Y-box protein-associated acidic protein (YBAP1/C1QBP) affects the localization and cytoplasmic functions of YB-1.

abstract：:The use of metabolomic and lipidomic strategies for selecting potential biomarkers for obstructive sleep apnoea (OSA) has been little explored. We examined adult male patients with OSA (defined by an apnoea-hypopnoea index ≥15 events/hour), as well as age-, gender-, and fat-composition-matched volunteers without OSA. ...

journal_title：Scientific reports

authors： Lebkuchen A,Carvalho VM,Venturini G,Salgueiro JS,Freitas LS,Dellavance A,Martins FC,Lorenzi-Filho G,Cardozo KHM,Drager LF

更新日期：2018-07-26 00:00:00

abstract：:Abnormal dopaminergic transmission has been implicated as a risk determinant of HIV-1-associated neurocognitive disorders. HIV-1 Tat protein increases synaptic dopamine (DA) levels by directly inhibiting DA transporter (DAT) activity, ultimately leading to dopaminergic neuron damage. Through integrated computational m...

journal_title：Scientific reports

authors： Quizon PM,Sun WL,Yuan Y,Midde NM,Zhan CG,Zhu J

更新日期：2016-12-14 00:00:00

abstract：:Photoacoustic (optoacoustic) imaging can visualize vasculature deep in tissue using the high contrast of hemoglobin to light, with the high-resolution possible with ultrasound detection. Since angiogenesis, one of the hallmarks of cancer, leads to increased vascularity, photoacoustics holds promise in imaging breast c...

journal_title：Scientific reports

authors： Heijblom M,Piras D,Brinkhuis M,van Hespen JC,van den Engh FM,van der Schaaf M,Klaase JM,van Leeuwen TG,Steenbergen W,Manohar S

更新日期：2015-07-10 00:00:00

abstract：:The discovery of single-phase multiferroic materials and the understanding of coupling mechanisms between their spin and polarization is important from the point of view of next generation logic and memory devices. Herein we report the fabrication, dielectric, ferroelectric, piezo-response force microscopy, and magnet...

journal_title：Scientific reports

authors： Mishra KK,Instan AA,Kumari S,Scott JF,Katiyar RS

更新日期：2020-02-19 00:00:00

abstract：:Buccal mucosa squamous cell carcinoma (BMSCC) is one of major subsites of oral cancer and is associated with a high rate of metastasis and poor prognosis. Heat shock proteins (HSPs) act as potential prognostic biomarkers in many cancer types. However, the role of HSPD1 in oral cancer, especially in BMSCC, is still unk...

journal_title：Scientific reports

authors： Kang BH,Shu CW,Chao JK,Lee CH,Fu TY,Liou HH,Ger LP,Liu PF

更新日期：2019-06-20 00:00:00

abstract：:Some studies have demonstrated interactions of AD-risk single nucleotide polymorphisms (SNPs) in non-APOE regions with APOE genotype. Nevertheless, no study reported interactions of expression quantitative trait locus (eQTL) for APOE with APOE genotype. In present study, we included 9286 unrelated AD patients and 8479...

journal_title：Scientific reports

authors： Zhang A,Zhao Q,Xu D,Jiang S

更新日期：2018-05-23 00:00:00

abstract：:Patient-matched transcriptomic studies using tumour samples before and after treatment allow inter-patient heterogeneity to be controlled, but tend not to include an untreated comparison. Here, Illumina BeadArray technology was used to measure dynamic changes in gene expression from thirty-seven paired diagnostic core...

journal_title：Scientific reports

authors： Pearce DA,Arthur LM,Turnbull AK,Renshaw L,Sabine VS,Thomas JS,Bartlett JM,Dixon JM,Sims AH

更新日期：2016-07-07 00:00:00

abstract：:This study aims to determine the prevalence of health personnel with normal weight central obesity and to investigate whether this group had higher cardiovascular disease (CVD) risk factors than those of the people with normal weight and without central obesity. A waist-to-height ratio was calculated as waist circumfe...

journal_title：Scientific reports

authors： Thaikruea L,Thammasarot J

更新日期：2016-11-16 00:00:00

abstract：:3,4-Methylenedioxymethamphetamine (MDMA), a common recreational drug, is known to cause serotonergic neurotoxicity in the brain. Dextromethorphan (DM) is a widely used antitussive reported to exert anti-inflammatory effect in vivo. In this study, we examined the long-term effect of MDMA on the primate serotonergic sys...

journal_title：Scientific reports

authors： Ma KH,Liu TT,Weng SJ,Chen CF,Huang YS,Chueh SH,Liao MH,Chang KW,Sung CC,Hsu TH,Huang WS,Cheng CY

更新日期：2016-12-12 00:00:00

abstract：:The mechanism by which chronic metabolic acidosis (CMA) regulates sodium (Na(+))-chloride (Cl(-)) cotransporter (NCC) in the renal distal convoluted tubules remains unexplored. We examined the role of STE20/SPS1-related proline/alanine-rich kinase (SPAK) and with-no-lysine kinase 4 (WNK4) on expression of NCC in mouse...

