DG

更新日期：2013-01-01 00:00:00

abstract：:A negative correlation between body size and the latitudinal temperature gradient is well established for extant terrestrial endotherms but less so in the fossil record. Here we analyze the middle Eocene site of Geiseltal (Germany), whose record is considered to span ca. 5 Myrs of gradual global cooling, and generate ...

journal_title：Scientific reports

authors： Ring SJ,Bocherens H,Wings O,Rabi M

更新日期：2020-03-04 00:00:00

abstract：:The pulsed events of rainstorm erosion on the Loess Plateau are well-known, but little information is available concerning the characteristics of superficial soil erosion processes caused by heavy rainstorms at the watershed scale. This study statistically evaluated characteristics of pulsed runoff-erosion events base...

journal_title：Scientific reports

authors： Wu L,Jiang J,Li GX,Ma XY

更新日期：2018-02-27 00:00:00

abstract：:In this study, genomic DNA was screened from Halobacillus andaensis NEAU-ST10-40T by selection in Escherichia coli KNabc lacking three major Na+/H+ antiporters. One gene designated upf0118 exhibiting Na+(Li+)/H+ antiport activity was finally cloned. Protein alignment showed that UPF0118 shares the highest identity of ...

journal_title：Scientific reports

authors： Dong P,Wang L,Song N,Yang L,Chen J,Yan M,Chen H,Zhang R,Li J,Abdel-Motaal H,Jiang J

更新日期：2017-04-04 00:00:00

abstract：:Telomerase activation and telomere maintenance are critical for cellular immortalization and transformation. PIN2/TERF1-interacting telomerase inhibitor 1 (PinX1) is a telomerase regulator and the aberrant expression of PinX1 causes telomere shortening. Identifying PinX1-interacting proteins is important for understan...

journal_title：Scientific reports

authors： Cheung DH,Ho ST,Lau KF,Jin R,Wang YN,Kung HF,Huang JJ,Shaw PC

更新日期：2017-03-03 00:00:00

abstract：:Climatic fluctuations largely affects species turnover and cause major shifts of terrestrial ecosystem. In the present study the five decade old herbarium specimens of lichens were compared with recent collection from Darjeeling district with respect to elements, PAHs accumulation and carbon isotope composition (δ(13)...

journal_title：Scientific reports

authors： Bajpai R,Mishra S,Dwivedi S,Upreti DK

更新日期：2016-08-09 00:00:00

abstract：:Sea surface temperature (SST) is a fundamental driver of tropical weather systems such as monsoon rainfall and tropical cyclones. However, understanding of the factors that control SST variability is lacking, especially during the monsoons when in situ observations are sparse. Here we use a ground-breaking observation...

journal_title：Scientific reports

authors： Vijith V,Vinayachandran PN,Webber BGM,Matthews AJ,George JV,Kannaujia VK,Lotliker AA,Amol P

更新日期：2020-04-27 00:00:00

abstract：:Hypoadiponectinemia and adiponectin resistance are implicated in the aetiology of obesity-related cardiometabolic disorders, hence represent a potential therapeutic axis. Here we characterised the effects of in vivo electrotransfer-mediated overexpression of the adiponectin receptors, AdipoR1 or AdipoR2, into tibialis...

journal_title：Scientific reports

authors： Keshvari S,Henstridge DC,Ng C,Febbraio MA,Whitehead JP

更新日期：2017-02-01 00:00:00

abstract：:Honeybees (Apis mellifera L.), which unquestionably play an economically important role in pollination and agricultural production, are at risk of decline. To study changes in gene expression in insects upon exposure to pesticides or other external stimuli, appropriate reference genes are required for data normalizati...

journal_title：Scientific reports

authors： Wieczorek P,Frąckowiak P,Obrępalska-Stęplowska A

更新日期：2020-09-30 00:00:00