Diabetes in Menopause: Risks and Management.

abstract：INTRODUCTION:Obstructive Sleep Apnoea (OSA) constitutes the most prevalent form of abnormal respiratory control during sleep in adults. Evidence linked OSA to cardiovascular disease, and the role of OSA in abnormal Blood Pressure (BP) control has been extensively studied. Although longitudinal trials suggest a causativ...

journal_title：Current vascular pharmacology

authors： Wolf J,Narkiewicz K

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Aging-associated vascular dysfunction promotes cardiovascular diseases. Recently, Ginkgo biloba extract (GBE) has attracted considerable attention in the prevention of aged vasculature. METHODS:This review discusses the pathophysiological alterations in aged vasculature and the underlying mechanisms of GBE ...

journal_title：Current vascular pharmacology

authors： Li X,Lu L,Chen J,Zhang C,Chen H,Huang H

更新日期：2020-01-01 00:00:00

abstract：:Revascularization procedures used for the treatment of cardiovascular disease can be associated with restenosis, although drug-coated stents have greatly reduced this complication. Both type 2 diabetes (T2DM) and metabolic syndrome (MetS) are associated with a high risk for atherosclerosis and restenosis. Insulin resi...

journal_title：Current vascular pharmacology

authors： Breen DM,Giacca A

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Add-on therapy with the Mineralocorticoid-Receptor-Antagonists (MRAs) spironolactone and eplerenone was shown to enhance the cardioprotective action of angiotensinconverting- enzyme-inhibitors (ACEIs), angiotensin-receptor-blockers (ARBs) and/or β-blockers in nondialysis patients with congestive heart failur...

journal_title：Current vascular pharmacology

authors： Georgianos PI,Vaios V,Eleftheriadis T,Zebekakis P,Liakopoulos V

更新日期：2017-01-01 00:00:00

abstract：:Cell-based therapies are a novel approach for regeneration of microvasculature. We have shown that administration of CD34-positive cells, the rich cell fraction of endothelial progenitor cells, after stroke induces angiogenesis that results in enhanced endogenous neurogenesis and functional recovery in a murine model....

journal_title：Current vascular pharmacology

authors： Uemura M,Kasahara Y,Nagatsuka K,Taguchi A

更新日期：2012-05-01 00:00:00

abstract：:Obstructive sleep apnoea (OSA) is characterized by repetitive interruptions of breathing, causing Chronic Intermittent Hypoxia (CIH) that can be involved in the development and progression of cardiovascular diseases. There is evidence showing a close relationship between OSA and atherosclerosis, even in patients who d...

journal_title：Current vascular pharmacology

authors： Toraldo DM,Benedetto M,Conte L,De Nuccio F

更新日期：2017-01-01 00:00:00

abstract：:Aspirin plays a pivotal role in the management of patients with Coronary Artery Disease (CAD) with well-recognised benefits of reducing recurrent myocardial infarction and minimising the risk of stent thrombosis for those undergoing Percutaneous Coronary Intervention (PCI). Dual antiplatelet therapy is mandated for pa...

journal_title：Current vascular pharmacology

authors： Kassimis G,Raina T,Alexopoulos D

更新日期：2019-01-01 00:00:00

abstract：:Tertiary amine local anesthetics (LAs) are clinically valuable agents for controlling pain and for treating some cardiac arrhythmias. These drugs inhibit conduction of electrical activity by blocking voltage-gated sodium channels. Interestingly, LAs can influence the conduction of electrical activity in heart muscle w...

journal_title：Current vascular pharmacology

authors： Wright SN

更新日期：2003-10-01 00:00:00

abstract：:Post-transplant diabetes mellitus (PTDM) and dyslipidaemia are the most common metabolic complications in kidney transplant recipients (KTR). They are associated with a higher risk of lower graft function and survival, as well as an increased risk of cardiovascular disease (CVD). The aim of this review is to provide c...

journal_title：Current vascular pharmacology

authors： Anagnostis P,Paschou SA,Spartalis E,Sarno G,De Rosa P,Muscogiuri G

更新日期：2020-01-01 00:00:00

abstract：:Chronic venous disease (CVeD) is a debilitating condition that affects millions of individuals worldwide. The condition can result in varicose veins, or advance to severe skin changes and venous ulceration. The fundamental basis for CVeD is inflammation within the venous circulation and that it is subjected to increas...

