Vibration and damping characteristics of 3D printed Kagome lattice with viscoelastic material filling.

abstract：:We propose a novel class of mixed fluctuations with different orientations and fractal scaling features as a model for anisotropic two-dimensional (2D) trajectories hypothesized to appear in complex systems. Furthermore, we develop the oriented fractal scaling component analysis (OFSCA) to decompose such mixed fluctua...

journal_title：Scientific reports

authors： Seleznov I,Popov A,Kikuchi K,Kolosova E,Kolomiiets B,Nakata A,Kaneko M,Kiyono K

更新日期：2020-12-14 00:00:00

abstract：:A synthetic monoketone analog of curcumin, termed 3, 5-bis (2-flurobenzylidene) piperidin-4-one (EF24), has been reported to inhibit the growth of a variety of cancer cells both in vitro and in vivo. However, whether EF24 has anticancer effects on cholangiocarcinoma (CCA) cells and the mechanisms remain to be investig...

journal_title：Scientific reports

authors： Yin DL,Liang YJ,Zheng TS,Song RP,Wang JB,Sun BS,Pan SH,Qu LD,Liu JR,Jiang HC,Liu LX

更新日期：2016-08-30 00:00:00

abstract：:In a previous study, we demonstrated that topical D-beta-hydroxybutyrate ameliorates corneal epithelial erosion and superficial punctate keratopathy in a rat model of dry eye disease. In the current investigation, we performed a prospective, randomized, multicentre, double-blind, placebo-controlled study to assess the...

journal_title：Scientific reports

authors： Kawakita T,Uchino M,Fukagawa K,Yoshino K,Shimazaki S,Toda I,Tanaka M,Arai H,Sakatani K,Hata S,Okano T,Tsubota K

更新日期：2016-02-11 00:00:00

abstract：:Pannexin 1 (Panx1) forms ATP-permeable membrane channels that play roles in the nervous system. The analysis of roles in both standard and pathological conditions benefits from a model organism with rapid development and early onset of behaviors. Such a model was developed by ablating the zebrafish panx1a gene using T...

journal_title：Scientific reports

authors： Safarian N,Whyte-Fagundes P,Zoidl C,Grigull J,Zoidl G

更新日期：2020-06-12 00:00:00

abstract：:The FDA-approved prophylactic antimalarial drug atovaquone (ATO) recently was repurposed as an antitumor drug. Studies show that ATO exerts a profound antiproliferative effect in several cancer cells, including breast, ovarian, and glioma. Analogous to the mechanism of action proposed in parasites, ATO inhibits mitoch...

journal_title：Scientific reports

authors： Cheng G,Hardy M,Topchyan P,Zander R,Volberding P,Cui W,Kalyanaraman B

更新日期：2020-10-21 00:00:00

abstract：:As an important method for building blocks synthesis, whole cell biocatalysis is hindered by some shortcomings such as unpredictability of reactions, utilization of opportunistic pathogen, and side reactions. Due to its biological and extensively studied genetic background, Pseudomonas putida KT2440 is viewed as a pro...

journal_title：Scientific reports

authors： Wang Y,Lv M,Zhang Y,Xiao X,Jiang T,Zhang W,Hu C,Gao C,Ma C,Xu P

更新日期：2014-11-06 00:00:00

abstract：:To better understand the recognition mechanism of RISC and the repertoire of guide-target interactions we introduced G:U wobbles and mismatches at various positions of the microRNA (miRNA) 'seed' region and performed all-atom molecular dynamics simulations of the resulting Ago-miRNA:mRNA ternary complexes. Our simulat...

journal_title：Scientific reports

authors： Xia Z,Clark P,Huynh T,Loher P,Zhao Y,Chen HW,Ren P,Rigoutsos I,Zhou R

更新日期：2012-01-01 00:00:00

abstract：:Light damages photosynthetic machinery, primarily photosystem II (PSII), and it results in photoinhibition. A new photodamage model, the two-step photodamage model, suggests that photodamage to PSII initially occurs at the oxygen evolving complex (OEC) by light energy absorbed by manganese and that the PSII reaction c...

journal_title：Scientific reports

authors： Zavafer A,Cheah MH,Hillier W,Chow WS,Takahashi S

更新日期：2015-11-12 00:00:00

abstract：:We introduce a polarization-resolved terahertz time-domain spectrometer with a broadband (0.3-2.5 THz), rotatable THz polarization state, and which exhibits minimal change in the electric field amplitude and polarization state upon rotation. This was achieved by rotating an interdigitated photoconductive emitter, and ...

journal_title：Scientific reports

authors： Mosley CDW,Failla M,Prabhakaran D,Lloyd-Hughes J

更新日期：2017-09-26 00:00:00

abstract：:The influence of dose rate on radiation cataractogenesis has yet to be extensively studied. One recent epidemiological investigation suggested that protracted radiation exposure increases radiation-induced cataract risk: cumulative doses of radiation mostly <100 mGy received by US radiologic technologists over 5 years...