journal_title：Scientific reports

authors： Fang YW,Yang SS,Cheng CJ,Tseng MH,Hsu HM,Lin SH

更新日期：2016-01-05 00:00:00

abstract：:Ball-milling utilizes mechanical stress to modify properties of carbon nanotubes (CNTs) including size, capping, and functionalization. Ball-milling, however, may introduce structural defects resulting in altered CNT-biomolecule interactions. Nanomaterial-biomolecule interactions result in the formation of the biocoro...

journal_title：Scientific reports

authors： Raghavendra AJ,Fritz K,Fu S,Brown JM,Podila R,Shannahan JH

更新日期：2017-08-16 00:00:00

abstract：:Embryonic stem cells (ESCs) and epiblast-like cells (EpiLCs) recapitulate in vitro the epiblast first cell lineage decision, allowing characterization of the molecular mechanisms underlying pluripotent state transition. Here, we performed a comprehensive and comparative analysis of total glycomes of mouse ESCs and Epi...

journal_title：Scientific reports

authors： Pecori F,Yokota I,Hanamatsu H,Miura T,Ogura C,Ota H,Furukawa JI,Oki S,Yamamoto K,Yoshie O,Nishihara S

更新日期：2021-01-14 00:00:00

abstract：:Brain insulin sensitivity is an important link between metabolism and cognitive dysfunction. Intranasal insulin is a promising tool to investigate central insulin action in humans. We evaluated the acute effects of 160 U intranasal insulin on resting-state brain functional connectivity in healthy young adults. Twenty-...

journal_title：Scientific reports

authors： Kullmann S,Heni M,Veit R,Scheffler K,Machann J,Häring HU,Fritsche A,Preissl H

更新日期：2017-05-09 00:00:00

abstract：:Terrestrial microbial ecosystems are exposed to many types of disturbances varying in their spatial and temporal characteristics. The ability to cope with these disturbances is crucial for maintaining microbial ecosystem functions, especially if disturbances recur regularly. Thus, understanding microbial ecosystem dyn...

journal_title：Scientific reports

authors： König S,Worrich A,Banitz T,Centler F,Harms H,Kästner M,Miltner A,Wick LY,Thullner M,Frank K

更新日期：2018-06-22 00:00:00

abstract：:Solute segregating to grain boundary can stabilize the microstructure of nanocrystalline materials, but a lot of solutes also cause embrittlement effect on interfacial strength. Therefore, uncovering the solute effect on grain boundary strength is very important for nanocrystalline alloys design. In this work, we have...

journal_title：Scientific reports

authors： Huang Z,Wang P,Chen F,Shen Q,Zhang L

更新日期：2020-10-08 00:00:00

abstract：:Phenotypic plasticity describes the ability of a given genotype to produce distinct phenotypes in different environments. We use the temperature sensitivity of abdominal pigmentation in Drosophila melanogaster females as a model to analyse the effect of the environment on development. We reported previously that therm...

journal_title：Scientific reports

authors： Gibert JM,Mouchel-Vielh E,Peronnet F

更新日期：2017-02-23 00:00:00

abstract：:CD31hiEmcnhi vessels were a subtype of vessels in the murine skeletal system, with high levels of platelet and endothelial cell adhesion molecule-1 (PECAM-1/CD31) and endomucin (Emcn). They were reported coupling angiogenesis and osteogenesis during bone development. We investigated the distribution of these vessels i...

journal_title：Scientific reports

authors： Wang J,Gao Y,Cheng P,Li D,Jiang H,Ji C,Zhang S,Shen C,Li J,Song Y,Cao T,Wang C,Yang L,Pei G

更新日期：2017-07-10 00:00:00

abstract：:In this article we show that diffraction segregates the polarization singularities according to their handedness. Polarization singularities are superpositions of left and right handed circular polarization vortex states. In the superposition, the component states possess different orbital angular momenta depending on...

journal_title：Scientific reports

authors： Deepa S,B S BR,Senthilkumaran P

更新日期：2019-08-28 00:00:00

abstract：:Antenna systems serve to absorb light and to transmit excitation energy to the reaction center (RC) in photosynthetic organisms. As the emitted (bacterio)chlorophyll fluorescence competes with the photochemical utilization of the excitation, the measured fluorescence yield is informed by the migration of the excitatio...

journal_title：Scientific reports

authors： Maróti P,Kovács IA,Kis M,Smart JL,Iglói F

更新日期：2020-08-19 00:00:00

abstract：:Colloidal particles immersed in a dynamic speckle pattern experience an optical force that fluctuates both in space and time. The resulting dynamics presents many interesting analogies with a broad class of non-equilibrium systems like: active colloids, self propelled microorganisms, transport in dynamical intracellul...