journal_title：Current vascular pharmacology

authors： Mannello F,Ligi D,Canale M,Raffetto JD

更新日期：2014-01-01 00:00:00

abstract：:In the last decade there have been considerable advances in the understanding of the pathophysiology of malignant ventricular tachyarrhythmias (VA) and Sudden Cardiac Death (SCD). Over 80% of SCD occurs in patients with organic heart disease. However, approximately 10-15% of SCD occurs in the presence of structurally ...

journal_title：Current vascular pharmacology

authors： El-Sherif N,Pedalino R,Himel H 4th

更新日期：2009-07-01 00:00:00

abstract：:In recent years, the development of more effective drugs has provided a better prognosis and an increase in life expectancy for patients at all-stages of cancer. On the other hand, the price for the improving effectiveness of therapies against malignant tumors is the development of severe and potentially life-threaten...

journal_title：Current vascular pharmacology

authors： Perrino C,Schiattarella GG,Magliulo F,Ilardi F,Carotenuto G,Gargiulo G,Serino F,Ferrone M,Scudiero F,Carbone A,Trimarco B,Esposito G

更新日期：2014-01-01 00:00:00

abstract：:Chronic kidney disease (CKD), and particularly kidney failure, is associated with accelerated atherosclerosis and approximately a 20-fold increased risk of cardiovascular death. The majority of these patients die from complications directly attributed to atherosclerosis and their life expectancy is decreased. Establis...

journal_title：Current vascular pharmacology

authors： Efstratiadis G,Tziomalos K,Mikhailidis DP,Athyros VG,Hatzitolios A

更新日期：2008-04-01 00:00:00

abstract：:Bladder outlet obstruction (BOO) is a common disorder that is associated with urinary tract symptoms. Nitric oxide (NO), synthesized by NO synthase (NOS) is a potent vasodilator that is present throughout the urinary tract and the corpus cavernosum. Endothelin-1 (ET-1) conversely is a potent vasoconstrictor peptide th...

journal_title：Current vascular pharmacology

authors： Khan MA,Thompson CS,Dashwood MR,Mumtaz FH,Morgan RJ,Mikhailidis DP

更新日期：2003-03-01 00:00:00

abstract：:Fifteen years after its discovery, NO has fully reached an established position in physiology, medicine and therapeutics. It is difficult to find a biological function or a pathological condition where NO does not play a relevant role. Discoveries in the NO field have historically evolved from cardiovascular research,...

journal_title：Current vascular pharmacology

authors： Llorens S,Nava E

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Single-pill fixed dose combination (FDC) therapies are widely used in the treatment of arterial hypertension. OBJECTIVE:This pilot study aimed to evaluate the effects of a FDC therapy combined with therapeutic drug monitoring (TDM) on blood pressure (BP) in patients with treatment resistant hypertension. M...

journal_title：Current vascular pharmacology

authors： Kreutz R,Scholze J,Douros A

更新日期：2018-01-26 00:00:00

abstract：:High density lipoprotein (HDL) is recognized as the major negative risk factor of cardiovascular disease and number of anti-atherogenic functions has been ascribed to HDL. HDL is an assembly of a neutral lipid core and an outer shell consisting of polar lipids and proteins. It has been defined many different ways base...

journal_title：Current vascular pharmacology

authors： Vaisar T

更新日期：2012-07-01 00:00:00

abstract：:Postprandial hypertriglyceridaemia, defined as an increase in plasma triglyceride-containing lipoproteins following a fat meal, is a potential risk predictor of atherosclerotic cardiovascular disease and other chronic diseases. Several non-modifiable factors (genetics, age, sex and menopausal status) and lifestyle fac...

journal_title：Current vascular pharmacology

authors： Kolovou GD,Watts GF,Mikhailidis DP,Pérez-Martínez P,Mora S,Bilianou H,Panotopoulos G,Katsiki N,Ooi TC,Lopez-Miranda J,Tybjærg-Hansen A,Tentolouris N,Nordestgaard BG

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Non-alcoholic fatty liver disease (NAFLD) affects a large proportion of the general population. The disease ranges from simple steatosis, to non-alcoholic steatohepatitis (NASH), cirrhosis and even hepatocellular carcinoma. Several drugs are used in daily clinical practice to manage the disease. However, dat...

journal_title：Current vascular pharmacology

authors： Imprialos K,Stavropoulos K,Bouloukou S,Kerpiniotis G,Karagiannis A,Doumas M

更新日期：2018-01-01 00:00:00

abstract：:An inverse association between diabetes mellitus (DM) and abdominal aortic aneurysm (AAA) risk have been reported. Apart from a lower AAA prevalence among patients with vs without DM, there are data showing that DM may exert a protective role on aneurysmal growth in patients with small AAAs, thus decreasing the risk o...