journal_title：Scientific reports

authors： Barnard SGR,McCarron R,Moquet J,Quinlan R,Ainsbury E

更新日期：2019-07-18 00:00:00

abstract：:Hydrothermal reduction is a promising approach for graphene oxide (GO) reduction since it is environmentally friendly, simple, and cost effective. We present a detailed study of structural changes occurring in graphene oxide during the reduction process. The correlations between the interlayer spacing, chemical states...

journal_title：Scientific reports

authors： Huang HH,De Silva KKH,Kumara GRA,Yoshimura M

更新日期：2018-05-01 00:00:00

abstract：:Globally, Aedes aegypti is one of the most dangerous mosquitoes that plays a crucial role as a vector for human diseases, such as yellow fever, dengue, and chikungunya. To identify (1) transcriptomic basis of midgut (2) key genes that are involved in the toxicity process by a comparative transcriptomic analysis betwee...

journal_title：Scientific reports

authors： Batool K,Alam I,Wu S,Liu W,Zhao G,Chen M,Wang J,Xu J,Huang T,Pan X,Yu X,Guan X,Xu L,Zhang L

更新日期：2018-08-23 00:00:00

abstract：:Hydraulic extended-reach limit (HERL) model of horizontal extended-reach well (ERW) can predict the maximum measured depth (MMD) of the horizontal ERW. The HERL refers to the well's MMD when drilling fluid cannot be normally circulated by drilling pump. Previous model analyzed the following two constraint conditions, ...

journal_title：Scientific reports

authors： Li X,Gao D,Chen X

更新日期：2017-06-08 00:00:00

abstract：:We consider the electromagnetic response of a topological Weyl semimetal (TWS) with a pair of Weyl nodes in the bulk and corresponding Fermi arcs in the surface Brillouin zone. We compute the frequency-dependent complex conductivities σαβ(ω) and also take into account the modification of Maxwell equations by the topol...

journal_title：Scientific reports

authors： Kargarian M,Randeria M,Trivedi N

更新日期：2015-08-03 00:00:00

abstract：:This study is to investigate the frequencies of T-helper (Th)22, Th17 and Th1 cells and the levels of related cytokines in subchondral bone marrow in patients with rheumatoid arthritis (RA). Bone marrow and peripheral blood samples were collected from RA, osteoarthritis (OA) patients and healthy controls. The frequenc...

journal_title：Scientific reports

authors： Li S,Yin H,Zhang K,Wang T,Yang Y,Liu X,Chang X,Zhang M,Yan X,Ren Y,Pan W,Zhang L

更新日期：2017-07-06 00:00:00

abstract：:Pro-inflammatory and amyloidogenic S100A9 protein is an important contributor to Alzheimer's disease (AD) pathology. Traumatic brain injury (TBI) is viewed as a precursor state for AD. Here we have shown that S100A9-driven amyloid-neuroinflammatory cascade was initiated in TBI and may serve as a mechanistic link betwe...

journal_title：Scientific reports

authors： Wang C,Iashchishyn IA,Pansieri J,Nyström S,Klementieva O,Kara J,Horvath I,Moskalenko R,Rofougaran R,Gouras G,Kovacs GG,Shankar SK,Morozova-Roche LA

更新日期：2018-08-27 00:00:00

abstract：:Gene set enrichment analysis (GSEA) associates gene sets and phenotypes, its use is predicated on the choice of a pre-defined collection of sets. The defacto standard implementation of GSEA provides seven collections yet there are no guidelines for the choice of collections and the impact of such choice, if any, is un...

journal_title：Scientific reports

authors： Bateman AR,El-Hachem N,Beck AH,Aerts HJ,Haibe-Kains B

更新日期：2014-02-13 00:00:00

abstract：:The side effects of cisplatin (CDDP), notably nephrotoxicity, greatly limited its use in clinical chemotherapy. HuangQi Injections (HI), a commonly used preparation of the well-known Chinese herbal medicine Astragali radix, appeared to be promising treatment for nephrotoxicity without compromising the anti-tumor activ...

journal_title：Scientific reports

authors： Li CY,Song HT,Wang XX,Wan YY,Ding XS,Liu SJ,Dai GL,Liu YH,Ju WZ

更新日期：2017-06-15 00:00:00

abstract：:Coincident climatic and human effects strongly influence water-quality properties in estuarine-coastal ecosystems around the world. Time-series data for a number of ecosystems reveal high spatio-temporal variability superimposed on secular trends traceable to nutrient over-enrichment. In this paper, we present new ana...

journal_title：Scientific reports

authors： Harding LW Jr,Mallonee ME,Perry ES,Miller WD,Adolf JE,Gallegos CL,Paerl HW