journal_title：Scientific reports

authors： Bianchi S,Pruner R,Vizsnyiczai G,Maggi C,Di Leonardo R

更新日期：2016-06-09 00:00:00

abstract：:Quantum phase transition is one of the most interesting aspects in quantum many-body systems. Recently, geometric quantum discord has been introduced to signature the critical behavior of various quantum systems. However, it is well-known that topological quantum phase transition can not be described by the convention...

journal_title：Scientific reports

authors： Shan CJ,Cheng WW,Liu JB,Cheng YS,Liu TK

更新日期：2014-03-26 00:00:00

abstract：:Hyperuricemia is an abnormal metabolic condition characterized by an increase in uric acid levels in the blood. It is the cause of gout, manifested by inflammatory arthritis, pain and disability. This study examined the possible ameliorative impacts of parsley (PAR) and celery (CEL) as hypouricemic agents at biochemic...

journal_title：Scientific reports

authors： Soliman MM,Nassan MA,Aldhahrani A,Althobaiti F,Mohamed WA

更新日期：2020-06-11 00:00:00

abstract：:Transmembrane receptor clustering is a ubiquitous phenomenon in pro- and eukaryotic cells to physically sense receptor/ligand interactions and subsequently translate an exogenous signal into a cellular response. Despite that receptor cluster formation has been described for a wide variety of receptors, ranging from ch...

journal_title：Scientific reports

authors： Becker B,Shaebani MR,Rammo D,Bubel T,Santen L,Schmitt MJ

更新日期：2016-06-29 00:00:00

abstract：:Adult Cebpb KO mice incisors present amelogenin-positive epithelium pearls, enamel and dentin allopathic hyperplasia, fewer Sox2-positive cells in labial cervical loop epitheliums, and reduced Sox2 expression in enamel epithelial stem cells. Thus, Cebpb acts upstream of Sox2 to regulate stemness. In this study, Cebpb ...

journal_title：Scientific reports

authors： Saito K,Takahashi K,Huang B,Asahara M,Kiso H,Togo Y,Tsukamoto H,Mishima S,Nagata M,Iida M,Tokita Y,Asai M,Shimizu A,Komori T,Harada H,MacDougall M,Sugai M,Bessho K

更新日期：2018-03-26 00:00:00

abstract：:Thrombosis has proven to be extremely difficult to predict. Measuring the generation of thrombin is a very sensitive method to detect changes in the hemostatic system. We developed a method based on the generation of thrombin to further fingerprint hemostasis, which we have named thrombin dynamics. Via this method we ...

journal_title：Scientific reports

authors： de Laat-Kremers RMW,Yan Q,Ninivaggi M,de Maat M,de Laat B

更新日期：2020-07-27 00:00:00

abstract：:Biochar can influence native soil organic carbon (SOC) mineralisation through "priming effects". However, the long-term direction, persistence and extent of SOC priming by biochar remain uncertain. Using natural (13)C abundance and under controlled laboratory conditions, we show that biochar-stimulated SOC mineralisat...

journal_title：Scientific reports

authors： Singh BP,Cowie AL

更新日期：2014-01-21 00:00:00

abstract：:Targeting embryonic stem cells (ESCs) is important for ESC labeling, drug delivery and cell fate control. In this study, we identified twenty-two phage clones that bind specifically to the hESC cell line X-01, which was derived from human blastocysts of Chinese origin. One phage (H178), which displays the sequence VGG...

journal_title：Scientific reports

authors： Zhao W,Jin L,Yuan H,Tan Z,Zhou C,Li LS,Ma L

更新日期：2013-11-05 00:00:00

abstract：:Synthetic analogues of mycobacterial trehalose-dimycolate such as trehalose acyl esters have been proposed as novel adjuvants for vaccination. They induce an immune response by binding to the macrophage C-type lectin receptor Mincle. The binding site of trehalose is known, but there is yet only very limited structural...

journal_title：Scientific reports

authors： Söldner CA,Horn AHC,Sticht H

更新日期：2018-03-29 00:00:00

abstract：:Enzymatic conversion of chitin, a β-1,4 linked polymer of N-acetylglucosamine, is of major interest in areas varying from the biorefining of chitin-rich waste streams to understanding how medically relevant fungi remodel their chitin-containing cell walls. Although numerous chitinolytic enzymes have been studied in de...

journal_title：Scientific reports

authors： Liu Z,Gay LM,Tuveng TR,Agger JW,Westereng B,Mathiesen G,Horn SJ,Vaaje-Kolstad G,van Aalten DMF,Eijsink VGH

更新日期：2017-05-11 00:00:00

abstract：:Mullite nanowhiskers are prepared by a facile technique at low temperature using mica and AlF3 as raw material. Mica acts as reactant as well as substrate. By controlling the reaction temperature and holding time, the mullite nanowhisker array with uniform morphology is obtained. The nanowhisker array possesses Al-ric...

journal_title：Scientific reports

authors： Yang T,Wang E,Wang F,Chou K,Hou X

更新日期：2015-04-13 00:00:00