journal_title：Current vascular pharmacology

authors： Radak D,Tanaskovic S,Katsiki N,Isenovic ER

更新日期：2016-01-01 00:00:00

abstract：:The hypothesis of 'Developmental Origins of Health and Disease' (DOHaD) relies on the presence of mechanisms sensing and signalling a diversity of stimuli during fetal development. The mechanisms that have been broadly suggested to be involved in these processes are the epigenetic modifications that could 'record' per...

journal_title：Current vascular pharmacology

authors： Krause B,Sobrevia L,Casanello P

更新日期：2009-10-01 00:00:00

abstract：:Urocortin comprises a group of endogenously produced peptide hormones that belong to the corticotropinreleasing factor (CRF) family with promising future as potential drugs for the treatment of heart disease. Members of the urocortin family are known to act as potent regulators of cardiac and vascular functions, throu...

journal_title：Current vascular pharmacology

authors： Díaz I,Smani T

更新日期：2013-07-01 00:00:00

abstract：:Cardiovascular failure in sepsis involves a combination of hypovolemia, decreased vascular tone, myocardial depression and microcirculatory alterations. Fluids represent the first line therapeutic intervention, with controversy regarding the type of fluid. Recent data indicate that albumin is safe and might even be be...

journal_title：Current vascular pharmacology

authors： De Backer D,Scolletta S

更新日期：2013-03-01 00:00:00

abstract：:Platelet activation induces rapid thrombus formation at a ruptured atherosclerotic plaque leading to acute vessel occlusion and a fatal or non-fatal cardiovascular event. More recent evidence suggests that activated platelets play an additional central role during the initiation of atherosclerosis, essentially facilit...

journal_title：Current vascular pharmacology

authors： Schäfer A,Bauersachs J

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Kallistatin (KS) is a serine proteinase. The result of KS on 'Renal Ischemia- Reperfusion Injury' (IRI) has not clearly been researched. In this study, investigative research has been conducted to draw results on the administration of human KS on kidney response conducted within a mouse model of IRI. MATERI...

journal_title：Current vascular pharmacology

authors： Zhou S,Sun Y,Zhuang Y,Zhao W,Chen Y,Jiang B,Guo C,Zhang Z,Peng H,Chen Y

更新日期：2015-01-01 00:00:00

abstract：:Biomarkers are used in medicine to facilitate diagnosis, assess risk, direct therapy and determine efficacy of treatment. Sensitivity and specificity are essential in order for a biomarker to be useful. Brain natriuretic peptide (BNP) and C-reactive protein (CRP) are considered biomarkers of cardiovascular disease. Ho...

journal_title：Current vascular pharmacology

authors： Miller VM,Redfield MM,McConnell JP

更新日期：2007-01-01 00:00:00

abstract：:Normal pregnancy is associated with increased insulin resistance as a metabolic adaptation to the nutritional demands of the placenta and fetus, and this is amplified in obese mothers. Insulin resistance is normally compensated for by an adaptive increase in pancreatic β-cell mass together with enhanced glucose-stimul...

journal_title：Current vascular pharmacology

authors： Szlapinski SK,Hill DJ

更新日期：2021-01-01 00:00:00

abstract：:The incidence of cardiovascular disease is low in healthy premenopausal women and increases with age especially after the menopause; this difference has been attributed to the loss of endogenous estrogen. Atherosclerosis is a chronic inflammatory condition of the vascular wall that may result in an acute clinical even...

journal_title：Current vascular pharmacology

authors： Bechlioulis A,Naka KK,Calis KA,Makrigiannakis A,Michalis L,Kalantaridou SN

更新日期：2010-03-01 00:00:00

abstract：:Platelet aggregation induced by stirring of a platelet suspension after activation by the exogenous addition of stimulants, such as ADP, epinephrine and thrombin, has long been used as a platelet function test, and for the screening of antiplatelet agents. Since platelet aggregation has been demonstrated to be mediate...

journal_title：Current vascular pharmacology

authors： Goto S

更新日期：2004-01-01 00:00:00

abstract：:Prostaglandins (PGs) belong to the family of prostanoids together with thromboxanes and are produced mainly from arachadonic acid by the enzyme cyclooxygenase. PGs are known to stimulate platelet aggregation, mediate inflammation and edema, play a role in bone metabolism and in biological adaptation of connective tiss...

journal_title：Current vascular pharmacology

authors： Boushel R,Langberg H,Risum N,Kjaer M

更新日期：2004-04-01 00:00:00