更新日期：2019-04-30 00:00:00

abstract：:The cholinergic system plays a major anti-inflammatory role in many diseases through acetylcholine (Ach) release after vagus nerve stimulation. Osteoarthritis (OA) is associated with local low-grade inflammation, but the regulatory mechanisms are unclear. Local Ach release could have anti-inflammatory activity since a...

journal_title：Scientific reports

authors： Courties A,Belle M,Senay S,Cambon-Binder A,Sautet A,Chédotal A,Berenbaum F,Sellam J

更新日期：2020-06-01 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Shkarina S,Shkarin R,Weinhardt V,Melnik E,Vacun G,Kluger PJ,Loza K,Epple M,Ivlev SI,Baumbach T,Surmeneva MA,Surmenev RA

更新日期：2018-11-29 00:00:00

abstract：:Post-infectious bronchiolitis obliterans (BO) could be diagnosed via spirometry and chest computed tomography (CT); however, these tests are limited in infants. We aimed to evaluate the utility of lung clearance index (LCI) and air-trapping lung volume from chest CT in infants. This prospective study included 20 infan...

journal_title：Scientific reports

authors： Kim YH,Shin HJ,Sol IS,Kim SY,Kim JD,Yoon H,Kim KW,Kim MJ,Lee MJ,Sohn MH

更新日期：2017-11-09 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Pereda M,Capraro V,Sánchez A

更新日期：2019-09-03 00:00:00

abstract：:Petunia × hybrida cv 'Mitchell Diploid' floral volatile benzenoid/phenylpropanoid (FVBP) biosynthesis ultimately produces floral volatiles derived sequentially from phenylalanine, cinnamic acid, and p-coumaric acid. In an attempt to better understand biochemical steps after p-coumaric acid production, we cloned and ch...

journal_title：Scientific reports

authors： Kim JY,Swanson RT,Alvarez MI,Johnson TS,Cho KH,Clark DG,Colquhoun TA

更新日期：2019-06-20 00:00:00

abstract：:Available CFTR modulators provide no therapeutic benefit for cystic fibrosis (CF) caused by many loss-of-function mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) chloride channel, including N1303K. We previously introduced the concept of 'co-potentiators' (combination-potentiators) to rescu...

journal_title：Scientific reports

authors： Phuan PW,Tan JA,Rivera AA,Zlock L,Nielson DW,Finkbeiner WE,Haggie PM,Verkman AS

更新日期：2019-11-27 00:00:00

abstract：:The development of selective visual attention is critical for effectively engaging with an ever-changing world. Its optimal deployment depends upon interactions between neural, motor, and sensory systems across multiple timescales and neurocognitive loci. Previous work illustrates the spatio-temporal dynamics of these...

journal_title：Scientific reports

authors： Stallworthy IC,Sifre R,Berry D,Lasch C,Smith TJ,Elison JT

更新日期：2020-10-14 00:00:00

abstract：:The immune system is constantly challenged, being required to protect the organism against a wide variety of infectious pathogens and, at the same time, to avoid autoimmune disorders. One of the most important molecules involved in these events is the Major Histocompatibility Complex class I (MHC-I), responsible for b...

journal_title：Scientific reports

authors： Rigo MM,Antunes DA,Vaz de Freitas M,Fabiano de Almeida Mendes M,Meira L,Sinigaglia M,Vieira GF

更新日期：2015-12-17 00:00:00

abstract：:Rhegmatogenous retinal detachment (RRD) is an ophthalmic emergency, which usually requires prompt surgery to prevent further detachment and restore sensory function. Although several individual factors have been suggested, a systems level understanding of molecular pathomechanisms underlying this severe eye disorder i...

journal_title：Scientific reports

authors： Öhman T,Gawriyski L,Miettinen S,Varjosalo M,Loukovaara S

更新日期：2021-01-13 00:00:00

abstract：:Triple-negative breast cancers (TNBC) are unlikely to respond to hormonal therapies and anti-HER2-targeted therapies. TNBCs overexpress EGFR and exhibit constitutive activation of the PI3K/AKT/mTOR signalling pathway. We hypothesized that simultaneously blocking EGFR and mTOR could be a potential therapeutic strategy ...

journal_title：Scientific reports

authors： El Guerrab A,Bamdad M,Bignon YJ,Penault-Llorca F,Aubel C

更新日期：2020-04-14 00:00:00

abstract：:We report on the intriguing evolution of the dynamical spin correlations of the frustrated spinel ZnMn2O4. Inelastic neutron scattering and magnetization studies reveal that the dynamical correlations at high temperatures are 1D. At lower temperature, these dynamical correlations become 2D. Surprisingly, the dynamical...

journal_title：Scientific reports

authors： Disseler SM,Chen Y,Yeo S,Gasparovic G,Piccoli PM,Schultz AJ,Qiu Y,Huang Q,Cheong SW,Ratcliff W

更新日期：2015-12-08 00:00:00